| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| b' Marija \\xc4\\x90or\\xc4\\x91i\\xc4\\x87 Crnogorac, Ivana Z Mati\\xc4\\x87, Ana Damjanovi\\xc4\\x87, Nenad Jankovi\\xc4\\x87, Ana Krivoku\\xc4\\x87a, Tatjana Stanojkovi\\xc4\\x8. 3D HeLa spheroids as a model for investigating the anticancer activity of Biginelli-hybrids. Chemico-biological interactions. vol 345. 2021-08-02. PMID:34161784.' |
the invasion potential of treated hela cells in spheroids was monitored by imaging of spheroids embedded in a matrix made of matrigel and collagen and by determination of mmp2, mmp9, and vegf gene expression levels. |
2021-08-02 |
2023-08-13 |
Not clear |
| Yuming Xu, Erhui Jiang, Zhe Shao, Zhengjun Shan. LncRNA FENDRR in Carcinoma-Associated Fibroblasts Regulates the Angiogenesis of Oral Squamous Cell Carcinoma Through the PI3K/AKT Pathway. Frontiers in oncology. vol 11. 2021-07-31. PMID:34327132. |
further experiments confirmed that the downregulation of fendrr can activate the pi3k/akt pathway in nfs and enhances the expression of matrix metalloproteinase 9 (mmp9). |
2021-07-31 |
2023-08-13 |
human |
| Hossam El-Sheikh Ali, Kirsten E Scoggin, Rebecca Ruby, Alan Loynachan, Yatta Boakari, Claudia Fernandes, Pouya Dini, Carleigh Elizabeth Fedorka, Shavahn C Loux, Alejandro Esteller-Vico, Barry A Bal. Equine cervical remodeling during placentitis and the prepartum period: a transcriptomic approach. Reproduction (Cambridge, England). vol 161. issue 6. 2021-07-30. PMID:33780349. |
these pathways were accompanied by upregulation of several proteases, including matrix metalloproteinases (mmp1, mmp2, and mmp9), cathepsins (ctsb, ctsc, and ctsd) and a disintegrin and metalloproteinase with thrombospondin type 1 motifs (adamts1, adamts4, and adamts5), which are crucial for degradation of cervical collagens during remodeling. |
2021-07-30 |
2023-08-13 |
Not clear |
| Rong Hu, Libo Chen, Xiaolong Chen, Zhong Xie, Chao Xia, Yong Che. Aloperine improves osteoporosis in ovariectomized mice by inhibiting RANKL-induced NF-κB, ERK and JNK approaches. International immunopharmacology. vol 97. 2021-07-30. PMID:33945918. |
in addition, it is found that aloperine can inhibit the expression of osteoclast specific marker genes, including nuclear factor of activated t cells cytoplasmic 1 (nfatc1), tartrate resistant acid phosphatase (tracp), matrix metallopeptidase 9 (mmp9), cathepsin k (ctsk), v-atpase d2 and calcitonin receptor. |
2021-07-30 |
2023-08-13 |
mouse |
| Yan Dai, Tian-He Li, Xin He, Song-Biao Yan, Yan Gao, Yi Che. The Effect and Mechanism of Asymmetric Dimethylarginine Regulating Trophoblastic Autophagy on Fetal Growth Restriction. Reproductive sciences (Thousand Oaks, Calif.). vol 28. issue 7. 2021-07-28. PMID:33428125. |
and the expression of matrix metalloproteinase 9 (mmp9) was decreased in the placenta of patients with fgr. |
2021-07-28 |
2023-08-13 |
human |
| Yiheng Yang, Hongli Pan, Jie Chen, Zhonghua Zhang, Minna Liang, Xunqiang Fen. CircKIF2A contributes to cell proliferation, migration, invasion and glycolysis in human neuroblastoma by regulating miR-129-5p/PLK4 axis. Molecular and cellular biochemistry. vol 476. issue 6. 2021-07-28. PMID:33630225. |
western blot assay was performed to examine the protein levels of matrix metalloproteinase 2 (mmp2), mmp9 and plk4. |
2021-07-28 |
2023-08-13 |
human |
| Mikako Saito, Ryota Kishi, Tomoko Sasai, Tomohiro Hatakenaka, Nahoko Matsuki, Seiya Minagaw. Effect of Nanog overexpression on the metastatic potential of a mouse melanoma cell line B16-BL6. Molecular and cellular biochemistry. vol 476. issue 7. 2021-07-27. PMID:33665763. |
