| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Katarzyna Augoff, Anita Hryniewicz-Jankowska, Renata Tabola, Kamilla Stac. MMP9: A Tough Target for Targeted Therapy for Cancer. Cancers. vol 14. issue 7. 2022-04-12. PMID:35406619. |
having the capability to proteolyze diverse structural and signaling proteins, matrix metalloproteinase 9 (mmp9), one of the best-studied secretory endopeptidases, has been identified as a crucial mediator of processes closely associated with tumorigenesis, such as the extracellular matrix reorganization, epithelial to mesenchymal transition, cell migration, new blood vessel formation, and immune response. |
2022-04-12 |
2023-08-13 |
Not clear |
| Furong Nie, Jingfeng Zhang, Mengyun Li, Xuanniu Chang, Haitao Duan, Haoyan Li, Jia Zhou, Yudan Ji, Liangxing Gu. Transcriptome analysis of thymic tissues from Chinese Partridge Shank chickens with or without Newcastle disease virus LaSota vaccine injection via high-throughput RNA sequencing. Bioengineered. vol 13. issue 4. 2022-04-11. PMID:35403571. |
both rna-seq and rt-qpcr outcomes showed that 10 transcripts (mstrg.22689.1, ensgalt00000065826, ensgalt00000059336, ensgalt00000060887, gga-mir-6575-5p, gga-mir-6631-5p, gga-mir-1727, paraoxonase 2 (pon2), mitogen-activated protein kinase 10, and cystic fibrosis transmembrane conductance regulator (cftr) were highly expressed, and 4 transcripts (mstrg.188121.10, gga-mir-6655-5p, gga-mir-6548-3p, and matrix metallopeptidase 9 (mmp9) were low expressed after ndv infection. |
2022-04-11 |
2023-08-13 |
Not clear |
| Caimei Wang, Yiyuan Wang, Congrong Liu, Xiaoyu Meng, Zhongxia Han. Kinetochore-associated protein 1 promotes the invasion and tumorigenicity of cervical cancer cells via matrix metalloproteinase-2 and matrix metalloproteinase-9. Bioengineered. vol 13. issue 4. 2022-04-07. PMID:35389773. |
protein expression levels of matrix metallopeptidase 2 (mmp2) and matrix metallopeptidase 9 (mmp9) were measured by western blotting. |
2022-04-07 |
2023-08-13 |
mouse |
| Yajing Wang, Fang Du, Zongyuan Xie, Junhao Lai, Yuanjie Li, Yongping Xu, Rui Ton. Circ_0005576 Exerts an Oncogenic Role in Cervical Cancer via miR-1305-Dependent Regulation of PAIP1. Reproductive sciences (Thousand Oaks, Calif.). 2022-04-05. PMID:35378711. |
the protein expression of cyclin d1, vimentin, and matrix metallopeptidase 9 (mmp9) was tested by western blot. |
2022-04-05 |
2023-08-13 |
mouse |
| Zhe Ge, Shan Wu, Zhengtang Qi, Shuzhe Din. Compared with High-intensity Interval Exercise, Moderate Intensity Constant Load Exercise is more effective in curbing the Growth and Metastasis of Lung Cancer. Journal of Cancer. vol 13. issue 5. 2022-04-04. PMID:35371324. |
in addition, the epithelial-mesenchymal transition (emt), which facilitates the tumor cell metastasis and invasion, is triggered by many stimuli, such as matrix metalloproteinases 2 (mmp2), mmp9, and transforming growth factor-β1 (tgf-β1). |
2022-04-04 |
2023-08-13 |
mouse |
| Agnes Schäfer, Lara Evers, Lara Meier, Uwe Schlomann, Miriam H A Bopp, Gian-Luca Dreizner, Olivia Lassmann, Aaron Ben Bacha, Andreea-Cristina Benescu, Mirza Pojskic, Christian Preußer, Elke Pogge von Strandmann, Barbara Carl, Christopher Nimsky, Jörg W Bartsc. The Metalloprotease-Disintegrin ADAM8 Alters the Tumor Suppressor miR-181a-5p Expression Profile in Glioblastoma Thereby Contributing to Its Aggressiveness. Frontiers in oncology. vol 12. 2022-04-04. PMID:35371977. |
in gbm, adam8 affects intracellular kinase signaling and increases expression levels of osteopontin/spp1 and matrix metalloproteinase 9 (mmp9) by an unknown mechanism. |
2022-04-04 |
2023-08-13 |
Not clear |
