| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Maria J Reimann, Merete Fredholm, Signe E Cremer, Liselotte B Christiansen, Kathryn M Meurs, Jacob E Møller, Jens Häggström, Jens Lykkesfeldt, Lisbeth H Olse. Polymorphisms in the serotonin transporter gene and circulating concentrations of neurotransmitters in Cavalier King Charles Spaniels with myxomatous mitral valve disease. Journal of veterinary internal medicine. 2021-10-02. PMID:34599615. |
in maltese dogs, 3 single nucleotide polymorphisms (snps) in the 5-ht transporter (sert) gene are suggested to associate with mmvd. |
2021-10-02 |
2023-08-13 |
Not clear |
| Speranta Avram, Miruna Silvia Stan, Ana Maria Udrea, Cătălin Buiu, Anca Andreea Boboc, Maria Merne. 3D-ALMOND-QSAR Models to Predict the Antidepressant Effect of Some Natural Compounds. Pharmaceutics. vol 13. issue 9. 2021-10-01. PMID:34575524. |
their antidepressant and neuroleptic activities were predicted by 3d-almond-qsar models built by considering three important targets, namely serotonin transporter (sert), 5-hydroxytryptamine receptor 1a (5-ht1a), and dopamine d2 receptor. |
2021-10-01 |
2023-08-13 |
Not clear |
| Ruibiao Fu, Zhongpeng Li, Rui Zhou, Chaoyang Li, Shuai Shao, Jin L. The mechanism of intestinal flora dysregulation mediated by intestinal bacterial biofilm to induce constipation. Bioengineered. vol 12. issue 1. 2021-09-27. PMID:34517785. |
the results showed that recombinant serotonin transporter (sert) messenger ribonucleic acid (mrna) level of the constipation population fecal fluid gavage group and the relative expression level of sert mrna were 1.61 ± 0.08 and 1.49 ± 0.06, which were higher markedly than those of distilled water group ( |
2021-09-27 |
2023-08-13 |
mouse |
| Zebin Lin, Chenyang Liu, Enshan Fan, Yurong Zhang, Shuiqing Zheng, Yulan Ra. An efficient and label-free LC-MS/MS method for assessing drug's activity at dopamine and serotonin transporters using transporter-transfected HEK293T cells. Journal of psychopharmacology (Oxford, England). vol 35. issue 6. 2021-09-24. PMID:33888022. |
dopamine transporter (dat) and serotonin transporter (sert) are targets for many psychoactive substances. |
2021-09-24 |
2023-08-13 |
Not clear |
| Bryony N Thorne, Bart A Ellenbroek, Darren J Da. Evaluation of i-Motif Formation in the Serotonin Transporter-Linked Polymorphic Region. Chembiochem : a European journal of chemical biology. vol 22. issue 2. 2021-09-22. PMID:32840058. |
the serotonin transporter (sert) is a key regulator of synaptic serotonin (5-ht), and its inhibition is an important pharmacological target for treating mdd. |
2021-09-22 |
2023-08-13 |
Not clear |
| Mariko Nakamura, Akira Yoshimi, Akihiro Mouri, Tatsuya Tokura, Hiroyuki Kimura, Shinichi Kishi, Tomoya Miyauchi, Kunihiro Iwamoto, Mikiko Ito, Aiji Sato-Boku, Norio Ozaki, Toshitaka Nabeshima, Yukihiro Nod. Duloxetine attenuates pain in association with downregulation of platelet serotonin transporter in patients with burning mouth syndrome and atypical odontalgia. Human psychopharmacology. 2021-09-20. PMID:34541697. |
the aim of this study was evaluation of the association between severity of pain and expression of total or ubiquitinated serotonin transporter (sert) protein in patients with burning mouth syndrome and atypical odontalgia (bms/ao), who were treated by duloxetine. |
2021-09-20 |
2023-08-13 |
Not clear |