in vitro tests revealed the enhancement of cell proliferation, wound healing activity, and matrix metalloproteinase 9 (mmp9) activity. |
2021-07-27 |
2023-08-13 |
mouse |
| Qi He, Nian Liu, Feng Hu, Quan Shi, Xianming Pi, Hongxiang Chen, Jiawen Li, Bo Zhan. Circ_0061012 contributes to IL-22-induced proliferation, migration and invasion in keratinocytes through miR-194-5p/GAB1 axis in psoriasis. Bioscience reports. vol 41. issue 1. 2021-07-21. PMID:33393621. |
western blot assay was used to measure the protein levels of ki67, matrix metallopeptidase 9 (mmp9) and gab1. |
2021-07-21 |
2023-08-13 |
human |
| Mittal Jasoliya, Heather Bowling, Ignacio Cortina Petrasic, Blythe Durbin-Johnson, Eric Klann, Aditi Bhattacharya, Randi Hagerman, Flora Tasson. Blood-Based Biomarkers Predictive of Metformin Target Engagement in Fragile X Syndrome. Brain sciences. vol 10. issue 6. 2021-07-20. PMID:32531912. |
we specifically tested a triplex protein array comprising of hexokinase 1 (hk1), ras (all isoforms), and matrix metalloproteinase 9 (mmp9) that we previously demonstrated were dysregulated in the fxs mouse model and in blood samples from patient with fxs. |
2021-07-20 |
2023-08-13 |
mouse |
| Wenyi Pang, Zhu Zhang, Yunxia Zhang, Meng Zhang, Ran Miao, Yuanhua Yang, Wanmu Xie, Jun Wan, Zhenguo Zhai, Chen Wan. Extracellular matrix collagen biomarkers levels in patients with chronic thromboembolic pulmonary hypertension. Journal of thrombosis and thrombolysis. vol 52. issue 1. 2021-07-16. PMID:33175289. |
serum levels of procollagen iii n-terminal peptide (piiinp), carboxyterminal propeptide of type i procollagen (picp), matrix metalloproteinases (mmp2), mmp9, and tissue inhibitor of metalloproteinases 1(timp1) were measured by elisa. |
2021-07-16 |
2023-08-13 |
Not clear |
| Chengwei Wu, Xianghai Wang, Xingwei Wu, Xingwu Che. Ectodermal‑neural cortex 1 affects the biological function of lung cancer through the MAPK pathway. International journal of molecular medicine. vol 47. issue 5. 2021-07-16. PMID:33693958. |
the knockdown of enc1 significantly downregulated the levels of matrix metalloproteinase (mmp)2, mmp9, n‑cadherin, p‑c‑jun n‑terminal kinase (jnk), p‑extracellular signal‑regulated kinase (erk) and p‑p38. |
2021-07-16 |
2023-08-13 |
mouse |
| Hossam El-Sheikh Ali, Pouya Dini, Kirsten Scoggin, Shavahn Loux, Carleigh Fedorka, Yatta Boakari, Jamie Norris, Alejandro Esteller-Vico, Theodore Kalbfleisch, Barry Bal. Transcriptomic analysis of equine placenta reveals key regulators and pathways involved in ascending placentitis†. Biology of reproduction. vol 104. issue 3. 2021-07-15. PMID:33345276. |
placentitis was associated with the upregulation of matrix metalloproteinase (mmp1, mmp2, and mmp9) and apoptosis-related genes such as caspases (casp3, casp4, and casp7) in ca. |
2021-07-15 |
2023-08-13 |
Not clear |
| Namjoon Cho, Sung-Gwon Lee, Jong Ok Kim, Yong-An Kim, Eun-Mi Kim, Chungoo Park, Jong-Hun Ji, Kee K Ki. Identification of Differentially Expressed Genes Associated with Extracellular Matrix Degradation and Inflammatory Regulation in Calcific Tendinopathy Using RNA Sequencing. Calcified tissue international. vol 107. issue 5. 2021-07-14. PMID:32776213. |
further, matrix metalloproteinase 9 (mmp9) and matrix metalloproteinase 13 (mmp13), two of the enzymes associated with ecm degradation, were found to be highly upregulated 25.85- and 19.40-fold, respectively, in the calcific tendon tissues compared to the adjacent normal tendon tissues. |
