| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Naheed Akhter, Mehir Un Nisa Iqbal, Aliya Maqsood, Safdar Ali Sheikh, Anwar Ali, Taseer Ahmed Kha. Association of BDNF and SERT gene polymorphisms with depression among Pakistani population. Pakistan journal of pharmaceutical sciences. vol 34. issue 1. 2021-07-12. PMID:34248009. |
brain-derived neurotrophic factor (bdnf) and serotonin transporter (sert) is implicated in the adverse life events which lead to depression. |
2021-07-12 |
2023-08-13 |
human |
| Navasona Krishnan, Xiaoying Chen, Diana Donnelly-Roberts, Eric G Mohler, David M Holtzman, Sujatha M Gopalakrishna. Small Molecule Phenotypic Screen Identifies Novel Regulators of LDLR Expression. ACS chemical biology. vol 15. issue 12. 2021-07-07. PMID:33270420. |
the screen identified novel targets such as polo like kinase 1 (plk1), activin receptor like kinase 5 (alk5), and serotonin transporter (sert). |
2021-07-07 |
2023-08-13 |
mouse |
| Jonna M Leyrer-Jackson, Jose A Piña, Joseph McCallum, M Foster Olive, Cassandra D Gipso. Direct administration of ifenprodil and citalopram into the nucleus accumbens inhibits cue-induced nicotine seeking and associated glutamatergic plasticity. Brain structure & function. vol 225. issue 7. 2021-07-06. PMID:32591928. |
ifenprodil, which inhibits nicotine reinstatement when administered systemically, antagonizes glun2b-containing nmda receptors, has affinity for serotonin receptors, and blocks serotonin transporters (sert). |
2021-07-06 |
2023-08-13 |
rat |
| Frederick S Barrett, Clifford I Workman, Haris I Sair, Alena V Savonenko, Michael A Kraut, Devin J Sodums, Jin J Joo, Najlla Nassery, Christopher M Marano, Cynthia A Munro, Jason Brandt, Yun Zhou, Dean F Wong, Gwenn S Smit. Association between serotonin denervation and resting-state functional connectivity in mild cognitive impairment. Human brain mapping. vol 38. issue 7. 2021-07-03. PMID:28379618. |
the current study investigated the relationship between serotonin transporter availability (sert; measured using positron emission tomography) and brain network functional connectivity (measured using resting-state functional mri) in 20 participants with mci and 21 healthy controls. |
2021-07-03 |
2023-08-13 |
human |
| Maximilian Gahr, Bernhard J Connemann, Rainer Muche, René Zeis. The Impact of Serotonin Transporter Binding Affinity on the Risk of Bleeding Related to Antidepressants. Journal of clinical psychopharmacology. vol 41. issue 4. 2021-06-29. PMID:34181363. |
there is some evidence that a substance's degree of serotonin reuptake inhibition in terms of its binding affinity to the serotonin transporter (sert) affects the magnitude of bleeding risk increase. |
2021-06-29 |
2023-08-13 |
Not clear |
| Shiv Shanker, Neeshu Saroj, Emilio J Cordova, Rosa A Jarillo-Luna, Pedro López-Sánchez, José A Terró. Chronic restraint stress induces serotonin transporter expression in the rat adrenal glands. Molecular and cellular endocrinology. vol 518. 2021-06-25. PMID:32659440. |
we analysed the impact of crs on serotonin transporter (sert) expression and distribution in rat adrenal glands. |
2021-06-25 |
2023-08-13 |
rat |
| Alexandr Pak, Alexander A Chubyki. Cortical Tuning is Impaired After Perceptual Experience in Primary Visual Cortex of Serotonin Transporter-Deficient Mice. Cerebral cortex communications. vol 1. issue 1. 2021-06-25. PMID:33134928. |
its signaling is tightly regulated by the serotonin transporter (sert), alterations of which were implicated in various neurological and psychiatric disorders. |
