| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mahak Gupta, Shubhang Arya, Poonam Agrawal, Himanshu Gupta, Ruhi Sikk. Unravelling the molecular tapestry of pterygium: insights into genes for diagnostic and therapeutic innovations. Eye (London, England). 2024-06-21. PMID:38907016. |
matrix metalloproteinases (mmps), especially mmp2 and mmp9, contribute to ecm remodelling and angiogenesis in pterygium. |
2024-06-21 |
2024-06-24 |
Not clear |
| Han T N Nguyen, Bailey H Duhon, Hsuan-Chih Kuo, Melanie Fisher, Olivia M Brickey, Lisa Zhang, Jose J Otero, Daniel M Prevedello, Oliver F Adunka, Yin Re. Matrix metalloproteinase 9: An emerging biomarker for classification of adherent vestibular schwannoma. Neuro-oncology advances. vol 6. issue 1. 2024-06-19. PMID:38887507. |
we evaluate the role of matrix metalloproteinase 9 (mmp9) in vs and explore its potential as a biomarker to classify adherent vs. |
2024-06-19 |
2024-06-21 |
Not clear |
| Kuo Zhang, Zhi-Chao Wang, Hongxue Sun, Huimin Long, Yingju Wan. Esculentoside H reduces the PANoptosis and protects the blood-brain barrier after cerebral ischemia/reperfusion through the TLE1/PI3K/AKT signaling pathway. Experimental neurology. 2024-06-10. PMID:38857750. |
matrix metalloproteinases 9 (mmp9) plays a role in the destruction of blood-brain barrier (bbb) and cell death after cerebral ischemic/reperfusion (i/r). |
2024-06-10 |
2024-06-14 |
Not clear |
| Xiangqi Zhang, Wei Yu, Yihui Zhang, Wenkai Zhang, Jiayu Wang, Muge Gu, Sulin Cheng, Guogang Ren, Bo Zhao, Wei-En Yua. A hydrogen generator composed of poly (lactic-co-glycolic acid) nanofibre membrane loaded iron nanoparticles for infectious diabetic wound repair. Journal of colloid and interface science. vol 672. 2024-06-06. PMID:38843679. |
we also discovered that hydrogen can ameliorate fibroblast migration disorders by reducing the levels of matrix metalloproteinase 9 (mmp9). |
2024-06-06 |
2024-06-10 |
Not clear |
| Jinfang Luo, Yi Zhu, Yang Yu, Yujie Chen, Kang He, Jianxin Li. Sinomenine treats rheumatoid arthritis by inhibiting MMP9 and inflammatory cytokines expression: bioinformatics analysis and experimental validation. Scientific reports. vol 14. issue 1. 2024-06-04. PMID:38834626. |
the matrix metalloproteinase 9 (mmp9) was identified as the hub m1 macrophages-related biomarker in ra using bioinformatic analysis and molecular docking. |
2024-06-04 |
2024-06-07 |
Not clear |
| T L Reeder, D S Zarlenga, A L Zeigler, R M Dye. Transcriptional responses consistent with perturbation in dermo-epidermal homeostasis in septic sole ulceration. Journal of dairy science. 2024-06-02. PMID:38825108. |
these changes were accompanied by upregulation of pro-inflammatory transcripts interleukin 1 α (il1a), interleukin1 β (il1b), interleukin 1 receptor 1 (il1r1), inducible nitric oxide synthase (nos2), the inflammasome components nod like receptor protein 3 (nlrp3), pyrin and caspase recruitment domain (pycard), and caspase-1 interleukin converting enzyme (caspase), the matrix metalloproteinases (mmp2 and mmp9), and anti-inflammatory genes interleukin 1 receptor antagonist (il1rn) and interleukin1 receptor 2 (il1r2). |
2024-06-02 |
2024-06-05 |
cattle |
| Meng Zhang, Fenghua Zhao, Yuxuan Zhu, Linda A Brouwer, Hasse Van der Veen, Janette K Burgess, Martin C Harmse. Physical Properties and Biochemical Composition of Extracellular Matrix-Derived Hydrogels Dictate Vascularization Potential in an Organ-Dependent Fashion. ACS applied materials & interfaces. 2024-05-31. PMID:38819955. |
furthermore, cellular ecm remodeling responses varied with skin ecm hydrogels promoting matrix metalloproteinase 1 (mmp1) secretion, while hybrid ecm hydrogels exhibited increased mmp9, fibronectin, and collagen iv deposition. |
2024-05-31 |
2024-06-02 |
Not clear |
