| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B S Baliga, S M Borowit. Effects of growth and differentiation inducing factors on protein kinase-C of cultured intestinal crypt cells. Biochemical and biophysical research communications. vol 154. issue 1. 1988-08-18. PMID:3395331. |
to assess the role of protein kinase-c (pk-c) in the growth and differentiation of small intestinal enterocytes, iec-6 cells (a cell line derived from the crypts of rat small intestine) were incubated with factors known to induce growth (insulin, epidermal growth factor, gastrin, somatostatin and transferrin) or differentiation (transforming growth factor-beta, retinoic acid and phorbol 12-myristate 13-acetate (pma)). |
1988-08-18 |
2023-08-11 |
rat |
| L Monge, R A Silvestre, P Miralles, E Peiró, M L Villanueva, J Marc. In vitro effects of BAY K 8644, a dihydropyridine derivative with hypoglycaemic properties, on hepatic glucose production and pancreatic hormone secretion. Biochemical pharmacology. vol 37. issue 15. 1988-08-17. PMID:2456069. |
in the perfused rat pancreas, bay k 8644 markedly stimulated insulin release without modifying glucagon or somatostatin output. |
1988-08-17 |
2023-08-11 |
rat |
| E Vara, J Tamarit-Rodrígue. Islet secretion of immunoreactive thyrotropin-releasing hormone and the 'paracrine-like' effects of its exogenous administration. Acta endocrinologica. vol 118. issue 3. 1988-08-17. PMID:2899370. |
in order to know more about the secretory pattern of islet trh in response to glucose and its possible physiological relevance, the release of this hormone as well as that of insulin, glucagon, and somatostatin was radioimmunologically measured. |
1988-08-17 |
2023-08-11 |
rat |
| E Vara, J Tamarit-Rodrígue. Islet secretion of immunoreactive thyrotropin-releasing hormone and the 'paracrine-like' effects of its exogenous administration. Acta endocrinologica. vol 118. issue 3. 1988-08-17. PMID:2899370. |
whereas the secretion of immunoreactive insulin and somatostatin by incubated rat islets is known to be dose-dependently stimulated by glucose, that of glucagon and trh was inhibited by glucose. |
1988-08-17 |
2023-08-11 |
rat |
| E Vara, J Tamarit-Rodrígue. Islet secretion of immunoreactive thyrotropin-releasing hormone and the 'paracrine-like' effects of its exogenous administration. Acta endocrinologica. vol 118. issue 3. 1988-08-17. PMID:2899370. |
it inhibited the insulin response to glucose and blocked that of glucagon, whereas it enhanced glucose-induced stimulation of somatostatin. |
1988-08-17 |
2023-08-11 |
rat |
| E Vara, J Tamarit-Rodrígue. Islet secretion of immunoreactive thyrotropin-releasing hormone and the 'paracrine-like' effects of its exogenous administration. Acta endocrinologica. vol 118. issue 3. 1988-08-17. PMID:2899370. |
these results are suggestive of a possible paracrine inhibitory role of islet trh, either directly exerted on the secretion of insulin and glucagon or partially mediated through the stimulation of somatostatin release. |
1988-08-17 |
2023-08-11 |
rat |
| D C Wilson, D J Carson, R J Quin. Long-term use of somatostatin analogue SMS 201-995 in the treatment of hypoglycaemia due to nesidioblastosis. Acta paediatrica Scandinavica. vol 77. issue 3. 1988-08-11. PMID:2898862. |
subcutaneous somatostatin analogue (sms 201-995) was shown to increase the blood concentrations of glucose and b-hydroxybutyrate while lowering serum insulin levels. |
1988-08-11 |
2023-08-11 |
Not clear |
| J H Youson, W M Elliott, R J Beamish, D W Wan. A comparison of endocrine pancreatic tissue in adults of four species of lampreys in British Columbia: a morphological and immunohistochemical study. General and comparative endocrinology. vol 70. issue 2. 1988-08-11. PMID:3290047. |
histological techniques and immunohistochemistry with antisera against insulin and somatostatin were used in a study of the identification and the distribution of endocrine pancreatic tissue in adults of four species of lampreys in british columbia. |
1988-08-11 |
2023-08-11 |
Not clear |
| J H Youson, W M Elliott, R J Beamish, D W Wan. A comparison of endocrine pancreatic tissue in adults of four species of lampreys in British Columbia: a morphological and immunohistochemical study. General and comparative endocrinology. vol 70. issue 2. 1988-08-11. PMID:3290047. |
marifuga is composed of cells which are immunoreactive to either insulin or somatostatin antisera. |
1988-08-11 |
2023-08-11 |
Not clear |
| J A Ramsay, K Kovacs, S L Asa, M J Pike, M O Thorne. Reversible sellar enlargement due to growth hormone-releasing hormone production by pancreatic endocrine tumors in a acromegalic patient with multiple endocrine neoplasia type I syndrome. Cancer. vol 62. issue 2. 1988-08-10. PMID:2898285. |
