| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Joanna Solich, Agata Faron-Gorecka, Maciej Kusmider, Paulina Palach, Magdalena Gaska, Marta Dziedzicka-Wasylewsk. Norepinephrine transporter (NET) knock-out upregulates dopamine and serotonin transporters in the mouse brain. Neurochemistry international. vol 59. issue 2. 2011-11-22. PMID:21693154. |
in the present study we demonstrate that the life-long deletion of the noradrenaline transporter (net) induced up-regulation of two other monoamine transporters, dopamine and serotonin (dat and sert, respectively). |
2011-11-22 |
2023-08-12 |
mouse |
| Catherine F Capello, Chase H Bourke, James C Ritchie, Zachary N Stowe, D Jeffrey Newport, Amanda Nemeroff, Michael J Owen. Serotonin transporter occupancy in rats exposed to serotonin reuptake inhibitors in utero or via breast milk. The Journal of pharmacology and experimental therapeutics. vol 339. issue 1. 2011-11-22. PMID:21775476. |
the magnitude of serotonin reuptake inhibitor (sri) cns exposure was measured in three groups of rats using ex vivo autoradiography of the serotonin transporter (sert): 1) in utero, 2) postnatal clearance after birth, and 3) exposure through lactation. |
2011-11-22 |
2023-08-12 |
human |
| José J Rodríguez, Harun N Noristani, Walter B Hoover, Stephanie B Linley, Robert P Verte. Serotonergic projections and serotonin receptor expression in the reticular nucleus of the thalamus in the rat. Synapse (New York, N.Y.). vol 65. issue 9. 2011-11-15. PMID:21308802. |
we further characterized the distribution of 5-ht fibers to rt by using immunohistochemistry for 5-ht and for the 5ht transporter (sert) detection. |
2011-11-15 |
2023-08-12 |
rat |
| José J Rodríguez, Harun N Noristani, Walter B Hoover, Stephanie B Linley, Robert P Verte. Serotonergic projections and serotonin receptor expression in the reticular nucleus of the thalamus in the rat. Synapse (New York, N.Y.). vol 65. issue 9. 2011-11-15. PMID:21308802. |
in addition, serotonergic fibers (5-ht and sert positive) were richly distributed throughout rt, and 5-ht(1a) and 5-ht(2a) receptors were highly expressed on rt neurons and dendrites. |
2011-11-15 |
2023-08-12 |
rat |
| Eduard Maron, Innar Tõru, Jussi Hirvonen, Lauri Tuominen, Ville Lumme, Veiko Vasar, Jakov Shlik, David J Nutt, Semi Helin, Kjell Någren, Jari Tiihonen, Jarmo Hietal. Gender differences in brain serotonin transporter availability in panic disorder. Journal of psychopharmacology (Oxford, England). vol 25. issue 7. 2011-11-14. PMID:21148024. |
previously we detected lower brain 5-ht transporter (sert) availability in pd, but the findings were preliminary and mainly limited to female patients. |
2011-11-14 |
2023-08-12 |
human |
| Eduard Maron, Innar Tõru, Jussi Hirvonen, Lauri Tuominen, Ville Lumme, Veiko Vasar, Jakov Shlik, David J Nutt, Semi Helin, Kjell Någren, Jari Tiihonen, Jarmo Hietal. Gender differences in brain serotonin transporter availability in panic disorder. Journal of psychopharmacology (Oxford, England). vol 25. issue 7. 2011-11-14. PMID:21148024. |
the results suggest gender-dependent regional differences in brain sert availability and converge with previous pet findings of reduced 5-ht(1a) receptor binding in similar brain areas in pd. |
2011-11-14 |
2023-08-12 |
human |
| Gino Giannaccini, Laura Betti, Lionella Palego, Andrea Pirone, Lara Schmid, Mario Lanza, Laura Fabbrini, Caterina Pelosini, Margherita Maffei, Ferruccio Santini, Aldo Pinchera, Antonio Lucacchin. Serotonin transporter (SERT) and translocator protein (TSPO) expression in the obese ob/ob mouse. BMC neuroscience. vol 12. 2011-11-14. PMID:21299850. |
