| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hideki Mochizuki, Taku Amano, Takahiro Seki, Hiroaki Matsubayashi, Chieko Mitsuhata, Katsuya Morita, Shigeo Kitayama, Toshihiro Dohi, Hiromu K Mishima, Norio Saka. Role of C-terminal region in the functional regulation of rat serotonin transporter (SERT). Neurochemistry international. vol 46. issue 2. 2005-03-09. PMID:15627510. |
previously, we revealed that the state of the actin cytoskeleton affects the uptake activity of the serotonin transporter (sert). |
2005-03-09 |
2023-08-12 |
rat |
| Taleen Hanania, Andrew C McCreary, Danielle O Salaz, Anne M Lyons, Nancy R Zahnise. Differential regulation of cocaine-induced locomotor activity in inbred long-sleep and short-sleep mice by dopamine and serotonin systems. European journal of pharmacology. vol 502. issue 3. 2005-03-08. PMID:15476748. |
in contrast, 5-ht transporter (sert) or 5-ht(1a) receptor antagonists potentiated cocaine-stimulated activity in iss, but not in ils, mice; this potentiation in iss mice was abolished by dopamine d1 receptor blockade. |
2005-03-08 |
2023-08-12 |
mouse |
| A D Dmitriev, E V Pavlova, M I Factor, O L Segal, Yu S Massino, I V Dobrohotov, M B Smirnova, D E Hwun, D A Yakovleva, G I Kolyaskina, O S Bruso. Analysis of serotonin transporter in human platelets by immunoblotting using site-specific antibodies. Biochemistry. Biokhimiia. vol 69. issue 6. 2005-03-07. PMID:15236602. |
we have produced a panel of site-specific antibodies recognizing different regions of the human serotonin transporter (sert). |
2005-03-07 |
2023-08-12 |
human |
| A D Dmitriev, E V Pavlova, M I Factor, O L Segal, Yu S Massino, I V Dobrohotov, M B Smirnova, D E Hwun, D A Yakovleva, G I Kolyaskina, O S Bruso. Analysis of serotonin transporter in human platelets by immunoblotting using site-specific antibodies. Biochemistry. Biokhimiia. vol 69. issue 6. 2005-03-07. PMID:15236602. |
it is possible that one of the cleaved sert species is required for serotonin transport activity. |
2005-03-07 |
2023-08-12 |
human |
| J T Kuikk. Quantitative accuracy of serotonergic neurotransmission imaging with high-resolution 123I SPECT. Nuklearmedizin. Nuclear medicine. vol 43. issue 6. 2005-03-07. PMID:15586213. |
serotonin transporter (sert) imaging can be used to study the role of regional abnormalities of neurotransmitter release in various mental disorders and to study the mechanism of action of therapeutic drugs or drugs' abuse. |
2005-03-07 |
2023-08-12 |
Not clear |
| V E MacDermid, L T McPhail, B Tsang, A Rosenthal, A Davies, M S Rame. A soluble Nogo receptor differentially affects plasticity of spinally projecting axons. The European journal of neuroscience. vol 20. issue 10. 2005-03-01. PMID:15548200. |
serotonergic axons were identified by serotonin (5-ht) or serotonin transporter (sert) immunohistochemistry. |
2005-03-01 |
2023-08-12 |
human |
| Yiyun Huang, Raj Narendran, Sung-A Bae, David Erritzoe, Ningning Guo, Zhihong Zhu, Dah-Ren Hwang, Marc Laruell. A PET imaging agent with fast kinetics: synthesis and in vivo evaluation of the serotonin transporter ligand [11C]2-[2-dimethylaminomethylphenylthio)]-5-fluorophenylamine ([11C]AFA). Nuclear medicine and biology. vol 31. issue 6. 2005-02-25. PMID:15246363. |
a new serotonin transporter (sert) ligand, [11c]2-[2-(dimethylaminomethylphenylthio)]-5-fluorophenylamine (10, [11c]afa), was synthesized and evaluated as a candidate pet radioligand in pharmacological and pharmacokinetic studies. |
2005-02-25 |
2023-08-12 |
rat |
| Yiyun Huang, Raj Narendran, Sung-A Bae, David Erritzoe, Ningning Guo, Zhihong Zhu, Dah-Ren Hwang, Marc Laruell. A PET imaging agent with fast kinetics: synthesis and in vivo evaluation of the serotonin transporter ligand [11C]2-[2-dimethylaminomethylphenylthio)]-5-fluorophenylamine ([11C]AFA). Nuclear medicine and biology. vol 31. issue 6. 2005-02-25. PMID:15246363. |
binding in sert-rich brain regions was reduced significantly by pretreatment with either the cold compound 8 or with the selective serotonin reuptake inhibitor (ssri) citalopram, but not by the selective norepinephrine reuptake inhibitor nisoxetine, thus underlining its in vivo binding selectivity and specificity for sert. |
2005-02-25 |
2023-08-12 |
rat |
| F Scott Hall, Ichiro Sora, Jana Drgonova, Xiao-Fei Li, Michelle Goeb, George R Uh. Molecular mechanisms underlying the rewarding effects of cocaine. Annals of the New York Academy of Sciences. vol 1025. 2005-02-18. PMID:15542699. |
our initial approach to this problem was to combine dat ko mice with serotonin transporter (sert) ko mice to make combined dat/sert ko mice. |
2005-02-18 |
2023-08-12 |
mouse |
| F Scott Hall, Ichiro Sora, Jana Drgonova, Xiao-Fei Li, Michelle Goeb, George R Uh. Molecular mechanisms underlying the rewarding effects of cocaine. Annals of the New York Academy of Sciences. vol 1025. 2005-02-18. PMID:15542699. |
we have also identified evidence that, in the absence of dat, there is greater participation in cocaine reward by serotonin (sert) and norepinephrine (net) transporters. |
2005-02-18 |
2023-08-12 |
mouse |
