| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Asmaa S A Hammad, Mohamed M Sayed-Ahmed, Sara M N Abdel Hafez, Ahmed R N Ibrahim, Mohamed M A Khalifa, Mahmoud El-Dal. Trimetazidine alleviates paclitaxel-induced peripheral neuropathy through modulation of TLR4/p38/NFκB and klotho protein expression. Chemico-biological interactions. 2023-03-10. PMID:36898573. |
the results of the current study show that the neuroprotective effect of tmz can be attributed to inhibition of tlr4/p38 signaling which also includes a reduction in matrix metalloproteinase-9 (mmp9) protein levels as well as the proinflammatory interleukin-1β (il-1β) and preserving the levels of the anti-inflammatory il-10. |
2023-03-10 |
2023-08-14 |
mouse |
| Ping-Chih Hsu, Jhy-Ming Li, Cheng-Ta Yan. Forced Overexpression of Signal Transducer and Activator of Transcription 3 (STAT3) Activates Yes-Associated Protein (YAP) Expression and Increases the Invasion and Proliferation Abilities of Small Cell Lung Cancer (SCLC) Cells. Biomedicines. vol 10. issue 7. 2023-03-08. PMID:35885009. |
we showed that stat3 overexpression promoted emt (epithelial−mesenchymal transition) with increased matrix metalloproteinase (mmp)-2 and mmp9 expression. |
2023-03-08 |
2023-08-16 |
mouse |
| Keke Huang, Xin Liu, Ziru Lv, Di Zhang, Yuling Zhou, Zhiqing Lin, Juan Gu. MMP9-Responsive Graphene Oxide Quantum Dot-Based Nano-in-Micro Drug Delivery System for Combinatorial Therapy of Choroidal Neovascularization. Small (Weinheim an der Bergstrasse, Germany). 2023-03-05. PMID:36871144. |
age-related macular degeneration (amd), especially wet amd with choroidal neovascularization (cnv), commonly causes blindness in older patients and disruption of the choroid followed by second-wave injuries, including chronic inflammation, oxidative stress, and excessive matrix metalloproteinase 9 (mmp9) expression. |
2023-03-05 |
2023-08-14 |
mouse |
| Yae Hidaka, Shinsuke Nakamura, Anri Nishinaka, Yuichi Takajo, Satoshi Inamasu, Satoshi Yomoda, Masamitsu Shimazawa, Hideaki Har. Arctigenin Prevents Retinal Edema in a Murine Retinal Vein Occlusion Model. Biological & pharmaceutical bulletin. vol 46. issue 3. 2023-03-01. PMID:36858576. |
moreover, in retinas with edema, arctigenin suppressed the induction of vegf, tumor necrosis factor α (tnfα), and matrix metallopeptidase 9 (mmp9). |
2023-03-01 |
2023-08-14 |
human |
| Ke Jiang, Yuling Li, Chao Xiang, Yan Xiong, Jiameng Ji. Rebalancing Smad7/Smad3 Signaling Reduces Adhesion Formation during Flexor Tendon Healing. Journal of microbiology and biotechnology. vol 33. issue 3. 2023-03-01. PMID:36859314. |
the mrna levels of matrix metalloproteinase (mmp)2, mmp9, and scleraxis (scx) in flexor tendon tissue were detected by rt-qpcr. |
2023-03-01 |
2023-08-14 |
mouse |
| Wei Liu, Chenggao Wu, Qian Wang, Linju Kuang, Aiping L. Tanshinone IIA relieves arthritis by inhibiting autophagy of fibroblast-like synoviocytes via matrix metalloproteinase9/receptor for advanced glycation end product/toll-like receptor 9 signal axis in mice with collagen-induced arthritis. Phytotherapy research : PTR. 2023-02-28. PMID:36852883. |
gain- or loss-of-function approaches were used to manipulate matrix metalloproteinase9 (mmp9), receptor for advanced glycation end product (rage), and toll-like receptor 9 (tlr9) in both cia mice and ra-flss following treatment with tiia to study the in vivo and in vitro effect of tiia through analysis of cell viability, and measurement of autophagy and inflammatory proteins as well as severity of ra. |
2023-02-28 |
2023-08-14 |
mouse |
| Bin Zhang, Kuan Zeng, Rui-Cong Guan, Hui-Qi Jiang, Yong-Jia Qiang, Qing Zhang, Mo Yang, Bao-Ping Deng, Yan-Qi Yan. Single-Cell RNA-Seq Analysis Reveals Macrophages Are Involved in the Pathogenesis of Human Sporadic Acute Type A Aortic Dissection. Biomolecules. vol 13. issue 2. 2023-02-25. PMID:36830768. |
