| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christine M Bubac, Catherine I Cullingham, Janay A Fox, W Don Bowen, Cornelia E den Heyer, David W Coltma. Genetic association with boldness and maternal performance in a free-ranging population of grey seals (Halichoerus grypus). Heredity. vol 127. issue 1. 2021-11-01. PMID:33927365. |
we isolated and re-sequenced five genes: dopamine receptor d4 (drd4), serotonin transporter (sert), oxytocin receptor (oxtr), and melanocortin receptors 1 (mc1r) and 5 (mc5r). |
2021-11-01 |
2023-08-13 |
Not clear |
| Jeong-Hee Kim, Young-Don Son, Hang-Keun Kim, Jong-Hoon Ki. Association Between Lack of Insight and Prefrontal Serotonin Transporter Availability in Antipsychotic-Free Patients with Schizophrenia: A High-Resolution PET Study with [ Neuropsychiatric disease and treatment. vol 17. 2021-10-30. PMID:34707358. |
in this study, we examined the relationship between serotonin transporter (sert) availability in regions of the prefrontal cortex (dorsolateral, ventrolateral, ventromedial, and orbitofrontal cortices) and insight deficits in antipsychotic-free patients with schizophrenia using high-resolution positron emission tomography (pet) with [ |
2021-10-30 |
2023-08-13 |
Not clear |
| Tudor M Ionescu, Mario Amend, Rakibul Hafiz, Bharat B Biswal, Andreas Maurer, Bernd J Pichler, Hans F Wehrl, Kristina Herfer. Striatal and prefrontal D2R and SERT distributions contrastingly correlate with default-mode connectivity. NeuroImage. vol 243. 2021-10-29. PMID:34428573. |
the aim of this study was elucidating interactions between dopamine d2 receptors (d2r) and serotonin transporter (sert) availabilities in the striatum (cpu) and medial prefrontal cortex (mpfc), two of the main dopaminergic and serotonergic projection areas, and the default-mode network. |
2021-10-29 |
2023-08-13 |
rat |
| Olof R Hjorth, Andreas Frick, Malin Gingnell, Johanna M Hoppe, Vanda Faria, Sara Hultberg, Iman Alaie, Kristoffer N T Månsson, Kurt Wahlstedt, My Jonasson, Mark Lubberink, Gunnar Antoni, Mats Fredrikson, Tomas Furmar. Expression and co-expression of serotonin and dopamine transporters in social anxiety disorder: a multitracer positron emission tomography study. Molecular psychiatry. vol 26. issue 8. 2021-10-28. PMID:31822819. |
the aim of this multitracer pet study was to evaluate the regional expression and co-expression of the transporter proteins for serotonin (sert) and dopamine (dat) in patients with social anxiety disorder (sad). |
2021-10-28 |
2023-08-13 |
Not clear |
| Lu Xiao, Junyan Yan, Ting Yang, Jiang Zhu, Tingyu Li, Hong Wei, Jie Che. Fecal Microbiome Transplantation from Children with Autism Spectrum Disorder Modulates Tryptophan and Serotonergic Synapse Metabolism and Induces Altered Behaviors in Germ-Free Mice. mSystems. vol 6. issue 2. 2021-10-28. PMID:33824200. |
western blotting detected the protein expression levels of tryptophan hydroxylase 1 (tph1), serotonin transporter (sert), and serotonin 1a receptor (5-ht1ar) in the colon and tph2, sert, and 5-ht1ar in the prefrontal cortex of mice. |
2021-10-28 |
2023-08-13 |
mouse |
| Anna Marie Buchanan, Brenna Parke, Parastoo Hashem. Experimental Methods for Investigating Uptake 2 Processes In Vivo. Handbook of experimental pharmacology. vol 266. 2021-10-28. PMID:34196807. |
uptake 1 describes uptake of the monoamine via its designated transporter (sert for serotonin, net for norepinephrine, and dat for dopamine), whereas uptake 2 details multiple transporter types on neurons and glia taking up different types of modulators, not necessarily specific to the monoamine. |
