| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Linping Wang, Luyi Chen, Daniel Schlenk, Feixue Li, Jing Li. Parabens promotes invasive properties of multiple human cells: A potential cancer-associated adverse outcome pathway. The Science of the total environment. 2024-03-28. PMID:38547973. |
mp and pp up-regulated the expression levels and enzymatic activities of matrix metalloproteinase 2 and 9 (mmp2 and mmp9), as well as altered the expression of the tissue inhibitors of metalloproteinase 1 and 2 (timp1 and timp2) in four cell lines, suggesting mmps/timps as potential key events (kes) for paraben-induced cell invasion. |
2024-03-28 |
2024-03-31 |
human |
| Yan Yang, Yue Cheng, Yanfei Mu, Xianjun Tang, Xiaosong M. Lentinan inhibits cell invasion via M2 polarization of tumor-associated macrophages and Wnt/β-catenin signaling in non-small cell lung cancer. Chemical biology & drug design. vol 103. issue 3. 2024-03-27. PMID:38538070. |
matrix metallopeptidase 9 (mmp9) levels were measured through immunofluorescence staining. |
2024-03-27 |
2024-03-30 |
Not clear |
| Bogdan Stelian Mastalier Manolescu, Angela Mădălina Lazar, George Sorin Ţiplica, Sabina Andrada Zurac, Adrian Reboşapcă, Bogdan Andreescu, Cristiana Gabriela Pop. MMP1, MMP9, MMP11 and MMP13 in melanoma and its metastasis - key points in understanding the mechanisms and celerity of tumor dissemination. Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. vol 65. issue 1. 2024-03-26. PMID:38527983. |
matrix metalloproteinase (mmp)1, mmp9, mmp11, and mmp13 are overexpressed in malignant melanoma (mm), being associated with tumor invasive phase, metastases, and more aggressive neoplastic phenotypes. |
2024-03-26 |
2024-03-28 |
Not clear |
| Haotian Zheng, Linxin Yang, Huashang Huang, Yazhou Lin, Lin Che. Morroniside improves AngII-induced cardiac fibroblast proliferation, migration, and extracellular matrix deposition by blocking p38/JNK signaling pathway through the downregulation of KLF5. Naunyn-Schmiedeberg's archives of pharmacology. 2024-03-13. PMID:38472369. |
in this study, it was found that mor treatment inhibited angii-induced hyperproliferation, migration, and fibrosis of hcf cells, accompanied with decreased activities of matrix metalloproteinase 2 (mmp2), matrix metalloproteinase 9 (mmp9), connective tissue growth factor (ctgf), fibronectin, and α-sma, which were all reversed by klf5 overexpression. |
2024-03-13 |
2024-03-15 |
human |
| Anthony Altieri, Courtney Lynn Marshall, Padmanie Ramotar, Dylan Lloyd, Mahadevappa Hemshekhar, Victor Spicer, Anne M van der Does, Neeloffer Mookherje. Human host defence peptide LL-37 suppresses TNFα-mediated matrix metalloproteinases MMP9 and MMP13, in human bronchial epithelial cells. Journal of innate immunity. 2024-03-12. PMID:38471488. |
human host defence peptide ll-37 suppresses tnfα-mediated matrix metalloproteinases mmp9 and mmp13, in human bronchial epithelial cells. |
2024-03-12 |
2024-03-15 |
human |
| Daniel Jussen, Syamend Saeed, Tatjana Jablonski, Harald Krenzlin, Kristin Lucia, Tobias Kraemer, Oliver Kempski, Marcus Czabanka, Florian Ringel, Beat Alessandr. Influence of Blood Components on Neuroinflammation, Blood-Brain Barrier Breakdown, and Functional Damage After Acute Subdural Hematoma in Rats. Neurotrauma reports. vol 5. issue 1. 2024-03-11. PMID:38463418. |
integrity of the bbb was evaluated with albumin and matrix metalloproteinase 9 (mmp9) staining. |
2024-03-11 |
2024-03-14 |
rat |
| Xiaolin Chen, Ningyuan Wang, Chenyang Jing, Jianghan Li, Xuanhao Liu, Yuquan Yang, Tianhuan Song, Hao Ji. The TGF-β/MMP9/RAGE axis induces sRAGE secretion by neutrophils and promotes oral carcinogenesis. Biochemistry and biophysics reports. vol 38. 2024-03-11. PMID:38463640. |
tgf-β was found to induce the expression of rage and matrix metalloproteinase 9 (mmp9) in neutrophils. |
2024-03-11 |
2024-03-14 |
mouse |
