| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chong-Bin Zhu, Randy D Blakely, William A Hewlet. The proinflammatory cytokines interleukin-1beta and tumor necrosis factor-alpha activate serotonin transporters. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 10. 2006-11-01. PMID:16452991. |
in contrast, tnf-alpha stimulation decreased 5-ht km and increased sert vmax. |
2006-11-01 |
2023-08-12 |
mouse |
| Ralf Uebelhack, Leonora Franke, Nathalie Herold, Michael Plotkin, Holger Amthauer, Roland Feli. Brain and platelet serotonin transporter in humans-correlation between [123I]-ADAM SPECT and serotonergic measurements in platelets. Neuroscience letters. vol 406. issue 3. 2006-11-01. PMID:16934400. |
blood platelets are thought to be a useful peripheral model for investigating the central serotoninergic mechanisms associated with the serotonin transporter (sert). |
2006-11-01 |
2023-08-12 |
human |
| J-E Lim, A Papp, J Pinsonneault, W Sadée, D Saffe. Allelic expression of serotonin transporter (SERT) mRNA in human pons: lack of correlation with the polymorphism SERTLPR. Molecular psychiatry. vol 11. issue 7. 2006-10-31. PMID:16432527. |
allelic expression of serotonin transporter (sert) mrna in human pons: lack of correlation with the polymorphism sertlpr. |
2006-10-31 |
2023-08-12 |
human |
| Soili Lehto, Tommi Tolmunen, Mikko Joensuu, Pirjo Irmeli Saarinen, Ritva Vanninen, Pasi Ahola, Jari Tiihonen, Jyrki Kuikka, Johannes Lehtone. Midbrain binding of [123I]nor-beta-CIT in atypical depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 30. issue 7. 2006-10-31. PMID:16644083. |
altered serotonin (sert) and dopamine transporter (dat) densities have been recorded in major depression. |
2006-10-31 |
2023-08-12 |
Not clear |
| b' Nada Bozina, Alma Mihaljevi\\xc4\\x87-Peles, Marina Sagud, Miro Jakovljevi\\xc4\\x87, Jadranka Serti\\xc4\\x8. Serotonin transporter polymorphism in Croatian patients with major depressive disorder. Psychiatria Danubina. vol 18. issue 1-2. 2006-10-27. PMID:16804504.' |
differences in serotonin transporter (sert) expression and function produced by gene polymorphisms are associated with several behavioral and psychiatric traits. |
2006-10-27 |
2023-08-12 |
Not clear |
| F Marte. Recent advances on the importance of the serotonin transporter SERT in the rat intestine. Pharmacological research. vol 54. issue 2. 2006-10-17. PMID:16750380. |
recent advances on the importance of the serotonin transporter sert in the rat intestine. |
2006-10-17 |
2023-08-12 |
rat |
| F Marte. Recent advances on the importance of the serotonin transporter SERT in the rat intestine. Pharmacological research. vol 54. issue 2. 2006-10-17. PMID:16750380. |
intestinal 5-ht is inactivated by metabolic degradation after cellular uptake mediated by the serotonin transporter sert. |
2006-10-17 |
2023-08-12 |
rat |
| F Marte. Recent advances on the importance of the serotonin transporter SERT in the rat intestine. Pharmacological research. vol 54. issue 2. 2006-10-17. PMID:16750380. |
moreover, we also conclude that inhibition of sert causes an increase in transmural transport of 5-ht in these three intestinal segments, probably because it increases the extracellular concentration of 5-ht. |
2006-10-17 |
2023-08-12 |
rat |
| Nader N Youssef, Carlo Di Lorenz. Pediatric gastrointestinal motility--future directions and challenges. Digestive diseases (Basel, Switzerland). vol 24. issue 3-4. 2006-10-17. PMID:16849858. |
experiments studying polymorphisms in serotonin transporter gene (sert) and different therapeutic responses to serotonergic agents in adults with irritable bowel syndrome need to be carried out in children with functional bowel disorders. |
2006-10-17 |
2023-08-12 |
Not clear |
| Fanxing Zeng, Nachwa Jarkas, Michael J Owens, Clinton D Kilts, Charles B Nemeroff, Mark M Goodma. Synthesis and monoamine transporter affinity of front bridged tricyclic 3beta-(4'-halo or 4'-methyl)phenyltropanes bearing methylene or carbomethoxymethylene on the bridge to the 2beta-position. Bioorganic & medicinal chemistry letters. vol 16. issue 17. 2006-10-16. PMID:16784855. |
a series of front bridged tricyclic 3beta-(4'-halo or 4'-methyl)phenyltropanes bearing methylene or carbomethoxymethylene on the bridge to the 2beta-position was synthesized, and their binding affinities were determined in cells transfected to express human norepinephrine transporter (net), serotonin transporter (sert), and dopamine transporter (dat) via competition binding assays. |
2006-10-16 |
2023-08-12 |
human |
| Robert Adamec, Paul Burton, Jacqueline Blundell, Dennis L Murphy, Andrew Holme. Vulnerability to mild predator stress in serotonin transporter knockout mice. Behavioural brain research. vol 170. issue 1. 2006-10-11. PMID:16546269. |
there is a link between genetic variation in the serotonin (5-ht) transporter (sert) and anxiety in humans. |
2006-10-11 |
2023-08-12 |
mouse |
