| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alaa Elmetwalli, Thoria Diab, Aisha Nawaf Albalawi, Sabry Ali El-Naggar, Ali H El-Far, Amira Radwan Ghedan, Eman Saad Alamri, Afrah Fatthi Salam. Diarylheptanoids/sorafenib as a potential anticancer combination against hepatocellular carcinoma: the p53/MMP9 axis of action. Naunyn-Schmiedeberg's archives of pharmacology. 2023-05-05. PMID:37145126. |
the apoptosis-related gene (casp8), the apoptosis-related gene (p53), the anti-inflammatory genes (il-6), the migration-related gene matrix metalloprotease-9 (mmp9), and the angiogenesis-related gene vascular endothelial growth factor (vegf) were assessed using qrt-pcr in the hepatic tissue. |
2023-05-05 |
2023-08-14 |
mouse |
| Anis Barmada, Jon Klein, Anjali Ramaswamy, Nina N Brodsky, Jillian R Jaycox, Hassan Sheikha, Kate M Jones, Victoria Habet, Melissa Campbell, Tomokazu S Sumida, Amy Kontorovich, Dusan Bogunovic, Carlos R Oliveira, Jeremy Steele, E Kevin Hall, Mario Pena-Hernandez, Valter Monteiro, Carolina Lucas, Aaron M Ring, Saad B Omer, Akiko Iwasaki, Inci Yildirim, Carrie L Luca. Cytokinopathy with aberrant cytotoxic lymphocytes and profibrotic myeloid response in SARS-CoV-2 mRNA vaccine-associated myocarditis. Science immunology. vol 8. issue 83. 2023-05-05. PMID:37146127. |
instead, unbiased systematic immune serum profiling revealed elevations in circulating interleukins (il-1β, il-1ra, and il-15), chemokines (ccl4, cxcl1, and cxcl10), and matrix metalloproteases (mmp1, mmp8, mmp9, and timp1). |
2023-05-05 |
2023-08-14 |
Not clear |
| Xavier Capó, Margalida Monserrat-Mesquida, Magdalena Quetglas-Llabrés, Juan M Batle, Josep A Tur, Antoni Pons, Antoni Sureda, Silvia Tejad. Hyperbaric Oxygen Therapy Reduces Oxidative Stress and Inflammation, and Increases Growth Factors Favouring the Healing Process of Diabetic Wounds. International journal of molecular sciences. vol 24. issue 8. 2023-04-28. PMID:37108205. |
plasma levels of growth factors--platelet-derived growth factor (pdfg), transforming growth factor β (tgf-β) and hypoxia-inducible factor 1-alpha (hif-1α)-- were increased as a consequence of hbot and reduced 28 days after complete wound healing, whereas matrix metallopeptidase 9 (mmp9) progressively decreased with the hbot. |
2023-04-28 |
2023-08-14 |
human |
| Yen-Yu Yang, Ruthia Soh, Madeline Vera-Colón, Ming Huang, Nicole I Zur Nieden, Yinsheng Wan. Targeted Proteomic Profiling Revealed Roles of Small GTPases during Osteogenic Differentiation. Analytical chemistry. 2023-04-21. PMID:37083350. |
we also documented a previously unrecognized role of kras in osteogenesis, where it regulates the accumulation of extracellular matrix for mineralization through attenuating the activity of secreted matrix metalloproteinase 9 (mmp9). |
2023-04-21 |
2023-08-14 |
human |
| Joseph H McCart. MMP9 Clears the Way for Metastatic Cell Penetration Across the Blood-Brain Barrier. Cancer research. vol 83. issue 8. 2023-04-14. PMID:37057598. |
they show that matrix metalloprotease 9 (mmp9) plays a central role in these events. |
2023-04-14 |
2023-08-14 |
Not clear |
| Joseph H McCart. MMP9 Clears the Way for Metastatic Cell Penetration Across the Blood-Brain Barrier. Cancer research. vol 83. issue 8. 2023-04-14. PMID:37057598. |
surprisingly, extravasation and brain colonization does not involve significant degradation of canonical mmp9 protein targets such as collagen and laminin in vascular basement membranes, indicating the requirement for other extracellular matrix (ecm) or non-ecm substrates for mmp9. |
2023-04-14 |
2023-08-14 |
Not clear |
| Jing-Yu Qu, Hua-Tao Xie, Yu-Ting Xiao, Ying-Ying Zhang, Zhi-Xin Hu, Jia-Song Wang, Ming-Chang Zhang, Han X. The inhibition of p38 MAPK blocked inflammation to restore the functions of rat meibomian gland epithelial cells. Experimental eye research. 2023-04-14. PMID:37059216. |