| Xiao-Juan Jiang, Ya-Dong Wang, Juan Sun, Ke-Long Ma, Da-Qiang Wu, Jing Shao, Tian-Ming Wang, Chang-Zhong Wan. [Mechanism of n-butanol extract of Pulsatilla Decoction in treating ulcerative colitis by activating BMP signaling pathway]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 7. 2024-05-30. PMID:38812188. |
alcian blue/periodic acid-schiff(ab/pas) staining was used to detect the number and mucus secretion status of goblet cells; immunohistochemistry was performed to measure the expression of ki67, cleaved caspase-3, mucin 2(muc2), and matrix metalloproteinase-9(mmp9) in colon tissues; and immunofluorescence was used to analyze the expression of tight junction proteins in colon tissues, and enzyme linked immunosorbent assay(elisa) was employed to quantify the levels of tumor necrosis factor-α(tnf-α), interleukin(il)-1β, and il-6. |
2024-05-30 |
2024-06-17 |
mouse |
| Dan Ma, Yongting Lu, Hong Ye, Chunyan Li, Jie Zhang, Tian Hao Bao, Jianhong Ha. miR-4685-3p Alleviates Human Brain Microvascular Endothelial Cells Injury by Regulating MMP9. Annals of clinical and laboratory science. vol 54. issue 2. 2024-05-27. PMID:38802152. |
the primary objective of this study is to investigate the potential role of mir-4685-3p and underlying mechanisms by which mir-4685-3p modulates matrix metalloproteinase-9 (mmp9) in cerebral microvascular endothelial cell injury. |
2024-05-27 |
2024-06-01 |
human |
| Yun Hu, Xu-Dong Hu, Zi-Qing He, Yang Liu, Yong-Kang Gui, Si-Hui Zhu, Xin Da, Yi-Nuo Liu, Li-Xia Liu, Qi-Ying Shen, Guang-Hong X. Anesthesia/surgery activate MMP9 leading to blood-brain barrier disruption, triggering neuroinflammation and POD-like behavior in aged mice. International immunopharmacology. vol 135. 2024-05-26. PMID:38796964. |
anesthesia and surgery activate matrix metalloproteinase 9 (mmp9), leading to blood-brain barrier (bbb) disruption and postoperative delirium (pod)-like behavior, especially in the elderly. |
2024-05-26 |
2024-05-31 |
mouse |
| Qiong Zhou, Geng Chen. Ampelopsin facilitates diabetic wound healing and keratinocyte cell progression by inhibiting the NLRP3 inflammasome pathway in macrophages. General physiology and biophysics. vol 43. issue 3. 2024-05-22. PMID:38774919. |
amp notably facilitated platelet endothelial cell adhesion molecule-31 (cd31), collagen type i alpha 1 chain (col1a1), and alpha-smooth muscle actin (α-sma), and inhibited matrix metallopeptidase 9 (mmp9) and cyclooxygenase 2 (cox2) expression in diabetic wounds. |
2024-05-22 |
2024-05-27 |
mouse |
| Sheereen Gull, Fareeda Tasneem, Ishtiaq Ahmed, Muhammad Aamir Aslam, Asima Tayyeb, Luqman Abid, Muhammad Imran Arshad, Naveed Shahza. Ethanolic extract of Euphorbia royleana Boiss. reduces metastasis of breast cancer cells and inhibits tumor progression in vivo. Medical oncology (Northwood, London, England). vol 41. issue 6. 2024-05-14. PMID:38743193. |
the expression of mesenchymal (e-cadherin and n-cadherin), matrix metalloproteinases (mmp2, mmp9), and stemness markers (oct3) were down-regulated by era. |
2024-05-14 |
2024-05-27 |
mouse |
| Jingxuan Zhang, Ying Han, Ruhan Jia, Qinfang Zhu, Xiaozhou Wang, Meiheng Liu, Wei Zhan. Exploring the role of myeloperoxidase in the atherosclerotic process in hypoxic mice based on the MAPK signaling pathway. Biochemical pharmacology. vol 225. 2024-05-12. PMID:38729447. |
in addition, hypoxia further exacerbates plaque instability by activating the mapk signaling pathway to upregulate vascular endothelial growth factor (vegf) and matrix metalloproteinase-9 (mmp9), which in turn promotes angiogenesis within the plaque. |
2024-05-12 |
2024-05-27 |
mouse |
| Kaiping Deng, Xiaodan Li, Zhipeng Liu, Yalong Su, Xuan Sun, Wurilege Wei, Yixuan Fan, Yanli Zhang, Feng Wan. IGF2BP2 regulates the proliferation and migration of endometrial stromal cells through the PI3K/AKT/mTOR signaling pathway in Hu sheep. Journal of animal science. 2024-05-10. PMID:38727196. |
