| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S R Suwijn, H W Berendse, C V M Verschuur, R M A de Bie, J Booi. Serotonin transporter availability in early stage Parkinson's disease and multiple system atrophy. ISRN neurology. vol 2014. 2014-04-02. PMID:24693450. |
previous studies have shown that midbrain serotonin transporter (sert) availability in patients with established msa was significantly lower compared to pd. |
2014-04-02 |
2023-08-13 |
Not clear |
| Laetitia Lemoine, Brian P Lieberman, Karl Ploessl, Pinguan Zheng, Hank F Kun. Characterization of FlipIDAM as a SERT-selective SPECT imaging agent. Nuclear medicine and biology. vol 40. issue 7. 2014-04-01. PMID:23856117. |
biological evaluation of ([(125)i]4), a new single-photon emission computed tomography (spect) radioligand for imaging the serotonin transporter (sert) which displayed improved in vivo kinetics for mapping sert binding sites in the brain. |
2014-04-01 |
2023-08-12 |
Not clear |
| Pau Celada, Analía Bortolozzi, Francesc Artiga. Serotonin 5-HT1A receptors as targets for agents to treat psychiatric disorders: rationale and current status of research. CNS drugs. vol 27. issue 9. 2014-03-19. PMID:23757185. |
moreover, the indirect activation of presynaptic 5-ht1a-rs by ssris/snris reduces 5-ht neuron activity and terminal 5-ht release, thus opposing the elevation of extracellular 5-ht produced by blockade of the serotonin transporter (sert) in the forebrain. |
2014-03-19 |
2023-08-12 |
mouse |
| Ashwini K Banala, Peng Zhang, Per Plenge, George Cyriac, Theresa Kopajtic, Jonathan L Katz, Claus Juul Loland, Amy Hauck Newma. Design and synthesis of 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile (citalopram) analogues as novel probes for the serotonin transporter S1 and S2 binding sites. Journal of medicinal chemistry. vol 56. issue 23. 2014-03-04. PMID:24237160. |
the serotonin transporter (sert) is the primary target for antidepressant drugs. |
2014-03-04 |
2023-08-12 |
Not clear |
| Maria Gabriela Sánchez, Marc Morissette, Thérèse Di Paol. Estradiol and brain serotonin reuptake transporter in long-term ovariectomized parkinsonian monkeys. Progress in neuro-psychopharmacology & biological psychiatry. vol 45. 2014-02-26. PMID:23719069. |
this study evaluated the effect of a one month 17β-estradiol treatment on brain serotonin (5-ht) reuptake transporter (sert) in long-term ovariectomized (ovx) female monkeys (macaca fascicularis) bearing a unilateral lesion with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) injected directly into the left substantia nigra modeling parkinson disease (pd). |
2014-02-26 |
2023-08-12 |
monkey |
| Maria Gabriela Sánchez, Marc Morissette, Thérèse Di Paol. Estradiol and brain serotonin reuptake transporter in long-term ovariectomized parkinsonian monkeys. Progress in neuro-psychopharmacology & biological psychiatry. vol 45. 2014-02-26. PMID:23719069. |
positive correlations between [(3)h]citalopram specific binding and 5-ht as well as 5-hiaa concentrations (reported previously) were obtained in the caudate nucleus and putamen and a negative correlation between sert binding and 5-hiaa/5-ht concentration ratio suggesting mptp lesion-induced 5-ht neuronal loss and lower 5-ht neurotransmission controlling and decreasing sert for homeostasis. |
2014-02-26 |
2023-08-12 |
monkey |
| Silvina L Diaz, Nicolas Narboux-Nême, Sara Trowbridge, Sophie Scotto-Lomassese, Felix B Kleine Borgmann, Sebastian Jessberger, Bruno Giros, Luc Maroteaux, Evan Deneris, Patricia Gaspa. Paradoxical increase in survival of newborn neurons in the dentate gyrus of mice with constitutive depletion of serotonin. The European journal of neuroscience. vol 38. issue 5. 2014-02-26. PMID:23841816. |
