| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marc Udina, José Moreno-España, Ricard Navinés, Dolors Giménez, Klaus Langohr, Mònica Gratacòs, Lucile Capuron, Rafael de la Torre, Ricard Solà, Rocío Martín-Santo. Serotonin and interleukin-6: the role of genetic polymorphisms in IFN-induced neuropsychiatric symptoms. Psychoneuroendocrinology. vol 38. issue 9. 2014-05-14. PMID:23571152. |
the aim of the present study was to investigate the association between ifn-induced depression, anxiety and fatigue and functional genetic variants at the interleukin-6 gene (il-6) and serotonin transporter gene (sert). |
2014-05-14 |
2023-08-12 |
Not clear |
| Andrew C Parrot. MDMA, serotonergic neurotoxicity, and the diverse functional deficits of recreational 'Ecstasy' users. Neuroscience and biobehavioral reviews. vol 37. issue 8. 2014-05-08. PMID:23660456. |
serotonergic neurotoxicity following mdma is well-established in laboratory animals, and neuroimaging studies have found lower serotonin transporter (sert) binding in abstinent ecstasy/mdma users. |
2014-05-08 |
2023-08-12 |
Not clear |
| Jay D Amsterdam, Andrew B Newberg, Cory F Newman, Justine Shults, Nancy Wintering, Irene Soelle. Change over time in brain serotonin transporter binding in major depression: effects of therapy measured with [(123) I]-ADAM SPECT. Journal of neuroimaging : official journal of the American Society of Neuroimaging. vol 23. issue 4. 2014-05-05. PMID:23751132. |
several studies have reported low brain serotonin transporter (sert) binding in individuals with major depression. |
2014-05-05 |
2023-08-12 |
human |
| Javier A Bravo, Timothy G Dinan, John F Crya. Early-life stress induces persistent alterations in 5-HT1A receptor and serotonin transporter mRNA expression in the adult rat brain. Frontiers in molecular neuroscience. vol 7. 2014-04-30. PMID:24782706. |
we hypothesize that this alteration may be caused by differences in 5-ht1a receptor and serotonin transporter (sert) mrna expression in brain areas involved in the control of emotions, memory, and fear as well as in regions controlling the central serotonergic tone. |
2014-04-30 |
2023-08-13 |
rat |
| Nashwa Jarka. Fluorinated diaryl sulfides. Current topics in medicinal chemistry. vol 13. issue 8. 2014-04-28. PMID:23590166. |
diaryl sulfides also known as diphenyl sulfides, phenylthiobenzylamines, and biphenylthiols are a class of compounds with phenylthiophenyl scaffold that have been validated as biomarkers to label the brain serotonin transporter (sert), in vivo. |
2014-04-28 |
2023-08-12 |
human |
| Stal Saurav Shrestha, Eric E Nelson, Jeih-San Liow, Robert Gladding, Chul Hyoung Lyoo, Pam L Noble, Cheryl Morse, Ioline D Henter, Jeremy Kruger, Bo Zhang, Stephen J Suomi, Per Svenningsson, Victor W Pike, James T Winslow, Ellen Leibenluft, Daniel S Pine, Robert B Inni. Fluoxetine administered to juvenile monkeys: effects on the serotonin transporter and behavior. The American journal of psychiatry. vol 171. issue 3. 2014-04-24. PMID:24480874. |
this study examined the long-term effects of fluoxetine administered to juvenile rhesus monkeys who, as young adults, were imaged with positron emission tomography for two serotonergic markers: serotonin transporter (sert) and serotonin 1a (5-ht1a) receptor. |
2014-04-24 |
2023-08-12 |
human |
| Linda D Simmler, Anna Rickli, York Schramm, Marius C Hoener, Matthias E Liecht. Pharmacological profiles of aminoindanes, piperazines, and pipradrol derivatives. Biochemical pharmacology. vol 88. issue 2. 2014-04-22. PMID:24486525. |
we investigated norepinephrine (ne), dopamine (da), and serotonin (5-hydroxytryptamine [5-ht]) uptake inhibition using human embryonic kidney 293 (hek 293) cells that express the respective human monoamine transporters (net, dat, and sert). |
2014-04-22 |
2023-08-12 |