additionally, the knockdown of igf2bp2 significantly increased the expression of matrix metalloprotein 9 (mmp9), vascular endothelial growth factor (vegf), and prolactin (prl) in escs. |
2024-05-10 |
2024-05-27 |
Not clear |
| Weizhong Qi, Li Jin, Shiqian Huang, Alafate Aikebaier, Song Xue, QianYi Wang, Qiyue Chen, Yao Lu, Changhai Din. Modulating Synovial Macrophage Pyroptosis and Mitophagy Interactions to Mitigate Osteoarthritis Progression using Functionalized Nanoparticles. Acta biomaterialia. 2024-05-10. PMID:38729544. |
in this study, we noted that synovial macrophages can activate pyroptosis in a gasdermin d-dependent manner and produce reactive oxygen species (ros), aberrantly activating the mammalian target of rapamycin complex 1 (mtorc1) pathway and matrix metalloproteinase-9 (mmp9) expression in synovial tissue samples collected from both patients with oa and collagen-induced osteoarthritis (cioa) mouse model. |
2024-05-10 |
2024-05-27 |
mouse |
| Grace H Curtis, Robyn E Reeve, Erica J Cresp. Leptin signaling promotes blood vessel formation in the Xenopus tail during the embryo-larval transition. Developmental biology. 2024-05-05. PMID:38705558. |
reduced leptin signaling lowered mrna expression of cenpk, gpx1, and mmp9, markers for cell proliferation, antioxidation, and extracellular matrix remodeling/cell migration, respectively, in the developing tail, providing insight into three possible mechanisms underlying leptin's promotion of angiogenesis. |
2024-05-05 |
2024-05-08 |
xenopus_laevis |
| Jie Zhou, Chau Q Le, Yun Zhang, James A Well. A general approach for selection of epitope-directed binders to proteins. Proceedings of the National Academy of Sciences of the United States of America. vol 121. issue 19. 2024-04-29. PMID:38683990. |
we generated antibodies that recognize the junction between the pro- and catalytic domains for three different matrix metalloproteases (mmps), mmp1, mmp3, and mmp9, that selectively block activation of each of these enzymes and impair cell migration. |
2024-04-29 |
2024-05-03 |
Not clear |
| Huixian Huang, Jia Huang, Wensi Lu, Yanjun Huang, Ran Luo, Luqman Bathalian, Ming Chen, Xuemin Wan. A Four-Week High-Fat Diet Induces Anxiolytic-like Behaviors through Mature BDNF in the mPFC of Mice. Brain sciences. vol 14. issue 4. 2024-04-27. PMID:38672038. |
furthermore, mrna levels of the n6-methyladenosine (m6a) demethylase, fat mass and obesity-associated protein (fto), and the hydrolase matrix metalloproteinase-9 (mmp9), also increased in the mpfc. |
2024-04-27 |
2024-04-29 |
mouse |
| Bingli Liu, Liping Su, Sze Jie Loo, Yu Gao, Ester Khin, Xiaocen Kong, Rinkoo Dalan, Xiaofei Su, Kok-Onn Lee, Jianhua Ma, Lei Y. Matrix metallopeptidase 9 contributes to the beginning of plaque and is a potential biomarker for the early identification of atherosclerosis in asymptomatic patients with diabetes. Frontiers in endocrinology. vol 15. 2024-04-25. PMID:38660518. |
to determine the roles of matrix metallopeptidase-9 (mmp9) on human coronary artery smooth muscle cells (hcasmcs) |
2024-04-25 |
2024-04-28 |
human |
| Marta Halasa, Ahmed Uosef, Henry V Ubelaker, Arijita Subuddhi, Krupa R Mysore, Jacek Z Kubiak, Rafik M Ghobrial, Jarek Wosik, Malgorzata Klo. Gadolinium retention effect on macrophages - a potential cause of MRI contrast agent Dotarem toxicity. Cell and tissue research. 2024-04-16. PMID:38625373. |
gadolinium retention for 7 days decreased macrophage adhesion and motility and dysregulated the expression of adhesion and fibrotic pathway-related proteins such as notch1 and its ligand jagged1, adhesion/migration-related proteins pak1 and shp1, immune response-related transcription factors smad3 and tcf19, and chemokines cxcl10 and cxcl13, and dysregulated the mrna expression of fibrosis-related genes involved in extracellular matrix (ecm) synthesis, such as col6a1, fibronectin, mmp9, and mmp12. |
2024-04-16 |
2024-04-18 |
Not clear |