| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Giulia Schillani, Elisabetta Martinis, Maria Anna Capozzo, Daniel Era, Tania Cristante, Giorgio Mustacchi, Maria Anna Conte, Maurizio DE Vanna, Luigi Grassi, Tullio Girald. Psychological response to cancer: role of 5-HTTLPR genetic polymorphism of serotonin transporter. Anticancer research. vol 30. issue 9. 2010-11-10. PMID:20944177. |
5-httlpr genetic polymorphism of serotonin transporter (sert) and stressful life events facilitate depression. |
2010-11-10 |
2023-08-12 |
Not clear |
| Suzanne M Cloonan, Aleksandra Drozgowska, Darren Fayne, D Clive William. The antidepressants maprotiline and fluoxetine have potent selective antiproliferative effects against Burkitt lymphoma independently of the norepinephrine and serotonin transporters. Leukemia & lymphoma. vol 51. issue 3. 2010-11-08. PMID:20141432. |
in this study, we also show evidence to support previous reports that the serotonin transporter (sert) has no involvement in antidepressant-mediated cell death, as sert-specific ligands were unable to prevent fluoxetine or maprotiline cell death and not all sert ligands could induce cell death. |
2010-11-08 |
2023-08-12 |
human |
| Jörn Reese, Adrian Kraschewski, Ion Anghelescu, Georg Winterer, Lutz G Schmidt, Jürgen Gallinat, Franz Rüschendorf, Hans Rommelspacher, Catrin Wernick. Haplotypes of dopamine and serotonin transporter genes are associated with antisocial personality disorder in alcoholics. Psychiatric genetics. vol 20. issue 4. 2010-11-04. PMID:20505557. |
the dopamine transporter (dat) and the serotonin transporter (sert) are involved in endophenotypes that are associated with these subtypes. |
2010-11-04 |
2023-08-12 |
Not clear |
| Yona Bismuth-Evenzal, Netta Roz, David Gurwitz, Moshe Rehav. N-methyl-citalopram: A quaternary selective serotonin reuptake inhibitor. Biochemical pharmacology. vol 80. issue 10. 2010-10-28. PMID:20696140. |
nmc recognized and blocked the human platelet serotonin transporter (sert) with similar affinity to that of citalopram as was evident from competition binding studies with [(3)h]citalopram and uptake studies with [(3)h]5-ht. |
2010-10-28 |
2023-08-12 |
mouse |
| Li Jijun, Li Zaiwang, Li Anyuan, Wang Shuzhen, Qi Fanghua, Zhao Lin, Lv Hon. Abnormal expression of dopamine and serotonin transporters associated with the pathophysiologic mechanism of Tourette syndrome. Neurology India. vol 58. issue 4. 2010-10-26. PMID:20739786. |
it is also well known that dopamine and serotonin transporters (dat and sert) are monoamine neurotransmitter transporters, which participate in the metabolism of da and 5-ht, respectively. |
2010-10-26 |
2023-08-12 |
Not clear |
| Julie L Wang, Eric C Deutsch, Shunichi Oya, Hank F Kun. FlipADAM: a potential new SPECT imaging agent for the serotonin transporter. Nuclear medicine and biology. vol 37. issue 5. 2010-10-14. PMID:20610162. |
single photon emission computed tomography (spect) imaging of the serotonin transporter (sert) in the brain is a useful tool for examining normal physiological functions and disease states involving the serotonergic system. |
2010-10-14 |
2023-08-12 |
Not clear |
| Nachwa Jarkas, Ronald J Voll, Larry Williams, Mark M Goodma. Validation of two fluoro-analogues of N,N-dimethyl-2-(2'-amino-4'-hydroxymethyl-phenylthio)benzylamine as serotonin transporter imaging agents using microPET. Nuclear medicine and biology. vol 37. issue 5. 2010-10-14. PMID:20610164. |