human |
| Linda D Simmler, Anna Rickli, York Schramm, Marius C Hoener, Matthias E Liecht. Pharmacological profiles of aminoindanes, piperazines, and pipradrol derivatives. Biochemical pharmacology. vol 88. issue 2. 2014-04-22. PMID:24486525. |
5-iai and mdai preferentially inhibited the sert and net and released 5-ht. |
2014-04-22 |
2023-08-12 |
human |
| Alan L Pehrson, Thomas Cremers, Cecile Bétry, Marieke G C van der Hart, Laerke Jørgensen, Mathias Madsen, Nasser Haddjeri, Bjarke Ebert, Connie Sanche. Lu AA21004, a novel multimodal antidepressant, produces regionally selective increases of multiple neurotransmitters--a rat microdialysis and electrophysiology study. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 2. 2014-04-21. PMID:22612991. |
preclinical research suggests that 5-ht receptor subtypes, including 5-ht1a, 5-ht1b, 5-ht3, and 5-ht7 receptors as well as the 5-ht transporter (sert), may have important roles in treating depression. |
2014-04-21 |
2023-08-12 |
rat |
| Alan L Pehrson, Thomas Cremers, Cecile Bétry, Marieke G C van der Hart, Laerke Jørgensen, Mathias Madsen, Nasser Haddjeri, Bjarke Ebert, Connie Sanche. Lu AA21004, a novel multimodal antidepressant, produces regionally selective increases of multiple neurotransmitters--a rat microdialysis and electrophysiology study. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 2. 2014-04-21. PMID:22612991. |
furthermore, mpfc 5-ht levels were increased at low sert occupancy levels. |
2014-04-21 |
2023-08-12 |
rat |
| Samira Daniali, Zahra Madjd, Ali Shahbazi, Somayeh Niknazar, Delavar Shahbazzade. Chronic Ritalin administration during adulthood increases serotonin pool in rat medial frontal cortex. Iranian biomedical journal. vol 17. issue 3. 2014-04-17. PMID:23748891. |
this study was undertaken to find ritalin effect on serotonin transporter (sert) density in medial frontal cortex (mfc) of mature rat. |
2014-04-17 |
2023-08-12 |
rat |
| Oluyomi M Okunola-Bakare, Jianjing Cao, Theresa Kopajtic, Jonathan L Katz, Claus J Loland, Lei Shi, Amy Hauck Newma. Elucidation of structural elements for selectivity across monoamine transporters: novel 2-[(diphenylmethyl)sulfinyl]acetamide (modafinil) analogues. Journal of medicinal chemistry. vol 57. issue 3. 2014-04-15. PMID:24494745. |
halogen substitution of the diphenyl rings of (±)-1 gave several amide analogues with improved binding affinity for dat and robust selectivity over the serotonin transporter (sert), whereas affinity improved at sert over dat for the p-halo-substituted amine analogues. |
2014-04-15 |
2023-08-12 |
Not clear |
| Yong-Jin Wu, Huan He, Robert Bertekap, Ryan Westphal, Snjezana Lelas, Amy Newton, Tanya Wallace, Matthew Taber, Carl Davis, John E Macor, Joanne Bronso. Discovery of disubstituted piperidines and homopiperidines as potent dual NK1 receptor antagonists-serotonin reuptake transporter inhibitors for the treatment of depression. Bioorganic & medicinal chemistry. vol 21. issue 8. 2014-04-08. PMID:23477943. |
this report describes the synthesis, structure-activity relationships and activity of piperidine, homopiperidine, and azocane derivatives combining nk1 receptor (nk1r) antagonism and serotonin reuptake transporter (sert) inhibition. |
2014-04-08 |
2023-08-12 |
Not clear |
| Craig P Motbey, Kelly J Clemens, Nadine Apetz, Adam R Winstock, John Ramsey, Kong M Li, Naomi Wyatt, Paul D Callaghan, Michael T Bowen, Jennifer L Cornish, Iain S McGrego. High levels of intravenous mephedrone (4-methylmethcathinone) self-administration in rats: neural consequences and comparison with methamphetamine. Journal of psychopharmacology (Oxford, England). vol 27. issue 9. 2014-04-08. PMID:23739178. |
