| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Durairaj Ragu Varman, Lankupalle D Jayanthi, Sammanda Ramamoorth. Kappa Opioid Receptor Mediated Differential Regulation of Serotonin and Dopamine Transporters in Mood and Substance Use Disorder. Handbook of experimental pharmacology. vol 271. 2021-11-26. PMID:34136961. |
also, we discuss the recent findings on kor-mediated differential regulation of serotonin and dopamine transporters (sert and dat). |
2021-11-26 |
2023-08-13 |
Not clear |
| Ahmad Qasem, Abed Elrahman Naser, Saleh A Nase. Enteropathogenic infections modulate intestinal serotonin transporter (SERT) function by activating Toll-like receptor 2 (TLR-2) in Crohn's disease. Scientific reports. vol 11. issue 1. 2021-11-23. PMID:34799637. |
enteropathogenic infections modulate intestinal serotonin transporter (sert) function by activating toll-like receptor 2 (tlr-2) in crohn's disease. |
2021-11-23 |
2023-08-13 |
human |
| Ahmad Qasem, Abed Elrahman Naser, Saleh A Nase. Enteropathogenic infections modulate intestinal serotonin transporter (SERT) function by activating Toll-like receptor 2 (TLR-2) in Crohn's disease. Scientific reports. vol 11. issue 1. 2021-11-23. PMID:34799637. |
availability of the intestinal 5-ht is dependent on serotonin transporter (sert), which uptakes 5-ht and facilitates its degradation. |
2021-11-23 |
2023-08-13 |
human |
| S L Field, M G Marrero, B Dado-Senn, A L Skibiel, P M Ramos, T L Scheffler, J Laport. Peripheral serotonin regulates glucose and insulin metabolism in Holstein dairy calves. Domestic animal endocrinology. vol 74. 2021-11-19. PMID:32739765. |
the liver and pancreas of preweaned calves express serotonin factors (ie, tph1, sert, and cell surface receptors), indicating their ability to synthesize, uptake, and respond to serotonin. |
2021-11-19 |
2023-08-13 |
Not clear |
| Rody Kingston, Dwarkesh Amin, Sneha Misra, Jeffrey M Gross, Takaaki Kuwajim. Serotonin transporter-mediated molecular axis regulates regional retinal ganglion cell vulnerability and axon regeneration after nerve injury. PLoS genetics. vol 17. issue 11. 2021-11-19. PMID:34735454. |
mechanistically, the serotonin transporter (sert) is upregulated on vt axons after injury. |
2021-11-19 |
2023-08-13 |
mouse |
| Jessica Romero-Reyes, Edgar Ricardo Vázquez-Martínez, Daniel Bahena-Alvarez, Jessica López-Jiménez, Anayansi Molina-Hernández, Ignacio Camacho-Arroyo, Néstor Fabián Día. Differential localization of serotoninergic system elements in human amniotic epithelial cells†. Biology of reproduction. vol 105. issue 2. 2021-11-18. PMID:34057176. |
we found the expression of tryptophan hydroxylase type 1 (tph1), type 2 (tph2), serotonin transporter (sert), monoamine oxidase-a (maoa), as well as htr1d and htr7 receptors at mrna level in amnion tissue as well in haec. |
2021-11-18 |
2023-08-13 |
human |
| Takashi Sonobe, Tsuyoshi Akiyama, James T Pearso. Carrier-mediated serotonin efflux induced by pharmacological anoxia in the rat heart in vivo. Clinical and experimental pharmacology & physiology. vol 48. issue 12. 2021-11-18. PMID:34411314. |
the results indicate that reverse transport of 5-ht via sert, which is caused by an impaired ion gradient, contributes to the rise in interstitial level of 5-ht during ischaemia suggesting carrier-mediated 5-ht efflux occurs in the heart in vivo. |
2021-11-18 |
2023-08-13 |
rat |
| Jana Haase, Aimée K C Jones, Conor J Mc Veigh, Eric Brown, Gerard Clarke, Gudrun Ahnert-Hilge. Sex and brain region-specific regulation of serotonin transporter activity in synaptosomes in guanine nucleotide-binding protein G(q) alpha knockout mice. Journal of neurochemistry. vol 159. issue 1. 2021-11-17. PMID:34309872. |
the regulation of the serotonin transporter (sert) by guanine nucleotide-binding protein alpha (gα) q was investigated using gαq knockout mice. |
2021-11-17 |
2023-08-13 |
mouse |
| Jana Haase, Aimée K C Jones, Conor J Mc Veigh, Eric Brown, Gerard Clarke, Gudrun Ahnert-Hilge. Sex and brain region-specific regulation of serotonin transporter activity in synaptosomes in guanine nucleotide-binding protein G(q) alpha knockout mice. Journal of neurochemistry. vol 159. issue 1. 2021-11-17. PMID:34309872. |
likely due to differential sert regulation as well as sex differences in the expression of tryptophan hydroxylase 2, gαq knockout mice also displayed sex- and genotype-dependent alterations in total 5ht tissue levels as determined by high-performance liquid chromatography. |
2021-11-17 |
2023-08-13 |
mouse |
| Jana Haase, Aimée K C Jones, Conor J Mc Veigh, Eric Brown, Gerard Clarke, Gudrun Ahnert-Hilge. Sex and brain region-specific regulation of serotonin transporter activity in synaptosomes in guanine nucleotide-binding protein G(q) alpha knockout mice. Journal of neurochemistry. vol 159. issue 1. 2021-11-17. PMID:34309872. |
bim-46187, which promotes the nucleotide-free form of gα proteins, substantially inhibited 5ht uptake, prompting us to hypothesise that gαq interacts with sert similarly as with g-protein-coupled receptors and inhibits sert activity by modulating transport-associated conformational changes. |
