| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Masayuki Fujiwara, Hikaru Yamamoto, Tatsuhiro Miyagi, Takahiro Seki, Shigeru Tanaka, Izumi Hide, Norio Saka. Effects of the chemical chaperone 4-phenylbutylate on the function of the serotonin transporter (SERT) expressed in COS-7 cells. Journal of pharmacological sciences. vol 122. issue 2. 2014-01-09. PMID:23676312. |
effects of the chemical chaperone 4-phenylbutylate on the function of the serotonin transporter (sert) expressed in cos-7 cells. |
2014-01-09 |
2023-08-12 |
Not clear |
| Masayuki Fujiwara, Hikaru Yamamoto, Tatsuhiro Miyagi, Takahiro Seki, Shigeru Tanaka, Izumi Hide, Norio Saka. Effects of the chemical chaperone 4-phenylbutylate on the function of the serotonin transporter (SERT) expressed in COS-7 cells. Journal of pharmacological sciences. vol 122. issue 2. 2014-01-09. PMID:23676312. |
the serotonin transporter (sert) is involved in various psychiatric disorders, including depression and autism. |
2014-01-09 |
2023-08-12 |
Not clear |
| Hang Zhang, Meng Xu, Jia Xia, Ren-Yi Qi. Association between serotonin transporter (SERT) gene polymorphism and idiopathic pulmonary arterial hypertension: a meta-analysis and review of the literature. Metabolism: clinical and experimental. vol 62. issue 12. 2014-01-08. PMID:24075737. |
association between serotonin transporter (sert) gene polymorphism and idiopathic pulmonary arterial hypertension: a meta-analysis and review of the literature. |
2014-01-08 |
2023-08-12 |
Not clear |
| Hang Zhang, Meng Xu, Jia Xia, Ren-Yi Qi. Association between serotonin transporter (SERT) gene polymorphism and idiopathic pulmonary arterial hypertension: a meta-analysis and review of the literature. Metabolism: clinical and experimental. vol 62. issue 12. 2014-01-08. PMID:24075737. |
serotonin transporter (sert) protein, whose genes can have two allelic forms, namely long (l) and short (s), is suspected to be related to ipah risk. |
2014-01-08 |
2023-08-12 |
Not clear |
| Vibe Gedsoe Frokjaer, David Erritzoe, Klaus Kähler Holst, Peter Steen Jensen, Peter Mondrup Rasmussen, Patrick Macdonald Fisher, William Baaré, Kathrine Skak Madsen, Jacob Madsen, Claus Svarer, Gitte Moos Knudse. Prefrontal serotonin transporter availability is positively associated with the cortisol awakening response. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 4. 2014-01-06. PMID:22732516. |
individuals carrying the low-expressing variants (s and lg) of the 5-httlpr promoter polymorphism of the serotonin transporter (sert) gene are at higher risk for developing mood disorders when exposed to severe stress and display higher cortisol responses when exposed to psychosocial stressors relative to high expressing 5-httlpr variants. |
2014-01-06 |
2023-08-12 |
Not clear |
| Cécile Bétry, Alan L Pehrson, Adeline Etiévant, Bjarke Ebert, Connie Sánchez, Nasser Haddjer. The rapid recovery of 5-HT cell firing induced by the antidepressant vortioxetine involves 5-HT(3) receptor antagonism. The international journal of neuropsychopharmacology. vol 16. issue 5. 2014-01-03. PMID:23089374. |
here, we report the effects of the multi-modal antidepressant vortioxetine (lu aa21004), a 5-ht(3) and 5-ht(7) receptor antagonist, 5-ht(1b) receptor partial agonist, 5-ht(1a) receptor agonist and 5-ht transporter (sert) inhibitor, on rat 5-ht neurotransmission. |
2014-01-03 |
2023-08-12 |
rat |
| Cécile Bétry, Alan L Pehrson, Adeline Etiévant, Bjarke Ebert, Connie Sánchez, Nasser Haddjer. The rapid recovery of 5-HT cell firing induced by the antidepressant vortioxetine involves 5-HT(3) receptor antagonism. The international journal of neuropsychopharmacology. vol 16. issue 5. 2014-01-03. PMID:23089374. |
