| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F C Brunicardi, P Druck, Y S Sun, D Elahi, R L Gingerich, D K Anderse. Regulation of pancreatic polypeptide secretion in the isolated perfused human pancreas. American journal of surgery. vol 155. issue 1. 1988-03-02. PMID:3277467. |
since the immunoreactive pancreatic polypeptide response was augmented when insulin and somatostatin release was inhibited by perfusion insulin or nerve stimulation, we conclude that the pancreatic polypeptide cell is regulated by the ambient degree of somatostatin release, insulin release, or both. |
1988-03-02 |
2023-08-11 |
human |
| J Schmidtler, P O Schwill. Influence of 70 percent pancreatic resection on serum and bone calcium in the rat--a preliminary report. Hepato-gastroenterology. vol 34. issue 6. 1988-03-02. PMID:3428861. |
additionally, residual pancreatic amylase content, fasting blood levels of insulin, glucagon, somatostatin and glucose were determined, and the mineral balance (calcium, phosphate) studied. |
1988-03-02 |
2023-08-11 |
rat |
| Y Ohaki, K Misugi, J Fukuda, M Okudaira, M Hiros. Immunohistochemical study of pancreatoblastoma. Acta pathologica japonica. vol 37. issue 10. 1988-02-29. PMID:2449037. |
also, endocrine substances including insulin, glucagon and somatostatin were all negative in the pancreatoblastomas. |
1988-02-29 |
2023-08-11 |
Not clear |
| K H Johnson, T D O'Brien, D W Hayden, K Jordan, H K Ghobrial, W C Mahoney, P Westermar. Immunolocalization of islet amyloid polypeptide (IAPP) in pancreatic beta cells by means of peroxidase-antiperoxidase (PAP) and protein A-gold techniques. The American journal of pathology. vol 130. issue 1. 1988-02-25. PMID:3276206. |
in the present investigation, the authors utilized antisera to insulin, glucagon, somatostatin, pancreatic polypeptide, synthetic human cgrp, and a synthetic human iapp (7-17) undecapeptide to immunohistochemically (pap technique) document the presence of iapp immunoreactive cells in the islets of the cat, dog, mouse, and rat, but not in the islets of the horse or calf. |
1988-02-25 |
2023-08-11 |
mouse |
| M J Müller, J Möring, H J Seit. Regulation of hepatic glucose output by glucose in vivo. Metabolism: clinical and experimental. vol 37. issue 1. 1988-02-20. PMID:2892114. |
glucose turnover was estimated by the use of 3-h-glucose before and during glucose infusion where the contribution of the glucose-induced hormonal changes were estimated by infusing glucose plus somatostatin with or without insulin and/or glucagon substitution. |
1988-02-20 |
2023-08-11 |
Not clear |
| V E Gould, G Chejfec, K Shah, E Paloyan, A M Lawrenc. Adult nesidiodysplasia. Seminars in diagnostic pathology. vol 1. issue 1. 1988-02-20. PMID:6400629. |
tissue samples were studied by light microscopy and light microscopic immunohistochemistry for serotonin, acth, bombesin, calcitonin, gastrin, glucagon, insulin, hpp, somatostatin, and vip. |
1988-02-20 |
2023-08-12 |
Not clear |
| V E Gould, G Chejfec, K Shah, E Paloyan, A M Lawrenc. Adult nesidiodysplasia. Seminars in diagnostic pathology. vol 1. issue 1. 1988-02-20. PMID:6400629. |
immunoreactivity for insulin, glucagon, and somatostatin was demonstrated in all cases; the ratio among these hormones in the patients with endocrine dysfunction and in the controls was similar. |
1988-02-20 |
2023-08-12 |
Not clear |
| V E Gould, G Chejfec, K Shah, E Paloyan, A M Lawrenc. Adult nesidiodysplasia. Seminars in diagnostic pathology. vol 1. issue 1. 1988-02-20. PMID:6400629. |
in the patients with hyperinsulinemic hypoglycemia, step sections sequentially stained for insulin and somatostatin showed a close topographic relationship between these cell types. |
1988-02-20 |
2023-08-12 |
Not clear |
| V E Gould, G Chejfec, K Shah, E Paloyan, A M Lawrenc. Adult nesidiodysplasia. Seminars in diagnostic pathology. vol 1. issue 1. 1988-02-20. PMID:6400629. |
we suggest that the hyperinsulinemic hypoglycemia in these adults was not due to simple quantitative abnormalities in total endocrine cell mass nor to its maldistribution nor to lack of topographic proximity between insulin and somatostatin cells. |
1988-02-20 |
2023-08-12 |
Not clear |
| S W Lambert. A guide to the clinical use of the somatostatin analogue SMS 201-995 (Sandostatin). Acta endocrinologica. Supplementum. vol 286. 1988-02-17. PMID:2892338. |
sms 201-995 (sandostatin) is an octapeptide which differs in its action from native somatostatin in four ways: 1) it inhibits gh hormone secretion in preference to insulin secretion; 2) it can be administered subcutaneously or even orally; 3) it is long-acting (t1/2 after sc administration 113 min), and 4) there is no rebound hypersecretion of hormones when the effect of the analogue lingers off. |
1988-02-17 |
2023-08-11 |
Not clear |
| R Berzins, K R Wieczorek, R V Rajotte, G D Molnar, Y K Tam, J R McGregor, D M Fawcet. Accuracy of C-peptide:insulin molar ratio as a measure of hepatic removal of insulin. Diabetes research and clinical practice. vol 4. issue 1. 1988-01-28. PMID:2891470. |
