| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Haoxiao Chang, Jia Ma, Kai Feng, Ning Feng, Xinxin Wang, Jiali Sun, Tianshu Guo, Yuzhen Wei, Yun Xu, Huabing Wang, Linlin Yin, Xinghu Zhan. Elevated blood and cerebrospinal fluid biomarkers of microglial activation and blood‒brain barrier disruption in anti-NMDA receptor encephalitis. Journal of neuroinflammation. vol 20. issue 1. 2023-07-22. PMID:37481571. |
matrix metalloproteinase-9 (mmp9) and cluster of differentiation (cd44) were measured to evaluate blood‒brain barrier (bbb) permeability in anti-nmdar encephalitis. |
2023-07-22 |
2023-08-14 |
Not clear |
| Marjan Boshev, Svetlana Stankovic, Sasho Panov, Slavica Josifovska, Antonio Georgiev, Lidija Poposka, Hristo Pejko. Association of the Polymorphism rs3918242 of the Matrix Metalloproteinase-9 Gene with Coronary Artery Disease in a Younger Population. Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki). vol 44. issue 2. 2023-07-15. PMID:37453108. |
the aim of this study is to investigate the association of the rs3918242 polymorphism of the matrix metal-loproteinase 9 (mmp9) gene with the coronary artery disease in the younger population. |
2023-07-15 |
2023-08-14 |
Not clear |
| María Luisa Hernández-Bule, Elena Toledano-Macías, Luis Alfonso Pérez-González, María Antonia Martínez-Pascual, Montserrat Fernández-Guarin. Anti-Fibrotic Effects of RF Electric Currents. International journal of molecular sciences. vol 24. issue 13. 2023-07-14. PMID:37446165. |
furthermore, in these cultures the expression and/or localization of extracellular matrix proteins such as α-sma, col i, col iii (immunofluorescence), metalloproteinases mmp1 and mmp9, map kinase erk1/2, and the transcription factor nfκb were also investigated (immunoblot). |
2023-07-14 |
2023-08-14 |
human |
| María Luisa Hernández-Bule, Elena Toledano-Macías, Luis Alfonso Pérez-González, María Antonia Martínez-Pascual, Montserrat Fernández-Guarin. Anti-Fibrotic Effects of RF Electric Currents. International journal of molecular sciences. vol 24. issue 13. 2023-07-14. PMID:37446165. |
the results have revealed that cret decreases the expression of extracellular matrix proteins, modifies the expression of the metalloproteinase mmp9, and reduces the activation of nfκb with respect to controls, suggesting that this therapy could be useful for the treatment of fibrotic pathologies. |
2023-07-14 |
2023-08-14 |
human |
| Nizar Ahmed, Devi Aru. Matrix Metalloproteinase Activity in Gingival Crevicular Fluid and Periodontal Health Status in Down Syndrome Patients: A Comparative Study. Cureus. vol 15. issue 6. 2023-07-14. PMID:37448427. |
we collected patients' complete case histories and blood samples for evaluating matrix metalloproteinase 8 (mmp8) and matrix metalloproteinase 9 (mmp9) levels. |
2023-07-14 |
2023-08-14 |
human |
| Nanees Elmalkey, Mohammed Aref, Nehal Goda, Marwa Hussien, Walaa Samy, Shimaa Hadho. Sleep Deprivation Disturbs Uterine Contractility and Structure in Pregnant Rats: Role of Matrix Metalloproteinase 9 and Transforming Growth Factor-β. Canadian journal of physiology and pharmacology. 2023-07-11. PMID:37433223. |
matrix metalloproteinase-9 (mmp9) and transforming growth factor-β (tgf-β) are regulators of uterine remodeling. |
2023-07-11 |
2023-08-14 |
rat |
| Frangky Sangande, Kurnia Agustini, Krisyanti Budipraman. Antihyperlipidemic mechanisms of a formula containing Curcuma xanthorrhiza, Sechium edule, and Syzigium polyanthum: In silico and in vitro studies. Computational biology and chemistry. vol 105. 2023-07-01. PMID:37392529. |
based on the topology parameters, we identified 6 significant targets that play an important role in reducing lipid serum levels: hmg-coa reductase (hmgcr), peroxisome proliferator-activated receptor alpha (ppara), rac-alpha serine/threonine-protein kinase (akt1), epidermal growth factor receptor (egfr), matrix metalloproteinase-9 (mmp9), and tumor necrosis factor-alpha (tnf). |
