| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Kusunoki, T Yamamura, S Ichii, S Fujita, T Nakai, J Utsunomiy. The effects of sodium valproate on plasma somatostatin and insulin in humans. The Journal of clinical endocrinology and metabolism. vol 67. issue 5. 1988-12-01. PMID:2903170. |
these results suggest that endogenous gaba may play some role in the release of somatostatin, but not in the release of insulin. |
1988-12-01 |
2023-08-11 |
human |
| G C Raju, Y S Le. Gastrointestinal carcinoid tumours: histological, histochemical and immunohistochemical study. Annals of the Academy of Medicine, Singapore. vol 17. issue 1. 1988-11-30. PMID:2461142. |
immunoreactivity for somatostatin was seen in 8 cases, glucagon in three, and corticotrophin, insulin and gastrin in one case each. |
1988-11-30 |
2023-08-11 |
Not clear |
| R Shob. Changes of plasma insulin glucagon and somatostatin in portal blood and morphological changes of islets of Langerhans after hepatectomy in dogs. Gastroenterologia Japonica. vol 23. issue 4. 1988-11-29. PMID:2903109. |
changes of plasma insulin glucagon and somatostatin in portal blood and morphological changes of islets of langerhans after hepatectomy in dogs. |
1988-11-29 |
2023-08-11 |
Not clear |
| J M Conlon, M Reinecke, M C Thorndyke, S Falkme. Insulin and other islet hormones (somatostatin, glucagon and PP) in the neuroendocrine system of some lower vertebrates and that of invertebrates--a minireview. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 20. issue 7. 1988-11-22. PMID:2901999. |
insulin and other islet hormones (somatostatin, glucagon and pp) in the neuroendocrine system of some lower vertebrates and that of invertebrates--a minireview. |
1988-11-22 |
2023-08-11 |
Not clear |
| J M Conlon, M Reinecke, M C Thorndyke, S Falkme. Insulin and other islet hormones (somatostatin, glucagon and PP) in the neuroendocrine system of some lower vertebrates and that of invertebrates--a minireview. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 20. issue 7. 1988-11-22. PMID:2901999. |
onto- and phylogenetical studies of the evolution of cells, producing regulatory peptides, belonging to the "hormone families" of insulin, somatostatin, glucagon, and pp (the pancreatic polypeptide), have shown that the islets of langerhans in vertebrates form a substantial part of the large neuroendocrine system (nes). |
1988-11-22 |
2023-08-11 |
Not clear |
| J M Conlon, M Reinecke, M C Thorndyke, S Falkme. Insulin and other islet hormones (somatostatin, glucagon and PP) in the neuroendocrine system of some lower vertebrates and that of invertebrates--a minireview. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 20. issue 7. 1988-11-22. PMID:2901999. |
it is a two-hormone organ with insulin and somatostatin cells only. |
1988-11-22 |
2023-08-11 |
Not clear |
| B Ahrén, R C Veith, G J Taborsk. The effects of epinephrine on islet hormone secretion in the dog. International journal of pancreatology : official journal of the International Association of Pancreatology. vol 3. issue 5. 1988-11-22. PMID:2902147. |
we investigated the direct effects of physiological levels of epinephrine on the basal and arginine-stimulated secretion of insulin, glucagon, and somatostatin from the in situ pancreas in halothane-anaesthetized dogs. |
1988-11-22 |
2023-08-11 |
dog |
| B Ahrén, R C Veith, G J Taborsk. The effects of epinephrine on islet hormone secretion in the dog. International journal of pancreatology : official journal of the International Association of Pancreatology. vol 3. issue 5. 1988-11-22. PMID:2902147. |
the acute insulin response (air) to 2.5 g of arginine during this infusion of epinephrine was significantly higher (p less than 0.05) than in controls as were the acute glucagon response (agr) (p less than 0.05) and the acute somatostatin response (aslir) (p less than 0.05). |
1988-11-22 |
2023-08-11 |
dog |
| B Ahrén, R C Veith, G J Taborsk. The effects of epinephrine on islet hormone secretion in the dog. International journal of pancreatology : official journal of the International Association of Pancreatology. vol 3. issue 5. 1988-11-22. PMID:2902147. |
at stress levels of 900-1000 pg/ml, both insulin and somatostatin secretion are stimulated; only at near pharmacologic, or extreme stress levels, does epinephrine produce net inhibition. |
1988-11-22 |
2023-08-11 |
dog |
| R Candrina, G Giustin. Effect of a new long-acting somatostatin analogue (SMS 201-995) on glycemic and hormonal profiles in insulin-treated type II diabetic patients. Journal of endocrinological investigation. vol 11. issue 7. 1988-11-21. PMID:3049768. |
five type ii diabetic patients were studied after secondary failure of oral agents, with and without the addition of the new long-acting somatostatin analogue sms 201-995 to an intermediate-acting insulin regimen. |
1988-11-21 |
2023-08-11 |
Not clear |
| J Chen, S I Baithun, D J Pollock, C L Berr. Argyrophilic and hormone immunoreactive cells in normal and hyperplastic pancreatic ducts and exocrine pancreatic carcinoma. Virchows Archiv. A, Pathological anatomy and histopathology. vol 413. issue 5. 1988-11-18. PMID:2459841. |
