| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chuanbao Lin, Pengfei Qian, Yan Zhang, Zhihui Liu, Kun Dai, Dawei Su. Plac1 promotes nasopharyngeal carcinoma cells proliferation, migration and invasion via Furin/NICD/PTEN pathway. Tissue & cell. vol 69. 2021-10-07. PMID:33418237. |
relative expressions of plac1 and proteins related to migration and invasion (e-cadherin, n-cadherin, matrix metalloproteinase2 (mmp2), and mmp9), furin/notch1 intracellular domain (nicd)/phosphate and tension homology (pten) pathway (nicd, pten, phosphorylated-akt (p-akt), akt) were quantified by quantitative real-time polymerase chain reaction (qrt-pcr) and western blot as needed. |
2021-10-07 |
2023-08-13 |
human |
| Xingyu Yang, Dan Chen, Biwei He, Weiwei Chen. NRP1 and MMP9 are dual targets of RNA-binding protein QKI5 to alter VEGF-R/ NRP1 signalling in trophoblasts in preeclampsia. Journal of cellular and molecular medicine. vol 25. issue 12. 2021-10-01. PMID:33942999. |
further, similar to nrp1, qki5 also targets matrix metalloproteinase 9 (mmp9) involved in secretion of growth factors and its effects can be counteracted by nrp1 overexpression. |
2021-10-01 |
2023-08-13 |
mouse |
| Céleste M Chevalier, Luka Krampert, Monika Schreckenbach, Christine F Schubert, Johanna Reich, Bozidar Novak, Mathias V Schmidt, Bart P F Rutten, Ulrike Schmid. MMP9 mRNA is a potential diagnostic and treatment monitoring marker for PTSD: Evidence from mice and humans. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 51. 2021-10-01. PMID:34022747. |
although matrix metalloproteinase 9 (mmp9) has been found associated with various psychiatric disorders and with threat memories in humans, its role in post-traumatic stress disorder (ptsd) and related animal models is understudied. |
2021-10-01 |
2023-08-13 |
mouse |
| Lucía Beltrán-Camacho, Margarita Jiménez-Palomares, Ismael Sanchez-Gomar, Antonio Rosal-Vela, Marta Rojas-Torres, Sara Eslava-Alcon, Jose Angel Alonso-Piñero, Almudena González-Rovira, Mª Jesús Extremera-García, Rosario Conejero, Esther Doiz, Manuel Rodriguez-Piñero, Martin R Larsen, Mª Carmen Duran-Rui. Long Term Response to Circulating Angiogenic Cells, Unstimulated or Atherosclerotic Pre-Conditioned, in Critical Limb Ischemic Mice. Biomedicines. vol 9. issue 9. 2021-10-01. PMID:34572333. |
in addition, many proteins potentially involved, like cd44 or matrix metalloproteinase 9 (mmp9), up-regulated in response to ischemia and decreased after cacs administration, were identified by a quantitative proteomics approach. |
2021-10-01 |
2023-08-13 |
mouse |
| Yoon Seok Choi, Hyung Gyun Na, Chang Hoon Bae, Si-Youn Song, Yong-Dae Ki. Pepsin exposure in a non-acidic environment upregulates mucin 5AC (MUC5AC) expression via matrix metalloproteinase 9 (MMP9)/nuclear factor κB (NF-κB) in human airway epithelial cells. International forum of allergy & rhinology. vol 11. issue 5. 2021-09-29. PMID:32846027. |
pepsin exposure in a non-acidic environment upregulates mucin 5ac (muc5ac) expression via matrix metalloproteinase 9 (mmp9)/nuclear factor κb (nf-κb) in human airway epithelial cells. |
2021-09-29 |
2023-08-13 |
human |
| Chang-Hun Yeom, Hee-Jin Jeon. Production of a Soluble Recombinant Antibody Fragment against MMP9 Using Medicina (Kaunas, Lithuania). vol 57. issue 9. 2021-09-29. PMID:34577904. |
production of a soluble recombinant antibody fragment against mmp9 using matrix metalloproteinase 9 (mmp9) is involved in several aspects of the pathology of cancer, including invasion, metastasis, and angiogenesis. |
2021-09-29 |
2023-08-13 |
Not clear |