in anesthetized dogs (n = 6), during electromagnetic hepatic blood flow monitoring, endogenous insulin was suppressed with somatostatin, while equimolar proportions of porcine insulin and simian c-peptide (2.4 and 6.0 pmol/kg.min) were infused during two consecutive 45-min periods. |
1988-01-28 |
2023-08-11 |
Not clear |
| V Leclercq-Meyer, M C Woussen-Colle, C Lalieu, J Marchand, W J Malaiss. Anomeric specificity of glucose-induced somatostatin secretion. Experientia. vol 43. issue 11-12. 1988-01-26. PMID:2891561. |
in isolated perfused rat pancreases, the alpha-anomer of d-glucose is more potent than beta-d-glucose not solely in stimulating insulin release and suppressing glucagon output, but also in causing somatostatin secretion. |
1988-01-26 |
2023-08-11 |
rat |
| M L Brandi, C M Rotella, C Mavilia, F Franceschelli, A Tanini, R Toccafond. Insulin stimulates cell growth of a new strain of differentiated rat thyroid cells. Molecular and cellular endocrinology. vol 54. issue 1. 1988-01-15. PMID:2824250. |
the primary culture was grown in coon's modified ham's f12 medium with 5% calf serum, insulin, hydrocortisone, transferrin, somatostatin, glycyl-l-histidyl-l-lysine and thyrotropin (tsh). |
1988-01-15 |
2023-08-11 |
rat |
| A R Diani, G A Sawada, B A Hannah, K S Jodelis, M A Connell, C L Connell, T J Vidmar, B M Wys. Analysis of pancreatic islet cells and hormone content in the spontaneously diabetic KKAy mouse by morphometry, immunocytochemistry and radioimmunoassay. Virchows Archiv. A, Pathological anatomy and histopathology. vol 412. issue 1. 1988-01-13. PMID:2446417. |
the insulin cells of the diabetic mice were severely degranulated and many of the glucagon, somatostatin and pancreatic polypeptide cells were displaced from the mantle to the core of the islet tissue where the non-insulin cells appeared to lose their continuity. |
1988-01-13 |
2023-08-11 |
mouse |
| A R Diani, G A Sawada, B A Hannah, K S Jodelis, M A Connell, C L Connell, T J Vidmar, B M Wys. Analysis of pancreatic islet cells and hormone content in the spontaneously diabetic KKAy mouse by morphometry, immunocytochemistry and radioimmunoassay. Virchows Archiv. A, Pathological anatomy and histopathology. vol 412. issue 1. 1988-01-13. PMID:2446417. |
the volume and numerical percents of the insulin cells were significantly increased whereas those of the glucagon and somatostatin cells were decreased in the kkay mice. |
1988-01-13 |
2023-08-11 |
mouse |
| A R Diani, G A Sawada, B A Hannah, K S Jodelis, M A Connell, C L Connell, T J Vidmar, B M Wys. Analysis of pancreatic islet cells and hormone content in the spontaneously diabetic KKAy mouse by morphometry, immunocytochemistry and radioimmunoassay. Virchows Archiv. A, Pathological anatomy and histopathology. vol 412. issue 1. 1988-01-13. PMID:2446417. |
pancreatic insulin and somatostatin contents were markedly diminished in the islets of kkay compared with those of c57bl/6 mice. |
1988-01-13 |
2023-08-11 |
mouse |
| E J Verspohl, H P Ammo. Cholecystokinin (CCK8) regulates glucagon, insulin, and somatostatin secretion from isolated rat pancreatic islets: interaction with glucose. Pflugers Archiv : European journal of physiology. vol 410. issue 3. 1988-01-12. PMID:2891102. |
cholecystokinin (cck8) regulates glucagon, insulin, and somatostatin secretion from isolated rat pancreatic islets: interaction with glucose. |
1988-01-12 |
2023-08-11 |
rat |
| E J Verspohl, H P Ammo. Cholecystokinin (CCK8) regulates glucagon, insulin, and somatostatin secretion from isolated rat pancreatic islets: interaction with glucose. Pflugers Archiv : European journal of physiology. vol 410. issue 3. 1988-01-12. PMID:2891102. |
the effect of cck8 on glucagon, insulin and somatostatin release and its interaction with glucose was studied in freshly isolated rat pancreatic islets. |
1988-01-12 |
2023-08-11 |
rat |
| A Secchi, A E Pontiroli, E Bosi, P M Piatti, J L Touraine, L D Monti, A Gelet, J Traeger, J M Dubernard, G Pozz. Effects of arginine and arginine plus somatostatin infusion on insulin release in diabetic patients submitted to pancreas allotransplantation. Diabete & metabolisme. vol 13. issue 4. 1988-01-11. PMID:2890540. |
effects of arginine and arginine plus somatostatin infusion on insulin release in diabetic patients submitted to pancreas allotransplantation. |
1988-01-11 |
2023-08-11 |
human |
| b' M Gutniak, S G Karlander, S Efendi\\xc4\\x8. Glyburide decreases insulin requirement, increases beta-cell response to mixed meal, and does not affect insulin sensitivity: effects of short- and long-term combined treatment in secondary failure to sulfonylurea. Diabetes care. vol 10. issue 5. 1988-01-07. PMID:2890501.' |
the subjects underwent normoglycemic clamp studies and meal tests with determination of insulin, c-peptide, glucagon, somatostatin, and gastric inhibitory polypeptide in plasma. |
1988-01-07 |
2023-08-11 |
human |