2021-10-28 |
2023-08-13 |
human |
| Lynette C Daw. Organic Cation Transporters in Psychiatric Disorders. Handbook of experimental pharmacology. vol 266. 2021-10-28. PMID:34282486. |
ssris act by blocking the serotonin transporter (sert), the high-affinity, low-capacity, uptake-1 transporter for serotonin. |
2021-10-28 |
2023-08-13 |
Not clear |
| Anders Sørensen, Henricus G Ruhé, Klaus Munkhol. The relationship between dose and serotonin transporter occupancy of antidepressants-a systematic review. Molecular psychiatry. 2021-10-26. PMID:34548628. |
brain imaging techniques enable the visualization of serotonin transporter (sert) occupancy as a measure of the proportion of sert blocked by an antidepressant at a given dose. |
2021-10-26 |
2023-08-13 |
human |
| Wenlu Pan, Jing Pan, Yan Zhao, Hongzheng Zhang, Jie Tan. Serotonin Transporter Defect Disturbs Structure and Function of the Auditory Cortex in Mice. Frontiers in neuroscience. vol 15. 2021-10-26. PMID:34690685. |
serotonin transporter (sert) modulates the level of 5-ht and significantly affects the activity of serotonergic neurons in the central nervous system. |
2021-10-26 |
2023-08-13 |
mouse |
| Yu Zhang, Hua Zhang, Wen Zhang, Yingjuan Zhang, Wei Wang, Lihong Ni. LncRNA XIST modulates 5-hydroxytrytophan-induced visceral hypersensitivity by epigenetic silencing of the SERT gene in mice with diarrhea-predominant IBS. Cellular signalling. vol 73. 2021-10-25. PMID:32446903. |
restoration of lncrna xist resulted in increased awr score, counts of peristaltic wave, abdominal wall contraction and defecation particles along with stimulated 5-ht expression and sert methylation level, while downregulation of lncrna xist reversed these effects. |
2021-10-25 |
2023-08-13 |
mouse |
| Héctor Miguel Mancha-Gutiérrez, Erika Estrada-Camarena, Lilian Mayagoitia-Novales, Elena López-Pacheco, Carolina López-Rubalcav. Chronic Social Defeat During Adolescence Induces Short- and Long-Term Behavioral and Neuroendocrine Effects in Male Swiss-Webster Mice. Frontiers in behavioral neuroscience. vol 15. 2021-10-22. PMID:34658806. |
finally, corticosterone and testosterone content was measured before, during, and after csd exposure, and serotonin transporter (sert) autoradiography was studied after csd in adolescent and adult mice. |
2021-10-22 |
2023-08-13 |
mouse |
| Preeti Singh, Terry W Fletcher, Yicong Li, Nancy J Rusch, Fusun Kili. Serotonin uptake rates in platelets from angiotensin II-induced hypertensive mice. Health. vol 5. issue 4A. 2021-10-21. PMID:24163726. |
one of the abnormalities presented to the platelets during hypertension is an elevated plasma concentration of serotonin (5-ht) caused by reduced 5-ht uptake secondary to loss of the 5-ht transporter (sert) on the platelet plasma membrane. |
2021-10-21 |
2023-08-12 |
mouse |
| Shreyas Bhat, Marco Niello, Klaus Schicker, Christian Pifl, Harald H Sitte, Michael Freissmuth, Walter Sandtne. Handling of intracellular K eLife. vol 10. 2021-10-19. PMID:34061030. |
handling of intracellular k the concentrative power of the transporters for dopamine (dat), norepinephrine (net), and serotonin (sert) is thought to be fueled by the transmembrane na |
2021-10-19 |
2023-08-13 |
Not clear |
| Gerald Sosla. Cardiovascular serotonergic system: Evolution, receptors, transporter, and function. Journal of experimental zoology. Part A, Ecological and integrative physiology. 2021-10-18. PMID:34662506. |
the serotonergic system, serotonin (5ht), serotonin transporter (sert), and serotonin receptors (5ht-x), is an evolutionarily ancient system that has clear physiological advantages to all life forms from bacteria to humans. |