2023-07-01 |
2023-08-14 |
Not clear |
| Van-Hai Hoang, Nguyen Thi Kieu Trang, Truong Cao Minh, Le Thien Bao Long, Tran Hoang Lan, Nguyen Thi Hue, Le Quoc Tien, Thanh Xuan Nguyen, Yen Thi Kim Nguyen, Hoon Yoo, Phuong-Thao Tra. Design, synthesis and evaluation the bioactivities of novel 1,3-dimethyl-6-amino-1H-indazole derivatives as anticancer agents. Bioorganic & medicinal chemistry. vol 90. 2023-06-23. PMID:37352576. |
finally, compound 7 suppressed cell mobility in wound healing assay with the reduced expression of matrix metalloproteinase mmp9. |
2023-06-23 |
2023-08-14 |
human |
| Giovanna Casili, Sarah Adriana Scuderi, Marika Lanza, Alessia Filippone, Deborah Mannino, Raffaella Giuffrida, Cristina Colarossi, Marzia Mare, Anna Paola Capra, Federica De Gaetano, Marco Portelli, Angela Militi, Salvatore Cuzzocrea, Irene Paterniti, Emanuela Esposit. Therapeutic Potential of BAY-117082, a Selective NLRP3 Inflammasome Inhibitor, on Metastatic Evolution in Human Oral Squamous Cell Carcinoma (OSCC). Cancers. vol 15. issue 10. 2023-06-22. PMID:37345134. |
additionally, bay-117082 treatment modulated the epithelial-mesenchymal transition (emt) process in tongue tissue as well as in metastatic organs such as lymph node, lung, and spleen, also reducing the expression of matrix metalloproteinases (mmps), particularly mmp2 and mmp9, markers of cell invasion and migration. |
2023-06-22 |
2023-08-14 |
human |
| Weiwei Zheng, Yingchang Guo, Guangtan Zhang, Junwei Bai, Yucheng Song, Xiaofei Song, Qinhui Zhu, Xuebin Bao, Gang Wu, Chao Zhan. Peptide encoded by lncRNA BVES-AS1 promotes cell viability, migration, and invasion in colorectal cancer cells via the SRC/mTOR signaling pathway. PloS one. vol 18. issue 6. 2023-06-22. PMID:37347740. |
immunofluorescence assay showed that bves-as1-201-50aa increased the expression of proliferating cell nuclear antigen (pcna) and matrix metalloproteinase 9 (mmp9) in crc cells. |
2023-06-22 |
2023-08-14 |
human |
| Dina Moustafa Abou Rayia, Batoul M Izzularab, Samar Harras, Muhammad Tarek Abdel Ghafar, Asmaa Ramadan Azzam, Heba Harras, Reham Lotfy Younis, Shaimaa Soliman, Abeer Ezzat Saa. Stem cell biotherapy: A new remedy for Trichinella spiralis-induced inflammatory myopathy. Parasitology international. 2023-06-17. PMID:37330041. |
additionally, serum muscle enzymes creatine kinase (ck) and lactate dehydrogenase (ldh), as well as muscle matrix metalloproteinases mmp1 and mmp9, were assayed. |
2023-06-17 |
2023-08-14 |
rat |
| Shreemoyee De, Neetu Sing. Collagen-alginate 3D microscaffolds for studying cellular migration. International journal of biological macromolecules. 2023-06-14. PMID:37315661. |
the platform's ability to allow observation of cellular migration was validated by encapsulating cells with transiently upregulated matrix metalloprotease 9 (mmp9), which has been reported to play a significant role in migration of cells during metastasis. |
2023-06-14 |
2023-08-14 |
Not clear |
| Shuichi Tsukamoto, Yu-Ichiro Koma, Yu Kitamura, Kohei Tanigawa, Yuki Azumi, Shoji Miyako, Satoshi Urakami, Masayoshi Hosono, Takayuki Kodama, Mari Nishio, Manabu Shigeoka, Hiroshi Yokozak. Matrix Metalloproteinase 9 Induced in Esophageal Squamous Cell Carcinoma Cells via Close Contact with Tumor-Associated Macrophages Contributes to Cancer Progression and Poor Prognosis. Cancers. vol 15. issue 11. 2023-06-11. PMID:37296952. |
we found that matrix metalloproteinase 9 (mmp9) was induced in escc cells by direct co-culture with tams, not by indirect co-culture. |
2023-06-11 |
2023-08-14 |
Not clear |
| Di Hu, Zenan Lin, Pan Li, Zhehuan Zhang, Junhong Jiang, Chenhao Yan. Investigation of Potential Crucial Genes and Key Pathways in Keratoconus: An Analysis of Gene Expression Omnibus Data. Biochemical genetics. 2023-05-26. PMID:37233843. |