serotonin transporter (sert) and translocator protein (tspo) expression in the obese ob/ob mouse. |
2011-11-14 |
2023-08-12 |
mouse |
| Gino Giannaccini, Laura Betti, Lionella Palego, Andrea Pirone, Lara Schmid, Mario Lanza, Laura Fabbrini, Caterina Pelosini, Margherita Maffei, Ferruccio Santini, Aldo Pinchera, Antonio Lucacchin. Serotonin transporter (SERT) and translocator protein (TSPO) expression in the obese ob/ob mouse. BMC neuroscience. vol 12. 2011-11-14. PMID:21299850. |
the present study sought at examining the density and affinity of two proteins related to neurotransmission and cell metabolism, the serotonin transporter sert and the cholesterol import-benzodiazepine site tspo (translocator protein), in a rodent leptin-lacking mutant, the obese ob/ob mouse. |
2011-11-14 |
2023-08-12 |
mouse |
| Chiharu Sogawa, Norio Sogawa, Kazumi Ohyama, Ruri Kikura-Hanajiri, Yukihiro Goda, Ichiro Sora, Shigeo Kitayam. Methylone and monoamine transporters: correlation with toxicity. Current neuropharmacology. vol 9. issue 1. 2011-11-10. PMID:21886563. |
we examined here the effects of methylone on the transporters for dopamine (dat), norepinephrine (net), and serotonin (sert), using a heterologous expression system in cho cells, in association with its cytotoxicity. |
2011-11-10 |
2023-08-12 |
Not clear |
| Y Takamatsu, H Yamamoto, Y Hagino, A Markou, K Iked. The Selective Serotonin Reuptake Inhibitor Paroxetine, but not Fluvoxamine, Decreases Methamphetamine Conditioned Place Preference in Mice. Current neuropharmacology. vol 9. issue 1. 2011-11-10. PMID:21886565. |
recently, we showed that fluoxetine, a selective serotonin reuptake inhibitor (ssri), decreased meth conditioned place preference (cpp), suggesting that serotonin transporter (sert) inhibition reduces the rewarding effects of meth. |
2011-11-10 |
2023-08-12 |
mouse |
| Dominik K Biezonski, Jerrold S Meye. The Nature of 3, 4-Methylenedioxymethamphetamine (MDMA)-Induced Serotonergic Dysfunction: Evidence for and Against the Neurodegeneration Hypothesis. Current neuropharmacology. vol 9. issue 1. 2011-11-10. PMID:21886568. |
neuroimaging studies further suggest that at least one of these markers, the plasma membrane serotonin transporter (sert), may also be reduced in heavy ecstasy users. |
2011-11-10 |
2023-08-12 |
rat |
| Y Hagino, Y Takamatsu, H Yamamoto, T Iwamura, D L Murphy, G R Uhl, I Sora, K Iked. Effects of MDMA on Extracellular Dopamine and Serotonin Levels in Mice Lacking Dopamine and/or Serotonin Transporters. Current neuropharmacology. vol 9. issue 1. 2011-11-10. PMID:21886569. |
the present study investigated the effects of mdma on extracellular dopamine (da(ex)) and serotonin (5-ht(ex)) levels in the striatum and prefrontal cortex (pfc) using in vivo microdialysis techniques in mice lacking da transporters (dat) and/or 5-ht transporters (sert). |
2011-11-10 |
2023-08-12 |
mouse |
| Y Hagino, Y Takamatsu, H Yamamoto, T Iwamura, D L Murphy, G R Uhl, I Sora, K Iked. Effects of MDMA on Extracellular Dopamine and Serotonin Levels in Mice Lacking Dopamine and/or Serotonin Transporters. Current neuropharmacology. vol 9. issue 1. 2011-11-10. PMID:21886569. |
the results confirm that mdma acts at both dat and sert and increases da(ex) and 5-ht(ex). |
2011-11-10 |
2023-08-12 |
mouse |
| Morten Ziebel. Evaluation of the superselective radioligand [123I]PE2I for imaging of the dopamine transporter in SPECT. Danish medical bulletin. vol 58. issue 5. 2011-10-19. PMID:21535991. |
