| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D R Hoelzer, G P Dalsky, N S Schwartz, W E Clutter, S D Shah, J O Holloszy, P E Crye. Epinephrine is not critical to prevention of hypoglycemia during exercise in humans. The American journal of physiology. vol 251. issue 1 Pt 1. 1986-08-08. PMID:3524257. |
we documented stability of plasma glucose concentrations and glucose production and utilization rates, and levels of other metabolic substrates and regulatory factors, during the islet clamp (somatostatin infusion with glucagon and insulin replacement) in the absence of an intervention in five normal humans and further applied this technique to the study of glucoregulation during moderate exercise. |
1986-08-08 |
2023-08-11 |
Not clear |
| K Ejiri, H Taniguchi, K Ishihara, Y Hirose, K Terashi, K Murakami, Y Imamura, S Bab. Effects of tris(hydroxymethyl)aminomethane on biosynthesis and release of insulin in the pancreatic Langerhans islets. Diabetes research and clinical practice. vol 1. issue 2. 1986-08-07. PMID:2873007. |
this study was designed to assess the effect of tris on insulin, glucagon and somatostatin release and insulin synthesis in pancreatic b cells by using isolated rat pancreatic islets. |
1986-08-07 |
2023-08-11 |
rat |
| K Ejiri, H Taniguchi, K Ishihara, Y Hirose, K Terashi, K Murakami, Y Imamura, S Bab. Effects of tris(hydroxymethyl)aminomethane on biosynthesis and release of insulin in the pancreatic Langerhans islets. Diabetes research and clinical practice. vol 1. issue 2. 1986-08-07. PMID:2873007. |
tris suppressed glucose-induced insulin release, whereas it did not affect the glucagon and somatostatin release. |
1986-08-07 |
2023-08-11 |
rat |
| R R Wolfe, J H Sha. Effect of epinephrine infusion and adrenergic blockade on glucose oxidation in conscious dogs. Metabolism: clinical and experimental. vol 35. issue 7. 1986-08-07. PMID:3523120. |
in all groups, insulin and glucagon concentrations were held constant throughout by the inhibition of their secretion with somatostatin and intraportal replacement at basal rates. |
1986-08-07 |
2023-08-11 |
Not clear |
| K E Steiner, S M Mouton, P E Williams, W W Lacy, A D Cherringto. Relative importance of first- and second-phase insulin secretion in glucose homeostasis in conscious dog. II. Effects on gluconeogenesis. Diabetes. vol 35. issue 7. 1986-07-30. PMID:3522319. |
in our study the ability of each component of insulin release to counter the effects of the glucagon on gluconeogenesis and alanine metabolism was assessed by mimicking first- and/or second-phase insulin release with infusions of somatostatin and intraportal insulin. |
1986-07-30 |
2023-08-11 |
dog |
| I Gottesman, J Tobert, R Vandlen, J Geric. Efficacy, pharmacokinetics and tolerability of a somatostatin analogue (L-363,586) in insulin-dependent diabetes mellitus. Life sciences. vol 38. issue 24. 1986-07-23. PMID:2872569. |
we conclude that l-363,586 is a long-acting and potent analogue of somatostatin, which has the potential for use as an adjunct to insulin in the treatment of diabetes mellitus. |
1986-07-23 |
2023-08-11 |
human |
| F W Abdul-Karim, B B Dahms, M E Velasco, H M Rodma. Islets of Langerhans in adolescents and adults with cystic fibrosis. A quantitative study. Archives of pathology & laboratory medicine. vol 110. issue 7. 1986-07-22. PMID:2872872. |
the islets of langerhans were stained with immunoperoxidase for insulin, glucagon, and somatostatin. |
1986-07-22 |
2023-08-11 |
Not clear |
| K Kovacs, E Horvath, S L Asa, D Murray, W Singer, S S Redd. Microscopic peliosis of pancreatic islets in a woman with MEN-1 syndrome. Archives of pathology & laboratory medicine. vol 110. issue 7. 1986-07-22. PMID:2872873. |
in addition to microscopic peliosis, the pancreas contained multiple endocrine tumors producing insulin, glucagon, somatostatin, and growth hormone-releasing factor and showed evidence of widespread nesidioblastosis. |
1986-07-22 |
2023-08-11 |
Not clear |
| K S Polonsky, B D Given, W Pugh, J Licinio-Paixao, J E Thompson, T Karrison, A H Rubenstei. Calculation of the systemic delivery rate of insulin in normal man. The Journal of clinical endocrinology and metabolism. vol 63. issue 1. 1986-07-18. PMID:3519643. |
endogenous insulin secretion was suppressed by somatostatin, and insulin was infused exogenously via a peripheral vein. |
1986-07-18 |
2023-08-11 |
human |
| R Gross, P Mialh. Free fatty acids and pancreatic function in the duck. Acta endocrinologica. vol 112. issue 1. 1986-07-07. PMID:2872764. |
oleate, 2 mmol/l, increased the output rates of pancreatic somatostatin, glucagon and insulin. |
1986-07-07 |
2023-08-11 |
Not clear |
| L Christin, C A Nacht, O Vernet, E Ravussin, E Jéquier, K J Acheso. Insulin. Its role in the thermic effect of glucose. The Journal of clinical investigation. vol 77. issue 6. 1986-07-02. PMID:2872232. |
