| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Balasubramaniam Annamalai, Padmanabhan Mannangatti, Obulakshmi Arapulisamy, Toni S Shippenberg, Lankupalle D Jayanthi, Sammanda Ramamoorth. Tyrosine phosphorylation of the human serotonin transporter: a role in the transporter stability and function. Molecular pharmacology. vol 81. issue 1. 2012-02-07. PMID:21992875. |
moreover, src-coexpression increased total and cell surface expression of y47f and y142f sert mutants without affecting their 5-ht transport capacity. |
2012-02-07 |
2023-08-12 |
human |
| Balasubramaniam Annamalai, Padmanabhan Mannangatti, Obulakshmi Arapulisamy, Toni S Shippenberg, Lankupalle D Jayanthi, Sammanda Ramamoorth. Tyrosine phosphorylation of the human serotonin transporter: a role in the transporter stability and function. Molecular pharmacology. vol 81. issue 1. 2012-02-07. PMID:21992875. |
these results provide the first evidence that sert tyrosine phosphorylation supports transporter protein stability and 5ht transport. |
2012-02-07 |
2023-08-12 |
human |
| M A Starr, M E Page, B D Waterhous. Effects of repeated 3,4-methylenedioxymethamphetamine administration on neurotransmitter efflux and sensory-evoked discharge in the ventral posterior medial thalamus. The Journal of pharmacology and experimental therapeutics. vol 340. issue 1. 2012-02-02. PMID:21984836. |
however, mdma interactions with the serotonin transporter (sert) and subsequent enhancement of serotonin neurotransmission are well known. |
2012-02-02 |
2023-08-12 |
rat |
| Kevin H Chen, Edmund A Reese, Hyung-Wook Kim, Stanley I Rapoport, Jagadeesh S Ra. Disturbed neurotransmitter transporter expression in Alzheimer's disease brain. Journal of Alzheimer's disease : JAD. vol 26. issue 4. 2012-01-26. PMID:21743130. |
we hypothesized that altered reuptake of neurotransmitters by vesicular glutamate transporters (vgluts), excitatory amino acid transporters (eaats), the vesicular acetylcholine transporter (vacht), the serotonin reuptake transporter (sert), or the dopamine reuptake transporter (dat) are involved in the neurotransmission imbalance in ad. |
2012-01-26 |
2023-08-12 |
Not clear |
| Yu Shian Cheng, Kao Chin Chen, Yen Kuang Yang, Po See Chen, Tzung Lieh Yeh, I Hui Lee, Yun-Hsuan Chang, Mei-Hsiu Lia. No seasonal variation in human midbrain serotonin transporter availability in Taiwan. Psychiatry research. vol 194. issue 3. 2012-01-26. PMID:22041533. |
sixty-six healthy participants were recruited, and single photon emission computed tomography ([¹²³i]-adam spect) was used to investigate the association between serotonin transporter (sert) availability and duration of sunlight exposure in taiwan, a subtropical country. |
2012-01-26 |
2023-08-12 |
human |
| Ju-Wei Hsu, Shyh-Jen Wang, Chun-Lung Lin, Wen-Chi Hsieh, Jiing-Feng Lirng, Yuh-Chiang Shen, Mei-Hsiu Liao, Yuan-Hwa Cho. Short term vs. long term test-retest reproducibility of ¹²³I-ADAM for the binding of serotonin transporters in the human brain. Psychiatry research. vol 194. issue 3. 2012-01-26. PMID:22079655. |
previous brain imaging studies have demonstrated a seasonal difference of serotonin transporter (sert) binding in the human brain. |
2012-01-26 |
2023-08-12 |
human |
| Sankar Manepalli, Laura M Geffert, Christopher K Surratt, Jeffry D Madur. Discovery of novel selective serotonin reuptake inhibitors through development of a protein-based pharmacophore. Journal of chemical information and modeling. vol 51. issue 9. 2012-01-20. PMID:21834587. |
the serotonin transporter (sert), a member of the neurotransmitter sodium symporter (nss) family, is responsible for the reuptake of serotonin from the synaptic cleft to maintain neurotransmitter homeostasis. |