| Suvendu Nandi, Soumyadeep Bhaduri, Debraj Das, Priya Ghosh, Mahitosh Mandal, Pralay Mitr. Deciphering the Lexicon of Protein Targets: A Review on Multifaceted Drug Discovery in the Era of Artificial Intelligence. Molecular pharmaceutics. 2024-03-11. PMID:38466810. |
we have also demonstrated the pathological conditions of heat shock protein 27 (hsp27) and matrix metallopoproteinases (mmp2 and mmp9) and designed inhibitors of these proteins using the drug discovery paradigm in a case study on the discovery of drug molecules for cancer treatment. |
2024-03-11 |
2024-03-14 |
Not clear |
| Ajwan Z Albalawi, Areej S Alatawi, Shekha M Al-Atwi, Lama S Alhwyty, Kadi M Alharbi, Shahad A Alshehri, Wasayf A Almarwani, Khulud K Aljohani, Hanan M Hassan, Mohammed M H Al-Gayya. Echinacoside ameliorates hepatic fibrosis and tumor invasion in rats with thioacetamide-induced hepatocellular carcinoma. Biomolecules & biomedicine. 2024-03-10. PMID:38461536. |
the hepatic expression of mrna and protein levels of tgf-β1, β-catenin, smad4, matrix metalloproteinase-9 (mmp9), phosphoinositide 3-kinases (pi3k), mammalian target of rapamycin (mtor), connective tissue growth factor 2 (ccn2), e-cadherin, platelets derived growth factor (pdgf)-b and fascin were also analyzed. |
2024-03-10 |
2024-03-14 |
rat |
| Sepehr Zamani, Majid Salehi, Arian Ehterami, Mh Busra Fauzi, Ghasem Abbaszadeh-Goudarz. Assessing the efficacy of curcumin-loaded alginate hydrogel on skin wound healing: A gene expression analysis. Journal of biomaterials applications. 2024-03-07. PMID:38453252. |
furthermore, the treated group exhibited down-regulation of mmp9 gene expression, indicating a reduction in matrix degradation and inflammation. |
2024-03-07 |
2024-03-10 |
Not clear |
| Jiali Li, Yan Wu, Qi Yuan, Luxin Li, Wenqi Qin, Jia Jia, Kaiyuan Chen, Dan Wu, Xiaohuan Yua. Gelatin Microspheres Based on H8-Loaded Macrophage Membrane Vesicles to Promote Wound Healing in Diabetic Mice. ACS biomaterials science & engineering. 2024-03-07. PMID:38450619. |
the high expression of matrix metalloproteinase 9 (mmp9) and a high inflammatory response are indicative of poor diabetic wound healing. |
2024-03-07 |
2024-03-09 |
mouse |
| Kalyani Vemuri, Beatriz de Alves Pereira, Patricia Fuenzalida, Yelin Subashi, Stefano Barbera, Luuk van Hooren, Marie Hedlund, Fredrik Pontén, Cecilia Lindskog, Anna-Karin Olsson, Roberta Lugano, Anna Dimber. CD93 maintains endothelial barrier function and limits metastatic dissemination. JCI insight. 2024-03-05. PMID:38441970. |
primary melanoma growth was hampered in cd93-/- mice but metastatic dissemination was increased, associated with a disruption of adherens and tight junctions in tumor endothelial cells and elevated expression of matrix metalloprotease 9 (mmp9) at the metastatic site. |
2024-03-05 |
2024-03-08 |
mouse |
| Wei Fan, Hongping Chen, Meng Li, Xuehui Fan, Fangchao Jiang, Chen Xu, Yingju Wang, Wan Wei, Jihe Song, Di Zhong, Guozhong L. NRF2 activation ameliorates blood-brain barrier injury after cerebral ischemic stroke by regulating ferroptosis and inflammation. Scientific reports. vol 14. issue 1. 2024-03-04. PMID:38438409. |
similarly, sulforaphane (sfn) prevented the down-regulated tight junction proteins occludin and zonula occludens 1 (zo-1) and reduced the up-regulated aquaporin 4 (aqp4) and matrix metalloproteinase 9 (mmp9) after tmcao. |
2024-03-04 |
2024-03-07 |
mouse |
| Zhenhua Wang, Yuan Li, Zhixu Wang, Yuhui Liao, Qingqing Ye, Shilong Tang, Ting Wei, Pengyu Xiao, Juan Huang, Weitian L. Edaravone Maintains AQP4 Polarity Via OS/MMP9/β-DG Pathway in an Experimental Intracerebral Hemorrhage Mouse Model. Molecular neurobiology. 2024-02-29. PMID:38421470. |
edaravone or the specific inhibitor of matrix metalloproteinase 9 (mmp9), mmp9-in-1, called mmp9-inh was administered 10 min after ich via intraperitoneal injection. |
2024-02-29 |
2024-03-02 |
mouse |
