| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Huajie Mao, Bin Han, Hao Li, Yiqing Tao, Weigang W. FABP4 knockdown suppresses inflammation, apoptosis and extracellular matrix degradation in IL-1β-induced chondrocytes by activating PPARγ to regulate the NF-κB signaling pathway. Molecular medicine reports. vol 24. issue 6. 2021-10-26. PMID:34651666. |
following fabp4 knockdown, the expression of matrix metalloproteinases (mmp3, mmp9 and mmp13) of il‑1β‑induced atdc5 cells was reduced, and the expression of gag was promoted. |
2021-10-26 |
2023-08-13 |
Not clear |
| Termeh Shakery, Fatemeh Safar. Down regulation of Pinkbar/pAKT and MMP2/MMP9 expression in MDA-MB-231 breast cancer cells as potential targets in cancer therapy by hAMSCs secretome. Cells, tissues, organs. 2021-10-25. PMID:34695828. |
in present study, we explored the therapeutic effects of human amniotic mesenchymal stromal cells (hamscs) through pinkbar (planar intestinal-and kidney-specific bar domain protein), pakt, and matrix metalloproteinases including mmp2, mmp9 on mda-mb-231 breast cancer cells. |
2021-10-25 |
2023-08-13 |
human |
| Mingyang Li, Licheng Cai, Xingyuan Wang, Yipeng Yu, Wengang Jian, Guochang Bao, Zhiming Gao, Junsheng Guo, Jian Zhang, Chunsheng Li, Cheng Zhan. RHBDD1 promotes proliferation, migration, invasion and EMT in renal cell carcinoma via the EGFR/AKT signaling pathway. Molecular medicine reports. vol 24. issue 6. 2021-10-22. PMID:34581421. |
in addition, key proteins related to migration, invasion and epithelial‑mesenchymal transition (emt), such as matrix metalloproteinase (mmp)2, mmp9, mmp13, e‑cadherin, n‑cadherin, vimentin and slug, were analyzed using western blotting. |
2021-10-22 |
2023-08-13 |
human |
| J J Provost, D Rastedt, J Canine, T Ngyuen, A Haak, C Kutz, N Berthelsen, A Slusser, K Anderson, G Dorsam, M A Waller. Urokinase plasminogen activator receptor induced non-small cell lung cancer invasion and metastasis requires NHE1 transporter expression and transport activity. Cellular oncology (Dordrecht). vol 35. issue 2. 2021-10-21. PMID:22290545. |
comparing upa and atf signaling in h460 cells, we found that both upa and atf increased stress fiber formation approximately 2 fold, while upa increased matrix metalloproteinase 9 (mmp9) activity 5.44 fold compared to 2.81 fold for atf. |
2021-10-21 |
2023-08-12 |
mouse |
| Jianwu Hu, Caiyun Chen, Yuan Su, Jiao DU, Xin Qian, Yang Ji. Vascular endothelial growth factor promotes the expression of cyclooxygenase 2 and matrix metalloproteinases in Lewis lung carcinoma cells. Experimental and therapeutic medicine. vol 4. issue 6. 2021-10-21. PMID:23226772. |
cyclooxygenase (cox)-2, matrix metalloproteinase (mmp)2, mmp9 and wild-type (wt) p53 has been found to regulate the production of vegf. |
2021-10-21 |
2023-08-12 |
Not clear |
| Marta Lydka, Barbara Bilinska, C Yan Cheng, Dolores D Mru. Tumor necrosis factor α-mediated restructuring of the Sertoli cell barrier in vitro involves matrix metalloprotease 9 (MMP9), membrane-bound intercellular adhesion molecule-1 (ICAM-1) and the actin cytoskeleton. Spermatogenesis. vol 2. issue 4. 2021-10-21. PMID:23248771. |
tumor necrosis factor α-mediated restructuring of the sertoli cell barrier in vitro involves matrix metalloprotease 9 (mmp9), membrane-bound intercellular adhesion molecule-1 (icam-1) and the actin cytoskeleton. |
2021-10-21 |
2023-08-12 |
human |
| Jianting Gan, Ping Li, Zhengdong Wang, Jian Chen, Xiangwen Liang, Ming Liu, Wenchao Xie, Ruixing Yin, Feng Huan. Rosuvastatin suppresses platelet-derived growth factor-BB-induced vascular smooth muscle cell proliferation and migration via the MAPK signaling pathway. Experimental and therapeutic medicine. vol 6. issue 4. 2021-10-21. PMID:24137286. |