2012-01-20 |
2023-08-12 |
Not clear |
| C L Bethea, A W Smith, M L Centeno, A P Redd. Long-term ovariectomy decreases serotonin neuron number and gene expression in free ranging macaques. Neuroscience. vol 192. 2012-01-18. PMID:21763405. |
in macaques, ovarian steroid administration to ovariectomized (ovx) individuals improves serotonin neural function through actions on pivotal serotonin-related genes and proteins, such as tph2 (tryptophan hydroxylase 2), sert (serotonin reuptake transporter), and the 5ht1a autoreceptor. |
2012-01-18 |
2023-08-12 |
Not clear |
| C L Bethea, A W Smith, M L Centeno, A P Redd. Long-term ovariectomy decreases serotonin neuron number and gene expression in free ranging macaques. Neuroscience. vol 192. 2012-01-18. PMID:21763405. |
in summary, long-term ovarian steroid loss resulted in fewer serotonin neurons and overall lower fev, tph2, sert, and 5ht1a gene expression. |
2012-01-18 |
2023-08-12 |
Not clear |
| Sara Trowbridge, Nicolas Narboux-Nême, Patricia Gaspa. Genetic models of serotonin (5-HT) depletion: what do they tell us about the developmental role of 5-HT? Anatomical record (Hoboken, N.J. : 2007). vol 294. issue 10. 2012-01-17. PMID:20818612. |
serotonin (5-ht) depletion has been obtained via targeting of genes involved in 5-ht synthesis (tph1 and tph2), specification and determination of the 5-ht phenotype during development (gata3, pet1, and lmx1b), and 5-ht storage or clearance (vmat2 and sert). |
2012-01-17 |
2023-08-12 |
Not clear |
| Synia Haub, Yvonne Ritze, Inga Ladel, Karolin Saum, Astrid Hubert, Astrid Spruss, Christian Trautwein, Stephan C Bischof. Serotonin receptor type 3 antagonists improve obesity-associated fatty liver disease in mice. The Journal of pharmacology and experimental therapeutics. vol 339. issue 3. 2012-01-12. PMID:21903748. |
we determined markers of liver damage and inflammation, portal endotoxin levels, and duodenal concentrations of serotonin, serotonin-reuptake transporter (sert), occludin, and claudin-1. |
2012-01-12 |
2023-08-12 |
mouse |
| Synia Haub, Yvonne Ritze, Inga Ladel, Karolin Saum, Astrid Hubert, Astrid Spruss, Christian Trautwein, Stephan C Bischof. Serotonin receptor type 3 antagonists improve obesity-associated fatty liver disease in mice. The Journal of pharmacology and experimental therapeutics. vol 339. issue 3. 2012-01-12. PMID:21903748. |
tropisetron treatment also caused a reduction of elevated serotonin levels and an increase of sert in the duodenum of ob/ob mice. |
2012-01-12 |
2023-08-12 |
mouse |
| Swen Hesse, Katarina Stengler, Ralf Regenthal, Marianne Patt, Georg-Alexander Becker, Annegret Franke, Heike Knüpfer, Philipp M Meyer, Julia Luthardt, Ina Jahn, Donald Lobsien, Wolfgang Heinke, Peter Brust, Ulrich Hegerl, Osama Sabr. The serotonin transporter availability in untreated early-onset and late-onset patients with obsessive-compulsive disorder. The international journal of neuropsychopharmacology. vol 14. issue 5. 2012-01-06. PMID:21232166. |
the pathogenetic role of central serotonin transporters (sert) in obsessive-compulsive disorder (ocd) has been investigated in vivo by positron emission tomography (pet) or single-photon emission computed tomography (spect) studies with inconsistent results. |
2012-01-06 |
2023-08-12 |
Not clear |
| T Markoutsaki, T Karantanos, M Gazouli, N P Anagnou, S D Ladas, D G Karamanoli. Serotonin transporter and G protein beta 3 subunit gene polymorphisms in Greeks with irritable bowel syndrome. Digestive diseases and sciences. vol 56. issue 11. 2011-12-27. PMID:21559741. |