2021-06-25 |
2023-08-13 |
mouse |
| Jimmy Olusakin, Imane Moutkine, Sylvie Dumas, Evgeni Ponimaskin, Eleni Paizanis, Mariano Soiza-Reilly, Patricia Gaspa. Implication of 5-HT7 receptor in prefrontal circuit assembly and detrimental emotional effects of SSRIs during development. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 13. 2021-06-23. PMID:32688364. |
changes in serotonin homeostasis during critical periods produced by genetic or pharmacological inactivation of the serotonin transporter (sert, or slc6a4), have been involved in such developmental effects. |
2021-06-23 |
2023-08-13 |
mouse |
| Samantha E Stilley, Randy D Blakel. Rare Opportunities for Insights Into Serotonergic Contributions to Brain and Bowel Disorders: Studies of the SERT Ala56 Mouse. Frontiers in cellular neuroscience. vol 15. 2021-06-22. PMID:34149362. |
altered structure, expression, and regulation of the presynaptic serotonin (5-ht) transporter (sert) have been associated with multiple neurobehavioral disorders, including mood disorders, obsessive-compulsive disorder (ocd), and autism spectrum disorder (asd). |
2021-06-22 |
2023-08-13 |
mouse |
| Roberto De Gregorio, Xiaoning Chen, Emilie I Petit, Kostantin Dobrenis, Ji Ying Sz. Disruption of Transient SERT Expression in Thalamic Glutamatergic Neurons Alters Trajectory of Postnatal Interneuron Development in the Mouse Cortex. Cerebral cortex (New York, N.Y. : 1991). vol 30. issue 3. 2021-06-21. PMID:31504267. |
our previous work demonstrated that transient expression (e15-p10) of serotonin uptake transporter (sert) in thalamocortical projection neurons regulates barrel elaboration during cortical map establishment. |
2021-06-21 |
2023-08-13 |
mouse |
| Lucia Caffino, Michel M M Verheij, Karine Roversi, Giorgia Targa, Francesca Mottarlini, Piotr Popik, Agnieska Nikiforuk, Joanna Golebiowska, Fabio Fumagalli, Judith R Homber. Hypersensitivity to amphetamine's psychomotor and reinforcing effects in serotonin transporter knockout rats: Glutamate in the nucleus accumbens. British journal of pharmacology. vol 177. issue 19. 2021-06-21. PMID:32721055. |
previous research showed that inherited serotonin transporter (sert) down-regulation increases the motor response to cocaine, as well as moderate (as measured during daily 1-h self-administration sessions) and compulsive (as measured during daily 6-h self-administration sessions) intake of this psychostimulant. |
2021-06-21 |
2023-08-13 |
rat |
| Christopher Manzella, Megha Singhal, Max Ackerman, Waddah A Alrefai, Seema Saksena, Pradeep K Dudeja, Ravinder K Gil. Serotonin transporter untranslated regions influence mRNA abundance and protein expression. Gene reports. vol 18. 2021-06-21. PMID:34113740. |
the serotonin transporter (sert, slc6a4) is a na |
2021-06-21 |
2023-08-13 |
Not clear |
| A Kautzky, T Vanicek, C Philippe, G S Kranz, W Wadsak, M Mitterhauser, A Hartmann, A Hahn, M Hacker, D Rujescu, S Kasper, R Lanzenberge. Machine learning classification of ADHD and HC by multimodal serotonergic data. Translational psychiatry. vol 10. issue 1. 2021-06-18. PMID:32265436. |
sixteen patients with adhd and 22 hc were scanned by pet to measure serotonin transporter (sert') binding potential with [ |
2021-06-18 |
2023-08-13 |
Not clear |