to investigate the possible role of insulin per se in the thermic response to glucose/insulin infusions, respiratory exchange measurements were performed on eight healthy young men for 45 min before and 210 min after somatostatin infusion. |
1986-07-02 |
2023-08-11 |
Not clear |
| P M Bell, R G Firth, R A Rizz. Effects of hyperglycemia on glucose production and utilization in humans. Measurement with [23H]-, [33H]-, and [614C]glucose. Diabetes. vol 35. issue 6. 1986-07-01. PMID:3519321. |
plasma glucose was then raised from 95 to 135 to 175 mg x dl-1 while insulin secretion was inhibited, and circulating insulin, glucagon, and growth hormone concentrations were maintained constant by infusion of these hormones and somatostatin. |
1986-07-01 |
2023-08-11 |
human |
| M Dreyer, S Matthaei, J Kühnau, H W Rüdige. Prolonged plasma half-life of insulin in patients with a genetic defect of high affinity binding sites. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 18. issue 4. 1986-06-27. PMID:2872151. |
intravenous infusion of somatostatin was used to inhibit the insulin secretion. |
1986-06-27 |
2023-08-11 |
Not clear |
| G Ribes, Y Sauvaire, C Da Costa, J C Baccou, M M Loubatieres-Marian. Antidiabetic effects of subfractions from fenugreek seeds in diabetic dogs. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). vol 182. issue 2. 1986-06-18. PMID:2871558. |
the addition of subfraction "a" to insulin treatment resulted in a clear decrease of hyperglycemia and glycosuria accompanied by a reduction of the high plasma glucagon and somatostatin levels in diabetic dogs. |
1986-06-18 |
2023-08-11 |
Not clear |
| M Beylot, J A Chayvialle, B Rebattu, G Sautot, R Cohen, J P Riou, R Morne. Regulation of peripheral plasma somatostatin like immunoreactivity in type I diabetes: role of the degree of metabolic control. Diabete & metabolisme. vol 12. issue 1. 1986-06-13. PMID:3516750. |
we have determined peripheral venous somatostatin like immunoreactivity (sli) levels in 11 normal subjects (blood glucose--bg--: 4.4 +/- 0.1 mm; ketone bodies--kb--: 90 +/- 12 microm; plasma free fatty acids--ffa --: 340 +/- 42 microm), 4 biostator controlled insulin dependent diabetics (bg: 5.4 +/- 0.2 mm; ffa: 418 +/- 38 microm; kb: 226 +/- 41 microm) and 7 poorly controlled ketotic diabetics (bg: 10.8 +/- 1.3 mm; ffa: 915 +/- 19 microm; kb: 2490 +/- 576 microm). |
1986-06-13 |
2023-08-11 |
human |
| B Laarveld, D E Kerr, R P Brockma. Effects of growth hormone on glucose and acetate metabolism in sheep. Comparative biochemistry and physiology. A, Comparative physiology. vol 83. issue 3. 1986-06-03. PMID:2870845. |
to maintain low levels of insulin somatostatin was infused with and without gh. |
1986-06-03 |
2023-08-11 |
Not clear |
| T N Barry, G J Faichney, C Redekop. Gastro-intestinal tract function in sheep infused with somatostatin. Australian journal of biological sciences. vol 38. issue 4. 1986-06-02. PMID:2871827. |
the somatostatin infusion increased the concentration of somatostatin in venous plasma within the physiological range from 10 to 76 ng/l, decreased plasma concentrations of prolactin and thyroxine, but had no effect upon plasma concentrations of insulin and glucagon. |
1986-06-02 |
2023-08-11 |
Not clear |
| K Uvnäs-Moberg, B Posloncec, L Ahlber. Influence on plasma levels of somatostatin, gastrin, glucagon, insulin and VIP-like immunoreactivity in peripheral venous blood of anaesthetized cats induced by low intensity afferent stimulation of the sciatic nerve. Acta physiologica Scandinavica. vol 126. issue 2. 1986-05-27. PMID:2871695. |
influence on plasma levels of somatostatin, gastrin, glucagon, insulin and vip-like immunoreactivity in peripheral venous blood of anaesthetized cats induced by low intensity afferent stimulation of the sciatic nerve. |
1986-05-27 |
2023-08-11 |
Not clear |
| K Uvnäs-Moberg, B Posloncec, L Ahlber. Influence on plasma levels of somatostatin, gastrin, glucagon, insulin and VIP-like immunoreactivity in peripheral venous blood of anaesthetized cats induced by low intensity afferent stimulation of the sciatic nerve. Acta physiologica Scandinavica. vol 126. issue 2. 1986-05-27. PMID:2871695. |
blood samples were collected in a peripheral vein and the plasma levels of somatostatin, gastrin, glucagon, insulin and vip-like immunoreactivity (below referred to as somatostatin, gastrin, glucagon, insulin and vip) were recorded by radioimmunoassay. |
1986-05-27 |
2023-08-11 |
Not clear |
| K Uvnäs-Moberg, B Posloncec, L Ahlber. Influence on plasma levels of somatostatin, gastrin, glucagon, insulin and VIP-like immunoreactivity in peripheral venous blood of anaesthetized cats induced by low intensity afferent stimulation of the sciatic nerve. Acta physiologica Scandinavica. vol 126. issue 2. 1986-05-27. PMID:2871695. |
somatostatin, gastrin and glucagon levels rose significantly, whereas in the case of insulin and vip a significant relationship between the effect of sciatic nerve stimulation and basal levels was established. |
1986-05-27 |
2023-08-11 |
Not clear |