| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eva Latorre, Carmen Mendoza, Nyurky Matheus, Marta Castro, Laura Grasa, José E Mesonero, Ana I Alcald. IL-10 modulates serotonin transporter activity and molecular expression in intestinal epithelial cells. Cytokine. vol 61. issue 3. 2013-08-27. PMID:23410504. |
treatment with il-10 was assessed and sert activity was determined by 5-ht uptake. |
2013-08-27 |
2023-08-12 |
Not clear |
| Joseph J Gallagher, Xiaowei Zhang, F Scott Hall, George R Uhl, Elaine L Bearer, Russell E Jacob. Altered reward circuitry in the norepinephrine transporter knockout mouse. PloS one. vol 8. issue 3. 2013-08-27. PMID:23469209. |
this is similar to previous results observed for the dopamine transporter (dat) knockout mouse, but dissimilar from work with serotonin transporter (sert) knockout mice where mn(2+) tracings extended to more posterior structures than in wildtype animals. |
2013-08-27 |
2023-08-12 |
mouse |
| Filippo Andreetta, Nicholas M Barnes, Paul B Wren, Lucia Carbon. p38 MAP kinase activation does not stimulate serotonin transport in rat brain: Implications for sickness behaviour mechanisms. Life sciences. vol 93. issue 1. 2013-08-27. PMID:23727352. |
available data showed that cytokines affect the serotonin transporter (sert) activity through p38 map kinase (mapk)-dependent mechanisms in some cell lines and mice neurons (zhu et al., neuropsychopharmacology, 2006; 31:2121-31). |
2013-08-27 |
2023-08-12 |
mouse |
| Steven Combs, Kristian Kaufmann, Julie R Field, Randy D Blakely, Jens Meile. Y95 and E444 interaction required for high-affinity S-citalopram binding in the human serotonin transporter. ACS chemical neuroscience. vol 2. issue 2. 2013-08-23. PMID:22778858. |
the antidepressant citalopram blocks sert and thereby inhibits the transport of 5-ht. |
2013-08-23 |
2023-08-12 |
human |
| Evan J Kyzar, Mimi Pham, Andrew Roth, Jonathan Cachat, Jeremy Green, Siddharth Gaikwad, Allan V Kaluef. Alterations in grooming activity and syntax in heterozygous SERT and BDNF knockout mice: the utility of behavior-recognition tools to characterize mutant mouse phenotypes. Brain research bulletin. vol 89. issue 5-6. 2013-08-16. PMID:22951260. |
serotonin transporter (sert) and brain-derived neurotrophic factor (bdnf) are key modulators of molecular signaling, cognition and behavior. |
2013-08-16 |
2023-08-12 |
mouse |
| Kristofer Thorslund, Beni Amatya, Ann Eriksson Dufva, Klas Nordlin. The expression of serotonin transporter protein correlates with the severity of psoriasis and chronic stress. Archives of dermatological research. vol 305. issue 2. 2013-08-12. PMID:23161175. |
there is an increased expression of the serotonin transporter protein (sert) in involved psoriatic skin as compared to non-involved psoriatic skin and normal skin. |
2013-08-12 |
2023-08-12 |
Not clear |
| Courtney Huff, Nirmal Bhide, Allen Schroering, Bryan K Yamamoto, Gary A Gudelsk. Effect of repeated exposure to MDMA on the function of the 5-HT transporter as assessed by synaptosomal 5-HT uptake. Brain research bulletin. vol 91. 2013-08-12. PMID:23318273. |
recent studies have demonstrated that a preconditioning regimen (i.e., repeated low doses) of mdma provides protection against the reductions in tissue concentrations of 5-ht and 5-ht transporter (sert) density and/or expression produced by a subsequent binge regimen of mdma. |
2013-08-12 |
2023-08-12 |
rat |
