| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yongjin Mao, Chen Su, Huilin Yang, Xiaocong Ma, Feng Zhao, Bo Qu, Yang Yang, Xiaoming Hou, Bing Zhao, Yingjun Cu. PI3K/AKT/mTORC1 signalling pathway regulates Animal biotechnology. 2024-02-12. PMID:38343377. |
pi3k/akt/mtorc1 signalling pathway regulates matrix metalloproteinase 9 (mmp9) plays a pivotal role in mammary ductal morphogenesis, angiogenesis and glandular tissue architecture remodeling. |
2024-02-12 |
2024-02-15 |
Not clear |
| Sohini Kulavi, Debajit Dhar, Izaz Monir Kamal, Saikat Chakrabarti, Jaya Bandyopadhya. EIF4A3 targeted therapeutic intervention in glioblastoma multiforme using phytochemicals from Indian medicinal plants - an integration of phytotherapy into precision onco-medicine. Journal of biomolecular structure & dynamics. 2024-02-12. PMID:38345073. |
eif4a3 promotes the expression of several non-coding rnas, viz, circ matrix metallopeptidase 9 (mmp9), a prominent oncogene, by interacting with the upstream region of the circmmp9 mrna transcript and acts on cell proliferation, migration, and invasion of gbm. |
2024-02-12 |
2024-02-15 |
Not clear |
| Feixiang Luo, Mingqian Li, Yuguo Chen, Shifei Song, Haiyang Yu, Peng Zhang, Chunsheng Xiao, Guoyue Lv, Xuesi Che. Immunosuppressive enzyme-responsive nanoparticles for enhanced accumulation in liver allograft to overcome acute rejection. Biomaterials. vol 306. 2024-01-24. PMID:38266349. |
the nanoparticles are composed of amphiphilic tacrolimus prodrugs synthesized by covalently conjugating tacrolimus and matrix metalloproteinase 9 (mmp9)-cleavable peptide-containing methoxy poly (ethylene glycol) to poly (l-glutamic acid). |
2024-01-24 |
2024-01-27 |
rat |
| Hong Su, Qiuju Yan, Wei Du, En Hu, Zhaoyu Yang, Wei Zhang, Yusheng Li, Tao Tang, Shushan Zhao, Yang Wan. Calycosin ameliorates osteoarthritis by regulating the imbalance between chondrocyte synthesis and catabolism. BMC complementary medicine and therapies. vol 24. issue 1. 2024-01-23. PMID:38254101. |
while cartilage matrix degradation index cyclooxygenase-2 (cox-2), phosphor-epidermal growth factor receptor (p-egfr), and matrix metalloproteinase-9 (mmp9) expression were decreased. |
2024-01-23 |
2024-01-25 |
mouse |
| Qing Lv, Qianqian Han, Ziyun Wen, Yunyun Pan, Jisheng Che. The association between atherosclerosis and nonalcoholic fatty liver disease. Medicine. vol 103. issue 1. 2024-01-05. PMID:38181273. |
according to the results of an analysis of common genes, matrix metalloproteinase 9 (mmp9) is co-expressed up-regulated in as and nafld and is enriched in inflammatory and immune-related collaterals. |
2024-01-05 |
2024-01-08 |
Not clear |
| Li Cai, Xiaoyu Zuo, Liuheyi Ma, Yuxia Zhang, Falin Xu, Bingtai L. Associations of MMP9 polymorphism with the risk of severe pneumonia in a Southern Chinese children population. BMC infectious diseases. vol 24. issue 1. 2024-01-03. PMID:38166679. |
matrix metallopeptidase 9 (mmp9) is a zinc-dependent endopeptidase that is involved in various cellular processes. |
2024-01-03 |
2024-01-06 |
Not clear |
| Liyue Li, Linyi Jiao, Danni Feng, Yizhang Yuan, Xiaoqian Yang, Jian Li, Dong Jiang, Hexin Chen, Qingxiang Meng, Ruchong Chen, Bixing Fang, Xuenong Zou, Zhenhua Luo, Xiaoyan Ye, Yue Hong, Chun Liu, Chunwei L. Human apical-out nasal organoids reveal an essential role of matrix metalloproteinases in airway epithelial differentiation. Nature communications. vol 15. issue 1. 2024-01-03. PMID:38168066. |
the expression and activity of ecm-degrading enzymes, matrix metalloproteinases (mmp7, mmp9, mmp10 and mmp13) increases during organoid differentiation, where inhibition of mmps significantly suppresses the normal ciliation, resulting in increased goblet cell proportion. |
2024-01-03 |
2024-01-06 |
human |