| Richard B Rothman, Subramaniam Jayanthi, Jean L Cadet, Xiaoying Wang, Christina M Dersch, Michael H Bauman. Substituted amphetamines that produce long-term serotonin depletion in rat brain ("neurotoxicity") do not decrease serotonin transporter protein expression. Annals of the New York Academy of Sciences. vol 1025. 2005-02-18. PMID:15542713. |
administration of high-dose d-fenfluramine (d-fen) or parachloroamphetamine (pca) produces long-lasting decreases in serotonin transporter (sert) binding and tissue levels of serotonin (5-ht) in rat forebrain. |
2005-02-18 |
2023-08-12 |
rat |
| Richard B Rothman, Subramaniam Jayanthi, Jean L Cadet, Xiaoying Wang, Christina M Dersch, Michael H Bauman. Substituted amphetamines that produce long-term serotonin depletion in rat brain ("neurotoxicity") do not decrease serotonin transporter protein expression. Annals of the New York Academy of Sciences. vol 1025. 2005-02-18. PMID:15542713. |
these changes have been viewed as evidence for 5-ht neurotoxicity, but few studies have measured sert protein levels. |
2005-02-18 |
2023-08-12 |
rat |
| Richard B Rothman, Subramaniam Jayanthi, Jean L Cadet, Xiaoying Wang, Christina M Dersch, Michael H Bauman. Substituted amphetamines that produce long-term serotonin depletion in rat brain ("neurotoxicity") do not decrease serotonin transporter protein expression. Annals of the New York Academy of Sciences. vol 1025. 2005-02-18. PMID:15542713. |
despite the large decreases in sert binding and depletion of tissue 5-ht that occurred with d-fen administration, sert protein expression, as determined by western blot analysis, did not change in either tissue or time point. |
2005-02-18 |
2023-08-12 |
rat |
| Richard B Rothman, Subramaniam Jayanthi, Jean L Cadet, Xiaoying Wang, Christina M Dersch, Michael H Bauman. Substituted amphetamines that produce long-term serotonin depletion in rat brain ("neurotoxicity") do not decrease serotonin transporter protein expression. Annals of the New York Academy of Sciences. vol 1025. 2005-02-18. PMID:15542713. |
these results support the hypothesis that d-fen- and pca-induced decreases in tissue 5-ht and sert binding sites reflect neuroadaptive changes rather than neurotoxic effects. |
2005-02-18 |
2023-08-12 |
rat |
| Lesley J Bryan-Lluka, Marisa H Papacostas, Filip A Paczkowski, Janet C Wanstal. Nitric oxide donors inhibit 5-hydroxytryptamine (5-HT) uptake by the human 5-HT transporter (SERT). British journal of pharmacology. vol 143. issue 1. 2005-02-09. PMID:15302679. |
nitric oxide donors inhibit 5-hydroxytryptamine (5-ht) uptake by the human 5-ht transporter (sert). |
2005-02-09 |
2023-08-12 |
mouse |
| Lesley J Bryan-Lluka, Marisa H Papacostas, Filip A Paczkowski, Janet C Wanstal. Nitric oxide donors inhibit 5-hydroxytryptamine (5-HT) uptake by the human 5-HT transporter (SERT). British journal of pharmacology. vol 143. issue 1. 2005-02-09. PMID:15302679. |
the aim was to test the hypothesis that nitric oxide (no) donor drugs can inhibit the 5-hydroxytryptamine (5-ht) transporter, sert. |
2005-02-09 |
2023-08-12 |
mouse |
| Jonathan B Savitz, Rajkumar S Ramesa. Genetic variants implicated in personality: a review of the more promising candidates. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 131B. issue 1. 2005-02-08. PMID:15389772. |
alleles of the serotonin transporter gene (sert) and the dopamine 4 receptor gene (drd4) were first associated with anxiety-related and novelty-seeking personality traits, respectively, in 1996. |
2005-02-08 |
2023-08-12 |
Not clear |
| Jie Huang, Avron D Spier, Virginia M Picke. 5-HT3A receptor subunits in the rat medial nucleus of the solitary tract: subcellular distribution and relation to the serotonin transporter. Brain research. vol 1028. issue 2. 2005-02-04. PMID:15527741. |
to determine the relevant sites for 5-ht3 receptor mediated transmission in this region, we used electron microscopic immunocytochemistry to examine the subcellular distribution of the 5ht3 receptor subunit a (5ht3a) in relation to the serotonin transporter (sert) in the intermediate medial nts (mnts) of rat brain. |
2005-02-04 |
2023-08-12 |
rat |
| Jie Huang, Avron D Spier, Virginia M Picke. 5-HT3A receptor subunits in the rat medial nucleus of the solitary tract: subcellular distribution and relation to the serotonin transporter. Brain research. vol 1028. issue 2. 2005-02-04. PMID:15527741. |
the results further suggest that the neuronal as well as glial 5ht3 receptors can be activated by release of serotonin from presynaptic terminals or by diffusion facilitated by sert distribution at a distant from the synapse. |
2005-02-04 |
2023-08-12 |
rat |
| Fenghua Chen, Mads Breum Larsen, Henrik Amtoft Neubauer, Connie Sánchez, Per Plenge, Ove Wibor. Characterization of an allosteric citalopram-binding site at the serotonin transporter. Journal of neurochemistry. vol 92. issue 1. 2005-02-02. PMID:15606893. |
the serotonin transporter (sert), which belongs to a family of sodium/chloride-dependent transporters, is the major pharmacological target in the treatment of several clinical disorders, including depression and anxiety. |
2005-02-02 |
2023-08-12 |
human |