| Courtney Huff, Nirmal Bhide, Allen Schroering, Bryan K Yamamoto, Gary A Gudelsk. Effect of repeated exposure to MDMA on the function of the 5-HT transporter as assessed by synaptosomal 5-HT uptake. Brain research bulletin. vol 91. 2013-08-12. PMID:23318273. |
in the present study, the effects of preconditioning and binge treatment regimens of mdma on sert function were assessed by synaptosomal 5-ht uptake. |
2013-08-12 |
2023-08-12 |
rat |
| Les Iversen, Simon Gibbons, Ric Treble, Vincent Setola, Xi-Ping Huang, Bryan L Rot. Neurochemical profiles of some novel psychoactive substances. European journal of pharmacology. vol 700. issue 1-3. 2013-08-05. PMID:23261499. |
thirteen of the test substances acted as inhibitors of monoamine uptake at submicromolar concentrations, including 9 potent inhibitors of the dopamine transporter (dat), 12 potent inhibitors of the norepinephrine transporter (net) and 4 potent inhibitors of the serotonin transporter (sert). |
2013-08-05 |
2023-08-12 |
human |
| Tanel Visnapuu, Sirli Raud, Maarja Loomets, Riin Reimets, Silva Sütt, Hendrik Luuk, Mario Plaas, Sulev Kõks, Vallo Volke, Aet Alttoa, Jaanus Harro, Eero Vasa. Wfs1-deficient mice display altered function of serotonergic system and increased behavioral response to antidepressants. Frontiers in neuroscience. vol 7. 2013-08-05. PMID:23914152. |
in gene expression studies, the levels of 5-ht transporter (sert) were significantly reduced in the pons of homozygous animals. |
2013-08-05 |
2023-08-12 |
mouse |
| Tanel Visnapuu, Sirli Raud, Maarja Loomets, Riin Reimets, Silva Sütt, Hendrik Luuk, Mario Plaas, Sulev Kõks, Vallo Volke, Aet Alttoa, Jaanus Harro, Eero Vasa. Wfs1-deficient mice display altered function of serotonergic system and increased behavioral response to antidepressants. Frontiers in neuroscience. vol 7. 2013-08-05. PMID:23914152. |
taken together, the blunted 5-ht metabolism and reduced levels of sert are a likely reason for the elevated sensitivity of these mice to the action of imipramine and paroxetine. |
2013-08-05 |
2023-08-12 |
mouse |
| Akihiro Takano, Christer Halldin, Lars Fard. SERT and NET occupancy by venlafaxine and milnacipran in nonhuman primates: a PET study. Psychopharmacology. vol 226. issue 1. 2013-07-30. PMID:23090625. |
serotonin and norepinephrine reuptake inhibitors (snris) are antidepressants which have high affinity to both serotonin transporter (sert) and norepinephrine transporter (net). |
2013-07-30 |
2023-08-12 |
Not clear |
| Saba Abdul-Hussein, Juni Andréll, Christopher G Tat. Thermostabilisation of the serotonin transporter in a cocaine-bound conformation. Journal of molecular biology. vol 425. issue 12. 2013-07-29. PMID:23706649. |
we have therefore used this approach on the cocaine-sensitive rat serotonin transporter (sert). |
2013-07-29 |
2023-08-12 |
rat |
| Narattaphol Charoenphandhu, Amporn Nuntapornsak, Kannikar Wongdee, Nateetip Krishnamra, Jantarima Charoenphandh. Upregulated mRNA levels of SERT, NET, MAOB, and BDNF in various brain regions of ovariectomized rats exposed to chronic aversive stimuli. Molecular and cellular biochemistry. vol 375. issue 1-2. 2013-07-26. PMID:23208077. |
herein, we used quantitative real-time pcr to quantify the mrna levels of serotonin reuptake transporter (sert), norepinephrine transporter (net), monoamine oxidase-b (maob), tryptophan hydroxylase (tph), and tyrosine hydroxylase (th) in various brain regions of ovariectomized (ovx) rats which had been exposed for 4 weeks to chronic aversive stimuli (cas), such as water deprivation, cage tilt, and illumination. |