| Isadora Ramos-Andrade, João Moraes, Renata Machado Brandão-Costa, Simone Vargas da Silva, Antônio de Souza, César da Silva, Mariana Renovato-Martins, Christina Barja-Fidalg. Obese adipose tissue extracellular vesicles raise breast cancer cell malignancy. Endocrine-related cancer. vol 27. issue 10. 2021-09-28. PMID:32738129. |
we also detected that evs derived from obese at were enriched in leptin and bioactive matrix metallopeptidase 9 (mmp9), and stimulation of mda-md-231 cells with those evs or cm derived from obese at potentiated the release of mmp9 by those cells. |
2021-09-28 |
2023-08-13 |
human |
| Xue Li, Fan Wang, Yuanxin Lan, Ruyu Bian, Ying Wang, Xiaorong Zhang, Yicheng Guo, Ling Xiao, Wenqiang Ni, Xiaohong Zhao, Gaoxing Luo, Rixing Zha. GDF-5 induces epidermal stem cell migration via RhoA-MMP9 signalling. Journal of cellular and molecular medicine. vol 25. issue 4. 2021-09-23. PMID:33369147. |
western blot and real-time pcr assays demonstrated that the expression levels of rhoa and matrix metalloproteinase-9 (mmp9) were correlated with rmgdf-5 concentration. |
2021-09-23 |
2023-08-13 |
mouse |
| Lulu Su, Yinping Dong, Yueying Wang, Yuquan Wang, Bowen Guan, Yanhua Lu, Jing Wu, Xiaochun Wang, Deguan Li, Aimin Meng, Feiyue Fa. Potential role of senescent macrophages in radiation-induced pulmonary fibrosis. Cell death & disease. vol 12. issue 6. 2021-09-22. PMID:34023858. |
besides, there's a significant increase in the expression of pro-fibrogenic factors (tgf-β1 and arg-1), senescence-associated secretory phenotype (sasp) proinflammatory factors (il-1α, il-6, and tnf-α), sasp chemokines (ccl2, cxcl10, and ccl17), and sasp matrix metalloproteinases (mmp2, mmp9 and mmp12) in bmms exposed to 10 gy ir. |
2021-09-22 |
2023-08-13 |
Not clear |
| Jiangli Lang, Chen Yang, Lixuan Liu, Li Li, Liangyan Wu, Yanyan Liu, Hengli Luo, Li Yan, Sifan Chen, Jie Ning, Chuan Yan. High glucose activates ERK1/2 to stabilize AP1 and increase MMP9 expression in diabetic foot ulcers. Experimental cell research. vol 403. issue 1. 2021-09-21. PMID:33675806. |
increased matrix metalloproteinase 9 (mmp9) expression is involved in delayed wound healing in diabetic foot ulcers. |
2021-09-21 |
2023-08-13 |
rat |
| Haidong Lv, Dixia Zhou, Guoqing Li. LncRNA LINC00963 promotes colorectal cancer cell proliferation and metastasis by regulating miR‑1281 and TRIM65. Molecular medicine reports. vol 24. issue 5. 2021-09-18. PMID:34498706. |
functionally, linc00963 facilitated the proliferation, colony formation, migration and invasion of crc cells, and increased the expression levels of ki67, matrix metalloproteinase (mmp)2 and mmp9, while mir‑1281 had the opposite biological functions. |
2021-09-18 |
2023-08-13 |
Not clear |
| Rui Zhou, Changpei Xiang, Guangzhao Cao, He Xu, Yi Zhang, Hongjun Yang, Jingjing Zhan. Berberine accelerated wound healing by restoring TrxR1/JNK in diabetes. Clinical science (London, England : 1979). vol 135. issue 4. 2021-09-17. PMID:33491733. |
further analysis indicated that bbr activated trxr1, suppressed its downstream jnk signaling, thereby inhibiting oxidative stress and apoptosis, promoted cell proliferation, down-regulated matrix metalloproteinase (mmp) 9 (mmp9) and up-regulated transforming growth factor-β1 (tgf-β1) and tissue inhibitors of mmp 1 (timp1), resulting in accelerated wound healing. |
2021-09-17 |
2023-08-13 |
rat |
| Lewins Walter, Brandon Canup, Adani Pujada, Tien Anh Bui, Behafarin Arbasi, Hamed Laroui, Didier Merlin, Pallavi Gar. Matrix metalloproteinase 9 (MMP9) limits reactive oxygen species (ROS) accumulation and DNA damage in colitis-associated cancer. Cell death & disease. vol 11. issue 9. 2021-09-14. PMID:32943603. |
matrix metalloproteinase 9 (mmp9) limits reactive oxygen species (ros) accumulation and dna damage in colitis-associated cancer. |
