| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qian Zhao, Juan Liu, Suhan Liu, Junhua Han, Yingxian Chen, Jianzhong Shen, Kui Zhu, Xiaowei M. Multipronged Micelles-Hydrogel for Targeted and Prolonged Drug Delivery in Chronic Wound Infections. ACS applied materials & interfaces. 2022-10-06. PMID:36201628. |
on the one hand, drugs could be released from micelles due to responsive disassembly by mmp9, a matrix metalloproteinase overexpressed in a chronic wound environment; on the other hand, crms showed specific targeting to egfr on epithelial cells and fibroblasts and therefore increased intracellular drug delivery. |
2022-10-06 |
2023-08-14 |
Not clear |
| Katharine Wolf, Safaa A Ibrahim, Sylvia Schneiderman, Valerie Riehl, Svetlana Dambaeva, Kenneth Beama. Conventional Natural Killer cells control vascular remodeling in the uterus during pregnancy by acidifying the extracellular matrix with a2V. Biology of reproduction. 2022-09-29. PMID:36173897. |
matrix metalloproteinase-9 (mmp9) is activated in acidic environments to promote uta remodeling. |
2022-09-29 |
2023-08-14 |
mouse |
| Katharine Wolf, Safaa A Ibrahim, Sylvia Schneiderman, Valerie Riehl, Svetlana Dambaeva, Kenneth Beama. Conventional Natural Killer cells control vascular remodeling in the uterus during pregnancy by acidifying the extracellular matrix with a2V. Biology of reproduction. 2022-09-29. PMID:36173897. |
we concluded that the role of cnk cells in the uterus is to acidify the extracellular matrix (ecm) using a2v, which activates mmp9 to degrade the ecm, release bound pro-angiogenic growth factors, and contribute to uta remodeling. |
2022-09-29 |
2023-08-14 |
mouse |
| Truong Huu Hoang, Misako Sato-Matsubara, Hideto Yuasa, Tsutomu Matsubara, Le Thi Thanh Thuy, Hiroko Ikenaga, Dong Minh Phuong, Ngo Vinh Hanh, Vu Ngoc Hieu, Dinh Viet Hoang, Hoang Hai, Yoshinori Okina, Masaru Enomoto, Akihiro Tamori, Atsuko Daikoku, Hayato Urushima, Kazuo Ikeda, Ninh Quoc Dat, Yutaka Yasui, Hiroji Shinkawa, Shoji Kubo, Ryota Yamagishi, Naoko Ohtani, Katsutoshi Yoshizato, Jordi Gracia-Sancho, Norifumi Kawad. Cancer cells produce liver metastasis via gap formation in sinusoidal endothelial cells through proinflammatory paracrine mechanisms. Science advances. vol 8. issue 39. 2022-09-28. PMID:36170363. |
tnf-α triggered depolymerization of f-actin and induced matrix metalloproteinase 9 (mmp9), intracellular adhesion molecule 1, and cxcl expression in lsecs. |
2022-09-28 |
2023-08-14 |
Not clear |
| Bin Lu, Min Cheng, Tao Wan. The Effect of lncRNA-PVT1 on Liver Cancer Rats by Regulating the Expression of MMP9. BioMed research international. vol 2022. 2022-09-27. PMID:36164442. |
the latest research claims that lncrna-pvt1 as a tumor gene participates in the generation and development of tumors by regulating matrix metalloproteinase mmp9. |
2022-09-27 |
2023-08-14 |
human |
| Ze-Yu Li, Er-Wei Hao, Rui Cao, Si Lin, Shu-Ying Chen, Xian-Ting Huang, Wan-Ru Xu, Xiao-Tao Hou, Jia-Gang Den. [Medication law and mechanism of traditional Chinese medicine in prevention and treatment of epidemic diseases: based on traditional Chinese medicine theory of cold pestilence]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 17. 2022-09-27. PMID:36164884. |
it was determined that the key targets were tumor necrosis factor(tnf), endothelial growth factor a(vegfa), serum creatinine(src), epidermal growth factor receptor(egfr), matrix metalloproteinase 9(mmp9), mitogen-activated protein kinase 14(mapk14), and prostaglandin-endoperoxide synthase 2(ptgs2), which were involved the mitogen-activated protein kinase(mapk) pathway, advanced glycation end-products(age)-receptor for age(rage) pathway, covid-19 pathway, and mtor pathway. |
2022-09-27 |
2023-08-14 |
Not clear |
