| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| V E Gould, G Chejfec, K Shah, E Paloyan, A M Lawrenc. Adult nesidiodysplasia. Seminars in diagnostic pathology. vol 1. issue 1. 1988-02-20. PMID:6400629. |
in the patients with hyperinsulinemic hypoglycemia, step sections sequentially stained for insulin and somatostatin showed a close topographic relationship between these cell types. |
1988-02-20 |
2023-08-12 |
Not clear |
| V E Gould, G Chejfec, K Shah, E Paloyan, A M Lawrenc. Adult nesidiodysplasia. Seminars in diagnostic pathology. vol 1. issue 1. 1988-02-20. PMID:6400629. |
we suggest that the hyperinsulinemic hypoglycemia in these adults was not due to simple quantitative abnormalities in total endocrine cell mass nor to its maldistribution nor to lack of topographic proximity between insulin and somatostatin cells. |
1988-02-20 |
2023-08-12 |
Not clear |
| S W Lambert. A guide to the clinical use of the somatostatin analogue SMS 201-995 (Sandostatin). Acta endocrinologica. Supplementum. vol 286. 1988-02-17. PMID:2892338. |
sms 201-995 (sandostatin) is an octapeptide which differs in its action from native somatostatin in four ways: 1) it inhibits gh hormone secretion in preference to insulin secretion; 2) it can be administered subcutaneously or even orally; 3) it is long-acting (t1/2 after sc administration 113 min), and 4) there is no rebound hypersecretion of hormones when the effect of the analogue lingers off. |
1988-02-17 |
2023-08-11 |
Not clear |
| R Berzins, K R Wieczorek, R V Rajotte, G D Molnar, Y K Tam, J R McGregor, D M Fawcet. Accuracy of C-peptide:insulin molar ratio as a measure of hepatic removal of insulin. Diabetes research and clinical practice. vol 4. issue 1. 1988-01-28. PMID:2891470. |
in anesthetized dogs (n = 6), during electromagnetic hepatic blood flow monitoring, endogenous insulin was suppressed with somatostatin, while equimolar proportions of porcine insulin and simian c-peptide (2.4 and 6.0 pmol/kg.min) were infused during two consecutive 45-min periods. |
1988-01-28 |
2023-08-11 |
Not clear |
| V Leclercq-Meyer, M C Woussen-Colle, C Lalieu, J Marchand, W J Malaiss. Anomeric specificity of glucose-induced somatostatin secretion. Experientia. vol 43. issue 11-12. 1988-01-26. PMID:2891561. |
in isolated perfused rat pancreases, the alpha-anomer of d-glucose is more potent than beta-d-glucose not solely in stimulating insulin release and suppressing glucagon output, but also in causing somatostatin secretion. |
1988-01-26 |
2023-08-11 |
rat |
| M L Brandi, C M Rotella, C Mavilia, F Franceschelli, A Tanini, R Toccafond. Insulin stimulates cell growth of a new strain of differentiated rat thyroid cells. Molecular and cellular endocrinology. vol 54. issue 1. 1988-01-15. PMID:2824250. |
the primary culture was grown in coon's modified ham's f12 medium with 5% calf serum, insulin, hydrocortisone, transferrin, somatostatin, glycyl-l-histidyl-l-lysine and thyrotropin (tsh). |
1988-01-15 |
2023-08-11 |
rat |
| A R Diani, G A Sawada, B A Hannah, K S Jodelis, M A Connell, C L Connell, T J Vidmar, B M Wys. Analysis of pancreatic islet cells and hormone content in the spontaneously diabetic KKAy mouse by morphometry, immunocytochemistry and radioimmunoassay. Virchows Archiv. A, Pathological anatomy and histopathology. vol 412. issue 1. 1988-01-13. PMID:2446417. |
the insulin cells of the diabetic mice were severely degranulated and many of the glucagon, somatostatin and pancreatic polypeptide cells were displaced from the mantle to the core of the islet tissue where the non-insulin cells appeared to lose their continuity. |
1988-01-13 |
2023-08-11 |
mouse |
| A R Diani, G A Sawada, B A Hannah, K S Jodelis, M A Connell, C L Connell, T J Vidmar, B M Wys. Analysis of pancreatic islet cells and hormone content in the spontaneously diabetic KKAy mouse by morphometry, immunocytochemistry and radioimmunoassay. Virchows Archiv. A, Pathological anatomy and histopathology. vol 412. issue 1. 1988-01-13. PMID:2446417. |
the volume and numerical percents of the insulin cells were significantly increased whereas those of the glucagon and somatostatin cells were decreased in the kkay mice. |
1988-01-13 |
2023-08-11 |
mouse |
| A R Diani, G A Sawada, B A Hannah, K S Jodelis, M A Connell, C L Connell, T J Vidmar, B M Wys. Analysis of pancreatic islet cells and hormone content in the spontaneously diabetic KKAy mouse by morphometry, immunocytochemistry and radioimmunoassay. Virchows Archiv. A, Pathological anatomy and histopathology. vol 412. issue 1. 1988-01-13. PMID:2446417. |
pancreatic insulin and somatostatin contents were markedly diminished in the islets of kkay compared with those of c57bl/6 mice. |
1988-01-13 |
2023-08-11 |
mouse |
| E J Verspohl, H P Ammo. Cholecystokinin (CCK8) regulates glucagon, insulin, and somatostatin secretion from isolated rat pancreatic islets: interaction with glucose. Pflugers Archiv : European journal of physiology. vol 410. issue 3. 1988-01-12. PMID:2891102. |