brains were analyzed ex vivo for striatal serotonin (5-ht) and dopamine (da) levels and metabolites, while autoradiography assessed changes in the regional density of 5-ht and serotonin transporter (sert) and da transporter (dat) and induction of the inflammation marker translocator protein (tspo). |
2014-04-08 |
2023-08-12 |
rat |
| Gino Giannaccini, Laura Betti, Lionella Palego, Alessandro Marsili, Ferruccio Santini, Caterina Pelosini, Laura Fabbrini, Lara Schmid, Laura Giusti, Margherita Maffei, Mario Lanza, Mario Cristofaro, Stefano Baroni, Mauro Mauri, Paolo Vitti, Paola Fierabracci, Antonio Lucacchin. The expression of platelet serotonin transporter (SERT) in human obesity. BMC neuroscience. vol 14. 2014-04-07. PMID:24138674. |
the expression of platelet serotonin transporter (sert) in human obesity. |
2014-04-07 |
2023-08-12 |
human |
| Gino Giannaccini, Laura Betti, Lionella Palego, Alessandro Marsili, Ferruccio Santini, Caterina Pelosini, Laura Fabbrini, Lara Schmid, Laura Giusti, Margherita Maffei, Mario Lanza, Mario Cristofaro, Stefano Baroni, Mauro Mauri, Paolo Vitti, Paola Fierabracci, Antonio Lucacchin. The expression of platelet serotonin transporter (SERT) in human obesity. BMC neuroscience. vol 14. 2014-04-07. PMID:24138674. |
since platelets are a suitable peripheral model to study 5-ht transport, metabolism and release, we herein evaluated the expression of the platelet 5-ht re-uptake system (sert) by [3h]-paroxetine binding assay. |
2014-04-07 |
2023-08-12 |
human |
| Maarika Liik, Malle Paris, Liina Vahter, Katrin Gross-Paju, Sulev Haldr. 123I-ADAM SPET imaging of serotonin transporter in patients with epilepsy and comorbid depression. BMC neurology. vol 13. 2014-04-04. PMID:24341899. |
purpose of the study was to investigate alterations in midbrain serotonin transporter (sert) binding in patients with epilepsy and symptoms of depression compared to patients with epilepsy with no symptoms of depression. |
2014-04-04 |
2023-08-12 |
Not clear |
| I Ouellet-Morin, C C Y Wong, A Danese, C M Pariante, A S Papadopoulos, J Mill, L Arseneaul. Increased serotonin transporter gene (SERT) DNA methylation is associated with bullying victimization and blunted cortisol response to stress in childhood: a longitudinal study of discordant monozygotic twins. Psychological medicine. vol 43. issue 9. 2014-04-03. PMID:23217646. |
increased serotonin transporter gene (sert) dna methylation is associated with bullying victimization and blunted cortisol response to stress in childhood: a longitudinal study of discordant monozygotic twins. |
2014-04-03 |
2023-08-12 |
Not clear |
| I Ouellet-Morin, C C Y Wong, A Danese, C M Pariante, A S Papadopoulos, J Mill, L Arseneaul. Increased serotonin transporter gene (SERT) DNA methylation is associated with bullying victimization and blunted cortisol response to stress in childhood: a longitudinal study of discordant monozygotic twins. Psychological medicine. vol 43. issue 9. 2014-04-03. PMID:23217646. |
method we tested whether bullying victimization influenced serotonin transporter gene (sert) dna methylation using a discordant monozygotic (mz) twin design. |
2014-04-03 |
2023-08-12 |
Not clear |
| Pablo R Moya, Jens R Wendland, Liza M Rubenstein, Kiara R Timpano, Gary A Heiman, Jay A Tischfield, Robert A King, Anne M Andrews, Samanda Ramamoorthy, Francis J McMahon, Dennis L Murph. Common and rare alleles of the serotonin transporter gene, SLC6A4, associated with Tourette's disorder. Movement disorders : official journal of the Movement Disorder Society. vol 28. issue 9. 2014-04-02. PMID:23630162. |
to evaluate the hypothesis that functionally over-expressing alleles of the serotonin transporter (sert) gene (solute carrier family 6, member 4, slc6a4) are present in tourette's disorder (td), just as we previously observed in obsessive compulsive disorder (ocd), we evaluated td probands (n = 151) and controls (n = 858). |
2014-04-02 |
2023-08-12 |
Not clear |