| Christa Huuskonen, Mari Hämäläinen, Nooa Kivikangas, Timo Paavonen, Eeva Moilanen, Ari A Mennande. Early reversibility of histological changes after experimental acute cardiac volume-overload. American journal of cardiovascular disease. vol 12. issue 4. 2022-09-23. PMID:36147786. |
myocardial outcome was studied using histology and quantitative reverse-transcription polymerase chain reaction (qrt-pcr) analysis for hypoxia inducible factor 1alpha (hif1α), inducible nitric oxide synthase (inos), e-selectin, atrial natriuretic peptide (anp), brain natriuretic peptide (bnp), vascular endothelial growth factor alpha (vegfα), matrix metalloprotease 9 (mmp9), chitinase-3-like protein (ykl-40) and transforming growth factor beta (tgfβ). |
2022-09-23 |
2023-08-14 |
rat |
| Jianhua Guan, Bin Guan, Haixia Shang, Jun Peng, Hong Yang, Jiumao Li. Babao Dan inhibits lymphangiogenesis of gastric cancer in vitro and in vivo via lncRNA-ANRIL/VEGF-C/VEGFR-3 signaling axis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 154. 2022-09-04. PMID:36058147. |
in addition, wb assay found that bbd decreased the expression levels of vegf-c, vegfr-3, matrix metallopeptidase 2 (mmp2) and matrix metallopeptidase 9 (mmp9), and rt-qpcr assay found that the mrna expression levels of lncrna-anril, vegf-c, vegfr-3, mmp2, mmp9, cdk4, cyclin d1, and bcl-2 were down-regulated, and the expression of p21 and bax were increased. |
2022-09-04 |
2023-08-14 |
Not clear |
| Xiaoping Yang, Yuanyuan Yu, Yong Wang, Wen Jiang, Wenqing Jiang, Bin Yi. Genetic polymorphism of matrix metalloproteinase 9 and susceptibility to chronic obstructive pulmonary disease: A meta-analysis. Journal of medical biochemistry. vol 41. issue 3. 2022-08-31. PMID:36042908. |
to systematically analyze the influence of genetic polymorphisms of matrix metalloproteinase 9 (mmp9) on susceptibility to chronic obstructive pulmonary disease (copd). |
2022-08-31 |
2023-08-14 |
Not clear |
| Jiaqi Liu, Chao Guo, Yuqin Wang, Min Su, Wenjun Huang, Keng Po La. Preclinical insights into fucoidan as a nutraceutical compound against perfluorooctanoic acid-associated obesity Frontiers in nutrition. vol 9. 2022-08-29. PMID:36034923. |
our results identified ten targets of fucoidan, such as glucosylceramidase beta (gba), glutathione-disulfide reductase (gsr), melanocortin 4 receptor (mc4r), matrix metallopeptidase (mmp)2, mmp9, nuclear factor kappa b subunit 1 (nfkb1), rela proto-oncogene, nf-kb subunit (rela), nuclear receptor subfamily 1 group i member 2 (nr1i2), proliferation-activated receptor delta (ppard), and cellular retinoic acid binding protein 2 (crabp2). |
2022-08-29 |
2023-08-14 |
Not clear |
| Lin Cheng, Fan Yang, Xinlin Chen, Jiawei Kang, Jiafu Li, Yuanzhen Zhang, Juan Liu, Jin Li, Jianhong Ma, Jie Dua. Identification of Novel Compound Heterozygous Variants of Frontiers in genetics. vol 13. 2022-08-29. PMID:36035187. |
identification of novel compound heterozygous variants of matrix metalloproteinase 9 (mmp9) is an important member of the matrix metalloproteinase family and plays a key role in balancing extracellular matrix proteins. |
2022-08-29 |
2023-08-14 |
Not clear |
| Yihe Wang, Christine Y Chuang, Clare L Hawkins, Michael J Davie. Activation and Inhibition of Human Matrix Metalloproteinase-9 (MMP9) by HOCl, Myeloperoxidase and Chloramines. Antioxidants (Basel, Switzerland). vol 11. issue 8. 2022-08-26. PMID:36009335. |
activation and inhibition of human matrix metalloproteinase-9 (mmp9) by hocl, myeloperoxidase and chloramines. |
2022-08-26 |
2023-08-14 |
human |
| Yihe Wang, Christine Y Chuang, Clare L Hawkins, Michael J Davie. Activation and Inhibition of Human Matrix Metalloproteinase-9 (MMP9) by HOCl, Myeloperoxidase and Chloramines. Antioxidants (Basel, Switzerland). vol 11. issue 8. 2022-08-26. PMID:36009335. |
matrix metalloproteinase-9 (mmp9, gelatinase b) plays a key role in the degradation of extracellular-matrix (ecm) proteins in both normal physiology and multiple pathologies, including those linked with inflammation. |