cholecystokinin (cck8) regulates glucagon, insulin, and somatostatin secretion from isolated rat pancreatic islets: interaction with glucose. |
1988-01-12 |
2023-08-11 |
rat |
| E J Verspohl, H P Ammo. Cholecystokinin (CCK8) regulates glucagon, insulin, and somatostatin secretion from isolated rat pancreatic islets: interaction with glucose. Pflugers Archiv : European journal of physiology. vol 410. issue 3. 1988-01-12. PMID:2891102. |
the effect of cck8 on glucagon, insulin and somatostatin release and its interaction with glucose was studied in freshly isolated rat pancreatic islets. |
1988-01-12 |
2023-08-11 |
rat |
| A Secchi, A E Pontiroli, E Bosi, P M Piatti, J L Touraine, L D Monti, A Gelet, J Traeger, J M Dubernard, G Pozz. Effects of arginine and arginine plus somatostatin infusion on insulin release in diabetic patients submitted to pancreas allotransplantation. Diabete & metabolisme. vol 13. issue 4. 1988-01-11. PMID:2890540. |
effects of arginine and arginine plus somatostatin infusion on insulin release in diabetic patients submitted to pancreas allotransplantation. |
1988-01-11 |
2023-08-11 |
human |
| b' M Gutniak, S G Karlander, S Efendi\\xc4\\x8. Glyburide decreases insulin requirement, increases beta-cell response to mixed meal, and does not affect insulin sensitivity: effects of short- and long-term combined treatment in secondary failure to sulfonylurea. Diabetes care. vol 10. issue 5. 1988-01-07. PMID:2890501.' |
the subjects underwent normoglycemic clamp studies and meal tests with determination of insulin, c-peptide, glucagon, somatostatin, and gastric inhibitory polypeptide in plasma. |
1988-01-07 |
2023-08-11 |
human |
| b' M Gutniak, S G Karlander, S Efendi\\xc4\\x8. Glyburide decreases insulin requirement, increases beta-cell response to mixed meal, and does not affect insulin sensitivity: effects of short- and long-term combined treatment in secondary failure to sulfonylurea. Diabetes care. vol 10. issue 5. 1988-01-07. PMID:2890501.' |
glyburide increased basal and meal-but not glucagon-stimulated insulin and c-peptide levels, and also augmented the effect of meals on somatostatin release. |
1988-01-07 |
2023-08-11 |
human |
| R R Rojas-Corona, L Z Chen, P S Mahadevi. Prostatic carcinoma with endocrine features. A report of a neoplasm containing multiple immunoreactive hormonal substances. American journal of clinical pathology. vol 88. issue 6. 1987-12-23. PMID:2891293. |
the tumor contained ultrastructural dense core neuroendocrine granules, and immunoperoxidase staining revealed prostatic acid phosphatase, prostatic-specific antigen, chromogranin, neuron-specific enolase, serotonin, adrenocorticotrophic hormone (acth), somatostatin, parathormone, calcitonin, bombesin, and glucagon but no insulin. |
1987-12-23 |
2023-08-11 |
Not clear |
| C Ariznavarreta, R Fernandez-Durang. Influence of streptozotocin-induced diabetes on the concentration of immunoreactive somatostatin in the retina and peripheral blood of the rat: effect of insulin treatment. The Journal of endocrinology. vol 114. issue 3. 1987-12-15. PMID:2889787. |
influence of streptozotocin-induced diabetes on the concentration of immunoreactive somatostatin in the retina and peripheral blood of the rat: effect of insulin treatment. |
1987-12-15 |
2023-08-11 |
rat |
| Y H Tu, W Y Zh. [Effects of exogenous and endogenous somatostatin on serum insulin concentration in streptozotocin diabetic mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 39. issue 3. 1987-12-15. PMID:2890212. |
[effects of exogenous and endogenous somatostatin on serum insulin concentration in streptozotocin diabetic mice]. |
1987-12-15 |
2023-08-11 |
mouse |
| M Miettinen, S Partanen, O Fräki, E Kivilaaks. Papillary cystic tumor of the pancreas. An analysis of cellular differentiation by electron microscopy and immunohistochemistry. The American journal of surgical pathology. vol 11. issue 11. 1987-12-14. PMID:3674283. |
the tumors were at least focally positive for neuron-specific enolase, and small clusters of polypeptide hormone immunoreactive cells were present in all cases (glucagon 3/3, somatostatin 2/3, insulin 2/3). |
1987-12-14 |
2023-08-11 |
Not clear |
| S Efendić, K Tatemoto, V Mutt, C Quan, D Chang, C G Ostenso. Pancreastatin and islet hormone release. Proceedings of the National Academy of Sciences of the United States of America. vol 84. issue 20. 1987-11-25. PMID:2890162. |
the effect of pancreastatin on the release of insulin, glucagon, and somatostatin was studied in the isolated perfused rat pancreas. |
1987-11-25 |
2023-08-11 |
rat |
| S Efendić, K Tatemoto, V Mutt, C Quan, D Chang, C G Ostenso. Pancreastatin and islet hormone release. Proceedings of the National Academy of Sciences of the United States of America. vol 84. issue 20. 1987-11-25. PMID:2890162. |
as expected, the glucose and the arginine augmented insulin and somatostatin release. |
1987-11-25 |
2023-08-11 |
rat |