| Chengjun Hu, Fengjie Ji, Renlong Lv, Hanlin Zhou, Guanyu Hou, Tieshan X. Putrescine promotes MMP9-induced angiogenesis in skeletal muscle through hydrogen peroxide/METTL3 pathway. Free radical biology & medicine. 2023-12-30. PMID:38159892. |
furthermore, putrescine was found to promote angiogenesis in skeletal muscle both in vitro and in vivo by targeting matrix metalloproteinase 9 (mmp9). |
2023-12-30 |
2024-01-05 |
Not clear |
| Yixia Li, Xiaorong Zhong, Feng Yan. Silencing HE4 alleviates the renal fibrosis in lupus nephritis mice by regulating the C3/MMPs/prss axis. Naunyn-Schmiedeberg's archives of pharmacology. 2023-12-29. PMID:38157023. |
western blotting was used to determine the levels of c3, he4, matrix metalloproteinase-2 (mmp2), mmp9, p-p65, prss23, and prss35 in renal tissues. |
2023-12-29 |
2024-01-05 |
mouse |
| Haixia Ming, Ming Shen, Yanwen Chen, Yang Li, Lingling Yang, Qiankun Liang, Zhaohua Li. [Establishment and evaluation of pre-metastatic niche mouse model labelled with luciferase in lewis lung cancer cells]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 39. issue 12. 2023-12-23. PMID:38140867. |
real-time quantitative pcr and western blot analysis were used to detect the mrna and protein expression of lysyl oxidase (lox), matrix metalloproteinase 9 (mmp9), versican (vcan), and fibronectin (fn), which are the specific markers for the formation of the microenvironment of lung tissues before metastasis. |
2023-12-23 |
2023-12-25 |
mouse |
| Jie Mei, Jing Zuo, Jiazhuan Mei, Guiju Liu, Peng Xia. Circ-NUP98 Promotes Lung Adenocarcinoma Development Through Regulating CBX1 by miR-188-3p. Biochemical genetics. 2023-12-22. PMID:38129720. |
cyclind1, bcl-2-related x protein (bax), matrix metalloproteinase 9 (mmp9) protein, and cbx1 protein levels were determined using western blot. |
2023-12-22 |
2023-12-24 |
human |
| Xiao-Qin Zhong, Da-Feng Hu, Yu Wang, Zhen-Qiu Ning, Min-Zhen Den. [Mechanism of Zhongfeng Xingnao Decoction in improving microcirculatory disorders in cerebral hemorrhage based on network pharmacology and molecular docking techniques]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 22. 2023-12-19. PMID:38114219. |
the results revealed that the zfxn relieved the neural injury in mice with cerebral hemorrhage, decreased the expression of s100 calcium-binding protein b(s100β), neuron specific enolase(nse), matrix metalloproteinase 9(mmp9), tumor necrosis factor α(tnf-α), interleukin 1β(il-1β), src, egfr, ctnnb1, vegfa, tp53, glial fibrillary acidic protein(gfap), and leukocyte differentiation antigen 86(cd86), and increased the expression of p-pi3k, p-akt, and zona occludens 1(zo-1). |
2023-12-19 |
2023-12-23 |
mouse |
| Yuchen Ge, Man Li, Shirui Bai, Cui Chen, Shulin Zhang, Jiamao Cheng, Xiaobo Wan. Doxercalciferol alleviates UVB-induced HaCaT cell senescence and skin photoaging. International immunopharmacology. vol 127. 2023-12-17. PMID:38104366. |
then, we found that the senescence β-galactosidase (sa-β-gal) positive rate, senescence-related protein (p16), aging-related genes (p21 and p53), senescence-associated secretory phenotype (sasp), inflammatory driving factors (il-1β and il-6) and matrix metalloproteinases (mmps) (mmp1 and mmp9) were upregulated in hacat cells after uvb irradiation. |
2023-12-17 |
2023-12-21 |
mouse |
| Suryaa Manoharan, Shreejit Saha, Krishnasanthiya Murugesan, Aksayakeerthana Santhakumar, Ekambaram Peruma. Natural bioactive compounds and STAT3 against hepatocellular carcinoma: An update. Life sciences. 2023-12-16. PMID:38103726. |
further, through stat3 inhibition, terpenes downregulate matrix metalloprotease 2 (mmp2), matrix metalloprotease 9 (mmp9) and vascular endothelial growth factor (vegf), modulating metastasis. |
2023-12-16 |
2023-12-21 |
Not clear |