polymorphisms in the serotonin transporter (sert) and g protein β3 subunit (gnb3) genes might contribute to the pathophysiology of irritable bowel syndrome (ibs). |
2011-12-27 |
2023-08-12 |
human |
| Meike Heeren, Karin Weissenborn, Dimitrios Arvanitis, Martin Bokemeyer, Annemarie Goldbecker, Argyro Tountopoulou, Thomas Peschel, Julian Grosskreutz, Hartmut Hecker, Ralph Buchert, Georg Berdin. Cerebral glucose utilisation in hepatitis C virus infection-associated encephalopathy. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 31. issue 11. 2011-12-27. PMID:21629258. |
therefore, 15 patients who reported increasing chronic fatigue, mood alterations, and/or cognitive decline since their hcv infection underwent neurologic and neuropsychological examination, magnetic resonance imaging, (18)f-fluoro-deoxy-glucose positron emission tomography of the brain, and single photon emission tomography of striatal dopamine and midbrain serotonin transporter (sert) availability. |
2011-12-27 |
2023-08-12 |
Not clear |
| Rianne M Blom, Jack F Samuels, Mark A Riddle, O Joseph Bienvenu, Marco A Grados, Irving M Reti, William W Eaton, Kung-Yee Liang, Gerald Nestad. Association between a serotonin transporter promoter polymorphism (5HTTLPR) and personality disorder traits in a community sample. Journal of psychiatric research. vol 45. issue 9. 2011-12-23. PMID:21450307. |
the serotonin transporter (sert) polymorphism (5httlpr) has been reported to be associated with several psychiatric conditions. |
2011-12-23 |
2023-08-12 |
Not clear |
| Emily Karanges, Kong M Li, Craig Motbey, Paul D Callaghan, Andrew Katsifis, Iain S McGrego. Differential behavioural and neurochemical outcomes from chronic paroxetine treatment in adolescent and adult rats: a model of adverse antidepressant effects in human adolescents? The international journal of neuropsychopharmacology. vol 14. issue 4. 2011-12-16. PMID:21329552. |
subsequent ex-vivo analyses examined serum prx concentrations, striatal neurotransmitter content, and regional serotonin and dopamine transporter (sert, dat) binding density. |
2011-12-16 |
2023-08-12 |
human |
| Yan Chi, Xin-guang Liu, Hua-hong Wang, Yi-xuan L. [The expression of mucosal IL-1β, TNFα and serotonin transporter in chronic visceral hypersensitivity rats]. Zhonghua nei ke za zhi. vol 49. issue 9. 2011-12-02. PMID:21092452. |
to assess the expression of tnfα, il-1β and the serotonin transporter (sert) in adult rats of chronic visceral hypersensitivity induced by colon irritation during postnatal development, and to provide evidence to clarify the complex relationship between inflammatory cytokines and sert among visceral hypersensitivity. |
2011-12-02 |
2023-08-12 |
rat |
| H N Noristani, R S Meadows, M Olabarria, A Verkhratsky, J J Rodrígue. Increased hippocampal CA1 density of serotonergic terminals in a triple transgenic mouse model of Alzheimer's disease: an ultrastructural study. Cell death & disease. vol 2. 2011-11-28. PMID:21918544. |
we recently demonstrated an increase in 5-ht transporter (sert) fibre density in the hippocampal ca1 in an ad triple transgenic mouse model (3xtg-ad). |
2011-11-28 |
2023-08-12 |
mouse |
| Alessia Malaguti, David Rossini, Adelio Lucca, Lorenzo Magri, Cristina Lorenzi, Adele Pirovano, Christina Colombo, Enrico Smeraldi, Raffaella Zanard. Role of COMT, 5-HT(1A) , and SERT genetic polymorphisms on antidepressant response to Transcranial Magnetic Stimulation. Depression and anxiety. vol 28. issue 7. 2011-11-23. PMID:21449006. |
role of comt, 5-ht(1a) , and sert genetic polymorphisms on antidepressant response to transcranial magnetic stimulation. |
2011-11-23 |
2023-08-12 |
Not clear |