2013-07-26 |
2023-08-12 |
rat |
| Floor van Heesch, Jolanda Prins, Jan Pieter Konsman, Koen G C Westphal, Berend Olivier, Aletta D Kraneveld, S Mechiel Kort. Lipopolysaccharide-induced anhedonia is abolished in male serotonin transporter knockout rats: an intracranial self-stimulation study. Brain, behavior, and immunity. vol 29. 2013-07-26. PMID:23274951. |
previously, it has been shown that selective serotonin re-uptake inhibitors decrease serum pro-inflammatory cytokine levels and that pro-inflammatory cytokines increase activity of the serotonin transporter (sert). |
2013-07-26 |
2023-08-12 |
rat |
| Floor van Heesch, Jolanda Prins, Jan Pieter Konsman, Koen G C Westphal, Berend Olivier, Aletta D Kraneveld, S Mechiel Kort. Lipopolysaccharide-induced anhedonia is abolished in male serotonin transporter knockout rats: an intracranial self-stimulation study. Brain, behavior, and immunity. vol 29. 2013-07-26. PMID:23274951. |
a single intraperitoneal injection of lps was used to induce a pro-inflammatory immune response in male serotonin transporter wild type (sert(+/+)), heterozygous (sert(+/-)) and knockout (sert(-/-)) rats. |
2013-07-26 |
2023-08-12 |
rat |
| Yvonne Couch, Daniel C Anthony, Oleg Dolgov, Alexander Revischin, Barry Festoff, Ana Isabel Santos, Harry W Steinbusch, Tatyana Strekalov. Microglial activation, increased TNF and SERT expression in the prefrontal cortex define stress-altered behaviour in mice susceptible to anhedonia. Brain, behavior, and immunity. vol 29. 2013-07-26. PMID:23305936. |
compared to resilient animals, susceptible mice showed elevated expression of tumour necrosis factor alpha (tnf) and the 5-ht transporter (sert) in the pre-frontal area. |
2013-07-26 |
2023-08-12 |
mouse |
| Jalal Soubhye, Iyas Aldib, Betina Elfving, Michel Gelbcke, Paul G Furtmüller, Manuel Podrecca, Raphaël Conotte, Jean-Marie Colet, Alexandre Rousseau, Florence Reye, Ahmad Sarakbi, Michel Vanhaeverbeek, Jean-Michel Kauffmann, Christian Obinger, Jean Nève, Martine Prévost, Karim Zouaoui Boudjeltia, Francois Dufrasne, Pierre Van Antwerpe. Design, synthesis, and structure-activity relationship studies of novel 3-alkylindole derivatives as selective and highly potent myeloperoxidase inhibitors. Journal of medicinal chemistry. vol 56. issue 10. 2013-07-23. PMID:23581551. |
(aminoalkyl)fluoroindole derivatives were detected to be very potent mpo inhibitors; however, they also promote inhibition of the serotonin reuptake transporter (sert) at the same concentration range. |
2013-07-23 |
2023-08-12 |
human |
| Nuria Lauzurica, Luis García-García, José A Fuentes, Mercedes Delgad. Hypophagia and induction of serotonin transporter gene expression in raphe nuclei of male and female rats after short-term fluoxetine treatment. Journal of physiology and biochemistry. vol 69. issue 1. 2013-07-22. PMID:22730080. |
to explore the role of the 5-ht transporter (serotonin transporter (sert)) in the short-term action of serotonin selective reuptake inhibitor fluoxetine, rats were i.p. |
2013-07-22 |
2023-08-12 |
human |
| Judith R Homberg, Daniel L A van den Hov. The serotonin transporter gene and functional and pathological adaptation to environmental variation across the life span. Progress in neurobiology. vol 99. issue 2. 2013-07-22. PMID:22954594. |
here, we discuss g×e studies focussing on serotonin transporter (5-htt, sert, slc6a4) gene variation in humans, monkeys, and rodents. |
2013-07-22 |
2023-08-12 |
human |