123-i-labelled n-(3-iodoprop-2e-enyl)-2-β-carbomethoxy-3β-(4-methylphenyl) nortropane, named pe2i, is a relatively new radioligand that has about 10-fold higher in vitro selectivity for the dat than for the serotonin transporter (sert) compared to the slightly older but very used and licensed radioligand [123i]fp-cit (datscan). |
2011-10-19 |
2023-08-12 |
human |
| Chong-Bin Zhu, Kathryn M Lindler, Nicholas G Campbell, James S Sutcliffe, William A Hewlett, Randy D Blakel. Colocalization and regulated physical association of presynaptic serotonin transporters with A₃ adenosine receptors. Molecular pharmacology. vol 80. issue 3. 2011-10-18. PMID:21705486. |
treatment of a₃ar/sert-cotransfected chinese hamster ovary cells with the a₃ar agonist n⁶-(3-iodobenzyl)-n-methyl-5'-carbamoyladenosine (1 μm, 10 min), conditions previously reported to increase sert surface expression and 5-ht uptake activity, enhanced the abundance of a₃ar/sert complexes in a pkgi-dependent manner. |
2011-10-18 |
2023-08-12 |
mouse |
| Alfredo Meneses, Georgina Perez-Garcia, Teresa Ponce-Lopez, Ruth Tellez, Carlos Castill. Serotonin transporter and memory. Neuropharmacology. vol 61. issue 3. 2011-10-14. PMID:21276807. |
the serotonin transporter (sert) has been associated to diverse functions and diseases, though seldom to memory. |
2011-10-14 |
2023-08-12 |
Not clear |
| Liming Shao, Michael C Hewitt, Scott C Malcolm, Fengjiang Wang, Jianguo Ma, Una C Campbell, Nancy A Spicer, Sharon R Engel, Larry W Hardy, Zhi-Dong Jiang, Rudy Schreiber, Kerry L Spear, Mark A Varne. Synthesis and pharmacological characterization of bicyclic triple reuptake inhibitor 3-aryl octahydrocyclopenta[c]pyrrole analogues. Journal of medicinal chemistry. vol 54. issue 15. 2011-10-07. PMID:21739935. |
the present work expands the chemical space known to offer potent inhibition of the serotonin transporter (sert), norepinephrine transporter (net), and dopamine transporter (dat) and discloses novel bicyclic octahydrocyclopenta[c]pyrrole and octahydro-1h-isoindole scaffolds as potent triple reuptake inhibitors (tris) for the potential treatment of depression. |
2011-10-07 |
2023-08-12 |
mouse |
| Lynette C Daws, Georgianna G Goul. Ontogeny and regulation of the serotonin transporter: providing insights into human disorders. Pharmacology & therapeutics. vol 131. issue 1. 2011-10-05. PMID:21447358. |
the 5-ht transporter (sert, 5-htt) is arguably the most powerful regulator of ambient extracellular 5-ht. |
2011-10-05 |
2023-08-12 |
human |
| Lynette C Daws, Georgianna G Goul. Ontogeny and regulation of the serotonin transporter: providing insights into human disorders. Pharmacology & therapeutics. vol 131. issue 1. 2011-10-05. PMID:21447358. |
sert is the high-affinity uptake mechanism for 5-ht and exerts tight control over the strength and duration of serotonergic neurotransmission. |
2011-10-05 |
2023-08-12 |
human |
| Jacob Andersen, Nicolai Stuhr-Hansen, Linda Zachariassen, Søren Toubro, Stinna M R Hansen, Jonas N N Eildal, Andrew D Bond, Klaus P Bøgesø, Benny Bang-Andersen, Anders S Kristensen, Kristian Strømgaar. Molecular determinants for selective recognition of antidepressants in the human serotonin and norepinephrine transporters. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 29. 2011-10-03. PMID:21730142. |
inhibitors of the serotonin transporter (sert) and norepinephrine transporter (net) are widely used in the treatment of major depressive disorder. |
2011-10-03 |
2023-08-12 |
human |