moreover, we also showed that rosuvastatin significantly suppressed pdgf-bb-induced vsmc migration, which may be a result of its inhibitory effect on the protein expression of matrix metalloproteinase-2 (mmp2) and mmp9. |
2021-10-21 |
2023-08-12 |
Not clear |
| Miao Mo, Fenghua Peng, Lu Wang, Longkai Peng, Gongbin Lan, Shaojie Y. Roles of mitochondrial transcription factor A and microRNA-590-3p in the development of bladder cancer. Oncology letters. vol 6. issue 2. 2021-10-21. PMID:24137381. |
furthermore, cell proliferation- and migration-related genes, including phosphoinositide-3-kinase (pi3k), akt, matrix metalloproteinase (mmp)-2 and mmp9, were significantly downregulated in the mirna-590-3p-overex-pressing 5637 cells, but upregulated in the tfam-overexpressing cells. |
2021-10-21 |
2023-08-12 |
Not clear |
| Barun Poudel, DO-Kuk Kim, Hyeon-Hui Ki, Young-Bae Kwon, Young-Mi Lee, Dae-Ki Ki. Downregulation of ERK signaling impairs U2OS osteosarcoma cell migration in collagen matrix by suppressing MMP9 production. Oncology letters. vol 7. issue 1. 2021-10-21. PMID:24348851. |
downregulation of erk signaling impairs u2os osteosarcoma cell migration in collagen matrix by suppressing mmp9 production. |
2021-10-21 |
2023-08-12 |
human |
| Barun Poudel, DO-Kuk Kim, Hyeon-Hui Ki, Young-Bae Kwon, Young-Mi Lee, Dae-Ki Ki. Downregulation of ERK signaling impairs U2OS osteosarcoma cell migration in collagen matrix by suppressing MMP9 production. Oncology letters. vol 7. issue 1. 2021-10-21. PMID:24348851. |
furthermore, enhanced gene and protein expression of matrix metalloproteinase 9 (mmp9), but not mmp2, was observed to be involved in the enhanced migratory phenotype of the u20s cells in the collagen-coated plates. |
2021-10-21 |
2023-08-12 |
human |
| Barun Poudel, DO-Kuk Kim, Hyeon-Hui Ki, Young-Bae Kwon, Young-Mi Lee, Dae-Ki Ki. Downregulation of ERK signaling impairs U2OS osteosarcoma cell migration in collagen matrix by suppressing MMP9 production. Oncology letters. vol 7. issue 1. 2021-10-21. PMID:24348851. |
collectively, the data demonstrate that erk signaling is important for the migration of u2os cells through the extracellular matrix (ecm), which is comprised mostly of collagen, by enhancing mmp9 production. |
2021-10-21 |
2023-08-12 |
human |
| Hui-Ping Ma, Wei Li, Xiao-Min Li. Matrix metalloproteinase 9 is involved in airway inflammation in cough variant asthma. Experimental and therapeutic medicine. vol 8. issue 4. 2021-10-21. PMID:25187823. |
previous studies have revealed the role of matrix metalloproteinase 9 (mmp9) in asthma and chronic obstructive pulmonary disease (copd). |
2021-10-21 |
2023-08-13 |
Not clear |
| Sheng-Yu Lee, Tzu-Yun Wang, Ru-Band Lu, Liang-Jen Wang, Sung-Chou Li, Chi-Ying Tu, Cheng-Ho Chang, Yung-Chih Chiang, Kuo-Wang Tsa. Identification of potential plasma protein biomarkers for bipolar II disorder: a preliminary/exploratory study. Scientific reports. vol 11. issue 1. 2021-10-21. PMID:33947873. |
we used isobaric tags for relative and absolute quantification technology to identify five upregulated candidate proteins [matrix metallopeptidase 9 (mmp9), phenylalanyl-trna synthetase subunit beta (farsb), peroxiredoxin 2 (prdx2), carbonic anhydrase 1 (ca-1), and proprotein convertase subtilisin/kexin type 9 (pcsk9)] for the diagnosis of bd-ii. |
2021-10-21 |
2023-08-13 |
human |
| Yongjuan Gu, Zhigang Zho. Berberine inhibits the proliferation, invasion and migration of endometrial stromal cells by downregulating miR‑429. Molecular medicine reports. vol 23. issue 6. 2021-10-18. PMID:33846796. |
wound healing and transwell assays were performed to detect cell migration and invasion, and western blotting was used to detect the expression of the migration‑ and invasion‑related proteins, including matrix metalloproteinase (mmp)2, mmp4 and mmp9. |