| Kun Zhao, Yong Li, Zihao Zhou, Yukang Mao, Xiaoguang Wu, Dongxu Hua, Yonghong Yong, Peng L. Ginkgolide A alleviates cardiac remodeling in mice with myocardial infarction via binding to matrix metalloproteinase-9 to attenuate inflammation. European journal of pharmacology. 2022-04-03. PMID:35367419. |
this study aims to explore whether ginkgolide a (ga) could improve cardiac dysfunction of mi mice, and whether it could alleviate cardiac remodeling via binding to matrix metalloproteinase-9 (mmp9) to attenuate inflammation. |
2022-04-03 |
2023-08-13 |
mouse |
| Min Zhang, Xia Meng, Yuesong Pan, Yilong Wang, Xingquan Zhao, Liping Liu, Jiejie Li, Hongyi Yan, Xiangrong Liu, Hui Zhang, Lijuan Pang, Yongjun Wan. Predictive values of Baseline MMP9 Levels in Peripheral Blood on 3-Month outcomes of high-risk patients with minor stroke or TIA. European journal of neurology. 2022-03-31. PMID:35357766. |
to explore the relationship between baseline levels of matrix metalloproteinase 9 (mmp9) in peripheral blood and the outcomes in patients with acute minor stroke and transient ischemic attack (tia). |
2022-03-31 |
2023-08-13 |
Not clear |
| Ben A Strickland, Giuseppe Barisano, Aidin Abedi, Mark S Shiroishi, Steven Cen, Benjamin Emanuel, Sebina Bulic, May Kim-Tenser, Peggy Nguyen, Steven L Giannotta, William Mack, Jonathan Russi. Minocycline decreases blood-brain barrier permeability following aneurysmal subarachnoid hemorrhage: a randomized, double-blind, controlled trial. Journal of neurosurgery. 2022-03-29. PMID:35349976. |
elevations in serum levels of matrix metalloprotease 9 (mmp9), a bbb structural protein, have been implicated in the pathogenesis of vasospasm onset. |
2022-03-29 |
2023-08-13 |
Not clear |
| Xiting Liu, Ze Chen, Yuqiang Wu, Feng Gu, Dong Yan, Lei Yang, Qin Ma, Caihong F. Circ_0078767 Inhibits the Progression of Non-Small-Cell Lung Cancer by Regulating the GPX3 Expression by Adsorbing miR-665. International journal of genomics. vol 2022. 2022-03-28. PMID:35340708. |
western blot examined the protein levels of hexokinase-2 (hk2), matrix metalloproteinase-9 (mmp9), and gpx3 cells. |
2022-03-28 |
2023-08-13 |
Not clear |
| Yanyan Chi, Feng Wang, Yana Zhang, Zhengzheng Shan, Weili Tao, Yujin Lian, Dao Xin, Qingxia Fan, Yan Su. Apatinib inhibits tumour progression and promotes antitumour efficacy of cytotoxic drugs in oesophageal squamous cell carcinoma. Journal of cellular and molecular medicine. 2022-03-22. PMID:35315581. |
western blot analysis showed that apatinib significantly increased vimentin protein levels, decreased bcl2, matrix metalloproteinase 9 (mmp9), e-cadherin, p-akt and p-mtor protein levels in escc cells. |
2022-03-22 |
2023-08-13 |
Not clear |
| b' Mustafa Onur Y\\xc4\\xb1ld\\xc4\\xb1z, Hamit \\xc3\\x87elik, Cuneyt Caglayan, Ayd\\xc4\\xb1n Gen\\xc3\\xa7, Tuba Do\\xc4\\x9fan, Emine Sat\\xc4\\xb1c\\xc4\\xb. Neuroprotective effects of carvacrol against cadmium-induced neurotoxicity in rats: role of oxidative stress, inflammation and apoptosis. Metabolic brain disease. 2022-03-22. PMID:35316447.' |
carvacrol also decreased the mrna expression of matrix metalloproteinases (mmp9 and mmp13), as well as 8-hydroxy-2'-deoxyguanosine (8 - ohdg) level, a marker of oxidative dna damage. |
2022-03-22 |
2023-08-13 |
rat |
| b' Milica Vukoti\\xc4\\x87, Sun\\xc4\\x8dica Kapor, Teodora Dragojevi\\xc4\\x87, Dragoslava \\xc4\\x90iki\\xc4\\x87, Olivera Mitrovi\\xc4\\x87 Ajti\\xc4\\x87, Milo\\xc5\\xa1 Dikli\\xc4\\x87, Tijana Suboti\\xc4\\x8dki, Emilija \\xc5\\xbdivkovi\\xc4\\x87, Bojana Beleslin \\xc4\\x8coki\\xc4\\x87, Aleksandar Vojvodi\\xc4\\x87, Juan F Santib\\xc3\\xa1\\xc3\\xb1ez, Mirjana Goti\\xc4\\x87, Vladan P \\xc4\\x8coki\\xc4\\x8. Inhibition of proinflammatory signaling impairs fibrosis of bone marrow mesenchymal stromal cells in myeloproliferative neoplasms. Experimental & molecular medicine. 2022-03-15. PMID:35288649.' |