the results revealed that extracellular matrix remodeling and immune inflammatory response could be the key links of keratoconus, tnf, il6, il1a, il1b, ccl3, mmp3, mmp9, mmp1, and tgfb1 may be potential crucial genes, and tnf signaling pathway and il-17 signaling pathway were the potential pathways accounting for pathogenesis and development of keratoconus. |
2023-05-26 |
2023-08-14 |
Not clear |
| Lihong Shi, Qiangsheng Zhang, Shirui Zhu, Qing Tang, Xin Chen, Rui Lan, Ningyu Wang, Yongxia Zh. Pharmacological inhibition of EZH2 using a covalent inhibitor suppresses human ovarian cancer cell migration and invasion. Molecular and cellular biochemistry. 2023-05-18. PMID:37199893. |
enhancer of zeste homolog 2 (ezh2), a histone-lysine n-methyltransferase enzyme, promotes oc cell migration and invasion by regulating the expression of tissue inhibitor of metalloproteinase-2 (timp2) and matrix metalloproteinases-9 (mmp9). |
2023-05-18 |
2023-08-14 |
human |
| Huixian Zheng, Chaoyi Hu, Yunyun Quan, Xiaoxia Ye, Xiangchao Shi, Zijian Guo, Xiaoyong Wan. A copper complex that combats triple negative breast cancer by restraining angiogenesis. Dalton transactions (Cambridge, England : 2003). 2023-05-17. PMID:37195167. |
moreover, cpt8 suppressed the expression of vascular endothelial cadherin and matrix metalloproteinases mmp2 and mmp9, leading to the inhibition of vasculogenic mimicry formation. |
2023-05-17 |
2023-08-14 |
human |
| Zhimin Shen, Peipei Zhang, Weiguang Zhang, Fei Luo, Hui Xu, Shuchen Chen, Mingqiang Kan. IL-1RA inhibits esophageal carcinogenesis and lymphangiogenesis via downregulating VEGF-C and MMP9. Functional & integrative genomics. vol 23. issue 2. 2023-05-17. PMID:37198330. |
il-1ra inhibits lymph node metastasis of escc by regulating the emt through activation of matrix metalloproteinase 9(mmp9) and lymphangiogenesis, driven by vegf-c and the nf-κb signaling pathway. |
2023-05-17 |
2023-08-14 |
Not clear |
| Satoru Shindo, Roodelyne Pierrelus, Atsushi Ikeda, Shin Nakamura, Alireza Heidari, Maria Rita Pastore, Elizabeth Leon, Sunniva Ruiz, Harsh Chheda, Rhea Khatiwala, Tomoki Kumagai, George Tolson, Islam Elderbashy, Kazuhisa Ouhara, Xiaozhe Han, Maria Hernandez, Saynur Vardar-Sengul, Hideki Shiba, Toshihisa Kawa. Extracellular Release of Citrullinated Vimentin Directly Acts on Osteoclasts to Promote Bone Resorption in a Mouse Model of Periodontitis. Cells. vol 12. issue 8. 2023-05-16. PMID:37190018. |
the cv-induced upregulation of oc-genesis was abrogated by the protein kinase c (pkc)-δ inhibitor rottlerin, accompanied by the downmodulation of oc-genesis-related genes, including osteoclast stimulatory transmembrane protein (oc-stamp), trap and matrix metallopeptidase 9 (mmp9) as well as extracellular signal-regulated kinase (erk) mitogen-activated protein (map)-kinase phosphorylation. |
2023-05-16 |
2023-08-14 |
mouse |
| Noureldien H E Darwish, Khaled A Hussein, Khaled Elmasry, Ahmed S Ibrahim, Julia Humble, Mohamed Moustafa, Fatma Awadalla, Mohamed Al-Shabrawe. Bone Morphogenetic Protein-4 Impairs Retinal Endothelial Cell Barrier, a Potential Role in Diabetic Retinopathy. Cells. vol 12. issue 9. 2023-05-14. PMID:37174679. |
the impact of bmp4 on matrix metalloproteinases (mmp2 and mmp9) was also evaluated using specific elisa kits. |
2023-05-14 |
2023-08-14 |
mouse |
| S Banerjee, S K Baidya, B Ghosh, T Jha, N Adhikar. Exploration of structural alerts and fingerprints for novel anticancer therapeutics: a robust classification-QSAR dependent structural analysis of drug-like MMP-9 inhibitors. SAR and QSAR in environmental research. 2023-05-12. PMID:37170840. |
among various matrix metalloproteinases (mmps), overexpression of mmp9 has been established as a key player in a variety of cancers. |
2023-05-12 |
2023-08-14 |
Not clear |