cell proliferation, keratinization, lipid accumulation, and matrix metalloproteinases 9 (mmp9) expression were evaluated by mtt assay, polymerase chain reaction (pcr), immunofluorescence staining, apoptosis assay, lipid staining, and western blot analyses. |
2023-04-14 |
2023-08-14 |
mouse |
| Alaleh Mohammadi, Souzan Najafi, Mohammad Amini, Behzad Baradaran, Masoumeh Firouzamand. B7H6 silencing increases chemosensitivity to dacarbazine and suppresses cell survival and migration in cutaneous melanoma. Melanoma research. 2023-04-13. PMID:37053079. |
b7h6 suppression combined with dacarbazine restrained cell migration through suppression of matrix metalloproteinase (mmp) expression, including mmp2, mmp3, and mmp9. |
2023-04-13 |
2023-08-14 |
Not clear |
| Qiang Zhang, Ting Luo, Dezheng Yuan, Jing Liu, Yi Fu, Jiali Yua. Qilongtian ameliorate bleomycin-induced pulmonary fibrosis in mice via inhibiting IL-17 signal pathway. Scientific reports. vol 13. issue 1. 2023-04-12. PMID:37045911. |
further studies indicated that qlt reduced the mrnas and protein levels of interleukin 17 (il-17), c-c motif chemokine ligand 12 (ccl12), c-x-c motif chemokine ligand 5 (cxcl5), fos-like antigen 1 (fosl1), matrix metalloproteinase-9 (mmp9), and amphiregulin (areg), which are inflammation and fibrosis-related genes in the il-17 signal pathway. |
2023-04-12 |
2023-08-14 |
mouse |
| Eun-Gene Sun, Veena Vijayan, Mi-Ra Park, Kyung Hyun Yoo, Sang-Hee Cho, Woo-Kyun Bae, Hyun-Jeong Shim, Jun-Eul Hwang, In-Kyu Park, Ik-Joo Chun. Suppression of triple-negative breast cancer aggressiveness by LGALS3BP via inhibition of the TNF-α-TAK1-MMP9 axis. Cell death discovery. vol 9. issue 1. 2023-04-11. PMID:37041137. |
lgals3bp inhibited tnf-α-mediated gene expression of matrix metalloproteinase 9 (mmp9), which encodes a protein crucial for lung metastasis in tnbc patients. |
2023-04-11 |
2023-08-14 |
Not clear |
| Guo Zheng, Yu Su, Li Wei, Yingcheng Yao, Yizhe Wang, Xiaoting Luo, Xing Wang, Xiong Z Ruan, Danyang Li, Yaxi Che. SCAP contributes to embryonic angiogenesis by negatively regulating KISS-1 expression in mice. Cell death & disease. vol 14. issue 4. 2023-04-06. PMID:37024487. |
mechanistically, we demonstrated that scap ablation in vsmcs leads to the upregulation of kiss-1 protein, consequently resulting in suppressed activation of the mapk/erk signaling pathway and downregulation of matrix metalloproteinase 9 (mmp9) and vascular endothelial-derived growth factor (vegf) expression to prevent angiogenesis. |
2023-04-06 |
2023-08-14 |
mouse |
| Yuye Wang, Luying Qiu, Shumin Deng, Fang Liu, Zhiyi He, Mengye Li, Yanzhe Wan. Ursolic Acid Promotes Microglial Polarization Toward the M2 Phenotype Via PPARγ Regulation of MMP2 Transcription. Neurotoxicology. 2023-04-05. PMID:37019307. |
additionally, ua increases tissue inhibitor matrix metalloproteinase 1 (timp1), while greatly reducing the release of matrix metalloproteinase 2 (mmp2) and mmp9 in a pparγ-dependent manner. |
2023-04-05 |
2023-08-14 |
rat |
| Meng Wang, Xin Yu, Bin Li, Chensong Gao, Yan Chen, Xiaoyang Zhang, Wenling Li, Lijun Yang, Zhenzeng Fa. miR-211-5p targeting MMP9 regulates the expressions of AQP4 in traumatic brain injury. Acta neurologica Belgica. 2023-04-05. PMID:37020131. |
the abnormal expression of matrix metalloproteinase 9 (mmp9) and aquaporin 4 (aqp4) closely associates with the traumatic brain injury (tbi) development. |
2023-04-05 |
2023-08-14 |
Not clear |
| Sarah Albogam. The Potential Inhibitory Role of Acetyl-L-Carnitine on Proliferation, Migration, and Gene Expression in HepG2 and HT29 Human Adenocarcinoma Cell Lines. Current issues in molecular biology. vol 45. issue 3. 2023-03-28. PMID:36975525. |