these cells display a dysregulated extracellular matrix with increased fn1 production and secretion of profibrotic mmp9 compared to healthy donor cells. |
2022-03-15 |
2023-08-13 |
Not clear |
| Sachiko Murase, Sarah E Robertson, Crystal L Lantz, Ji Liu, Daniel E Winkowski, Elizabeth M Quinla. Chronic Monocular Deprivation Reveals MMP9-Dependent and -Independent Aspects of Murine Visual System Plasticity. International journal of molecular sciences. vol 23. issue 5. 2022-03-10. PMID:35269580. |
the deletion of matrix metalloproteinase mmp9 is combined here with chronic monocular deprivation (cmd) to identify the contributions of this proteinase to plasticity in the visual system. |
2022-03-10 |
2023-08-13 |
mouse |
| Odelia Cooper, Vivien Bonert, Adam N Mamelak, Serguei Bannykh, Shlomo Melme. Dural Invasion as a Marker of Aggressive Pituitary Adenomas. Neurosurgery. 2022-03-09. PMID:35262532. |
dural invasion and invasion-associated proteins, including matrix metalloproteinase-9 (mmp9) and cofilin, have been proposed to predict aggressive behavior and recurrence, but findings to date have been inconsistent. |
2022-03-09 |
2023-08-13 |
Not clear |
| Ryuta Suzuki, Noriaki Kamio, Kozue Sugimoto, Shuichiro Maruoka, Yasuhiro Gon, Tadayoshi Kaneko, Yoshiyuki Yonehara, Kenichi Ima. Periodontopathic Bacterium In vivo (Athens, Greece). vol 36. issue 2. 2022-03-04. PMID:35241518. |
matrix metalloproteinase-9 (mmp9) plays important roles in pneumonia, chronic obstructive pulmonary disease, and asthma; therefore, we assessed the effects of fusobacterium nucleatum on mmp9 expression in mouse lung and a549 human alveolar epithelial cells. |
2022-03-04 |
2023-08-13 |
mouse |
| Yinglei Liu, Yang Cao, Haili Kai, Yuwen Han, Menghui Huang, Liusijie Gao, Haifeng Qia. Polyphyllin E inhibits proliferation, migration and invasion of ovarian cancer cells by down-regulating the AKT/NF-κB pathway. Biological & pharmaceutical bulletin. 2022-02-21. PMID:35185080. |
the mechanistic assessment revealed ppe-mediated matrix metalloproteinases, i.e., mmp2 and mmp9, inhibition via the akt/ nuclear factor kappa b (akt/nf-κb) signaling pathway. |
2022-02-21 |
2023-08-13 |
Not clear |
| Emile Verhulst, Delphine Garnier, Ingrid De Meester, Brigitte Bauvoi. Validating Cell Surface Proteases as Drug Targets for Cancer Therapy: What Do We Know, and Where Do We Go? Cancers. vol 14. issue 3. 2022-02-15. PMID:35158891. |
several members, most notably dipeptidyl peptidase 4 (dpp4/cd26) and its related family member fibroblast activation protein (fap), aminopeptidase n (apn/cd13), a disintegrin and metalloprotease 17 (adam17/tace), and matrix metalloproteinases (mmps) mmp2 and mmp9, are often overexpressed in cancers and have been associated with tumour dysfunction. |
2022-02-15 |
2023-08-13 |
human |
| Chia-Yu Hung, Chih-Han Chang, Tzu-Jung Lin, Hsin-Hui Yi, Nian-Zhen Tsai, Yu-Ru Chen, Yng-Tay Che. AQP4 Attenuated TRAF6/NFκB Activation in Acrylamide-Induced Neurotoxicity. Molecules (Basel, Switzerland). vol 27. issue 3. 2022-02-15. PMID:35164330. |
matrix metalloproteinase (mmp9) expression was higher in the acr-treated group than in the control group. |
2022-02-15 |
2023-08-13 |
rat |
| Woobeen Jo, Min Kim, Jiyoung Oh, Chu-Sook Kim, Chanho Park, Sora Yoon, Changhu Lee, Sahee Kim, Dougu Nam, Jiyoung Par. MicroRNA-29 Ameliorates Fibro-Inflammation and Insulin Resistance in HIF1α-Deficient Obese Adipose Tissue by Inhibiting Endotrophin Generation. Diabetes. 2022-02-15. PMID:35167651. |
herein, we identified that several endotrophin-containing peptides (pre-endotrophins) were generated from the col6a3 chain in a stepwise manner for the efficient production of mature endotrophin, partly through the action of hypoxia-induced matrix metalloproteinases (mmps), including mmp2, mmp9, and mmp16. |
2022-02-15 |
2023-08-13 |
mouse |