| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T P Shankar, S S Solomon, W C Duckworth, T Jerkins, R S Iyer, M A Boba. Growth hormone and carbohydrate intolerance in cirrhosis. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 20. issue 9. 1989-01-13. PMID:3058569. |
glucose tolerance tests (gtt), intravenous insulin tolerance tests (ivitt), arginine stimulation tests (ast) and glucose clamp studies before and during gh suppression with somatostatin were performed in a group of patients with alcohol-induced liver cirrhosis. |
1989-01-13 |
2023-08-11 |
human |
| K Geise. Special pharmacology of the new sulfonylurea glimepiride. Arzneimittel-Forschung. vol 38. issue 8. 1989-01-03. PMID:2904269. |
in the isolated rat pancreas perfused with glucose-free medium, hb 419 released glucagon beside insulin and somatostatin. |
1989-01-03 |
2023-08-11 |
rat |
| K Geise. Special pharmacology of the new sulfonylurea glimepiride. Arzneimittel-Forschung. vol 38. issue 8. 1989-01-03. PMID:2904269. |
the threshold concentration for the glucagon secretion was lower as those for the insulin and somatostatin release. |
1989-01-03 |
2023-08-11 |
rat |
| E Samols, J I Stagne. Intra-islet regulation. The American journal of medicine. vol 85. issue 5A. 1988-12-28. PMID:2461657. |
anterograde infusion of insulin antibody increased glucagon and somatostatin secretion (p less than 0.0005), whereas retrograde insulin antibody infusion was without effect. |
1988-12-28 |
2023-08-11 |
rat |
| E Samols, J I Stagne. Intra-islet regulation. The American journal of medicine. vol 85. issue 5A. 1988-12-28. PMID:2461657. |
anterograde infusion of somatostatin antibody had no effect upon insulin or glucagon secretion. |
1988-12-28 |
2023-08-11 |
rat |
| E Samols, J I Stagne. Intra-islet regulation. The American journal of medicine. vol 85. issue 5A. 1988-12-28. PMID:2461657. |
in contrast, retrograde infusion of somatostatin antibody increased both insulin and glucagon secretion (p less than 0.0005). |
1988-12-28 |
2023-08-11 |
rat |
| E Samols, J I Stagne. Intra-islet regulation. The American journal of medicine. vol 85. issue 5A. 1988-12-28. PMID:2461657. |
in comparison, anterograde infusion of antiglucagon antibody decreased somatostatin secretion without influencing insulin, whereas retrograde antiglucagon antibody infusion decreased insulin without changing somatostatin secretion. |
1988-12-28 |
2023-08-11 |
rat |
| B A Swinburn, M L Yeong, M R Lane, G I Nicholson, I M Holdawa. Neurofibromatosis associated with somatostatinoma: a report of two patients. Clinical endocrinology. vol 28. issue 4. 1988-12-28. PMID:2903805. |
the tumour was diagnosed preoperatively and metabolic studies demonstrated mild diabetes mellitus apparently due to suppression of insulin secretion by somatostatin, since oral glucose tolerance returned to normal post-operatively despite hemipancreatectomy. |
1988-12-28 |
2023-08-11 |
Not clear |
| J Philippe, A C Powers, S Mojsov, D J Drucker, R Comi, J F Habene. Expression of peptide hormone genes in human islet cell tumors. Diabetes. vol 37. issue 12. 1988-12-27. PMID:2903836. |
the embryogenesis of the pancreas suggests the existence of a common stem cell progenitor of the four islet cell types (insulin, glucagon, somatostatin, and pancreatic polypeptide). |
1988-12-27 |
2023-08-11 |
human |
| J Philippe, A C Powers, S Mojsov, D J Drucker, R Comi, J F Habene. Expression of peptide hormone genes in human islet cell tumors. Diabetes. vol 37. issue 12. 1988-12-27. PMID:2903836. |
by analyses of rna transcripts and immunoreactive peptides in four human insulinomas and one glucagonoma, we found that the insulin, somatostatin, and glucagon genes were coexpressed in all tumors. |
1988-12-27 |
2023-08-11 |
human |
| J I Stagner, E Samols, S Bonner-Wei. beta----alpha----delta pancreatic islet cellular perfusion in dogs. Diabetes. vol 37. issue 12. 1988-12-27. PMID:2903837. |
anterograde (arterial) perfusion and retrograde (reversed or venous) perfusion of a segment of isolated dog pancreas with potent insulin antibodies yielded results similar to those found in the rat pancreas (anterograde, 158 +/- 44% increase in glucagon and 65 +/- 20% increase in somatostatin; retrograde, no change in glucagon or somatostatin). |