2021-11-17 |
2023-08-13 |
mouse |
| Jana Haase, Aimée K C Jones, Conor J Mc Veigh, Eric Brown, Gerard Clarke, Gudrun Ahnert-Hilge. Sex and brain region-specific regulation of serotonin transporter activity in synaptosomes in guanine nucleotide-binding protein G(q) alpha knockout mice. Journal of neurochemistry. vol 159. issue 1. 2021-11-17. PMID:34309872. |
taken together, our findings reveal a novel mechanism of sert regulation and impact our understanding of sex differences in diseases associated with dysregulation of serotonin transmission, such as depression and anxiety. |
2021-11-17 |
2023-08-13 |
mouse |
| Charlotte P Magee, BaoMinh D Le, Yasmeen H Siripathane, Diana G Wilkins, Glen R Hanson, Annette E Fleckenstei. Methcathinone decreases dopamine transporter function: Role of protein kinase C. Journal of neurochemistry. vol 159. issue 1. 2021-11-17. PMID:34320222. |
thus, effects of mcat on 1) striatal dopamine (da) transporter (dat); and 2) striatal and hippocampal serotonin transporter (sert) function, as determined in tissues from adult male rats, were assessed. |
2021-11-17 |
2023-08-13 |
rat |
| M Engevik, W Ruan, C Visuthranukul, Z Shi, K A Engevik, A C Engevik, R Fultz, D A Schady, J K Spinler, J Versalovi. Beneficial microbes. vol 12. issue 6. 2021-11-16. PMID:34550056. |
the serotonin transporter (sert) readily takes up serotonin (5-ht), thereby regulating the availability of 5-ht within the intestine. |
2021-11-16 |
2023-08-13 |
mouse |
| M Engevik, W Ruan, C Visuthranukul, Z Shi, K A Engevik, A C Engevik, R Fultz, D A Schady, J K Spinler, J Versalovi. Beneficial microbes. vol 12. issue 6. 2021-11-16. PMID:34550056. |
in the absence of sert, 5-ht remains in the interstitial space and has the potential to aberrantly activate the many 5-ht receptors distributed on the epithelium, immune cells and enteric neurons. |
2021-11-16 |
2023-08-13 |
mouse |
| Daniel Chaji, Varun S Venkatesh, Tomoaki Shirao, Darren J Day, Bart A Ellenbroe. Genetic Knockout of the Serotonin Reuptake Transporter Results in the Reduction of Dendritic Spines in In vitro Rat Cortical Neuronal Culture. Journal of molecular neuroscience : MN. vol 71. issue 11. 2021-11-12. PMID:33403594. |
changes in the expression of the serotonin transporter (sert) through polymorphisms in the regulatory regions of the sert gene have been associated, but not yet been conclusively linked to, neuropsychiatric disorders. |
2021-11-12 |
2023-08-13 |
rat |
| Bert Thys, Andrea S Grunst, Nicky Staes, Rianne Pinxten, Marcel Eens, Melissa L Gruns. The serotonin transporter gene and female personality variation in a free-living passerine. Scientific reports. vol 11. issue 1. 2021-11-12. PMID:33883685. |
here, using a population of free-living great tits (parus major), we assessed the association between single nucleotide polymorphisms (snps) in the serotonin transporter gene (sert) and two repeatable behavioural traits, i.e. |
2021-11-12 |
2023-08-13 |
Not clear |
| Yoko Hagino, Frank Scott Hall, George R Uhl, Ichiro Sora, Kazutaka Iked. Dual actions of 5-MeO-DIPT at the serotonin transporter and serotonin 5-HT Neuropsychopharmacology reports. vol 41. issue 1. 2021-11-09. PMID:33547882. |
the present study examined whether the effects of 5-meo-dipt involve the serotonin transporter (sert) and serotonin 5-hydroxytryptamine-1a (5-ht |
2021-11-09 |
2023-08-13 |
Not clear |
| Katy A van Galen, Jan Booij, Anouk Schrantee, Sofie M Adriaanse, Unga A Unmehopa, Eric Fliers, Gary J Schwartz, Ralph J DiLeone, Kasper W Ter Horst, Susanne E la Fleur, Mireille J Serli. The response to prolonged fasting in hypothalamic serotonin transporter availability is blunted in obesity. Metabolism: clinical and experimental. vol 123. 2021-11-09. PMID:34331964. |
we therefore aimed to evaluate the effects of fasting on hypothalamic/thalamic serotonin transporter (sert) and striatal dopamine transporter (dat) availability in lean subjects and subjects with obesity. |
2021-11-09 |
2023-08-13 |
human |
| Allison N White, Joshua D Gross, Shane W Kaski, Kristen R Trexler, Kim A Wix, William C Wetsel, Steven G Kinsey, David P Siderovski, Vincent Setol. Genetic deletion of Journal of psychopharmacology (Oxford, England). vol 34. issue 12. 2021-11-04. PMID:32842837. |
this effect on dat prompted us to investigate whether the serotonin transporter (sert) exhibits similar alterations upon rgs12 loss in c57bl/6j mice. |
2021-11-04 |
2023-08-13 |
mouse |
| Chen Li, Fantao Meng, Jacob C Garza, Jing Liu, Yun Lei, Sergei A Kirov, Ming Guo, Xin-Yun L. Modulation of depression-related behaviors by adiponectin AdipoR1 receptors in 5-HT neurons. Molecular psychiatry. vol 26. issue 8. 2021-11-02. PMID:31980728. |
in addition, serotonin transporter (sert) expression was upregulated in both drn projection fields of male mice but only in the mpfc of female mice. |
2021-11-02 |
2023-08-13 |
mouse |