immunoreactivity for insulin was present in the larger tumor; the smaller tumor contained glucagon, gastrin, somatostatin, and pancreatic polypeptide. |
1988-08-10 |
2023-08-11 |
Not clear |
| G Chejfec, S Falkmer, U Askensten, L Grimelius, V E Goul. Neuroendocrine tumors of the gastrointestinal tract. Pathology, research and practice. vol 183. issue 2. 1988-08-09. PMID:3290866. |
foregut carcinoids usually contain serotonin, gastrin, and somatostatin, midgut carcinoids often only serotonin and tachykinins, whereas the hindgut carcinoids as a rule are multihormonal with a wide spectrum of hormonal peptides, including even insulin. |
1988-08-09 |
2023-08-11 |
rat |
| M K Müller, B Kessel, T Hütt, R Kath, P Layer, H Goebel. Effects of somatostatin-14 on gastric and pancreatic responses to hormonal and neural stimulation using an isolated perfused rat stomach and pancreas preparation. Pancreas. vol 3. issue 3. 1988-08-08. PMID:2455292. |
in contrast, somatostatin significantly inhibited glucose-dependent insulin and gastrin secretion, either basal or stimulated by vagal activity or acetylcholine. |
1988-08-08 |
2023-08-11 |
rat |
| M K Müller, B Kessel, T Hütt, R Kath, P Layer, H Goebel. Effects of somatostatin-14 on gastric and pancreatic responses to hormonal and neural stimulation using an isolated perfused rat stomach and pancreas preparation. Pancreas. vol 3. issue 3. 1988-08-08. PMID:2455292. |
acetylcholine-induced gastrin secretion was more sensitive to inhibition by somatostatin than insulin. |
1988-08-08 |
2023-08-11 |
rat |
| B Ahrén, H Mårtensson, A Nobi. Cholecystokinin (CCK)-4 and CCK-8 stimulate islet hormone secretion in vivo in the pig. Pancreas. vol 3. issue 3. 1988-08-08. PMID:2898779. |
we therefore investigated the influences of the c-terminal octapeptide of cck, cck-8 (sulfated form) and of the c-terminal tetrapeptide, cck-4, on the secretion of insulin, glucagon, and somatostatin from the pig pancreas in vivo by infusing each of the two peptides into the superior pancreatic artery. |
1988-08-08 |
2023-08-11 |
Not clear |
| B Ahrén, H Mårtensson, A Nobi. Cholecystokinin (CCK)-4 and CCK-8 stimulate islet hormone secretion in vivo in the pig. Pancreas. vol 3. issue 3. 1988-08-08. PMID:2898779. |
we conclude that in pigs, cck-8 and cck-4 both stimulate the secretion of insulin, glucagon, and somatostatin from the pancreas in vivo. |
1988-08-08 |
2023-08-11 |
Not clear |
| G Williams, H S Füessl, J M Burrin, E Chilvers, S R Bloo. Postprandial glycaemic effects of a long-acting somatostatin analogue (octreotide) in non-insulin dependent diabetes mellitus. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 20. issue 3. 1988-08-04. PMID:2898427. |
postprandial changes in blood glucose, insulin and glucagon were examined in 7 non-insulin dependent diabetic patients, before and after 3 days' treatment with the somatostatin analogue, octreotide (50 ug injected subcutaneously thricedaily). |
1988-08-04 |
2023-08-11 |
Not clear |
| G Williams, H S Füessl, J M Burrin, E Chilvers, S R Bloo. Postprandial glycaemic effects of a long-acting somatostatin analogue (octreotide) in non-insulin dependent diabetes mellitus. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 20. issue 3. 1988-08-04. PMID:2898427. |
animal studies have suggested that octreotide inhibits growth hormone and glucagon secretion much more powerfully than native somatostatin, while relatively sparing insulin secretion. |
1988-08-04 |
2023-08-11 |
Not clear |
| M Kollind, U Adamson, P E Lin. Somatostatin reduces posthypoglycemic insulin resistance in insulin-dependent diabetes mellitus. Acta endocrinologica. vol 118. issue 2. 1988-08-04. PMID:2898855. |
somatostatin reduces posthypoglycemic insulin resistance in insulin-dependent diabetes mellitus. |
1988-08-04 |
2023-08-11 |
Not clear |
| M Kollind, U Adamson, P E Lin. Somatostatin reduces posthypoglycemic insulin resistance in insulin-dependent diabetes mellitus. Acta endocrinologica. vol 118. issue 2. 1988-08-04. PMID:2898855. |
in order to study whether somatostatin reduces posthypoglycemic insulin resistance, hypoglycemia was induced between 7.00 and 8.00 h by an iv infusion of insulin with and without somatostatin (250 micrograms/h) in 6 male patients with insulin-dependent diabetes mellitus (iddm). |
1988-08-04 |
2023-08-11 |
Not clear |
| M Kollind, U Adamson, P E Lin. Somatostatin reduces posthypoglycemic insulin resistance in insulin-dependent diabetes mellitus. Acta endocrinologica. vol 118. issue 2. 1988-08-04. PMID:2898855. |
insulin resistance, as seen following hypoglycemia, was not demonstrable in the study with somatostatin. |
1988-08-04 |
2023-08-11 |
Not clear |