1988-12-27 |
2023-08-11 |
rat |
| J I Stagner, E Samols, S Bonner-Wei. beta----alpha----delta pancreatic islet cellular perfusion in dogs. Diabetes. vol 37. issue 12. 1988-12-27. PMID:2903837. |
anterograde infusion of glucagon antibody (no change in insulin, -33.5 +/- 3% decrease in somatostatin) or somatostatin antibody (no change in insulin or glucagon) also yielded the same results as in the rat pancreas. |
1988-12-27 |
2023-08-11 |
rat |
| J I Stagner, E Samols, S Bonner-Wei. beta----alpha----delta pancreatic islet cellular perfusion in dogs. Diabetes. vol 37. issue 12. 1988-12-27. PMID:2903837. |
anterograde infusion of 500 pg/ml glucagon caused a larger increase in insulin secretion (245 +/- 10%) than retrograde infusion (45 +/- 4%), whereas somatostatin was stimulated more retrogradely (339 +/- 17%) than anterogradely (121 +/- 9%). |
1988-12-27 |
2023-08-11 |
rat |
| J I Stagner, E Samols, S Bonner-Wei. beta----alpha----delta pancreatic islet cellular perfusion in dogs. Diabetes. vol 37. issue 12. 1988-12-27. PMID:2903837. |
anterograde infusion of somatostatin produced a larger decrease in insulin and glucagon than did retrograde perfusion (p less than .0001 for both comparisons). |
1988-12-27 |
2023-08-11 |
rat |
| J I Stagner, E Samols, S Bonner-Wei. beta----alpha----delta pancreatic islet cellular perfusion in dogs. Diabetes. vol 37. issue 12. 1988-12-27. PMID:2903837. |
the results from the infusion of exogenous hormones suggest that the sensitivity of the alpha-, beta-, and delta-cells to insulin, glucagon, and somatostatin is determined by the beta----alpha----delta order of perfusion. |
1988-12-27 |
2023-08-11 |
rat |
| T Tomita, J Rhodes, J Falscroft, V Doull, J R Kimmel, H G Polloc. Endocrine pancreas in the rat model of exocrine pancreatic insufficiency. Pancreas. vol 3. issue 5. 1988-12-22. PMID:3054870. |
in zein-injected rats, the total pancreatic content of insulin, glucagon, pp, and somatostatin was reduced to 80, 70, 40, and 20%, respectively, of the corresponding controls. |
1988-12-22 |
2023-08-11 |
rat |
| E A Woltering, E J Mozell, T M O'Dorisio, W S Fletcher, B How. Suppression of primary and secondary peptides with somatostatin analog in the therapy of functional endocrine tumors. Surgery, gynecology & obstetrics. vol 167. issue 6. 1988-12-21. PMID:2460958. |
during provocation test, the levels of the primary peptides insulin and c-peptide (nesidioblastosis and insulinoma), gastrin (gastrinoma), glucagon (glucagonoma) and the secondary peptides calcitonin, gastrointestinal peptide, gastrin releasing peptide, motilin, neurotensin, pancreatic polypeptide, somatostatin, substance-p and vasoactive intestinal peptide were obtained at predetermined intervals and quantitated by radioimmunoassay. |
1988-12-21 |
2023-08-11 |
Not clear |
| M Kollin. Studies on posthypoglycemic insulin resistance in insulin-dependent diabetes mellitus. Acta medica Scandinavica. Supplementum. vol 727. 1988-12-16. PMID:2903616. |
insulin resistance was determined by a constant rate intravenous infusion of somatostatin, insulin and glucose. |
1988-12-16 |
2023-08-11 |
Not clear |
| M Kollin. Studies on posthypoglycemic insulin resistance in insulin-dependent diabetes mellitus. Acta medica Scandinavica. Supplementum. vol 727. 1988-12-16. PMID:2903616. |
these studies therefore indicate that the gh suppressing hormone somatostatin may be of clinical value as an adjunct to insulin in the treatment of patients with insulin-dependent diabetes mellitus and labile blood glucose control. |
1988-12-16 |
2023-08-11 |
Not clear |
| M Kusunoki, T Yamamura, S Ichii, S Fujita, T Nakai, J Utsunomiy. The effects of sodium valproate on plasma somatostatin and insulin in humans. The Journal of clinical endocrinology and metabolism. vol 67. issue 5. 1988-12-01. PMID:2903170. |
the effects of sodium valproate on plasma somatostatin and insulin in humans. |
1988-12-01 |
2023-08-11 |
human |