| Craig A Erickson, Rebecca C Shaffer, Meredith Will, Lauren M Schmitt, Paul Horn, Kathy Hirst, Ernest V Pedapati, Nicole Ober, Rameshwari V Tumuluru, Benjamin L Handen, David Q Beversdor. Brief Report: A Double-Blind, Placebo-Controlled, Crossover, Proof-of-Concept Study of Minocycline in Autism Spectrum Disorder. Journal of autism and developmental disorders. 2023-12-15. PMID:38102393. |
minocycline is a matrix metalloproteinase inhibitor 9 (mmp9) inhibitor tetracycline antibiotic with known anti-inflammatory properties. |
2023-12-15 |
2023-12-18 |
human |
| Hiroki Hashizume, Hatsune Motonari, Kenta Yamamoto, Yoki Nakamura, Kazue Hisaoka-Nakashima, Norimitsu Moriok. Stimulation of nuclear receptor REV-ERBs alleviates monosodium iodoacetate-induced osteoarthritis pathology of mice and the induction of inflammatory molecules expression in primary cultured chondrocytes. International immunopharmacology. vol 127. 2023-12-12. PMID:38086272. |
in the current study, we found that pretreatment with the rev-erb agonist sr9009 significantly blocked the increases in inflammatory molecules [(matrix metalloproteinase (mmp) 3, mmp9, and mmp13] and cytokines (interleukin-1β and tumor necrosis factor) in primary cultured chondrocytes following treatment with lipopolysaccharide. |
2023-12-12 |
2023-12-17 |
mouse |
| Ye Ji Kim, Zinah Hilal Khaleel, Myeongji Jin, Jo Woon Yi Lee, Seongchan Park, Seongmin Ga, Nam Hyeong Kim, Deok Hyang Sa, Eun Sung Kang, Seul Hee Han, Ji Yeun Lee, Hyo Jung Ku, Sang-Wook Kim, Ki Yong Kim, Jeong Euy Park, Yong Ho Kim, Bok-Soo Le. Mechanistic insights into the anti-restenotic effects of HSP27 and HO1 modulated by reconstituted HDL on neointimal hyperplasia. Scientific reports. vol 13. issue 1. 2023-12-12. PMID:38087008. |
additionally, rhdl treatment led to decreased infiltration of leukocytes and downregulated the expression of matrix metallopeptidase 9 (mmp9) in the neointimal area. |
2023-12-12 |
2023-12-17 |
rat |
| Xiangrong Liu, Wenqi Bai, Jianrong Li, Jinfeng Ma, Yan Liu, Zhixiang Wang, Linjie Hu, Zheng Li, Dimitri Papukashvili, Nino Rcheulishvili, Fusheng Wang, Xiaoqing L. MLLT11 siRNA Inhibits the Migration and Promotes the Apoptosis of MDA-MB-231 Breast Cancer Cells. The breast journal. vol 2023. 2023-12-11. PMID:38075552. |
moreover, cell migration and invasion, as well as the protein levels of phosphatidylinositol 3-kinase (pi3k), akt, matrix metalloproteinase (mmp) 2, and mmp9, were significantly lower in the groups treated with sirna while the apoptosis was augmented. |
2023-12-11 |
2023-12-17 |
Not clear |
| Xiaoyan Shen, Xiaoping Xie, Qi Wu, Feng Shi, Yuanyang Chen, Shun Yuan, Kai Xing, Xu Li, Qingyi Zhu, Bowen Li, Zhiwei Wan. S-adenosylmethionine attenuates angiotensin II-induced aortic dissection formation by inhibiting vascular smooth muscle cell phenotypic switch and autophagy. Biochemical pharmacology. vol 219. 2023-12-10. PMID:38065291. |
meanwhile, sam also inhibited the cellular phenotypic switch, mainly by up regulating the expression levels of contractile marker proteins [α-smooth muscle actin (α-sma) and smooth muscle 22α (sm22α)] and down regulating the expression levels of synthetic marker proteins [osteoblast protein (opn), matrix metalloproteinase-2 (mmp2), and matrix metalloproteinase-9 (mmp9)]. |
2023-12-10 |
2023-12-17 |
mouse |
| Rotem Kalev-Altman, Gal Becker, Tamar Levy, Svetlana Penn, Nahum Y Shpigel, Efrat Monsonego-Ornan, Dalit Sela-Donenfel. Mmp2 Deficiency Leads to Defective Parturition and High Dystocia Rates in Mice. International journal of molecular sciences. vol 24. issue 23. 2023-12-09. PMID:38069145. |
the gelatinases subgroup of matrix metalloproteinases (mmps), mmp2 and mmp9, participate in uterine ecm remodeling throughout pregnancy and parturition. |
2023-12-09 |
2023-12-17 |
mouse |