| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C L Bethea, J M Streicher, S J Mirkes, R L Sanchez, A P Reddy, J L Camero. Serotonin-related gene expression in female monkeys with individual sensitivity to stress. Neuroscience. vol 132. issue 1. 2005-07-20. PMID:15780474. |
in situ hybridization and quantitative image analysis was used to measure mrnas coding for sert (serotonin transporter), 5ht1a autoreceptor, mao-a and mao-b (monoamine oxidases) at six levels of the dorsal raphe nucleus (drn). |
2005-07-20 |
2023-08-12 |
monkey |
| C L Bethea, J M Streicher, S J Mirkes, R L Sanchez, A P Reddy, J L Camero. Serotonin-related gene expression in female monkeys with individual sensitivity to stress. Neuroscience. vol 132. issue 1. 2005-07-20. PMID:15780474. |
thus, all serotonin-related mrnas examined in the dorsal raphe to date were lower (sert, mao-a) or exhibited a lower trend (5ht1a, mao-b) in the stress sensitive animals, which probably reflects the lower number of serotonin neurons present. |
2005-07-20 |
2023-08-12 |
monkey |
| Chi-Chen Wu, Julia Yi-Ru Chen, Pao-Luh Tao, Yi-Ann Chen, Geng-Chang Ye. Serotonin reuptake inhibitors attenuate morphine withdrawal syndrome in neonatal rats passively exposed to morphine. European journal of pharmacology. vol 512. issue 1. 2005-07-19. PMID:15814088. |
previous investigations had shown that inhibitor of serotonin reuptake transporter (sert) could attenuate morphine withdrawal syndrome in adult animals. |
2005-07-19 |
2023-08-12 |
rat |
| Renee F Ren-Patterson, Lauren W Cochran, Andrew Holmes, Suzanne Sherrill, Su-Jan Huang, Teresa Tolliver, Klaus-Peter Lesch, Bai Lu, Dennis L Murph. Loss of brain-derived neurotrophic factor gene allele exacerbates brain monoamine deficiencies and increases stress abnormalities of serotonin transporter knockout mice. Journal of neuroscience research. vol 79. issue 6. 2005-07-15. PMID:15672416. |
to study the neurochemical and behavioral effects of altered brain-derived neurotrophic factor (bdnf) expression on a brain serotonin system with diminished serotonin transport capability, a double-mutant mouse model was developed by interbreeding serotonin transporter (sert) knockout mice with bdnf heterozygous knockout mice (bdnf +/-), producing sert -/- x bdnf +/- (sb) mice. |
2005-07-15 |
2023-08-12 |
mouse |
| Renee F Ren-Patterson, Lauren W Cochran, Andrew Holmes, Suzanne Sherrill, Su-Jan Huang, Teresa Tolliver, Klaus-Peter Lesch, Bai Lu, Dennis L Murph. Loss of brain-derived neurotrophic factor gene allele exacerbates brain monoamine deficiencies and increases stress abnormalities of serotonin transporter knockout mice. Journal of neuroscience research. vol 79. issue 6. 2005-07-15. PMID:15672416. |
prior evidence implicates serotonin and sert in anxiety and stress responses. |
2005-07-15 |
2023-08-12 |
mouse |
| Lankupalle D Jayanthi, Devadoss J Samuvel, Randy D Blakely, Sammanda Ramamoorth. Evidence for biphasic effects of protein kinase C on serotonin transporter function, endocytosis, and phosphorylation. Molecular pharmacology. vol 67. issue 6. 2005-07-14. PMID:15774771. |
the serotonin transporter (sert) regulates 5-hydroxytryptamine (serotonin) (5-ht) neurotransmission and is a high-affinity target for antidepressants and psychostimulants. |
2005-07-14 |
2023-08-12 |
rat |
| Ruth Elizabeth Urwin, Kenneth Patrick Nun. Epistatic interaction between the monoamine oxidase A and serotonin transporter genes in anorexia nervosa. European journal of human genetics : EJHG. vol 13. issue 3. 2005-07-12. PMID:15523490. |
here we provide evidence in support of interaction between the maoa and serotonin transporter (sert) genes in 114 an nuclear families (patient with an plus biological parents). |
