| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Haowen Yin, Yuanyuan Liu, Hao Yue, Yingying Tian, Ping Dong, Changhu Xue, Yun-Tao Zhao, Zifang Zhao, Jingfeng Wan. DHA- and EPA-Enriched Phosphatidylcholine Suppress Human Lung Carcinoma 95D Cells Metastasis via Activating the Peroxisome Proliferator-Activated Receptor γ. Nutrients. vol 14. issue 21. 2022-11-11. PMID:36364935. |
furthermore, critical factors related to invasion, including matrix metallopeptidase 9 (mmp9), heparanase (hpa), and vascular endothelial growth factor (vegf), were drastically downregulated through the pparγ/nf-κb signaling pathway. |
2022-11-11 |
2023-08-14 |
human |
| Mingyue Jiang, You Sun, Kyung Son. Ginsenoside compound K suppresses tumor growth in the 22Rv1 xenograft model and inhibits androgenic responses via the transcriptional mechanism in human prostate cancer cells. The FEBS journal. 2022-11-09. PMID:36349420. |
gck downregulated epithelial-mesenchymal transition (emt) markers such as vimentin and matrix metalloproteinase 9 (mmp9), whereas e-cadherin was significantly increased in gck-stimulated lncap and 22rv1 cells. |
2022-11-09 |
2023-08-14 |
mouse |
| Longxiang Huang, Zhenni Wei, Xiaohui Wang, Chunlin Lan, Yihua Zhu, Qin Y. AZD6738 Decreases Intraocular Pressure and Inhibits Fibrotic Response in Trabecular Meshwork through CHK1/P53 Pathway. Biochemical pharmacology. 2022-11-08. PMID:36347274. |
further, we demonstrated that azd6738 reduces cell viability and migration, and inhibit the expression of fibrosis-related factors including fibronectin (fn), α-smooth muscle actin (α-sma), laminin subunit beta 1 (lamb1), matrix metallopeptidase (mmp) family including mmp2 and mmp9, collagen Ⅰ (col1), and collagen Ⅳ (col4), reduce gap junctions, altered cytoskeleton and nitric oxide production in tgf-β1-induced human trabecular meshwork cells (htmcs) through the chk1/p53 pathway, which were affected aqueous humor (ah) production and outflow pathway. |
2022-11-08 |
2023-08-14 |
mouse |
| Denes V Agoston, Jesse McCullough, Roxanne Aniceto, I-Hsuan Lin, Alaa Kamnaksh, Michael Eklund, Wallace M Graves, Cyrus Dunbar, James Engall, Eric B Schneider, Fabio Leonessa, Josh L Duckwort. Blood-Based Biomarkers of Repetitive, Subconcussive Blast Overpressure Exposure in the Training Environment: A Pilot Study. Neurotrauma reports. vol 3. issue 1. 2022-11-07. PMID:36337080. |
we detected elevated serum levels of glial fibrillary acidic protein, ubiquitin c-terminal hydrolase l1 (uch-l1), nicotinic alpha 7 subunit (chrna7), occludin (ocln), claudin-5 (cldn5), matrix metalloprotease 9 (mmp9), and intereukin-6 (il-6). |
2022-11-07 |
2023-08-14 |
Not clear |
| Li-Fang Liu, Yun Hu, Yi-Nuo Liu, De-Wen Shi, Chang Liu, Xin Da, Si-Hui Zhu, Qian-Yun Zhu, Ji-Qian Zhang, Guang-Hong X. Reactive oxygen species contribute to delirium-like behavior by activating CypA/MMP9 signaling and inducing blood-brain barrier impairment in aged mice following anesthesia and surgery. Frontiers in aging neuroscience. vol 14. 2022-11-07. PMID:36337710. |
cyclophilin a (cypa) is a specifically chemotactic leukocyte factor that can be secreted in response to ros, which activates matrix metalloproteinase 9 (mmp9) and mediates bbb breakdown. |
2022-11-07 |
2023-08-14 |
mouse |
| Jing Yu, Ling Guo, Si-Hai Zhang, Qun-Yin Zhu, Ru-Yi Chen, Boon Hui Wong, Guo-Hua Ding, Jie Che. Transcriptomic analysis of intermuscular bone development in barbel steed (Hemibarbus labeo). Comparative biochemistry and physiology. Part D, Genomics & proteomics. vol 44. 2022-11-07. PMID:36343604. |
in conclusion, we identified genes that may be related to ib development, such as kazal type serine peptidase inhibitor domain 1 (kazald1), extracellular matrix protein 1 (ecm1), tetranectin, bone morphogenetic protein 1 (bmp1), acid phosphatase 5 (acp5), collagen type xi alpha 1 chain (col11a1), matrix metallopeptidase 9 (mmp9), pannexin-3 (panx3), sp7 transcription factor (sp7), and c-x-c motif chemokine ligand 8 (cxcl8), by comparing the transcriptomes of epaxial muscle before and after ib ossification. |