| Elisabeth D Willers, John H Newman, James E Loyd, Ivan M Robbins, Lisa A Wheeler, Melissa A Prince, Krista C Stanton, Joy A Cogan, James R Runo, Daniel Byrne, Marc Humbert, Gerald Simonneau, Benjamin Sztrymf, Jane A Morse, James A Knowles, Kari E Roberts, Jude J McElroy, Robyn J Barst, John A Phillip. Serotonin transporter polymorphisms in familial and idiopathic pulmonary arterial hypertension. American journal of respiratory and critical care medicine. vol 173. issue 7. 2006-10-03. PMID:16339917. |
the serotonin transporter (sert) is abundant in pulmonary vascular smooth muscle. |
2006-10-03 |
2023-08-12 |
human |
| Linda Ferrington, Eszter Kirilly, Douglas E McBean, Henry J Olverman, György Bagdy, Paul A T Kell. Persistent cerebrovascular effects of MDMA and acute responses to the drug. The European journal of neuroscience. vol 24. issue 2. 2006-10-03. PMID:16836637. |
three weeks after mdma pre-treatment there were significant reductions in densities of 5-ht transporter (sert)-positive fibres (-46%) and [(3)h]-paroxetine binding (-47%). |
2006-10-03 |
2023-08-12 |
rat |
| Kun-Ju Lin, Chia-Yih Liu, Shiaw-Pyng Wey, Ing-Tsung Hsiao, Jay Wu, Ying-Kai Fu, Tzu-Chen Ye. Brain SPECT imaging and whole-body biodistribution with [(123)I]ADAM - a serotonin transporter radiotracer in healthy human subjects. Nuclear medicine and biology. vol 33. issue 2. 2006-09-28. PMID:16546673. |
[(123)i]-2-((2-((dimethylamino)methyl)phenyl)thio)-5-iodophenylamine ([(123)i]adam), a novel radiotracer, has promising application in the imaging of the serotonin transporter (sert) in the human brain. |
2006-09-28 |
2023-08-12 |
human |
| Jean-Marie Launay, Benoit Schneider, Sylvain Loric, Mose Da Prada, Odile Kellerman. Serotonin transport and serotonin transporter-mediated antidepressant recognition are controlled by 5-HT2B receptor signaling in serotonergic neuronal cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 20. issue 11. 2006-09-18. PMID:16940156. |
the plasma membrane 5-ht transporter (sert) is the major protagonist in regulating extracellular 5-ht concentration and constitutes the target of drugs used to treat a host of metabolic and psychiatric disorders. |
2006-09-18 |
2023-08-12 |
Not clear |
| Jean-Marie Launay, Benoit Schneider, Sylvain Loric, Mose Da Prada, Odile Kellerman. Serotonin transport and serotonin transporter-mediated antidepressant recognition are controlled by 5-HT2B receptor signaling in serotonergic neuronal cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 20. issue 11. 2006-09-18. PMID:16940156. |
because external 5-ht reduces both 5-ht transport and sert antidepressant binding, we identify 5-ht(2b) receptors as key players in controlling the overall 5-ht transport system. |
2006-09-18 |
2023-08-12 |
Not clear |
| Jean-Marie Launay, Benoit Schneider, Sylvain Loric, Mose Da Prada, Odile Kellerman. Serotonin transport and serotonin transporter-mediated antidepressant recognition are controlled by 5-HT2B receptor signaling in serotonergic neuronal cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 20. issue 11. 2006-09-18. PMID:16940156. |
in the absence of external 5-ht, 5-ht(2b) receptor coupling to no production ensures sert phosphorylation to basal level and maximal 5-ht uptake. |
2006-09-18 |
2023-08-12 |
Not clear |
| Jean-Marie Launay, Benoit Schneider, Sylvain Loric, Mose Da Prada, Odile Kellerman. Serotonin transport and serotonin transporter-mediated antidepressant recognition are controlled by 5-HT2B receptor signaling in serotonergic neuronal cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 20. issue 11. 2006-09-18. PMID:16940156. |
in the presence of 5-ht, the 5-ht(2b) receptor-pkc coupling promotes additional phosphorylations of both sert and na(+),k(+)-atpase alpha-subunit, impairing the electrochemical gradient necessary to 5-ht uptake. |
2006-09-18 |
2023-08-12 |
Not clear |
| Jean-Marie Launay, Benoit Schneider, Sylvain Loric, Mose Da Prada, Odile Kellerman. Serotonin transport and serotonin transporter-mediated antidepressant recognition are controlled by 5-HT2B receptor signaling in serotonergic neuronal cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 20. issue 11. 2006-09-18. PMID:16940156. |
finally, such 5-ht(2b) receptor-mediated control of sert activity operates in primary neurons from raphe nuclei. |
2006-09-18 |
2023-08-12 |
Not clear |
| Rong Chen, Michael R Tilley, Hua Wei, Fuwen Zhou, Fu-Ming Zhou, San Ching, Ning Quan, Robert L Stephens, Erik R Hill, Timothy Nottoli, Dawn D Han, Howard H G. Abolished cocaine reward in mice with a cocaine-insensitive dopamine transporter. Proceedings of the National Academy of Sciences of the United States of America. vol 103. issue 24. 2006-09-11. PMID:16754872. |
there are three known high-affinity targets for cocaine: the dopamine transporter (dat), the serotonin transporter (sert), and the norepinephrine transporter (net). |
2006-09-11 |
2023-08-12 |
mouse |