| Samia Mahmoud Manawy, Eman Mohamed Faruk, Rabab Fawzy Hindawy, Mahmoud M Hassan, Diaa M G Farrag, Mansour A E Bashar, Hanan Fouad, Rania Abubaker Bagabir, Dina Allam Abdelmaksoud Hassan, Ahmed Mohammed Zaazaa, Mohamed Ghazy Attia Hablas, K Mostafa Kama. Modulation of the Sirtuin-1 signaling pathway in doxorubicin-induced nephrotoxicity (synergistic amelioration by resveratrol and pirfenidone). Tissue & cell. vol 87. 2024-02-27. PMID:38412579. |
renal tissue was collected to assess matrix metalloproteinase-9 (mmp9), inflammatory and apoptotic markers: tumor necrosis factor-alpha (tnf- β, caspase-3, cyclo-oxygenase-2 (cox-2), and oxidative stress markers: nitric oxide (no), glutathione (gsh), malondialdehyde (mda), and superoxide dismutase (sod). |
2024-02-27 |
2024-03-01 |
rat |
| Kuo-Wang Tsai, Yi-Fang Yang, Liang-Jen Wang, Chih-Chuan Pan, Cheng-Ho Chang, Yung-Chih Chiang, Tzu-Yun Wang, Ru-Band Lu, Sheng-Yu Le. Correlation of potential diagnostic biomarkers (circulating miRNA and protein) of bipolar II disorder. Journal of psychiatric research. vol 172. 2024-02-27. PMID:38412788. |
we previously identified certain peripheral biomarkers of bipolar ii disorder (bd-ii) including circulating mirnas (mir-7-5p, mir-142-3p, mir-221-5p, and mir-370-3p) and proteins (matrix metallopeptidase 9 (mmp9), phenylalanyl-trna synthetase subunit beta (farsb), peroxiredoxin 2 (prdx2), carbonic anhydrase 1 (ca-1), and proprotein convertase subtilisin/kexin type 9 (pcsk9)). |
2024-02-27 |
2024-03-01 |
Not clear |
| Jake Valeri, Charlotte Stiplosek, Sinead M O'Donovan, David Sinclair, Kathleen A Grant, Ratna Bollavarapu, Donna M Platt, Craig A Stockmeier, Barbara Gisabella, Harry Pantazopoulo. Extracellular matrix abnormalities in the hippocampus of subjects with substance use disorder. Translational psychiatry. vol 14. issue 1. 2024-02-24. PMID:38402197. |
we identified increased densities of pnns and cspg-labeled glial cells in sud, coinciding with decreased expression of the ecm protease matrix metalloproteinase 9 (mmp9), and increased expression for the excitatory synaptic marker vesicle associated membrane protein 2 (vamp2). |
2024-02-24 |
2024-02-27 |
human |
| Octavio Canales-Alvarez, Maria Margarita Canales-Martinez, Pilar Dominguez-Verano, Daniela Balderas-Cordero, Eduardo Madrigal-Bujaidar, Isela Álvarez-González, Marco Aurelio Rodriguez-Monro. Effect of Mexican Propolis on Wound Healing in a Murine Model of Diabetes Mellitus. International journal of molecular sciences. vol 25. issue 4. 2024-02-24. PMID:38396882. |
a histological analysis of the wounds was performed using h&e staining, and when matrix metalloproteinase 9 (mmp9) and α-actin were quantified by immunohistochemistry, cheep was shown to be associated with improved histological healing, as indicated by the reduced mmp9 and α-actin expression. |
2024-02-24 |
2024-02-26 |
mouse |
| Wenbin Xu, Han Yao, Zhen Wu, Xiaojun Yan, Zishan Jiao, Yajing Liu, Meng Zhang, Donglai Wan. Oncoprotein SET-associated transcription factor ZBTB11 triggers lung cancer metastasis. Nature communications. vol 15. issue 1. 2024-02-15. PMID:38355937. |
set interacts and collaborates with zbtb11 to promote lung cancer cell migration and invasion, primarily through set-zbtb11 complex-mediated transcriptional activation of matrix metalloproteinase-9 (mmp9). |
2024-02-15 |
2024-02-17 |
mouse |
| Lindsay E Rexrode, Joshua Hartley, Kurt C Showmaker, Lavanya Challagundla, Michael W Vandewege, Brigitte E Martin, Estelle Blair, Ratna Bollavarapu, Rhenius B Antonyraj, Keauna Hilton, Alex Gardiner, Jake Valeri, Barbara Gisabella, Michael R Garrett, Theoharis C Theoharides, Harry Pantazopoulo. Molecular profiling of the hippocampus of children with autism spectrum disorder. Molecular psychiatry. 2024-02-14. PMID:38355786. |
we observed decreased expression of synaptic proteins psd95 (p < 0.02) and syn1 (p < 0.02), increased expression of the extracellular matrix (ecm) protease mmp9 (p < 0.03), and decreased expression of mef2c (p < 0.03). |
2024-02-14 |
2024-02-17 |
mouse |