2022-11-07 |
2023-08-14 |
Not clear |
| Hui-Seon Yun, Jong-Pyo Kim, Eun-Jung Kim, Byung-Gee Kim, Hee-Jin Jeon. A rapid ELISA for the detection of matrix metallopeptidase 9 using a recombinant Fab-type antibody. Biochemical and biophysical research communications. vol 636. issue Pt 1. 2022-11-05. PMID:36334443. |
matrix metalloproteinase 9 (mmp9) contributes to several aspects of inflammation and cancer pathology, including invasion, metastasis, and angiogenesis. |
2022-11-05 |
2023-08-14 |
Not clear |
| Hongkuan Han, Cheng Qian, Gangfan Zong, Huan Liu, Feihui Wang, Ruizhi Tao, Peng Cheng, Zhonghong Wei, Yang Zhao, Yin L. Systemic pharmacological verification of Salvia miltiorrhiza-Ginseng Chinese herb pair in inhibiting spontaneous breast cancer metastasis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 156. 2022-10-29. PMID:36308918. |
then, based on systematic pharmacology combined with gene expression omnibus (geo) database, potential targets of drugs were identified such as vascular endothelial growth factor a (vegfa), matrix metalloproteinase (mmp9), prostaglandin endoperoxide synthase2 (ptgs2), etc. |
2022-10-29 |
2023-08-14 |
Not clear |
| Flávia Mendonça, Amanda Mara Teles, Maria DO Desterro Soares Brandão Nascimento, Ana Paula Azevedo Dos Santos, Fernanda Ferreira Lopes, Anselmo Paiva, Haissa O Brito, Rui Gil DA Cost. Human Papillomavirus Modulates Matrix Metalloproteinases During Carcinogenesis: Clinical Significance and Role of Viral Oncoproteins. In vivo (Athens, Greece). vol 36. issue 6. 2022-10-29. PMID:36309355. |
matrix metalloproteinases such as mmp1, mmp9 and mmp13 have been associated with patient prognosis in hpv-induced cancers and play a major role in the degradation of the extracellular matrix, tumor invasion and metastasis. |
2022-10-29 |
2023-08-14 |
human |
| Briliant Adhi Prabowo, Carole Sousa, Susana Cardoso, Paulo Freitas, Elisabete Fernande. Labeling on a Chip of Cellular Fibronectin and Matrix Metallopeptidase-9 in Human Serum. Micromachines. vol 13. issue 10. 2022-10-27. PMID:36296077. |
in this study, the device performance was tested using commercial serum samples from healthy donors spiked with the following target proteins: cellular fibronectin (c-fn) and matrix metallopeptidase 9 (mmp9). |
2022-10-27 |
2023-08-14 |
human |
| Briliant Adhi Prabowo, Carole Sousa, Susana Cardoso, Paulo Freitas, Elisabete Fernande. Labeling on a Chip of Cellular Fibronectin and Matrix Metallopeptidase-9 in Human Serum. Micromachines. vol 13. issue 10. 2022-10-27. PMID:36296077. |
the spiked proteins of c-fn and mmp9 in the human serum-based matrix, were successfully labeled by the functionalized magnetic nanoparticles (mnps). |
2022-10-27 |
2023-08-14 |
human |
| Aitor Benedicto, Beatriz Arteta, Andrea Duranti, Daniel Alonso-Alconad. The Synthetic Cannabinoid URB447 Exerts Antitumor and Antimetastatic Effect in Melanoma and Colon Cancer. Pharmaceuticals (Basel, Switzerland). vol 15. issue 10. 2022-10-27. PMID:36297277. |
melanoma and crc cell migration was affected in a dose-dependent fashion as observed through scratch assay, whereas the secretion of matrix degrading proteins metalloprotease 2 (mmp2) and 9 (mmp9) in tumor cells did not significantly change. |
2022-10-27 |
2023-08-14 |
mouse |
| Majdolin Mohammed Eltayeb, Mohamed M Ali, Saeed M Omar, Nouh Saad Mohamed, Ishag Adam, Hamdan Z Hamda. Gene polymorphisms of cyclin-dependent kinase inhibitor and matrix metalloproteinase-9 in Sudanese patients with esophageal squamous cell carcinoma. Molecular genetics & genomic medicine. 2022-10-19. PMID:36259348. |
the polymorphisms of the cyclin-dependent kinase inhibitor (cdkn1a) gene and matrix metalloproteinase-9 (mmp9) gene may increase one's susceptibility to malignancies. |
2022-10-19 |
2023-08-14 |
Not clear |