2005-07-12 |
2023-08-12 |
Not clear |
| Qian Li, Andrew Holmes, Li Ma, Louis D Van de Kar, Francisca Garcia, Dennis L Murph. Medial hypothalamic 5-hydroxytryptamine (5-HT)1A receptors regulate neuroendocrine responses to stress and exploratory locomotor activity: application of recombinant adenovirus containing 5-HT1A sequences. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 48. 2005-07-12. PMID:15574737. |
our previous studies found that serotonin transporter (sert) knock-out mice showed increased sensitivity to minor stress and increased anxiety-like behavior but reduced locomotor activity. |
2005-07-12 |
2023-08-12 |
mouse |
| William D Schmitz, Derek J Denhart, Allison B Brenner, Jonathan L Ditta, Ronald J Mattson, Gail K Mattson, Thaddeus F Molski, John E Maco. Homotryptamines as potent and selective serotonin reuptake inhibitors (SSRIs). Bioorganic & medicinal chemistry letters. vol 15. issue 6. 2005-07-12. PMID:15745809. |
a series of n,n-dimethylhomotryptamines was prepared and their binding affinities at the serotonin transporter (sert) were determined. |
2005-07-12 |
2023-08-12 |
Not clear |
| Zhihong Zhu, Ningning Guo, Raj Narendran, David Erritzoe, Jesper Ekelund, Dah-Ren Hwang, Sung-A Bae, Marc Laruelle, Yiyun Huan. The new PET imaging agent [11C]AFE is a selective serotonin transporter ligand with fast brain uptake kinetics. Nuclear medicine and biology. vol 31. issue 8. 2005-07-05. PMID:15607480. |
a new positron emission tomography (pet) radioligand for the serotonin transporter (sert), [(11)c]2-[2-[[(dimethylamino)methyl]phenyl]thio]-5-(2-fluoroethyl)phenylamine ([(11)c]afe, 12), was synthesized and evaluated in vivo in rats and baboons. |
2005-07-05 |
2023-08-12 |
rat |
| Xin-Xian Ye, Jeng-Jong Hwang, Jih-Fang Hsieh, Jyh-Cheng Chen, Yueh-Ting Chou, Kao-Yin Tu, Shiaw-Pyng Wey, Gann Tin. In vivo quantification by SPECT of [123I] ADAM bound to serotonin transporters in the brains of rabbits. Nuclear medicine and biology. vol 31. issue 8. 2005-07-05. PMID:15607481. |
a novel radioiodine ligand [(123)i] adam (2-((2-((dimethylamino)methyl)phenyl)thio)-5-iodophenylamine) has been suggested as a promising serotonin transporter (sert) imaging agent for the central nervous system. |
2005-07-05 |
2023-08-12 |
rabbit |
| Ian Morecroft, Lynn Loughlin, Margaret Nilsen, Janet Colston, Yvonne Dempsie, John Sheward, Anthony Harmar, Margaret R MacLea. Functional interactions between 5-hydroxytryptamine receptors and the serotonin transporter in pulmonary arteries. The Journal of pharmacology and experimental therapeutics. vol 313. issue 2. 2005-07-05. PMID:15659538. |
pulmonary arterial 5-hydroxytryptamine (serotonin) (5-ht) transporter (sert)-, 5-ht receptor expression, and 5-ht-induced vasoconstriction can be increased in pulmonary hypertension. |
2005-07-05 |
2023-08-12 |
rat |
| Ian Morecroft, Lynn Loughlin, Margaret Nilsen, Janet Colston, Yvonne Dempsie, John Sheward, Anthony Harmar, Margaret R MacLea. Functional interactions between 5-hydroxytryptamine receptors and the serotonin transporter in pulmonary arteries. The Journal of pharmacology and experimental therapeutics. vol 313. issue 2. 2005-07-05. PMID:15659538. |
sert and 5-ht(1b) expression was greater in fh rat lungs than in sd rats, as was 5-ht-mediated vasoconstriction. |
2005-07-05 |
2023-08-12 |
rat |
| Ian Morecroft, Lynn Loughlin, Margaret Nilsen, Janet Colston, Yvonne Dempsie, John Sheward, Anthony Harmar, Margaret R MacLea. Functional interactions between 5-hydroxytryptamine receptors and the serotonin transporter in pulmonary arteries. The Journal of pharmacology and experimental therapeutics. vol 313. issue 2. 2005-07-05. PMID:15659538. |
