| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C L Bethea, C Gundlah, S J Mirke. Ovarian steroid action in the serotonin neural system of macaques. Novartis Foundation symposium. vol 230. 2001-01-25. PMID:10965505. |
serotonin reuptake transporter (sert) mrna decreased significantly with oestrogen treatment and addition of progesterone had no further effect. |
2001-01-25 |
2023-08-12 |
monkey |
| A Najib, P Pelliccioni, C Gil, J Aguiler. Serotonin transporter phosphorylation modulated by tetanus toxin. FEBS letters. vol 486. issue 2. 2001-01-25. PMID:11113454. |
activation of pkc by both tetx and tpa results in a loss of transport capacity and serotonin transporter (sert) phosphorylation, which are abolished by coapplication of the specific pkc inhibitor bisindolylmaleimide-1. |
2001-01-25 |
2023-08-12 |
rat |
| Y Zhang, R B Rothman, C M Dersch, B R de Costa, A E Jacobson, K C Ric. Synthesis and transporter binding properties of bridged piperazine analogues of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR 12909). Journal of medicinal chemistry. vol 43. issue 25. 2001-01-18. PMID:11123994. |
1]bicyclooctane analogues of 3, showed high affinity for the dat (ic(50) = 8.0 and 8.2 nm, respectively), and 7 had high selectivity at the dat relative to the serotonin transporter (sert) (88- and 93-fold for binding and reuptake, respectively). |
2001-01-18 |
2023-08-12 |
Not clear |
| G Carrasco, M A Cruz, A Dominguez, V Gallardo, P Miguel, C Gonzále. The expression and activity of monoamine oxidase A, but not of the serotonin transporter, is decreased in human placenta from pre-eclamptic pregnancies. Life sciences. vol 67. issue 24. 2001-01-18. PMID:11133008. |
we have attempted to elucidate the possible participation of 5-ht as an aetiological factor in pre-eclampsia, by estimating the activity and expression of the 5-ht transporter (sert) and monoamine oxidase a (mao-a) in human placenta from full term normal (ng) and severe pre-eclamptic (pes) pregnancies. |
2001-01-18 |
2023-08-12 |
human |
| L H Miner, S Schroeter, R D Blakely, S R Sesac. Ultrastructural localization of the serotonin transporter in superficial and deep layers of the rat prelimbic prefrontal cortex and its spatial relationship to dopamine terminals. The Journal of comparative neurology. vol 427. issue 2. 2001-01-04. PMID:11054690. |
dopamine levels within the prefrontal cortex (pfc) can be manipulated by selective inhibitors of the serotonin transporter (sert). |
2001-01-04 |
2023-08-12 |
rat |
| S R Choi, C Hou, S Oya, M Mu, M P Kung, M Siciliano, P D Acton, H F Kun. Selective in vitro and in vivo binding of [(125)I]ADAM to serotonin transporters in rat brain. Synapse (New York, N.Y.). vol 38. issue 4. 2000-12-14. PMID:11044887. |
an improved iodinated tracer, adam (2-((2-((dimethylamino)methyl)- phenyl)thio)-5-iodophenylamine) for imaging serotonin transporters (sert) with single photon emission computerized tomography (spect), was prepared and characterized. |
2000-12-14 |
2023-08-12 |
rat |
| T Sander, W Berlin, A Ostapowicz, J Samochowiec, N Gscheidel, M R Hoeh. Variation of the genes encoding the human glutamate EAAT2, serotonin and dopamine transporters and Susceptibility to idiopathic generalized epilepsy. Epilepsy research. vol 41. issue 1. 2000-11-20. PMID:10924870. |
the genotypes of 133 german ige subjects and 223 ethnically matched controls were assessed for dna polymorphisms of genes encoding the glutamate (eaat2), the serotonin (sert), and dopamine (dat) transporters. |
2000-11-20 |
2023-08-12 |
human |
| H M Haughey, A E Fleckenstein, R R Metzger, G R Hanso. The effects of methamphetamine on serotonin transporter activity: role of dopamine and hyperthermia. Journal of neurochemistry. vol 75. issue 4. 2000-10-05. PMID:10987842. |
multiple administrations of methamphetamine (meth) rapidly decreased serotonin (5ht) transporter (sert) function in rat striatum and hippocampus. |
2000-10-05 |
2023-08-12 |
rat |
| S Oya, S R Choi, C Hou, M Mu, M P Kung, P D Acton, M Siciliano, H F Kun. 2-((2-((dimethylamino)methyl)phenyl)thio)-5-iodophenylamine (ADAM): an improved serotonin transporter ligand. Nuclear medicine and biology. vol 27. issue 3. 2000-09-26. PMID:10832081. |
serotonin transporters (sert) are target-sites for commonly used antidepressants, such as fluoxetine, paroxetine, sertraline, and so on. |
2000-09-26 |
2023-08-12 |
human |
| C B Boylan, C A Bennett-Clarke, N L Chiaia, R W Rhoade. Time course of expression and function of the serotonin transporter in the neonatal rat's primary somatosensory cortex. Somatosensory & motor research. vol 17. issue 1. 2000-09-26. PMID:10833084. |
immunocytochemical and autoradiographic techniques were employed to determine the time course of expression of the serotonin (5-ht) transporter (sert) on thalamocortical afferents in the rat's primary somatosensory cortex (s-i), and to correlate this expression to the transient vibrissae-related patterning of 5-ht immunostaining previously described. |
2000-09-26 |
2023-08-12 |
rat |
| C B Boylan, C A Bennett-Clarke, N L Chiaia, R W Rhoade. Time course of expression and function of the serotonin transporter in the neonatal rat's primary somatosensory cortex. Somatosensory & motor research. vol 17. issue 1. 2000-09-26. PMID:10833084. |
