| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wenlu Pan, Kexin Lyu, Hongzheng Zhang, Cuixian Li, Peng Chen, Ming Ying, Fangyi Chen, Jie Tan. Attenuation of auditory mismatch negativity in serotonin transporter knockout mice with anxiety-related behaviors. Behavioural brain research. vol 379. 2021-05-03. PMID:31783087. |
serotonin transporter (sert) is a potential target of ssris. |
2021-05-03 |
2023-08-13 |
mouse |
| Janak R Awasthi, Kota Tamada, Eric T N Overton, Toru Takum. Development of serotonergic projections to the suprachiasmatic nucleus in the mouse brain. Neuroscience letters. vol 739. 2021-04-30. PMID:33132178. |
here, we utilize transgenic mice expressing gfp under the serotonin transporter (sert) promoter to subserve our developmental mapping study. |
2021-04-30 |
2023-08-13 |
mouse |
| Marco Niello, Daniela Cintulová, Philip Raithmayr, Marion Holy, Kathrin Jäntsch, Claire Colas, Gerhard F Ecker, Harald H Sitte, Marko D Mihovilovi. Effects of Hydroxylated Mephedrone Metabolites on Monoamine Transporter Activity Frontiers in pharmacology. vol 12. 2021-04-28. PMID:33897439. |
it elicits the release of monoamines via the high affinity transporters for dopamine (dat), norepinephrine (net) and serotonin (sert). |
2021-04-28 |
2023-08-13 |
Not clear |
| Kei Taguchi, Masayuki Kaneko, Serika Motoike, Kana Harada, Izumi Hide, Shigeru Tanaka, Norio Saka. Role of the E3 ubiquitin ligase HRD1 in the regulation of serotonin transporter function. Biochemical and biophysical research communications. vol 534. 2021-04-19. PMID:33243462. |
to elucidate the regulation of serotonin transporter (sert) function via its membrane trafficking, we investigated the involvement of the ubiquitin e3 ligase hrd1 (hmg-coa reductase degradation protein), which participates in endoplasmic reticulum (er)-associated degradation (erad), in the functional regulation of sert. |
2021-04-19 |
2023-08-13 |
Not clear |
| Qiang Lu, Chiaki Murakami, Yuki Murakami, Fumi Hoshino, Maho Asami, Takako Usuki, Hiromichi Sakai, Fumio Sakan. 1-Stearoyl-2-docosahexaenoyl-phosphatidic acid interacts with and activates Praja-1, the E3 ubiquitin ligase acting on the serotonin transporter in the brain. FEBS letters. vol 594. issue 11. 2021-04-16. PMID:32134507. |
serotonin transporter (sert) is involved in serotonergic system regulation and in the pathophysiology/therapeutics of serotonin-/sert-related diseases such as obsessive-compulsive disorder, depression, autism, and schizophrenia. |
2021-04-16 |
2023-08-13 |
mouse |
| Jonathan A Coleman, Vikas Navratna, Daniele Antermite, Dongxue Yang, James A Bull, Eric Gouau. Chemical and structural investigation of the paroxetine-human serotonin transporter complex. eLife. vol 9. 2021-04-16. PMID:32618269. |
antidepressants target the serotonin transporter (sert) by inhibiting serotonin reuptake. |
2021-04-16 |
2023-08-13 |
Not clear |
| Jonathan A Coleman, Vikas Navratna, Daniele Antermite, Dongxue Yang, James A Bull, Eric Gouau. Chemical and structural investigation of the paroxetine-human serotonin transporter complex. eLife. vol 9. 2021-04-16. PMID:32618269. |
these studies provide mutually consistent insights into how paroxetine and its analogues bind to the central substrate-binding site of sert, stabilize the outward-open conformation, and inhibit serotonin transport. |
2021-04-16 |
2023-08-13 |
Not clear |
| Carmen M Deveau, Eric Rodriguez, Allen Schroering, Bryan K Yamamot. Serotonin transporter regulation by cholesterol-independent lipid signaling. Biochemical pharmacology. vol 183. 2021-04-15. PMID:33245902. |
serotonin neurotransmission is largely governed by the regulation of the serotonin transporter (sert). |
2021-04-15 |
2023-08-13 |
Not clear |
| Carmen M Deveau, Eric Rodriguez, Allen Schroering, Bryan K Yamamot. Serotonin transporter regulation by cholesterol-independent lipid signaling. Biochemical pharmacology. vol 183. 2021-04-15. PMID:33245902. |
simvastatin lowered the km without changing vmax for 5-ht or sert distribution to the plasma membrane. |
2021-04-15 |
2023-08-13 |
Not clear |
| Carina Meinke, Meagan A Quinlan, Krista C Paffenroth, Fiona E Harrison, Cristina Fenollar-Ferrer, Rania M Katamish, Isabel Stillman, Sammanda Ramamoorthy, Randy D Blakel. Serotonin Transporter Ala276 Mouse: Novel Model to Assess the Neurochemical and Behavioral Impact of Thr276 Phosphorylation In Vivo. Neurochemical research. 2021-04-08. PMID:33830406. |
the serotonin (5-ht) transporter (sert) is a key regulator of 5-ht signaling and is a major target for antidepressants and psychostimulants. |
2021-04-08 |
2023-08-13 |
mouse |
| Carina Meinke, Meagan A Quinlan, Krista C Paffenroth, Fiona E Harrison, Cristina Fenollar-Ferrer, Rania M Katamish, Isabel Stillman, Sammanda Ramamoorthy, Randy D Blakel. Serotonin Transporter Ala276 Mouse: Novel Model to Assess the Neurochemical and Behavioral Impact of Thr276 Phosphorylation In Vivo. Neurochemical research. 2021-04-08. PMID:33830406. |