| Yung-Chi Hsu, Kuo-Hsing Ma, Shu-Lin Guo, Bo-Feng Lin, Chien-Sung Tsai, Chun-Chang Ye. The Occurrence of Pain-Induced Depression Is Different between Rat Models of Inflammatory and Neuropathic Pain. Journal of clinical medicine. vol 10. issue 17. 2021-09-14. PMID:34501464. |
this frontward study investigated the differences in pain behavior, depression-like behavior, and serotonin transporter (sert) distribution in the brain between rats subjected to spared nerve injury (sni)-induced neuropathic pain or complete freund's adjuvant (cfa)-induced inflammatory pain. |
2021-09-14 |
2023-08-13 |
rat |
| Serika Motoike, Kei Taguchi, Kana Harada, Masaya Asano, Izumi Hide, Shigeru Tanaka, Masahiro Irifune, Norio Saka. Syntaxin 3 interacts with serotonin transporter and regulates its function. Journal of pharmacological sciences. vol 145. issue 4. 2021-09-10. PMID:33712280. |
herein, we investigated the functional association of the serotonin transporter (sert) with syntaxin-3 (stx3). |
2021-09-10 |
2023-08-13 |
Not clear |
| Serika Motoike, Kei Taguchi, Kana Harada, Masaya Asano, Izumi Hide, Shigeru Tanaka, Masahiro Irifune, Norio Saka. Syntaxin 3 interacts with serotonin transporter and regulates its function. Journal of pharmacological sciences. vol 145. issue 4. 2021-09-10. PMID:33712280. |
stx3 knockdown marginally but significantly decreased the serotonin uptake activity of caco-2 cells, suggesting that stx3 positively regulates sert function in caco-2 cells, as opposed to sert regulation by stx3 in overexpressing cells. |
2021-09-10 |
2023-08-13 |
Not clear |
| Foke L van de Blaak, Glenn J H Dumon. Serotonin transporter availability, neurocognitive function and their correlation in abstinent 3,4-methylenedioxymethamphetamine users. Human psychopharmacology. 2021-09-10. PMID:34506649. |
multiple neuroimaging studies have shown that ecstasy use leads to lower serotonin transporter (sert) availability in multiple brain regions. |
2021-09-10 |
2023-08-13 |
Not clear |
| Marvin V Dilworth, Heather E Findlay, Paula J Boot. Detergent-free purification and reconstitution of functional human serotonin transporter (SERT) using diisobutylene maleic acid (DIBMA) copolymer. Biochimica et biophysica acta. Biomembranes. vol 1863. issue 7. 2021-09-08. PMID:33744253. |
detergent-free purification and reconstitution of functional human serotonin transporter (sert) using diisobutylene maleic acid (dibma) copolymer. |
2021-09-08 |
2023-08-13 |
human |
| Karolina E Kolaczynska, Jan Thomann, Marius C Hoener, Matthias E Liecht. The Pharmacological Profile of Second Generation Pyrovalerone Cathinones and Related Cathinone Derivative. International journal of molecular sciences. vol 22. issue 15. 2021-09-08. PMID:34361040. |
we assessed several pyrovalerone and related cathinone derivatives at the human norepinephrine (net), dopamine (dat), and serotonin (sert) uptake transporters using hek293 cells overexpressing each respective transporter. |
2021-09-08 |
2023-08-13 |
human |
| Takahiro Ito, Yuka Hiramatsu, Akihiro Mouri, Takuya Yoshigai, Ayaki Takahashi, Akira Yoshimi, Takayoshi Mamiya, Norio Ozaki, Yukihiro Nod. Involvement of PKCβI-SERT activity in stress vulnerability of mice exposed to twice-swim stress. Neuroscience research. vol 171. 2021-09-06. PMID:33460682. |
stress vulnerability and pathogenic mechanisms in stress-related disorders are strongly associated with the functions of serotonin transporter (sert). |