carbon-11 (c-11) n,n-dimethyl-2-(2'-amino-4'-hydroxymethyl-phenylthio)benzylamine ([(11)c]homadam) has been reported as highly specific and selective positron emission tomography (pet) radiotracer showing fast kinetics for the human brain serotonin transporter (sert). |
2010-10-14 |
2023-08-12 |
human |
| Peter Holm, Anders Ettrup, Anders B Klein, Martin A Santini, Mona El-Sayed, Anders B Elvang, Tine B Stensbøl, Jens D Mikkelsen, Gitte M Knudsen, Susana Azna. Plaque deposition dependent decrease in 5-HT2A serotonin receptor in AbetaPPswe/PS1dE9 amyloid overexpressing mice. Journal of Alzheimer's disease : JAD. vol 20. issue 4. 2010-10-12. PMID:20413853. |
[3h]-mdl100907, [3h]-escitalopram, and [11c]-pib autoradiography was performed for measuring 5-ht2a receptor, serotonin transporter (sert), and abeta plaque levels in medial prefrontal cortex (mpfc), prefrontal cortex (pfc), frontoparietal cortex (fpc), dorsal and ventral hippocampus, and somatosensory cortex. |
2010-10-12 |
2023-08-12 |
mouse |
| Gang Zhao, Guo-Wei Qin, Yue Gai, Li-He Gu. Structural identification of a new tri-p-coumaroylspermidine with serotonin transporter inhibition from safflower. Chemical & pharmaceutical bulletin. vol 58. issue 7. 2010-10-12. PMID:20606344. |
we previously reported that safflower (carthamus tinctorius l.) ethyl acetate extract (he) possessed an inhibitory action on serotonin (5ht) uptake in chinese hamster ovary (cho) cells expressing 5ht transporter (sert) (s6 cells). |
2010-10-12 |
2023-08-12 |
Not clear |
| Cristina García-Frigola, Eloísa Herrer. Zic2 regulates the expression of Sert to modulate eye-specific refinement at the visual targets. The EMBO journal. vol 29. issue 18. 2010-10-07. PMID:20676059. |
here, we report that, in addition, zic2 controls the refinement of eye-specific inputs in the visual targets by regulating directly the expression of the serotonin transporter (sert), which is involved in the modulation of activity-dependent mechanisms during the wiring of sensory circuits. |
2010-10-07 |
2023-08-12 |
Not clear |
| Murat Oz, Therissa Libby, Bronwyn Kivell, Vanaja Jaligam, Sammanda Ramamoorthy, Toni S Shippenber. Real-time, spatially resolved analysis of serotonin transporter activity and regulation using the fluorescent substrate, ASP+. Journal of neurochemistry. vol 114. issue 4. 2010-10-06. PMID:20524964. |
the serotonin transporter (sert) mediates clearance of serotonin from the synapse, thereby, regulating extracellular serotonin concentrations. |
2010-10-06 |
2023-08-12 |
human |
| Cody J Wenthur, Gustavo J Rodríguez, Charles P Kuntz, Eric L Barke. Conformational flexibility of transmembrane helix VII of the human serotonin transporter impacts ion dependence and transport. Biochemical pharmacology. vol 80. issue 9. 2010-10-06. PMID:20637736. |
the serotonin transporter (sert) regulates the serotonin concentration in the synapse and is a target of several antidepressant and psychostimulant drugs. |
2010-10-06 |
2023-08-12 |
human |
| Anne Baudry, Sophie Mouillet-Richard, Benoît Schneider, Jean-Marie Launay, Odile Kellerman. miR-16 targets the serotonin transporter: a new facet for adaptive responses to antidepressants. Science (New York, N.Y.). vol 329. issue 5998. 2010-10-04. PMID:20847275. |
the serotonin transporter (sert) ensures the recapture of serotonin and is the pharmacological target of selective serotonin reuptake inhibitor (ssri) antidepressants. |
2010-10-04 |
2023-08-12 |
mouse |