here, we analysed two genetic models of 5-ht depletion, the pet1(-/-) and the vmat2(f/f) ; sert(cre/+) mice, which have, respectively, 80 and 95% reductions in hippocampal 5-ht. |
2014-02-26 |
2023-08-12 |
mouse |
| Jolanta Dorszewska, Michal Prendecki, Anna Oczkowska, Agata Rozycka, Margarita Lianeri, Wojciech Kozubsk. Polymorphism of the COMT, MAO, DAT, NET and 5-HTT Genes, and Biogenic Amines in Parkinson's Disease. Current genomics. vol 14. issue 8. 2014-02-17. PMID:24532984. |
however, the monoamine transporters for da, ne, and 5-ht namely dat, net, and sert, respectively regulate the monoamine concentration. |
2014-02-17 |
2023-08-12 |
Not clear |
| Magdy El-Salhy, Ingvild Wendelbo, Doris Gunderse. Serotonin and serotonin transporter in the rectum of patients with irritable bowel disease. Molecular medicine reports. vol 8. issue 2. 2014-02-13. PMID:23778763. |
the present study was undertaken to investigate the immunoreactivity intensity of serotonin and serotonin‑selective reuptake transporter (sert) in the rectum of ibs patients. |
2014-02-13 |
2023-08-12 |
human |
| Magdy El-Salhy, Ingvild Wendelbo, Doris Gunderse. Serotonin and serotonin transporter in the rectum of patients with irritable bowel disease. Molecular medicine reports. vol 8. issue 2. 2014-02-13. PMID:23778763. |
rectal biopsy specimens were immunostained using the avidin‑biotin complex method for serotonin and sert. |
2014-02-13 |
2023-08-12 |
human |
| Francesca Calabrese, Gianluigi Guidotti, Anthonieke Middelman, Giorgio Racagni, Judith Homberg, Marco A Riv. Lack of serotonin transporter alters BDNF expression in the rat brain during early postnatal development. Molecular neurobiology. vol 48. issue 1. 2014-02-12. PMID:23564488. |
accordingly, it has been demonstrated that genetic deletion of the serotonin transporter (sert) in rodents leads to an anxious and depressive phenotype, which is also associated with reduced neuronal plasticity. |
2014-02-12 |
2023-08-12 |
rat |
| Sandhya Kortagere, Andreia Cristina Karklin Fontana, Deja Renée Rose, Ole Valente Mortense. Identification of an allosteric modulator of the serotonin transporter with novel mechanism of action. Neuropharmacology. vol 72. 2014-02-11. PMID:23632081. |
in functional transport assays, we found that one of the identified molecules, atm7, increased the reuptake of serotonin, possibly by facilitating the interaction of serotonin with transport-ready conformations of sert when concentrations of serotonin were low and rate limiting. |
2014-02-11 |
2023-08-12 |
Not clear |
| Chihiro Yokoyama, Akihiro Kawasaki, Takuya Hayashi, Hirotaka Ono. Linkage between the midline cortical serotonergic system and social behavior traits: positron emission tomography studies of common marmosets. Cerebral cortex (New York, N.Y. : 1991). vol 23. issue 9. 2014-02-10. PMID:22791806. |
to determine the location and serotonin function of brain areas involved in social behavior traits, we tested serotonin transporter (sert) binding and neural activity linked with the social behaviors of common marmosets with positron emission tomography using [(11)c]-3-amino-4-(2-dimetylaminomethyl-phenylsulfanyl)-benzonitrile and [(18)f]fluorodeoxyglucose, respectively. |
2014-02-10 |
2023-08-12 |
Not clear |
| Francesca Zoratto, Amanda L Tringle, Giancarlo Bellenchi, Luisa Speranza, Domenica Travaglini, Umberto di Porzio, Carla Perrone-Capano, Giovanni Laviola, Jean-Luc Dreyer, Walter Adrian. Impulsivity and home-cage activity are decreased by lentivirus-mediated silencing of serotonin transporter in the rat hippocampus. Neuroscience letters. vol 548. 2014-02-07. PMID:23769733. |