2021-09-06 |
2023-08-13 |
mouse |
| Takahiro Ito, Yuka Hiramatsu, Akihiro Mouri, Takuya Yoshigai, Ayaki Takahashi, Akira Yoshimi, Takayoshi Mamiya, Norio Ozaki, Yukihiro Nod. Involvement of PKCβI-SERT activity in stress vulnerability of mice exposed to twice-swim stress. Neuroscience research. vol 171. 2021-09-06. PMID:33460682. |
sert phosphorylation induces a reduction of the serotonin (5-ht, 5-hydroxytryptamine) transport properties, its phosphorylation regulated by protein kinase c (pkc). |
2021-09-06 |
2023-08-13 |
mouse |
| Takahiro Ito, Yuka Hiramatsu, Akihiro Mouri, Takuya Yoshigai, Ayaki Takahashi, Akira Yoshimi, Takayoshi Mamiya, Norio Ozaki, Yukihiro Nod. Involvement of PKCβI-SERT activity in stress vulnerability of mice exposed to twice-swim stress. Neuroscience research. vol 171. 2021-09-06. PMID:33460682. |
phosphorylated pkcβi or sert and 5-ht levels were decreased in the prefrontal cortex of twice-stressed mice. |
2021-09-06 |
2023-08-13 |
mouse |
| Takahiro Ito, Yuka Hiramatsu, Akihiro Mouri, Takuya Yoshigai, Ayaki Takahashi, Akira Yoshimi, Takayoshi Mamiya, Norio Ozaki, Yukihiro Nod. Involvement of PKCβI-SERT activity in stress vulnerability of mice exposed to twice-swim stress. Neuroscience research. vol 171. 2021-09-06. PMID:33460682. |
our findings demonstrate that mice exposed to twice-swim stress developed stress vulnerability, which may be involved in the regulation of sert phosphorylation and 5-ht levels accompanying pkcβi activity. |
2021-09-06 |
2023-08-13 |
mouse |
| Anick Bérard, Michael Levin, Thomas Sadler, David Heal. Selective Serotonin Reuptake Inhibitor Use During Pregnancy and Major Malformations: The Importance of Serotonin for Embryonic Development and the Effect of Serotonin Inhibition on the Occurrence of Malformations. Bioelectricity. vol 1. issue 1. 2021-09-03. PMID:34471805. |
one of the key mediators of bioelectric control mechanisms is serotonin, and its transporter sert, which is targeted by a broad class of blocker drugs (selective serotonin reuptake inhibitors [ssris]). |
2021-09-03 |
2023-08-13 |
human |
| Maria Willadsen, Metin Uengoer, Rainer K W Schwarting, Judith R Homberg, Markus Wöh. Reduced emission of alarm 22-kHz ultrasonic vocalizations during fear conditioning in rats lacking the serotonin transporter. Progress in neuro-psychopharmacology & biological psychiatry. vol 108. 2021-09-02. PMID:32800867. |
a key component of the system is the 5-ht transporter (5-htt, also known as sert), regulating 5-ht availability in the synaptic cleft. |
2021-09-02 |
2023-08-13 |
rat |
| Takahiro Ito, Yuka Hiramatsu, Mizuki Uchida, Akira Yoshimi, Takayoshi Mamiya, Akihiro Mouri, Norio Ozaki, Yukihiro Nod. Involvement of protein kinase C beta1-serotonin transporter system dysfunction in emotional behaviors in stressed mice. Neurochemistry international. vol 140. 2021-09-02. PMID:32818536. |
these inhibitors directly bind to the serotonin transporter (sert). |
2021-09-02 |
2023-08-13 |
mouse |
| Per Plenge, Dongxue Yang, Kristine Salomon, Louise Laursen, Iris E Kalenderoglou, Amy H Newman, Eric Gouaux, Jonathan A Coleman, Claus J Lolan. The antidepressant drug vilazodone is an allosteric inhibitor of the serotonin transporter. Nature communications. vol 12. issue 1. 2021-08-31. PMID:34417466. |
all characterized ssris are competitive inhibitors of the serotonin transporter (sert). |
2021-08-31 |
2023-08-13 |
Not clear |