2021-07-14 |
2023-08-13 |
Not clear |
| José Manuel Benitez-Del-Castillo, Javier Soria, Arantxa Acera, Ana María Muñoz, Sandra Rodríguez, Tatiana Suáre. Quantification of a panel for dry-eye protein biomarkers in tears: A comparative pilot study using standard ELISA and customized microarrays. Molecular vision. vol 27. 2021-07-13. PMID:34012227. |
this paper examines the tear concentration of cystatin s (cst4), calcyclin (s100a6), calgranulin a (s100a8), and matrix metalloproteinase 9 (mmp9), and the correlation between biomarker expression, clinical parameters, and disease severity in patients suffering from dry eye (de). |
2021-07-13 |
2023-08-13 |
Not clear |
| Jérôme Ribot, Rachel Breton, Charles-Félix Calvo, Julien Moulard, Pascal Ezan, Jonathan Zapata, Kevin Samama, Matthieu Moreau, Alexis-Pierre Bemelmans, Valentin Sabatet, Florent Dingli, Damarys Loew, Chantal Milleret, Pierre Billuart, Glenn Dallérac, Nathalie Rouac. Astrocytes close the mouse critical period for visual plasticity. Science (New York, N.Y.). vol 373. issue 6550. 2021-07-13. PMID:34210880. |
unconventional astrocyte connexin signaling hinders expression of extracellular matrix-degrading enzyme matrix metalloproteinase 9 (mmp9) through rhoa-guanosine triphosphatase activation. |
2021-07-13 |
2023-08-13 |
mouse |
| Yunjuan Zhang, Zengyan Cai, Jin Liang, Erqing Chai, Anqing Lu, Yinwu Shan. CircCPA4 Promotes the Malignant Phenotypes in Glioma via miR-760/MEF2D Axis. Neurochemical research. vol 45. issue 12. 2021-07-12. PMID:33068224. |
western blot was used to detect the protein levels of matrix metallopeptidase 2 (mmp2), mmp9 and myocyte enhancer factor 2d (mef2d). |
2021-07-12 |
2023-08-13 |
Not clear |
| Jianghua Zheng, Qiang Tan, Hang Chen, Kai Chen, Haifei Wang, Zhilong Chen, Yong Xi, Hongshun Yin, Kun Lai, Yujuan Li. lncRNA‑SNHG7‑003 inhibits the proliferation, migration and invasion of vascular smooth muscle cells by targeting the miR‑1306‑5p/SIRT7 signaling pathway. International journal of molecular medicine. vol 47. issue 2. 2021-07-12. PMID:33416100. |
western blot analysis was also used to analyze the protein expression levels of α‑smooth muscle actin (α‑sma), matrix metalloproteinase (mmp)2 and mmp9. |
2021-07-12 |
2023-08-13 |
Not clear |
| Simin Luo, Wuji Li, Wenrui Wu, Qiping Sh. Elevated expression of MMP8 and MMP9 contributes to diabetic osteoarthritis progression in a rat model. Journal of orthopaedic surgery and research. vol 16. issue 1. 2021-07-12. PMID:33468174. |
previous studies have shown that matrix metalloproteinase (mmp) 8 and mmp9 were upregulated in patients with diabetic oa. |
2021-07-12 |
2023-08-13 |
rat |
| Chun-Kai Fu, Wen-Shin Chang, Chia-Wen Tsai, Yun-Chi Wang, Mei-Due Yang, Hua-Shai Hsu, Che-Yi Chao, Chien-Chih Yu, Jaw-Chyun Chen, Jen-Sheng Pei, DA-Tian Ba. The Association of Anticancer research. vol 41. issue 7. 2021-07-09. PMID:34230126. |
the association of matrix metalloproteinase 9 (mmp9) is highly expressed in gastric cancer but the role of mmp9 is unclear. |
2021-07-09 |
2023-08-13 |
Not clear |
| Hongyang Sui, Changju Zhu, Zhenzhen Li, Jianjun Yan. Propofol suppresses gastric cancer tumorigenesis by modulating the circular RNA‑PVT1/miR‑195‑5p/E26 oncogene homolog 1 axis. Oncology reports. vol 44. issue 4. 2021-07-06. PMID:32945521. |
western blotting was performed to detect the protein levels of cyclin‑dependent kinase inhibitor p21 (p21), b‑cell lymphoma‑2 (bcl‑2), matrix metalloproteinase 9 (mmp9) and e26 oncogene homolog 1 (ets1). |
2021-07-06 |
2023-08-13 |
mouse |