in additional in vivo and in vitro experiments, 5-ht and 3h-5-ht were applied directly to the cortices of untreated and 5,7-dihydroxytryptamine-treated (5,7-dht) rats in order to determine the period during which sert functions on thalamocortical axons to take up 5-ht. |
2000-09-26 |
2023-08-12 |
rat |
| C B Boylan, C A Bennett-Clarke, N L Chiaia, R W Rhoade. Time course of expression and function of the serotonin transporter in the neonatal rat's primary somatosensory cortex. Somatosensory & motor research. vol 17. issue 1. 2000-09-26. PMID:10833084. |
in postnatal rats, sert immunohistochemistry revealed a somatotopic patterning in s-i that persisted until p-15, which is 6 days after the disappearance of the vibrissae-related 5-ht immunostaining. |
2000-09-26 |
2023-08-12 |
rat |
| C B Boylan, C A Bennett-Clarke, N L Chiaia, R W Rhoade. Time course of expression and function of the serotonin transporter in the neonatal rat's primary somatosensory cortex. Somatosensory & motor research. vol 17. issue 1. 2000-09-26. PMID:10833084. |
the results of these experiments demonstrate that sert is expressed by thalamocortical afferents and remains functional long after the vibrissae-related 5-ht immunostaining in cortex disappears. |
2000-09-26 |
2023-08-12 |
rat |
| B Vollmayr, S Keck, F A Henn, P Schlos. Acute stress decreases serotonin transporter mRNA in the raphe pontis but not in other raphe nuclei of the rat. Neuroscience letters. vol 290. issue 2. 2000-09-21. PMID:10936689. |
since this neurotrophin also controls the efficacy of serotonergic neurotransmission, the aim of the current study was to investigate the effect of acute immobilization stress on the expression of serotonin transporter (sert) mrna in the raphe nuclei as a parameter of serotonergic innervation. |
2000-09-21 |
2023-08-12 |
rat |
| L Zhao, K M Johnson, M Zhang, J Flippen-Anderson, A P Kozikowsk. Chemical synthesis and pharmacology of 6- and 7-hydroxylated 2-carbomethoxy-3-(p-tolyl)tropanes: antagonism of cocaine's locomotor stimulant effects. Journal of medicinal chemistry. vol 43. issue 17. 2000-09-21. PMID:10966747. |
some of these compounds were found to retain considerable affinity as inhibitors of the dopamine transporter (dat) and the norepinephrine transporter (net), but they were less potent inhibitors of the serotonin transporter (sert). |
2000-09-21 |
2023-08-12 |
rat |
| D H Feldman, W R Harvey, B R Steven. A novel electrogenic amino acid transporter is activated by K+ or Na+, is alkaline pH-dependent, and is Cl--independent. The Journal of biological chemistry. vol 275. issue 32. 2000-09-14. PMID:10829035. |
amino acids such as l-proline, l-threonine, and l-methionine elicited complex current-voltage relationships in alkaline ph-dependent caatch1 that were reminiscent of the behavior of the dopamine, serotonin, and norepinephrine transporters (dat, sert, net) in the presence of their substrates and pharmacological inhibitors such as cocaine or antidepressants. |
2000-09-14 |
2023-08-12 |
xenopus_laevis |
| A A Wilson, N Ginovart, M Schmidt, J H Meyer, P G Threlkeld, S Houl. Novel radiotracers for imaging the serotonin transporter by positron emission tomography: synthesis, radiosynthesis, and in vitro and ex vivo evaluation of (11)C-labeled 2-(phenylthio)araalkylamines. Journal of medicinal chemistry. vol 43. issue 16. 2000-09-08. PMID:10956218. |
a series of four 2-(phenylthio)araalkylamines have been radiolabeled with (11)c and evaluated as potential radiotracers for imaging the serotonin transporter (sert) by positron emission tomography (pet). |
2000-09-08 |
2023-08-12 |
human |
| C H van Dyck, R T Malison, J P Seibyl, M Laruelle, H Klumpp, S S Zoghbi, R M Baldwin, R B Inni. Age-related decline in central serotonin transporter availability with [(123)I]beta-CIT SPECT. Neurobiology of aging. vol 21. issue 4. 2000-09-07. PMID:10924762. |
postmortem studies have provided limited and conflicting data regarding aging effects on the central serotonin transporter (sert). |
2000-09-07 |
2023-08-12 |
human |
| Q Saleem, S Ganesh, M Vijaykumar, Y C Reddy, S K Brahmachari, S Jai. Association analysis of 5HT transporter gene in bipolar disorder in the Indian population. American journal of medical genetics. vol 96. issue 2. 2000-09-06. PMID:10893491. |
a variable number tandem repeat (vntr) polymorphism consisting of multiple copies of a 17-bp repeat in the second intron of the serotonin transporter gene (sert) has been reported. |
2000-09-06 |
2023-08-12 |
Not clear |
| F I Tarazi, K Zhang, R J Baldessarin. Olanzapine, quetiapine, and risperidone: long-term effects on monoamine transporters in rat forebrain. Neuroscience letters. vol 287. issue 2. 2000-08-17. PMID:10854717. |
we compared labeling of dopamine (dat) and serotonin (sert) transporter proteins in subregions of rat corpus striatum by quantitative autoradiography with [(3)h]2-beta-carbomethoxy-3-beta-[4'-iodophenyl]tropane ([(3)h]beta-cit) and [(3)h]paroxetine after 28 days of continuous subcutaneous infusion of olanzapine, quetiapine, risperidone, or vehicle controls. |
2000-08-17 |
2023-08-12 |
rat |