| Rotem Kalev-Altman, Jerome Nicolas Janssen, Nir Ben-Haim, Tamar Levy, Astar Shitrit-Tovli, Joshua Milgram, Ron Shahar, Dalit Sela-Donenfeld, Efrat Monsonego-Orna. The gelatinases, matrix metalloproteinases 2 and 9, play individual roles in skeleton development. Matrix biology : journal of the International Society for Matrix Biology. 2022-10-19. PMID:36261075. |
the gelatinases, a subgroup of the matrix metalloproteinases (mmps) superfamily are composed of two members; mmp2 and mmp9. |
2022-10-19 |
2023-08-14 |
mouse |
| Hui Lu, Ryan Ashiqueali, Chin I Lin, Aashlesha Walchale, Victoria Clendaniel, Rudy Matheson, Marc Fisher, Eng H Lo, Magdy Selim, Amjad Shehada. Histone Deacetylase 3 Inhibition Decreases Cerebral Edema and Protects the Blood-Brain Barrier After Stroke. Molecular neurobiology. 2022-10-18. PMID:36258136. |
western blot for matrix metalloproteinase-9 (mmp9), mmp-9 zymography, and immunostaining for hdac3, gfap, iba-1, albumin, aquaporin-4, claudin-5, zo-1, and nf-kb were performed. |
2022-10-18 |
2023-08-14 |
rat |
| Jun-Chao Xue, Han-Yu Zhou, Liu-Shen-Yan Yu, Yan-Yan W. Effect of IL-8 on hepatocellular carcinoma-associated metastasis by targeting MMP9 in mice. Translational cancer research. vol 11. issue 7. 2022-10-17. PMID:36249885. |
interleukin-8 (il-8) and matrix metallopeptidase 9 (mmp9) are overexpressed in hepatocellular carcinoma (hcc), and both are related to tumor metastasis, but whether they regulate hcc metastasis is still unclear. |
2022-10-17 |
2023-08-14 |
mouse |
| Maryam Sadri, Ali-Akbar Delbandi, Nesa Rashidi, Gholam Ali Kardar, Reza Fala. Cobalt Chloride-induced Hypoxia Can Lead SKBR3 and HEK293T Cell Lines toward Epithelial-mesenchymal Transition. Iranian journal of allergy, asthma, and immunology. vol 21. issue 4. 2022-10-16. PMID:36243933. |
additionally, the expression of emt-associated markers including snail, e-cadherin, n-cadherin, and vimentin, as well as invasion-related genes including matrix metalloproteinase-2 (mmp2) and mmp9 was measured. |
2022-10-16 |
2023-08-14 |
Not clear |
| Lishan Lin, Yaling Yu, Kangping Liu, Yixin Jiang, Zhenlei Zho. Downregulation of miR-30b-5p Facilitates Chondrocyte Hypertrophy and Apoptosis via Targeting Runx2 in Steroid-Induced Osteonecrosis of the Femoral Head. International journal of molecular sciences. vol 23. issue 19. 2022-10-14. PMID:36232582. |
the nobly increased expression of matrix metallopeptidase 13 (mmp13) and type x collagen (col10a1) as runx2 downstream genes contributed to the hypertrophic differentiation of chondrocytes, and the efficiently upregulated level of matrix metallopeptidase 9 (mmp9) may trigger chondrocyte apoptosis with mps treatments. |
2022-10-14 |
2023-08-14 |
Not clear |
| Michael D Kim, Samuel Chung, John S Dennis, Makoto Yoshida, Carolina Aguiar, Sheyla P Aller, Eliana S Mendes, Andreas Schmid, Juan Sabater, Nathalie Baumlin, Matthias Salath. Vegetable glycerin e-cigarette aerosols cause airway inflammation and ion channel dysfunction. Frontiers in pharmacology. vol 13. 2022-10-13. PMID:36225570. |
markers of inflammation, including interleukin-6 (il6), interleukin-8 (il8) and matrix metalloproteinase-9 (mmp9) mrnas, as well as mmp-9 activity and mucin 5ac (muc5ac) expression levels, were also elevated in nasal samples from volunteers who vaped vg-containing e-liquids. |
2022-10-13 |
2023-08-14 |
human |
| Saverio Candido, Barbara Tomasello, Alessandro Lavoro, Luca Falzone, Giuseppe Gattuso, Angela Russo, Sabrina Paratore, James A McCubrey, Massimo Libr. Bioinformatic analysis of the Frontiers in cell and developmental biology. vol 10. 2022-10-10. PMID:36211450. |
bioinformatic analysis of the several features of cancer cells such as proliferation, invasion, metastatic spreading, and drug resistance are affected by their interaction with several tumor microenvironment (tme) components, including neutrophil gelatinase-associated lipocalin (ngal), solute carrier family 22 member 17 (slc22a17), and matrix metallopeptidase 9 (mmp9). |
2022-10-10 |
2023-08-14 |
Not clear |