finally, immunohistochemistry, immunofluorescence, and western blot experiments confirmed the overexpression of macrophage marker genes (cd68 and cd163) and matrix metalloproteinases (mmp9 and mmp2) in ataad tissue. |
2023-02-25 |
2023-08-14 |
human |
| Zalinah Ahmad, Joan Blin, Lekhraj Rampal, Rohayu Shahar Adnan, Norhafizah Mohtarrudin, Dayang Sarah Yasmine Abang Yusu. Association of LDLR, TP53 and MMP9 Gene Polymorphisms with Atherosclerosis in a Malaysian Study Population. Current problems in cardiology. 2023-02-23. PMID:36822563. |
preliminary research has shown that low density lipoprotein receptor (ldlr), tumor protein (tp53) and matrix metalloproteinase 9 (mmp9) genes expression levels were significantly increased in atherosclerosis coronary artery tissue (acat) compared to non-atherosclerotic coronary artery tissue (ncat) samples. |
2023-02-23 |
2023-08-14 |
Not clear |
| Maile Velasquez, Chris O'Sullivan, Robert Brockett, Amanda Mikels-Vigdal, Igor Mikaelian, Victoria Smith, Andrew E Greenstei. Characterization of Active MMP9 in Chronic Inflammatory Diseases Using a Novel Anti-MMP9 Antibody. Antibodies (Basel, Switzerland). vol 12. issue 1. 2023-02-22. PMID:36810514. |
matrix metalloproteinase 9 (mmp9), a protease implicated in multiple diseases, is secreted as an inactive zymogen and requires proteolytic removal of the pro-domain for activation. |
2023-02-22 |
2023-08-14 |
Not clear |
| Satadruti Chakraborty, Turuvekere Narayan Rao Suresh, Azeem S Mohiyuddi. Role of Matrix Metalloproteinase 9 in Predicting Lymph Node Metastases in Oral Squamous Cell Carcinoma. Cureus. vol 15. issue 1. 2023-02-09. PMID:36756017. |
of the different subtypes, multiple studies have demonstrated that matrix metalloproteinase 9 (mmp9) overexpression is often associated with the aggressive nature of the tumor. |
2023-02-09 |
2023-08-14 |
Not clear |
| Junichi Saito, Hailin Zao, Lingzhi Wu, Masae Iwasaki, Qizhe Sun, Cong Hu, Masashi Ishikawa, Kazuyoshi Hirota, Daqing M. "Anti-cancer" effect of ketamine in comparison with MK801 on neuroglioma and lung cancer cells. European journal of pharmacology. 2023-02-09. PMID:36758782. |
cyclin d1, matrix metalloproteinase 9 (mmp9), phosphorylation of extracellular signal-regulated kinase (perk), and cleaved-caspase-3 expression together with reactive oxygen species (ros) were also assessed with western blot, immunostaining, and/or flowcytometry. |
2023-02-09 |
2023-08-14 |
Not clear |
| Marwa Ahmed Abdelfattah, Ayman Saber Mohamed, Sherif Abdelaziz Ibrahim, Sohair R Fahm. Allolobophora caliginosa coelomic fluid and extract alleviate glucocorticoid-induced osteoporosis in mice by suppressing oxidative stress and regulating osteoblastic/osteoclastic-related markers. Scientific reports. vol 13. issue 1. 2023-02-06. PMID:36746995. |
treatment with ace and accf modulates oxidative stress and downregulated rank and mmp9 expression, as well as increased glycosaminoglycan content in the organic bone matrix, resulting in osteoclastogenesis inhibition. |
2023-02-06 |
2023-08-14 |
mouse |
| Bing-Qi Dong, Zhi-Kai Liao, Yue Le, Shan Jiang, Long-Fei Luo, Fang Miao, I Caroline Le Poole, Tie-Chi Le. Acceleration of melanocyte senescence by the proinflammatory cytokines IFNγ and TNFα impairs the repigmentation response of vitiligo patients to narrowband ultraviolet B (NBUVB) phototherapy. Mechanisms of ageing and development. 2023-02-02. PMID:36731753. |
furthermore, the matrix metalloprotease 9 (mmp9) inhibitor gm6001 attenuates the production of skit via the suppression of ckit ectodomain shedding. |
2023-02-02 |
2023-08-14 |
human |