similarly, no genotype differences were evident in midbrain or hippocampal 5-ht levels, midbrain and hippocampal sert mrna or midbrain protein levels, nor in midbrain synaptosomal 5-ht uptake kinetics. |
2021-04-08 |
2023-08-13 |
mouse |
| Lucia Caffino, Francesca Mottarlini, Boyd Van Reijmersdal, Francesca Telese, Michel M M Verheij, Fabio Fumagalli, Judith R Homber. The role of the serotonin transporter in prefrontal cortex glutamatergic signaling following short- and long-access cocaine self-administration. Addiction biology. vol 26. issue 2. 2021-03-26. PMID:32187792. |
we previously demonstrated that serotonin transporter knockout (sert |
2021-03-26 |
2023-08-13 |
Not clear |
| Aman Kumar, Regan M Russell, Reed Pifer, Zelia Menezes-Garcia, Santiago Cuesta, Sanjeev Narayanan, John B MacMillan, Vanessa Sperandi. The Serotonin Neurotransmitter Modulates Virulence of Enteric Pathogens. Cell host & microbe. vol 28. issue 1. 2021-03-23. PMID:32521224. |
the neurotransmitter serotonin is primarily synthesized in the gastrointestinal (gi) tract, where it is secreted into the lumen and subsequently removed by the serotonin transporter, sert. |
2021-03-23 |
2023-08-13 |
Not clear |
| Aman Kumar, Regan M Russell, Reed Pifer, Zelia Menezes-Garcia, Santiago Cuesta, Sanjeev Narayanan, John B MacMillan, Vanessa Sperandi. The Serotonin Neurotransmitter Modulates Virulence of Enteric Pathogens. Cell host & microbe. vol 28. issue 1. 2021-03-23. PMID:32521224. |
increasing intestinal serotonin by genetically or pharmacologically inhibiting sert decreases lee expression and reduces c. rodentium loads. |
2021-03-23 |
2023-08-13 |
Not clear |
| Masaru Ihara, Han Zhang, Mariko O Ihara, Daisuke Kato, Hiroaki Tanak. Proposal for fluorescence-based in vitro assay using human and zebrafish monoamine transporters to detect biological activities of antidepressants in wastewater. The Science of the total environment. vol 770. 2021-03-18. PMID:33513512. |
we used app, a fluorescent substrate for monoamine transporters, to measure the activity of wastewater extracts at inhibiting app uptake through the human serotonin transporter (hsert), norepinephrine transporter (hnet), and dopamine transporter, and the zebrafish sert (zsert). |
2021-03-18 |
2023-08-13 |
human |
| Vadim Yuferov, Eduardo R Butelman, Matthew Randesi, Wim van den Brink, Peter Blanken, Jan M van Ree, Mary Jeanne Kree. Association of Serotonin Transporter (SERT) Polymorphisms with Opioid Dependence and Dimensional Aspects of Cocaine Use in a Caucasian Cohort of Opioid Users. Neuropsychiatric disease and treatment. vol 17. 2021-03-05. PMID:33658787. |
association of serotonin transporter (sert) polymorphisms with opioid dependence and dimensional aspects of cocaine use in a caucasian cohort of opioid users. |
2021-03-05 |
2023-08-13 |
human |
| Vadim Yuferov, Eduardo R Butelman, Matthew Randesi, Wim van den Brink, Peter Blanken, Jan M van Ree, Mary Jeanne Kree. Association of Serotonin Transporter (SERT) Polymorphisms with Opioid Dependence and Dimensional Aspects of Cocaine Use in a Caucasian Cohort of Opioid Users. Neuropsychiatric disease and treatment. vol 17. 2021-03-05. PMID:33658787. |
a functional tandem repeat polymorphism in the promoter of the serotonin transporter (sert) gene (slc6a4) has been studied for association to neuropsychiatric conditions, including substance use disorders. |
2021-03-05 |
2023-08-13 |
human |
| Verena Burtscher, Matej Hotka, Walter Sandtne. Detection of Ligand-binding to Membrane Proteins by Capacitance Measurements. Bio-protocol. vol 9. issue 1. 2021-03-03. PMID:30680295. |
herein, we describe the implementation of the same using recordings obtained from hek293 cells stably expressing the human serotonin transporter (sert), which were challenged with the inhibitor cocaine. |
2021-03-03 |
2023-08-13 |
human |
| Balasubramaniam Annamalai, Durairaj Ragu Varman, Rebecca E Horton, Lynette C Daws, Lankupalle D Jayanthi, Sammanda Ramamoorth. Histamine Receptors Regulate the Activity, Surface Expression, and Phosphorylation of Serotonin Transporters. ACS chemical neuroscience. vol 11. issue 3. 2021-03-03. PMID:31916747. |
serotonin transporter (sert) is mainly responsible for clearing the extracellular 5-ht. |
2021-03-03 |
2023-08-13 |
Not clear |
| Melodi A Bowman, Melissa Vitela, Kyra M Clarke, Wouter Koek, Lynette C Daw. Serotonin Transporter and Plasma Membrane Monoamine Transporter Are Necessary for the Antidepressant-Like Effects of Ketamine in Mice. International journal of molecular sciences. vol 21. issue 20. 2021-02-25. PMID:33066466. |
here we examined the role of the high-affinity, low-capacity serotonin transporter (sert), and the plasma membrane monoamine transporter (pmat), a low-affinity, high-capacity transporter for serotonin, as mechanisms contributing to ketamine's ability to increase extracellular serotonin and produce antidepressant-like effects. |
2021-02-25 |
2023-08-13 |
mouse |