Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
B Ahrén, H Mårtensson, A Nobi. Cholecystokinin (CCK)-4 and CCK-8 stimulate islet hormone secretion in vivo in the pig. Pancreas. vol 3. issue 3. 1988-08-08. PMID:2898779. |
we therefore investigated the influences of the c-terminal octapeptide of cck, cck-8 (sulfated form) and of the c-terminal tetrapeptide, cck-4, on the secretion of insulin, glucagon, and somatostatin from the pig pancreas in vivo by infusing each of the two peptides into the superior pancreatic artery. |
1988-08-08 |
2023-08-11 |
Not clear |
B Ahrén, H Mårtensson, A Nobi. Cholecystokinin (CCK)-4 and CCK-8 stimulate islet hormone secretion in vivo in the pig. Pancreas. vol 3. issue 3. 1988-08-08. PMID:2898779. |
we conclude that in pigs, cck-8 and cck-4 both stimulate the secretion of insulin, glucagon, and somatostatin from the pancreas in vivo. |
1988-08-08 |
2023-08-11 |
Not clear |
G Williams, H S Füessl, J M Burrin, E Chilvers, S R Bloo. Postprandial glycaemic effects of a long-acting somatostatin analogue (octreotide) in non-insulin dependent diabetes mellitus. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 20. issue 3. 1988-08-04. PMID:2898427. |
postprandial changes in blood glucose, insulin and glucagon were examined in 7 non-insulin dependent diabetic patients, before and after 3 days' treatment with the somatostatin analogue, octreotide (50 ug injected subcutaneously thricedaily). |
1988-08-04 |
2023-08-11 |
Not clear |
G Williams, H S Füessl, J M Burrin, E Chilvers, S R Bloo. Postprandial glycaemic effects of a long-acting somatostatin analogue (octreotide) in non-insulin dependent diabetes mellitus. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 20. issue 3. 1988-08-04. PMID:2898427. |
animal studies have suggested that octreotide inhibits growth hormone and glucagon secretion much more powerfully than native somatostatin, while relatively sparing insulin secretion. |
1988-08-04 |
2023-08-11 |
Not clear |
M Kollind, U Adamson, P E Lin. Somatostatin reduces posthypoglycemic insulin resistance in insulin-dependent diabetes mellitus. Acta endocrinologica. vol 118. issue 2. 1988-08-04. PMID:2898855. |
somatostatin reduces posthypoglycemic insulin resistance in insulin-dependent diabetes mellitus. |
1988-08-04 |
2023-08-11 |
Not clear |
M Kollind, U Adamson, P E Lin. Somatostatin reduces posthypoglycemic insulin resistance in insulin-dependent diabetes mellitus. Acta endocrinologica. vol 118. issue 2. 1988-08-04. PMID:2898855. |
in order to study whether somatostatin reduces posthypoglycemic insulin resistance, hypoglycemia was induced between 7.00 and 8.00 h by an iv infusion of insulin with and without somatostatin (250 micrograms/h) in 6 male patients with insulin-dependent diabetes mellitus (iddm). |
1988-08-04 |
2023-08-11 |
Not clear |
M Kollind, U Adamson, P E Lin. Somatostatin reduces posthypoglycemic insulin resistance in insulin-dependent diabetes mellitus. Acta endocrinologica. vol 118. issue 2. 1988-08-04. PMID:2898855. |
insulin resistance, as seen following hypoglycemia, was not demonstrable in the study with somatostatin. |
1988-08-04 |
2023-08-11 |
Not clear |
M Kollind, U Adamson, P E Lin. Somatostatin reduces posthypoglycemic insulin resistance in insulin-dependent diabetes mellitus. Acta endocrinologica. vol 118. issue 2. 1988-08-04. PMID:2898855. |
it is concluded that somatostatin reduces insulin resistance following hypoglycemia in patients with iddm. |
1988-08-04 |
2023-08-11 |
Not clear |
E Solcia, C Capella, C Riva, G Rindi, J M Pola. The morphology and neuroendocrine profile of pancreatic epithelial VIPomas and extrapancreatic, VIP-producing, neurogenic tumors. Annals of the New York Academy of Sciences. vol 527. 1988-08-03. PMID:2839087. |
the pancreatic and jejunal tumors showed all structural and secretory patterns of epithelial endocrine tumors, including expression of cytokeratin, neuroendocrine markers like neuron-specific enolase, chromogranins and synaptophysin, peptides like vip, phm, grh, pp, insulin, neurotensin, glucagon, somatostatin and enkephalin, secretory granules, small clear vesicles, peculiar osmiophilic bodies, and occasional formation of tubules or microacini with specialized luminal surfaces. |
1988-08-03 |
2023-08-11 |
Not clear |
D R Owens, J P Vora, J Birtwell, S Luzio, T M Haye. The influence of aprotinin on regional absorption of soluble human insulin. British journal of clinical pharmacology. vol 25. issue 4. 1988-07-29. PMID:2454647. |
the plasma immunoreactive insulin profiles were determined during a 6 h post injection period in subjects receiving concomitantly somatostatin to suppress endogenous insulin secretion. |
1988-07-29 |
2023-08-11 |
human |