| Mo Xian Chen, Shu Cheng, Lei Lei, Xiao Fan Zhang, Qiang Liu, Aijin Lin, Chloe U Wallis, Michael James Lukowicz, Pak C Sham, Qi Li, Li Juan A. The effects of maternal SSRI exposure on the serotonin system, prefrontal protein expression and behavioral development in male and female offspring rats. Neurochemistry international. vol 146. 2021-06-18. PMID:33836218. |
moreover, down-regulation of 5-ht and sert expression were identified in the pfc. |
2021-06-18 |
2023-08-13 |
rat |
| Satoshi Matsuyama, Ryosuke Arakawa, Yuko Asam. [Studies on Monoamine Transporter Occupancy of Antidepressants using PET: Focusing on SERT and NET]. Brain and nerve = Shinkei kenkyu no shinpo. vol 73. issue 6. 2021-06-16. PMID:34127569. |
for antidepressive effects to appear, serotonin transporter (sert) occupancy should rise to 80% or higher. |
2021-06-16 |
2023-08-13 |
Not clear |
| Danielle M Diniz, Francesca Calabrese, Paola Brivio, Marco A Riva, Joanes Grandjean, Judith R Homber. BDNF Overexpression in the Ventral Hippocampus Promotes Antidepressant- and Anxiolytic-Like Activity in Serotonin Transporter Knockout Rats. International journal of molecular sciences. vol 22. issue 9. 2021-06-15. PMID:34068707. |
the serotonin knockout rat (sert |
2021-06-15 |
2023-08-13 |
human |
| Xi Li, Qingqing Liu, Jiaoyan Yu, Ruitao Zhang, Ting Sun, Wei Jiang, Na Hu, Peng Yang, Li Luo, Jing Ren, Qinhui Wang, Yan Wang, Qi Yan. Costunolide ameliorates intestinal dysfunction and depressive behaviour in mice with stress-induced irritable bowel syndrome Food & function. vol 12. issue 9. 2021-06-07. PMID:33977961. |
molecular docking showed that cos could form hydrogen bonds with the serotonin transporter (sert) to affect the reuptake of 5-ht in the intercellular space. |
2021-06-07 |
2023-08-13 |
mouse |
| b' Vjekoslav Peitl, Mario \\xc5\\xa0tefanovi\\xc4\\x87, Ivona Orlovi\\xc4\\x87, Jelena Culej, Ana Renduli\\xc4\\x87, Krunoslav Mate\\xc5\\xa1i\\xc4\\x87, Dalibor Karlovi\\xc4\\x8. Long acting aripiprazole influences cognitive functions in recent onset schizophrenia. Psychopharmacology. vol 238. issue 6. 2021-06-01. PMID:33580813.' |
cognitive impairments have also been associated with catechol-o-methyltransferase (comt), methylenetetrahydrofolate reductase (mthfr), and serotonin transporter (sert) gene polymorphisms which were earlier implicated in the pathophysiology of schizophrenia. |
2021-06-01 |
2023-08-13 |
Not clear |
| Gilciane Ceolin, Giulia Pipolo Rodrigues Mano, Natália Schmitt Hames, Luciana da Conceição Antunes, Elisa Brietzke, Débora Kurrle Rieger, Júlia Dubois Moreir. Vitamin D, Depressive Symptoms, and Covid-19 Pandemic. Frontiers in neuroscience. vol 15. 2021-06-01. PMID:34054418. |
the signaling of 1,25-dihydroxyvitamin d3, the active form of vitamin d, through vitamin d receptor (vdr) induces the expression of the gene of tryptophan hydroxylase 2 (tph2), influences the expression of serotonin reuptake transporter (sert) as well as the levels of monoamine oxidase-a (mao-a), the enzyme responsible for serotonin catabolism. |
2021-06-01 |
2023-08-13 |
Not clear |
| Armin Frille, Michael Rullmann, Georg-Alexander Becker, Marianne Patt, Julia Luthardt, Solveig Tiepolt, Hubert Wirtz, Osama Sabri, Swen Hesse, Hans-Juergen Seyfart. Increased pulmonary serotonin transporter in patients with chronic obstructive pulmonary disease who developed pulmonary hypertension. European journal of nuclear medicine and molecular imaging. vol 48. issue 4. 2021-05-28. PMID:33009594. |
the serotonin transporter (sert) may be involved in the pathogenesis of ph in patients with chronic-obstructive pulmonary disease (copd). |
2021-05-28 |
2023-08-13 |
Not clear |