| Xiang Wang, Mao Huang, Weiping Xie, Qingqing Ding, Tongshan Wan. Eupafolin regulates non-small-cell lung cancer cell proliferation,migration, and invasion by suppressing MMP9 and RhoA via FAK/PI3K/AKT signaling pathway. Journal of biosciences. vol 48. 2023-01-25. PMID:36695419. |
western blot assay was performed to measure the relative protein expressions of phosphorylated (p)-fak/fak, p-pi3k/ pi3k, p-akt/akt, matrix metalloproteinase 9 (mmp9), and |
2023-01-25 |
2023-08-14 |
Not clear |
| Silja Voß, Till Behrmann, Stephan Reich. Development of In Vitro Dry Eye Models to Study Proliferative and Anti-Inflammatory Effects of Allogeneic Serum Eye Drops. International journal of molecular sciences. vol 24. issue 2. 2023-01-21. PMID:36675083. |
interleukin-1β (il-1β) and tumor necrosis factor α (tnfα) were used to induce the gene expression of matrix metalloproteinase 9 (mmp9), cyclooxygenase 2 (cox2), transforming growth factor-β (tgfβ) and il-1β. |
2023-01-21 |
2023-08-14 |
human |
| Claire J Houchen, Bethany Castro, Portia Hahn Leat, Nashwa Mohammad, Faith Hall-Glenn, Erin E Buman. Treatment with an Inhibitor of Matrix Metalloproteinase 9 or Cathepsin K Lengthens Embryonic Lower Jaw Bone. Orthodontics & craniofacial research. 2023-01-21. PMID:36680416. |
our objective was to determine the effect of inhibiting osteoclast-secreted proteolytic enzymes on lower jaw bone length of avian embryos by pharmacologically inhibiting matrix metalloproteinase-9 (mmp9) or cathepsin k (ctsk). |
2023-01-21 |
2023-08-14 |
Not clear |
| Weiwei Chen, Daguang Ni, Hailin Zhang, Xia Li, Youqin Jiang, Jixiang Wu, Yan Gu, Mingcheng Gao, Woda Shi, Jianxiang Song, Wenyu Sh. Over-expression of USP15/MMP3 predict poor prognosis and promote growth, migration in non-small cell lung cancer cells. Cancer genetics. vol 272-273. 2023-01-14. PMID:36640492. |
biochemical analysis revealed that usp15 knockdown inhibited matrix metalloproteinase (mmp)3 and mmp9 expression. |
2023-01-14 |
2023-08-14 |
Not clear |
| Bowen Yang, Qiuwen Zhu, Xiaodong Wang, Jingxin Mao, Shuqing Zho. Using network pharmacology and molecular docking verification to explore the mechanism of ursolic acid in the treatment of osteoporosis. Medicine. vol 101. issue 49. 2023-01-10. PMID:36626454. |
a total of 24 core target genes were obtained, mainly including tumor protein p53 (tp53), vascular endothelial growth factor a (vegfa), interleukin-6 (il6), tumor necrosis factor (tnf), caspase3 (casp3), matrix metallo protein (mmp9), transcription factor ap-1 (jun), activator of transcription 3 (stat3), mitogen-activated protein kinase 8 (mapk8), and prostaglandin endoperoxidase 2 (ptgs2), respectively. |
2023-01-10 |
2023-08-14 |
Not clear |
| Suresh C Tyagi, Sathnur Pushpakumar, Utpal Sen, Sri Prakash L Mokshagundam, Dinesh K Kalra, Mohamed A Saad, Mahavir Sing. COVID-19 Mimics Pulmonary Dysfunction in Muscular Dystrophy as a Post-Acute Syndrome in Patients. International journal of molecular sciences. vol 24. issue 1. 2023-01-08. PMID:36613731. |
previously, we have shown the role of matrix metalloproteinase-9 (mmp9) in skeletal muscle fibrosis via a substantial increase in the levels of tumor necrosis factor-α (tnf-α) employing a dmd mouse model that was crossed-bred with mmp9-knockout (mmp9-ko or mmp9 |
2023-01-08 |
2023-08-14 |
mouse |
| Jonas Wagner, Yogesh Kumar, Anne Lautenbach, Philipp von Kroge, Stefan Wolter, Oliver Mann, Jakob Izbicki, Nicola Gagliani, Anna Dupré. Fatty acid-binding protein-4 (FABP4) and matrix metalloproteinase-9 (MMP9) as predictive values for nonalcoholic steatohepatitis (NASH). Lipids in health and disease. vol 22. issue 1. 2023-01-07. PMID:36609276. |
fatty acid-binding protein-4 (fabp4) and matrix metalloproteinase-9 (mmp9) as predictive values for nonalcoholic steatohepatitis (nash). |
2023-01-07 |
2023-08-14 |
Not clear |