2021-09-14 |
2023-08-13 |
mouse |
| Lewins Walter, Brandon Canup, Adani Pujada, Tien Anh Bui, Behafarin Arbasi, Hamed Laroui, Didier Merlin, Pallavi Gar. Matrix metalloproteinase 9 (MMP9) limits reactive oxygen species (ROS) accumulation and DNA damage in colitis-associated cancer. Cell death & disease. vol 11. issue 9. 2021-09-14. PMID:32943603. |
matrix metalloproteinase 9 (mmp9) is a zinc-dependent endopeptidase against extracellular matrix (ecm) proteins expressed in the gastrointestinal tract during inflammation. |
2021-09-14 |
2023-08-13 |
mouse |
| Yong Jin, Manling Zhang, Meishuang Li, Hong Zhang, Lihua Zhao, Cheng Qian, Shensen Li, Hao Zhang, Min Gao, Binbin Pan, Rongfeng Li, Xin Wan, Changchun Ca. SIX1 Activation Is Involved in Cell Proliferation, Migration, and Anti-inflammation of Acute Ischemia/Reperfusion Injury in Mice. Frontiers in molecular biosciences. vol 8. 2021-09-14. PMID:34513929. |
we demonstrated that six1 promoted cell proliferation by upregulating cyclin and glycolytic genes, and might increase cell migration by upregulating the expression of matrix metalloproteinase 9 (mmp9) directly or indirectly in the cell model. |
2021-09-14 |
2023-08-13 |
mouse |
| M Elizabeth Fini, Shinwu Jeong, Mark R Wilso. Therapeutic Potential of the Molecular Chaperone and Matrix Metalloproteinase Inhibitor Clusterin for Dry Eye. International journal of molecular sciences. vol 22. issue 1. 2021-09-13. PMID:33374364. |
this idea began with the demonstration that matrix metalloproteinase mmp9 is required for damage to the ocular surface in mouse dry eye. |
2021-09-13 |
2023-08-13 |
mouse |
| Gal Yosef, Hezi Hayun, Niv Pap. Simultaneous targeting of CD44 and MMP9 catalytic and hemopexin domains as a therapeutic strategy. The Biochemical journal. vol 478. issue 5. 2021-09-13. PMID:33600567. |
crosstalk of the oncogenic matrix metalloproteinase-9 (mmp9) and one of its ligands, cd44, involves cleavage of cd44 by the mmp9 catalytic domain, with the cd44-mmp9 interaction on the cell surface taking place through the mmp9 hemopexin domain (pex). |
2021-09-13 |
2023-08-13 |
Not clear |
| J Humberto Treviño-Villarreal, Justin S Reynolds, P Kent Langston, Andrew Thompson, James R Mitchell, Ramon A Franc. Down-Regulation of a Profibrotic Transforming Growth Factor-β1/Cellular Communication Network Factor 2/Matrix Metalloprotease 9 Axis by Triamcinolone Improves Idiopathic Subglottic Stenosis. The American journal of pathology. vol 191. issue 8. 2021-09-13. PMID:34111429. |
mechanistically, silsi counteracted the effects of tgf-β1 by inducing matrix metalloprotease 9 (mmp9) expression while repressing ccn2 expression, without affecting tgfβ1 levels. |
2021-09-13 |
2023-08-13 |
Not clear |
| Tan Li, Xintong Li, Xiaozheng Liu, Jun Yang, Chunyan M. The elevated expression of TLR4 and MMP9 in human abdominal aortic aneurysm tissues and its implication. BMC cardiovascular disorders. vol 21. issue 1. 2021-09-13. PMID:34348653. |
toll-like receptor 4 (tlr4) and matrix metalloproteinase 9 (mmp9) have been investigated to play significant roles in the formation of abdominal aortic aneurysm (aaa). |
2021-09-13 |
2023-08-13 |
human |
| Qiongyan Zou, Wenjun Yi, Jianghai Huang, Fenfen Fu, Gannong Chen, Dewu Zhon. MicroRNA-375 targets PAX6 and inhibits the viability, migration and invasion of human breast cancer MCF-7 cells. Experimental and therapeutic medicine. vol 14. issue 2. 2021-09-10. PMID:28810579. |
the increase in mir-375 expression caused a significant decrease in the viability, migration and invasion of mcf-7 cells (p<0.05), accompanied by a reduced expression of matrix metalloproteinase (mmp) 2 and mmp9 proteins. |
2021-09-10 |
2023-08-13 |
human |