mutations in the serotonin transporter (sert) gene have been associated with susceptibility towards the development of several psychiatric disorders, both in humans and animal models. |
2014-02-07 |
2023-08-12 |
rat |
| Mika Naganawa, Nabeel Nabulsi, Beata Planeta, Jean-Dominique Gallezot, Shu-Fei Lin, Soheila Najafzadeh, Wendol Williams, Jim Ropchan, David Labaree, Alexander Neumeister, Yiyun Huang, Richard E Carso. Tracer kinetic modeling of [(11)C]AFM, a new PET imaging agent for the serotonin transporter. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 33. issue 12. 2014-02-03. PMID:23921898. |
[(11)c]afm, or [(11)c]2-[2-(dimethylaminomethyl)phenylthio]-5-fluoromethylphenylamine, is a new positron emission tomography (pet) radioligand with high affinity and selectivity for the serotonin transporter (sert). |
2014-02-03 |
2023-08-12 |
human |
| Abraham Martín, Boguslaw Szczupak, Vanessa Gómez-Vallejo, Sandra Plaza, Daniel Padró, Ainhoa Cano, Jordi Llo. PET imaging of serotoninergic neurotransmission with [(11)C]DASB and [(18)F]altanserin after focal cerebral ischemia in rats. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 33. issue 12. 2014-02-03. PMID:23982048. |
in the ischemic territory, pet with [(11)c]dasb and [(18)f]altanserin showed a dramatic decline in serotonin transporter (sert) and 5-ht2a binding potential in the cortex and striatum after cerebral ischemia. |
2014-02-03 |
2023-08-12 |
rat |
| Megan C Riddle, Morgan C McKenna, Yone J Yoon, Siobhan S Pattwell, Patricia Mae G Santos, B J Casey, Charles E Glat. Caloric restriction enhances fear extinction learning in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 6. 2014-01-21. PMID:23303073. |
wild type and serotonin transporter (sert) knockout mice underwent cr for 7 days leading to significant weight loss. |
2014-01-21 |
2023-08-12 |
mouse |
| Nora S Vyas, Neva H Patel, Peter Herscovitch, Basant K Puri, Rupert Lanzenberge. Recent developments in neurochemical imaging in schizophrenia: an update. Current medicinal chemistry. vol 20. issue 3. 2014-01-17. PMID:23157626. |
recent development of selective radiotracers allow imaging of the serotonin transporter (sert) using positron emission tomography (pet) with selective tracers such as [(11)c]dasb. |
2014-01-17 |
2023-08-12 |
human |
| Alessia Luoni, Sjoerd Hulsken, Greta Cazzaniga, Giorgio Racagni, Judith R Homberg, Marco A Riv. Behavioural and neuroplastic properties of chronic lurasidone treatment in serotonin transporter knockout rats. The international journal of neuropsychopharmacology. vol 16. issue 6. 2014-01-15. PMID:23164505. |
the aim of this study was thus to establish the ability of lurasidone, a novel sga characterized by a multi-receptor signature, to modulate behavioural and molecular defects associated with a genetic model of impaired emotional control, namely serotonin transporter knockout (sert ko) rats. |
2014-01-15 |
2023-08-12 |
rat |
| Hanneke E M den Ouden, Nathaniel D Daw, Guillén Fernandez, Joris A Elshout, Mark Rijpkema, Martine Hoogman, Barbara Franke, Roshan Cool. Dissociable effects of dopamine and serotonin on reversal learning. Neuron. vol 80. issue 4. 2014-01-15. PMID:24267657. |
we studied the role of these neurotransmitters in probabilistic reversal learning in nearly 700 individuals as a function of two polymorphisms in the genes encoding the serotonin and dopamine transporters (sert: 5httlpr plus rs25531; dat1 3'utr vntr). |
2014-01-15 |
2023-08-12 |
Not clear |