the relative mrna expressions of matrix metallopeptidase 9 (mmp9) and vascular endothelial growth factor (vegf) were evaluated using rt-pcr. |
2023-03-28 |
2023-08-14 |
human |
| Takeshi Yamasaki, Noriyuki Nagata, Toru Atsumi, Rie Hasebe, Yuki Tanaka, Izuru Ohki, Shimpei Kubota, Yuta Shinohara, Yong Bin Teoh, Nozomu Yokoyama, Noboru Sasaki, Kensuke Nakamura, Hiroshi Ohta, Takehiko Katsurada, Yoshihiro Matsuno, Shintaro Hojyo, Shigeru Hashimoto, Mitsuyoshi Takiguchi, Masaaki Murakam. Zoobiquity experiments show the importance of the local MMP9-plasminogen axis in inflammatory bowel diseases in both dogs and patients. International immunology. 2023-03-18. PMID:36933193. |
using a zoobiquity concept, we directly connect animal phenotypes to a human disease mechanism: the reduction of local plasminogen levels caused by matrix metalloproteinase-9 (mmp9) activity is associated with the development of inflammation in the intestines of dogs and patients with inflammatory bowel disease. |
2023-03-18 |
2023-08-14 |
human |
| Rafał Adamczak, Natalia Ukleja-Sokołowska, Kinga Lis, Zbigniew Bartuzi, Mariusz Dubie. Assessment of RANTES, MIP4A, MMP7, MMP9, MMP14, TIMP 1, TIMP 2 and TIMP 3 concentration in the follicular fluid of patients undergoing Postepy dermatologii i alergologii. vol 40. issue 1. 2023-03-13. PMID:36909896. |
assessment of rantes, mip4a, mmp7, mmp9, mmp14, timp 1, timp 2 and timp 3 concentration in the follicular fluid of patients undergoing matrix metalloproteinases (mmp) degrade extracellular matrix. |
2023-03-13 |
2023-08-14 |
Not clear |
| Asmaa S A Hammad, Mohamed M Sayed-Ahmed, Sara M N Abdel Hafez, Ahmed R N Ibrahim, Mohamed M A Khalifa, Mahmoud El-Dal. Trimetazidine alleviates paclitaxel-induced peripheral neuropathy through modulation of TLR4/p38/NFκB and klotho protein expression. Chemico-biological interactions. 2023-03-10. PMID:36898573. |
the results of the current study show that the neuroprotective effect of tmz can be attributed to inhibition of tlr4/p38 signaling which also includes a reduction in matrix metalloproteinase-9 (mmp9) protein levels as well as the proinflammatory interleukin-1β (il-1β) and preserving the levels of the anti-inflammatory il-10. |
2023-03-10 |
2023-08-14 |
mouse |
| Ping-Chih Hsu, Jhy-Ming Li, Cheng-Ta Yan. Forced Overexpression of Signal Transducer and Activator of Transcription 3 (STAT3) Activates Yes-Associated Protein (YAP) Expression and Increases the Invasion and Proliferation Abilities of Small Cell Lung Cancer (SCLC) Cells. Biomedicines. vol 10. issue 7. 2023-03-08. PMID:35885009. |
we showed that stat3 overexpression promoted emt (epithelial−mesenchymal transition) with increased matrix metalloproteinase (mmp)-2 and mmp9 expression. |
2023-03-08 |
2023-08-16 |
mouse |
| Keke Huang, Xin Liu, Ziru Lv, Di Zhang, Yuling Zhou, Zhiqing Lin, Juan Gu. MMP9-Responsive Graphene Oxide Quantum Dot-Based Nano-in-Micro Drug Delivery System for Combinatorial Therapy of Choroidal Neovascularization. Small (Weinheim an der Bergstrasse, Germany). 2023-03-05. PMID:36871144. |
age-related macular degeneration (amd), especially wet amd with choroidal neovascularization (cnv), commonly causes blindness in older patients and disruption of the choroid followed by second-wave injuries, including chronic inflammation, oxidative stress, and excessive matrix metalloproteinase 9 (mmp9) expression. |
2023-03-05 |
2023-08-14 |
mouse |
| Yae Hidaka, Shinsuke Nakamura, Anri Nishinaka, Yuichi Takajo, Satoshi Inamasu, Satoshi Yomoda, Masamitsu Shimazawa, Hideaki Har. Arctigenin Prevents Retinal Edema in a Murine Retinal Vein Occlusion Model. Biological & pharmaceutical bulletin. vol 46. issue 3. 2023-03-01. PMID:36858576. |
moreover, in retinas with edema, arctigenin suppressed the induction of vegf, tumor necrosis factor α (tnfα), and matrix metallopeptidase 9 (mmp9). |
2023-03-01 |
2023-08-14 |
human |