| D Erritzoe, V G Frokjaer, M T Haahr, J Kalbitzer, C Svarer, K K Holst, D L Hansen, T L Jernigan, S Lehel, G M Knudse. Cerebral serotonin transporter binding is inversely related to body mass index. NeuroImage. vol 52. issue 1. 2010-09-30. PMID:20382236. |
serotonergic neurotransmission is critically involved in eating behaviour; cerebral level of serotonin (5-ht) in animal models is inversely related to food intake and body weight and some effective anti-obesity agents involve blockade of the serotonin transporter (sert). |
2010-09-30 |
2023-08-12 |
human |
| D Erritzoe, V G Frokjaer, M T Haahr, J Kalbitzer, C Svarer, K K Holst, D L Hansen, T L Jernigan, S Lehel, G M Knudse. Cerebral serotonin transporter binding is inversely related to body mass index. NeuroImage. vol 52. issue 1. 2010-09-30. PMID:20382236. |
whether the sert has a direct role in the regulation of appetite and eating behaviour or whether the finding is due to a compensatory downregulation of sert secondary to other dysfunction(s) in the serotonergic transmitter system, such as low baseline serotonin levels, remains to be established. |
2010-09-30 |
2023-08-12 |
human |
| Yuan-Hwa Chou, Shyh-Jen Wang, Chun-Lung Lin, Wei-Chung Mao, Shin-Min Lee, Mei-Hsiu Lia. Decreased brain serotonin transporter binding in the euthymic state of bipolar I but not bipolar II disorder: a SPECT study. Bipolar disorders. vol 12. issue 3. 2010-09-29. PMID:20565438. |
previous positron emission tomography studies have demonstrated that serotonin transporter (sert) binding in the midbrain is decreased in the depressive state of bipolar disorder (bd). |
2010-09-29 |
2023-08-12 |
Not clear |
| Elizabeth A Daubert, Daniel S Heffron, James W Mandell, Barry G Condro. Serotonergic dystrophy induced by excess serotonin. Molecular and cellular neurosciences. vol 44. issue 3. 2010-09-27. PMID:20394820. |
our results also suggest that serotonin levels during early development determine later sensitivity of spheroid formation to manipulations of the serotonin transporter (sert). |
2010-09-27 |
2023-08-12 |
drosophila_melanogaster |
| Robert P Vertes, Stephanie B Linley, Walter B Hoove. Pattern of distribution of serotonergic fibers to the thalamus of the rat. Brain structure & function. vol 215. issue 1. 2010-09-23. PMID:20390296. |
few reports have examined the distribution of 5-ht fibers to the thalamus and none to our knowledge using immunoprocedures for the detection of the serotonin transporter (sert)-a very sensitive marker for 5-ht fibers. |
2010-09-23 |
2023-08-12 |
rat |
| Robert P Vertes, Stephanie B Linley, Walter B Hoove. Pattern of distribution of serotonergic fibers to the thalamus of the rat. Brain structure & function. vol 215. issue 1. 2010-09-23. PMID:20390296. |
using immunohistochemical methods for sert, we examined the pattern of distribution of 5-ht fibers to the thalamus in the rat. |
2010-09-23 |
2023-08-12 |
rat |
| Beate Niesler, Johannes Kapeller, Catherine Fell, Wendy Atkinson, Dorothee Möller, Christine Fischer, Peter Whorwell, Lesley A Houghto. 5-HTTLPR and STin2 polymorphisms in the serotonin transporter gene and irritable bowel syndrome: effect of bowel habit and sex. European journal of gastroenterology & hepatology. vol 22. issue 7. 2010-09-20. PMID:19561511. |
conflicting data exist on the association between functional polymorphisms in the serotonin reuptake transporter (sert) gene (slc6a4) and irritable bowel syndrome (ibs). |
2010-09-20 |
2023-08-12 |
human |