S Reddy, N J Bibby, R B Elliot. An immunofluorescent study of insulin-, glucagon-, pancreatic polypeptide- and somatostatin-containing cells in the early ovine fetal pancreas. Quarterly journal of experimental physiology (Cambridge, England). vol 73. issue 2. 1988-07-18. PMID:2898160. |
using antisera to insulin, glucagon, pancreatic polypeptide (pp) and somatostatin, the localization and cellular distribution of the four hormones were investigated in the sheep fetal pancreas of day 40-45 gestation by immunofluorescence. |
1988-07-18 |
2023-08-11 |
Not clear |
S Reddy, N J Bibby, R B Elliot. An immunofluorescent study of insulin-, glucagon-, pancreatic polypeptide- and somatostatin-containing cells in the early ovine fetal pancreas. Quarterly journal of experimental physiology (Cambridge, England). vol 73. issue 2. 1988-07-18. PMID:2898160. |
insulin and glucagon immunoreactive cells were seen in larger numbers compared to fetal pp and somatostatin cells and were located either in the developing islets or as single scattered cells in the epithelium of the embryonic ductules. |
1988-07-18 |
2023-08-11 |
Not clear |
S Reddy, N J Bibby, R B Elliot. An immunofluorescent study of insulin-, glucagon-, pancreatic polypeptide- and somatostatin-containing cells in the early ovine fetal pancreas. Quarterly journal of experimental physiology (Cambridge, England). vol 73. issue 2. 1988-07-18. PMID:2898160. |
in the pancreas of day 40-45 fetuses pp cells were less numerous than glucagon and insulin cells while somatostatin cells were seen rarely. |
1988-07-18 |
2023-08-11 |
Not clear |
S Reddy, N J Bibby, R B Elliot. An immunofluorescent study of insulin-, glucagon-, pancreatic polypeptide- and somatostatin-containing cells in the early ovine fetal pancreas. Quarterly journal of experimental physiology (Cambridge, England). vol 73. issue 2. 1988-07-18. PMID:2898160. |
our studies demonstrate the presence of insulin, glucagon, pp and somatostatin within distinct cell types in the early sheep fetal pancreas. |
1988-07-18 |
2023-08-11 |
Not clear |
D C Shen, S W Kuo, L R Shian, M T Fuh, D A Wu, Y D Chen, G M Reave. Insulin secretion and insulin action in Taiwanese with type 2 diabetes. Diabetes research and clinical practice. vol 4. issue 4. 1988-06-30. PMID:2897274. |
insulin action was estimated by determination of the steady-state plasma insulin (sspi) and glucose (sspg) concentrations during the last 60 min of a continuous 180-min intravenous infusion of somatostatin, crystalline insulin, and glucose. |
1988-06-30 |
2023-08-11 |
human |
G R Greenberg, T J McDonal. Effect of galanin and vagal integrity on insulin release in dogs. Pancreas. vol 3. issue 2. 1988-06-27. PMID:2453871. |
thus, the inhibition of plasma insulin responses to glucose by galanin is mediated by a nonvagal, noncholinergic mechanism and is independent of changes in either plasma pancreatic glucagon or somatostatin levels. |
1988-06-27 |
2023-08-11 |
Not clear |
D J Garry, N M Appel, M G Garry, R L Sorenso. Cellular and subcellular immunolocalization of L-glutamate decarboxylase in rat pancreatic islets. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 36. issue 6. 1988-06-23. PMID:2896676. |
at this level of resolution, immunofluorescent gad was observed to be co-localized with immunofluorescent insulin in the islet b-cells and absent in both the a-cells, which contained glucagon, and the d-cells, which contained somatostatin. |
1988-06-23 |
2023-08-11 |
rat |
R Drut, R M Dru. An immunohistochemical study of islet cells with macronuclei in infancy. Pediatric pathology. vol 7. issue 5-6. 1988-06-20. PMID:3329722. |
we report an immunohistochemical and semiquantitative study of hypertrophic islet cells in 14 infants with neonatal hypoglycemia (10 with documented persistent neonatal hypoglycemia and 4 with probable persistent neonatal hypoglycemia) and 6 infants born to diabetic mothers (idm), using an indirect immunoperoxidase methods for the demonstration of insulin, somatostatin, and glucagon. |
1988-06-20 |
2023-08-11 |
Not clear |
R Drut, R M Dru. An immunohistochemical study of islet cells with macronuclei in infancy. Pediatric pathology. vol 7. issue 5-6. 1988-06-20. PMID:3329722. |
polyploid cells were positive for insulin and somatostatin but negative for glucagon; insulin-positive cells outnumbered somatostatin-positive cells in both groups. |
1988-06-20 |
2023-08-11 |
Not clear |
L T Ho, H F Pu, W J Sheu, W C Wang, P S Wan. Inhibition of somatostatin on glucose-induced release of gastric inhibitory polypeptide in rats. The Chinese journal of physiology. vol 30. issue 2. 1988-06-16. PMID:2896583. |
the effect of somatostatin on glucoseinduced secretion of insulin and gastric inhibitory polypeptide (gip) in rats was examined. |
1988-06-16 |
2023-08-11 |
rat |