using four antisera (against insulin, glucagon, somatostatin and gastrin), insulin, glucagon and somatostatin cells were identified in 2.65%, 0.001% and 1.2% of normal ducts, and 7.5%, 2.4% and 4.6% of ducts with hyperplastic epithelium respectively and were also greatly increased in numbers in the latter group. |
1988-11-18 |
2023-08-11 |
Not clear |
| J Chen, S I Baithun, D J Pollock, C L Berr. Argyrophilic and hormone immunoreactive cells in normal and hyperplastic pancreatic ducts and exocrine pancreatic carcinoma. Virchows Archiv. A, Pathological anatomy and histopathology. vol 413. issue 5. 1988-11-18. PMID:2459841. |
cells reactive for insulin were found in 7/15 cases; glucagon in 6/15 cases; somatostatin in 5/15 cases and gastrin in 2/15 cases. |
1988-11-18 |
2023-08-11 |
Not clear |
| E Martens, R Zick, H J Mitzkat, A von zur Mühlen, M J Mülle. Assessment of insulin action in man: role of hyperglycemia. Acta endocrinologica. vol 119. issue 2. 1988-11-15. PMID:2902721. |
the effect of hyperglycemia on insulin-induced glucose metabolism (m) was investigated in healthy subjects using sequential clamp protocols at constant insulin + somatostatin infusions and varying plasma glucose. |
1988-11-15 |
2023-08-11 |
human |
| L C Pan. Pancreatic heterotopia: a reappraisal and clinicopathologic analysis of 32 cases. Southern medical journal. vol 81. issue 10. 1988-11-10. PMID:3051429. |
mallory's phosphotungstic acid-hematoxylin stain was used to demonstrate zymogen granules in the acinar cells, and insulin, glucagon, and somatostatin were demonstrated with the horseradish peroxidase-antihorseradish peroxidase immunocytochemical staining technique; islets of langerhans were also identified. |
1988-11-10 |
2023-08-11 |
Not clear |
| A C Powers, J Philippe, H Hermann, J F Habene. Sodium butyrate increases glucagon and insulin gene expression by recruiting immunocytochemically negative cells to produce hormone. Diabetes. vol 37. issue 10. 1988-10-27. PMID:2843409. |
using antisera to glucagon, insulin, and somatostatin, we found that less than 15% of the cells in any of these three islet cell lines contained immunopositive cells. |
1988-10-27 |
2023-08-11 |
rat |
| L M Karabatas, M Arata, L Anaya, J C Cresto, O H Pivetta, J C Basab. First phase of insulin secretion stimulated by glucose plus theophylline and inhibitory effect of somatostatin in genetically diabetic mice (C57BL/KsJ-mdb). Diabetologia. vol 31. issue 6. 1988-10-27. PMID:2901377. |
first phase of insulin secretion stimulated by glucose plus theophylline and inhibitory effect of somatostatin in genetically diabetic mice (c57bl/ksj-mdb). |
1988-10-27 |
2023-08-11 |
mouse |
| L M Karabatas, M Arata, L Anaya, J C Cresto, O H Pivetta, J C Basab. First phase of insulin secretion stimulated by glucose plus theophylline and inhibitory effect of somatostatin in genetically diabetic mice (C57BL/KsJ-mdb). Diabetologia. vol 31. issue 6. 1988-10-27. PMID:2901377. |
in a previous study in c57bl/ksj mdb/mdb mice aged 4 to 12 days we observed a diminished first phase of glucose-induced insulin secretion in vitro, and alterations in the inhibitory effect of somatostatin on insulin secretion. |
1988-10-27 |
2023-08-11 |
mouse |
| L M Karabatas, M Arata, L Anaya, J C Cresto, O H Pivetta, J C Basab. First phase of insulin secretion stimulated by glucose plus theophylline and inhibitory effect of somatostatin in genetically diabetic mice (C57BL/KsJ-mdb). Diabetologia. vol 31. issue 6. 1988-10-27. PMID:2901377. |
this study explores, using perifused pancreatic slices, whether the reduced b-cell responsiveness to somatostatin in mdb/mdb mice can be overcome upon induction of a biphasic insulin release by using theophylline. |
1988-10-27 |
2023-08-11 |
mouse |
| L M Karabatas, M Arata, L Anaya, J C Cresto, O H Pivetta, J C Basab. First phase of insulin secretion stimulated by glucose plus theophylline and inhibitory effect of somatostatin in genetically diabetic mice (C57BL/KsJ-mdb). Diabetologia. vol 31. issue 6. 1988-10-27. PMID:2901377. |
under these conditions our results show: (1) in mdb/mdb mice aged 4 to 6 days, the restoration of the first peak of insulin secretion overcomes the reduced b-cell sensitivity to somatostatin; and (2) in mdb/mdb mice aged 7 to 12 days, the addition of theophylline only causes a partial restoration of b-cell responsiveness to somatostatin, suggesting that other mechanisms could be involved in the progressive impairement of b-cell sensitivity to somatostatin inhibitory effect. |
1988-10-27 |
2023-08-11 |
mouse |
| H H von Dorsche, K Fält, H J Hahn, H Reihe. [Immunocytochemical studies of the development of basal cell types of human islet organs]. Acta histochemica. Supplementband. vol 35. 1988-10-27. PMID:2901775. |
the detection of the 4 islet hormones insulin, glucagon, somatostatin and pp ist carried out in pap-technique. |
1988-10-27 |
2023-08-11 |
human |