2021-10-18 |
2023-08-13 |
Not clear |
| Danielle J Houwing, Kirsten Schuttel, Eline L Struik, Chantal Arling, Anouschka S Ramsteijn, I Heinla, Jocelien D A Olivie. Perinatal fluoxetine treatment and dams' early life stress history alter affective behavior in rat offspring depending on serotonin transporter genotype and sex. Behavioural brain research. vol 392. 2021-10-13. PMID:32339551. |
as reduced serotonin transporter (sert) availability has been associated with altered behavioral outcome, both offspring with normal (sert |
2021-10-13 |
2023-08-13 |
rat |
| Carolina Costa, Miguel Semedo, Sandrine P Machado, Virginia Cunha, Marta Ferreira, Ralph Urbatzk. Transcriptional analyses reveal different mechanism of toxicity for a chronic exposure to fluoxetine and venlafaxine on the brain of the marine fish Dicentrarchrus labrax. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. vol 250. 2021-10-08. PMID:34454087. |
both psychopharmaceuticals affected differentially the neurotransmitter mrna expression analyzed by rt-qpcr (serotonin receptors: 5-ht3a, 5-ht3b; dopamine receptors: d2, d3; neurotransmitter transporter: sert, vmat; degrading enzyme: mao). |
2021-10-08 |
2023-08-13 |
Not clear |
| Sonali N Reisinger, Eryan Kong, Deeba Khan, Stefan Schulz, Marianne Ronovsky, Stefanie Berger, Orsolya Horvath, Maureen Cabatic, Angelika Berger, Daniela D Polla. Maternal immune activation epigenetically regulates hippocampal serotonin transporter levels. Neurobiology of stress. vol 4. 2021-10-06. PMID:27981188. |
morevoer, specific changes at the promoter and in the expression of the serotonin transporter (sert), critically involved in the etiology of mdd and pharmacological antidepressant treatment were detected. |
2021-10-06 |
2023-08-13 |
mouse |
| M A Schiele, P Zwanzger, K Schwarte, V Arolt, B T Baune, K Domschk. Serotonin Transporter Gene Promoter Hypomethylation as a Predictor of Antidepressant Treatment Response in Major Depression: A Replication Study. The international journal of neuropsychopharmacology. vol 24. issue 3. 2021-10-06. PMID:33125470. |
the serotonin transporter gene (slc6a4; 5-htt; sert) is considered a prime candidate in pharmacogenetic research in major depressive disorder (mdd). |
2021-10-06 |
2023-08-13 |
Not clear |
| R Seiger, G Gryglewski, M Klöbl, A Kautzky, G M Godbersen, L Rischka, T Vanicek, M Hienert, J Unterholzner, L R Silberbauer, P Michenthaler, P Handschuh, A Hahn, S Kasper, R Lanzenberge. The Influence of Acute SSRI Administration on White Matter Microstructure in Patients Suffering From Major Depressive Disorder and Healthy Controls. The international journal of neuropsychopharmacology. vol 24. issue 7. 2021-10-06. PMID:33667309. |
these antidepressants exert their effects by blocking the serotonin transporter (sert), leading to increased levels of serotonin in the synaptic cleft and subsequently to an attenuation of depressive symptoms and elevation in mood. |
2021-10-06 |
2023-08-13 |
Not clear |
| Amber N Edinoff, Juliana M Fort, Joshua J Woo, Christopher D Causey, Caroline R Burroughs, Elyse M Cornett, Adam M Kaye, Alan D Kay. Selective Serotonin Reuptake Inhibitors and Clozapine: Clinically Relevant Interactions and Considerations. Neurology international. vol 13. issue 3. 2021-10-02. PMID:34564289. |
the preferential targeting of serotonin receptor (sert) by selective serotonin reuptake inhibitors (ssris) has offered an opportunity to reduce the range of these side effects and improve patient adherence to pharmacotherapy. |
2021-10-02 |
2023-08-13 |
Not clear |