2021-10-18 |
2023-08-13 |
human |
| Tao Yao, Lei Zhang, Ye Fu, Lina Yao, Chengjie Zhou, Guozhong Che. Saikosaponin-d Alleviates Renal Inflammation and Cell Apoptosis in a Mouse Model of Sepsis via TCF7/FOSL1/Matrix Metalloproteinase 9 Inhibition. Molecular and cellular biology. vol 41. issue 10. 2021-10-12. PMID:34309413. |
dual luciferase reporter gene and chromatin immunoprecipitation (chip) assays were used to explore the interactions between tcf7, fosl1, and matrix metalloproteinase 9 (mmp9). |
2021-10-12 |
2023-08-13 |
mouse |
| Haiqiao Xu, Shibang Lin, Haizhou Huan. Involvement of increased expression of chemokine C-C motif chemokine 22 (CCL22)/CC chemokine receptor 4 (CCR4) in the inflammatory injury and cartilage degradation of chondrocytes. Cytotechnology. vol 73. issue 5. 2021-10-12. PMID:34629747. |
the expressions of ccl22, ccr4, matrix metallopeptidase (mmp) 3, mmp9, mmp13, (a disintegrin and metalloproteinase with thrombospondin-like motifs) adamts-4, collagen ii and inflammatory cytokines were measured using quantitative reverse transcription pcr (rt-qpcr) and western blot. |
2021-10-12 |
2023-08-13 |
Not clear |
| Charis Ringland, Jonas Elias Schweig, Maxwell Eisenbaum, Daniel Paris, Ghania Ait-Ghezala, Michael Mullan, Fiona Crawford, Laila Abdullah, Corbin Bachmeie. MMP9 modulation improves specific neurobehavioral deficits in a mouse model of Alzheimer's disease. BMC neuroscience. vol 22. issue 1. 2021-10-11. PMID:34034683. |
matrix metallopeptidase 9 (mmp9) has been implicated in a variety of neurological disorders, including alzheimer's disease (ad), where mmp9 levels are elevated in the brain and cerebrovasculature. |
2021-10-11 |
2023-08-13 |
mouse |
| Ourlad Alzeus G Tantengco, Lauren S Richardson, Joy Vink, Talar Kechichian, Paul Mark B Medina, Richard B Pyles, Ramkumar Meno. Progesterone alters human cervical epithelial and stromal cell transition and migration: Implications in cervical remodeling during pregnancy and parturition. Molecular and cellular endocrinology. vol 529. 2021-10-08. PMID:33823217. |
inflammatory cytokines (interleukin-6 [il-6], tumor necrosis factor α [tnfα]) and matrix metallopeptidase 9 (mmp9) were measured by elisa. |
2021-10-08 |
2023-08-13 |
human |
| Jennifer Maries Go Yap, Takashi Ueda, Norihisa Takeda, Kensuke Fukumitsu, Satoshi Fukuda, Takehiro Uemura, Tomoko Tajiri, Hirotsugu Ohkubo, Ken Maeno, Yutaka Ito, Yoshihiro Kanemitsu, Akio Niim. An inflammatory stimulus sensitizes TRPA1 channel to increase cytokine release in human lung fibroblasts. Cytokine. vol 129. 2021-10-07. PMID:32050145. |
lastly, trpa1 activation was not only involved in increased il-8 cytokine release, but also in upregulating gene expression of matrix metalloprotease 9 (mmp9) in the human lung fibroblasts treated with tnf-α together, these results indicate that presence of inflammatory mediators such as tnf-α could upregulate the non-neuronal expression of trpa1 on fibroblasts which may aggravate further the release of inflammatory cytokines observed in human airway diseases. |
2021-10-07 |
2023-08-13 |
human |
| Hiroyuki Kato, Aya Naiki-Ito, Takehiro Yamada, Shugo Suzuki, Yoriko Yamashita, Shingo Inaguma, Naoto Kondo, Yumi Wanifuchi-Endo, Tatsuya Toyama, Satoru Takahash. The standard form of CD44 as a marker for invasion of encapsulated papillary carcinoma of the breast. Pathology international. vol 70. issue 11. 2021-10-07. PMID:32783311. |
we immunohistochemically assessed the expression of hormone receptors, matrix metalloproteinase (mmp) 2 and mmp9, vascular endothelial growth factor (vegf), cd31, and d2-40, markers of tumor-associated macrophages (cd163, cd206), ki-67 and stem cell markers (cd44 and cd24). |
2021-10-07 |
2023-08-13 |
Not clear |