using ex-vivo autoradiography, we correlated sert occupancy and presumed 5-ht firing activity. |
2014-01-03 |
2023-08-12 |
rat |
| Cécile Bétry, Alan L Pehrson, Adeline Etiévant, Bjarke Ebert, Connie Sánchez, Nasser Haddjer. The rapid recovery of 5-HT cell firing induced by the antidepressant vortioxetine involves 5-HT(3) receptor antagonism. The international journal of neuropsychopharmacology. vol 16. issue 5. 2014-01-03. PMID:23089374. |
this is at least partly due to 5-ht(3) receptor antagonism of vortioxetine in association with its reduced sert occupancy. |
2014-01-03 |
2023-08-12 |
rat |
| Mari Gabrielsen, Karol Wołosewicz, Anna Zawadzka, Jerzy Kossakowski, Gabriel Nowak, Małgorzata Wolak, Katarzyna Stachowicz, Agata Siwek, Aina W Ravna, Irina Kufareva, Lech Kozerski, Elżbieta Bednarek, Jerzy Sitkowski, Wojciech Bocian, Ruben Abagyan, Andrzej J Bojarski, Ingebrigt Sylte, Zdzisław Chilmonczy. Synthesis, antidepressant evaluation and docking studies of long-chain alkylnitroquipazines as serotonin transporter inhibitors. Chemical biology & drug design. vol 81. issue 6. 2014-01-02. PMID:23574807. |
twelve alkyl analogues (1-12) of the high-affinity serotonin transporter (sert) inhibitor 6-nitroquipazine (6-nq) were synthesized and studied using in vitro radioligand competition binding assays to determine their binding affinity (ki ). |
2014-01-02 |
2023-08-12 |
mouse |
| Yuan-Hwa Chou, Chun-Lung Lin, Shyh-Jen Wang, Jiing-Feng Lirng, Kai-Chun Yang, Alice Chien Chang, Mei-Hsiu Lia. Aggression in bipolar II disorder and its relation to the serotonin transporter. Journal of affective disorders. vol 147. issue 1-3. 2013-12-30. PMID:23123132. |
the objective of this study was to determine whether there is an association between aggression and the availability of the serotonin transporter (sert) in euthymic bd ii patients. |
2013-12-30 |
2023-08-12 |
human |
| Pei-Shen Ho, Kellen Kai-Jen Ho, Wen-Sheng Huang, Che-Hung Yen, Mei-Chen Shih, Lie-Hang Shen, Kuo-Hsing Ma, San-Yuan Huan. Association study of serotonin transporter availability and SLC6A4 gene polymorphisms in patients with major depression. Psychiatry research. vol 212. issue 3. 2013-12-30. PMID:23149035. |
the serotonin transporter (sert) is hypothesized to be an important component of the pathophysiology of major depression (md). |
2013-12-30 |
2023-08-12 |
Not clear |
| Pei-Shen Ho, Kellen Kai-Jen Ho, Wen-Sheng Huang, Che-Hung Yen, Mei-Chen Shih, Lie-Hang Shen, Kuo-Hsing Ma, San-Yuan Huan. Association study of serotonin transporter availability and SLC6A4 gene polymorphisms in patients with major depression. Psychiatry research. vol 212. issue 3. 2013-12-30. PMID:23149035. |
the effects of three genetic variants (rs25531, rs6354 and stin2) of the serotonin transporter gene (slc6a4) on sert availability were also investigated. |
2013-12-30 |
2023-08-12 |
Not clear |
| J J Galligan, B A Patel, S P Schneider, H Wang, H Zhao, M Novotny, X Bian, R Kabeer, D Fried, G M Swai. Visceral hypersensitivity in female but not in male serotonin transporter knockout rats. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. vol 25. issue 6. 2013-12-30. PMID:23594365. |
serotonin signaling, including reduced serotonin transporter (sert) expression, may be disrupted in ibs patients. |
2013-12-30 |
2023-08-12 |
rat |
| M G Sánchez, M Morissette, T Di Paol. Oestradiol modulation of serotonin reuptake transporter and serotonin metabolism in the brain of monkeys. Journal of neuroendocrinology. vol 25. issue 6. 2013-12-26. PMID:23414342. |
the present study evaluated 5-ht reuptake transporter (sert) and 5-ht metabolism in these brain regions in response to 1-month treatment with 17β-oestradiol in short-term (1 month) ovariectomised (ovx) monkeys (macaca fascicularis). |
2013-12-26 |