sert inhibitors citalopram and fluoxetine inhibited responses to 5-ht in sd vessels. |
2005-07-05 |
2023-08-12 |
rat |
| Ian Morecroft, Lynn Loughlin, Margaret Nilsen, Janet Colston, Yvonne Dempsie, John Sheward, Anthony Harmar, Margaret R MacLea. Functional interactions between 5-hydroxytryptamine receptors and the serotonin transporter in pulmonary arteries. The Journal of pharmacology and experimental therapeutics. vol 313. issue 2. 2005-07-05. PMID:15659538. |
the results suggest that, in fh rats, sert inhibitors may increase pulmonary vasoconstriction, but this can be inhibited by simultaneous 5-ht(1b) receptor antagonism. |
2005-07-05 |
2023-08-12 |
rat |
| Ian Morecroft, Lynn Loughlin, Margaret Nilsen, Janet Colston, Yvonne Dempsie, John Sheward, Anthony Harmar, Margaret R MacLea. Functional interactions between 5-hydroxytryptamine receptors and the serotonin transporter in pulmonary arteries. The Journal of pharmacology and experimental therapeutics. vol 313. issue 2. 2005-07-05. PMID:15659538. |
there is synergy between the inhibitory effects of 5-ht(1b) receptor antagonists and sert inhibitors on 5-ht-induced pulmonary vasoconstriction. |
2005-07-05 |
2023-08-12 |
rat |
| b' Jan Vevera, Zden\\xc4\\x95k Fisar, Tom\\xc3\\xa1s Kvasnicka, Hanus Zdenek, Lucie St\\xc3\\xa1rkov\\xc3\\xa1, Richard Ceska, Hana Papezov\\xc3\\xa. Cholesterol-lowering therapy evokes time-limited changes in serotonergic transmission. Psychiatry research. vol 133. issue 2-3. 2005-06-30. PMID:15740995.' |
serotonin transporter (sert) activity was significantly increased following 1 month of simvastatin; the tendency to decrease the initial increase in sert activity was evident following 2 months of therapy. |
2005-06-30 |
2023-08-12 |
human |
| Laurent Galineau, Catherine Belzung, Ercem Kodas, Sylvie Bodard, Denis Guilloteau, Sylvie Chalo. Prenatal 3,4-methylenedioxymethamphetamine (ecstasy) exposure induces long-term alterations in the dopaminergic and serotonergic functions in the rat. Brain research. Developmental brain research. vol 154. issue 2. 2005-06-27. PMID:15707670. |
prenatally mdma-exposed rats showed (i) a two-fold decrease of whole brain levels of 5-ht and 5-hiaa at p0; (ii) no effect on the dat and sert density; (iii) a strongly reduced pharmacologically induced release of da and 5-ht at p70 in the striatum and hippocampus; and (iv) a significant 20% decrease in sucrose preference at p70. |
2005-06-27 |
2023-08-12 |
rat |
| Nachwa Jarkas, Jonathan McConathy, John R Votaw, Ronald J Voll, Eugene Malveaux, Vernon M Camp, Larry Williams, Robin R Goodman, Clinton D Kilts, Mark M Goodma. Synthesis and characterization of EADAM: a selective radioligand for mapping the brain serotonin transporters by positron emission tomography. Nuclear medicine and biology. vol 32. issue 1. 2005-06-24. PMID:15691664. |
[11c]n,n-dimethyl-2-(2'-amino-4'-ethylphenylthio)benzylamine ([11c]eadam) was synthesized in the development of a serotonin transporter (sert) imaging ligand for positron emission tomography (pet). |
2005-06-24 |
2023-08-12 |
human |
| Chong-Bin Zhu, Ana M Carneiro, Wolfgang R Dostmann, William A Hewlett, Randy D Blakel. p38 MAPK activation elevates serotonin transport activity via a trafficking-independent, protein phosphatase 2A-dependent process. The Journal of biological chemistry. vol 280. issue 16. 2005-06-23. PMID:15728187. |
in contrast, the activity of protein phosphatase 2a inhibitors (fostriecin and calyculin a) to attenuate anisomycin stimulation of 5-ht transport suggests that protein phosphatase 2a is a critical component of the pathway responsible for p38 mapk up-regulation of sert catalytic activity. |
2005-06-23 |
2023-08-12 |
human |