2022-08-26 |
2023-08-14 |
human |
| Min Gong, Jianping Ji. Contribution of blood-brain barrier-related blood-borne factors for Alzheimer's disease vs. vascular dementia diagnosis: A pilot study. Frontiers in neuroscience. vol 16. 2022-08-25. PMID:36003963. |
we aimed to investigate the expression of blood-brain barrier (bbb)-related blood-borne factors of soluble low-density lipoprotein receptor-related protein 1 (slrp1), cyclophilin a (cypa), and matrix metalloproteinase 9 (mmp9) and its correlation with cognitive function between patients with ad and vad. |
2022-08-25 |
2023-08-14 |
Not clear |
| Anyu Xu, Jingchun Pei, Yunhong Yang, Baotong Hua, Jing Wan. IL-1β promotes A7r5 and HASMC migration and invasion via the p38-MAPK/Angpt-2 pathway. European journal of medical research. vol 27. issue 1. 2022-08-17. PMID:35978364. |
we pretreated a7r5 and hasmc with il-1β for 24 h, and measured the expression of il-1β, proliferating cell nuclear antigen (pcna), cyclin d1, matrix metalloproteinase 2 (mmp2) and matrix metalloproteinase 2 (mmp9) in the cells by western blotting. |
2022-08-17 |
2023-08-14 |
Not clear |
| Gang Deng, Tie-Jun Fu, Cui-Ping Li. Increased expression of Myosin X contributes to the metastasis in patients with laryngeal squamous cell carcinoma. Molecular genetics and genomics : MGG. 2022-08-11. PMID:35951144. |
myosin x augments the expression of cortactin, mmp2 and mmp9, which could upregulate the cell migration and the matrix degradation, and consequently reduce the expression of e-cadherin and β-catenin, thereby activating epithelial-mesenchymal transformation and promoting the metastasis of lscc. |
2022-08-11 |
2023-08-14 |
Not clear |
| Yingying Jiang, Wei Xu, Junzhen Ta. Circular RNA circVPRBP serves as a microRNA-106b-5p sponge to regulate proliferation and metastasis of cervical cancer cells via tripartite motif-containing protein 3. Anti-cancer drugs. 2022-08-10. PMID:35946546. |
protein levels of matrix metallopeptidase 2 (mmp2) and matrix mmp9, and trim3 were measured by western blot assay. |
2022-08-10 |
2023-08-14 |
human |
| Hossam El-Sheikh Ali, Kirsten Scoggin, Harutaka Murase, Jamie Norris, Bruno Menarim, Pouya Dini, Barry Bal. Transcriptomic and histochemical analysis reveal the complex regulatory networks in equine Chorioallantois during spontaneous term labor. Biology of reproduction. 2022-08-01. PMID:35913756. |
also, tl was associated with the upregulation of matrix metalloproteinase (mmp1, mmp2, mmp3, and mmp9) with subsequent extracellular matrix degradation and apoptosis, as reflected by upregulation of several apoptosis-related genes (atf3, atf4, fas, fos, and birc3). |
2022-08-01 |
2023-08-14 |
Not clear |
| Velmurugan Shanmugham, Ravi Subba. Capsanthin from Capsicum annum fruits exerts anti-glaucoma, antioxidant, anti-inflammatory activity, and corneal pro-inflammatory cytokine gene expression in a benzalkonium chloride-induced rat dry eye model. Journal of food biochemistry. 2022-07-27. PMID:35892258. |
capsanthin ameliorated in reducing oxidative stress by increasing serum antioxidant levels such as glutathione peroxidase (gpx), nitric oxide (no), and lactoferrin (ltf) and inhibiting matrix metalloproteinases 2 and 9 (mmp2 and mmp9) (p < .0001). |
2022-07-27 |
2023-08-14 |
rat |
| Velmurugan Shanmugham, Ravi Subba. Capsanthin from Capsicum annum fruits exerts anti-glaucoma, antioxidant, anti-inflammatory activity, and corneal pro-inflammatory cytokine gene expression in a benzalkonium chloride-induced rat dry eye model. Journal of food biochemistry. 2022-07-27. PMID:35892258. |
capsanthin treatment significantly inhibited the expression of inflammatory cytokines, tumor necrosis factor-alpha (tnf-α), interleukins (il-2, il-4, il-6), and pro-inflammatory mediator, matrix metalloproteinase-9 (mmp9). |
2022-07-27 |
2023-08-14 |
rat |