2023-08-12 |
monkey |
| Seyed Khosrow Tayebati, Daniele Tomassoni, Innocent Ejike Nwankwo, Antonio Di Stefano, Piera Sozio, Laura Serafina Cerasa, Francesco Ament. Modulation of monoaminergic transporters by choline-containing phospholipids in rat brain. CNS & neurological disorders drug targets. vol 12. issue 1. 2013-12-23. PMID:23244432. |
the present study was designed to assess the influence of treatment for 7 days with choline-equivalent doses (cdp-choline: 325 mg/kg/day; gpc: 150 mg/kg/day) of these compounds on brain dopamine (da), and serotonin (5-ht) levels and on da plasma membrane transporter (dat), vesicular monoamine transporters (vmat1 and vmat2), serotonin transporter (sert), and norepinephrine transporter (net) in the rat. |
2013-12-23 |
2023-08-12 |
rat |
| Cynthia L Bethea, Kenny Phu, Arubala P Reddy, Judy L Camero. The effect of short-term stress on serotonin gene expression in high and low resilient macaques. Progress in neuro-psychopharmacology & biological psychiatry. vol 44. 2013-12-18. PMID:23357537. |
tryptophan hydroxylase 2 (tph2), the serotonin reuptake transporter (sert), and the 5ht1a autoreceptor mrnas expression were determined at 4 morphological levels of the dorsal raphe nucleus with in situ hybridization (ish) using digoxigenin-incorporated riboprobes. |
2013-12-18 |
2023-08-12 |
monkey |
| Wenqiang Li, Yongfeng Yang, Juntang Lin, Shuai Wang, Jingyuan Zhao, Ge Yang, Xiujuan Wang, Minli Ding, Hongxing Zhang, Luxian L. Association of serotonin transporter gene (SLC6A4) polymorphisms with schizophrenia susceptibility and symptoms in a Chinese-Han population. Progress in neuro-psychopharmacology & biological psychiatry. vol 44. 2013-12-18. PMID:23583772. |
the serotonin transporter (sert), encoded by solute carrier family 6 member 4 (slc6a4), regulates synaptic concentrations of serotonin and thereby strongly influences perception, mood, emotion, behavior, and cognition, all of which are severely disturbed in sz. |
2013-12-18 |
2023-08-12 |
human |
| Su-Xia Li, Jing Li, Xue Wang, Zu-Gui Peng, Wei-Hong Kuang, Ming-Sheng Huan. [Long-term neurotoxic effects of MDMA result in cortical and hippocampal structural changes]. Sheng li xue bao : [Acta physiologica Sinica]. vol 58. issue 1. 2013-12-12. PMID:16489401. |
thirty-two weeks after administering mdma, the expression of serotonin transporter (sert) mrna and diazepam binding inhibitor (dbi) mrna was detected by in situ hybridization. |
2013-12-12 |
2023-08-12 |
rat |
| Karin Eva Koopman, Jan Booij, Eric Fliers, Mireille Johanna Serlie, Susanne Eva la Fleu. Diet-induced changes in the Lean Brain: Hypercaloric high-fat-high-sugar snacking decreases serotonin transporters in the human hypothalamic region. Molecular metabolism. vol 2. issue 4. 2013-12-11. PMID:24327957. |
to determine whether obesogenic eating habits result in reduced serotonin transporter (sert)-binding in the human hypothalamic region, we included 25 lean, male subjects who followed a 6-week-hypercaloric diet, which were high-fat-high-sugar (hfhs) or high-sugar (hs) with increased meal size or -frequency (=snacking pattern). |
2013-12-11 |
2023-08-12 |
human |
| Anna Czopek, Marcin Kołaczkowski, Adam Bucki, Hanna Byrtus, Maciej Pawłowski, Agata Siwek, Andrzej J Bojarski, Marek Bednarski, Dagmara Wróbel, Anna Wesołowsk. Novel mannich bases, 5-arylimidazolidine-2,4-dione derivatives with dual 5-HT(1A) receptor and serotonin transporter affinity. Archiv der Pharmazie. vol 346. issue 2. 2013-12-09. PMID:23288448. |
a computer aided ligand design study of imidazolidine-2,4-dione derivatives was conducted in order to obtain compounds with dual 5-ht(1a) receptor and serotonin transporter (sert) affinity. |
2013-12-09 |
2023-08-12 |
mouse |