| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sonjid Ochirbat, Tzu-Chun Kan, Chun-Chun Hsu, Tzu-Hsuan Huang, Kuo-Hsiang Chuang, Michael Chen, Chun-Chia Cheng, Chun-Chao Chang, Sri Rahayu, Jungshan Chan. The angiogenic role of the alpha 9-nicotinic acetylcholine receptor in triple-negative breast cancers. Angiogenesis. 2024-08-23. PMID:39177676. |
to unbraid the molecular mechanism of α9-nachr in nicotine-mediated angiogenesis, the α9 bsabs were applied and revealed the inhibitory roles in nicotine-induced production of hypoxia-inducible factor-2 alpha (hif-2α), vascular endothelial growth factor a (vegf-a), phosphorylated vascular endothelial growth factor receptor 2 (p-vegfr2), vascular endothelial growth factor receptor 2 (vegfr2) and matrix metalloproteinase-9 (mmp9) from triple-negative breast cancer cells (mda-mb-231), suggesting α9-nachrs played an important role in nicotine-induced angiogenesis. |
2024-08-23 |
2024-08-25 |
Not clear |
| Zhao Liu, Nan Zhao, Ling Liang, Menggeng Li, Xin Nie, Yuan Wang, Qin Liu, Qi Zhou, Peng Sh. Evaluation of the anti-aging potential of acetyl tripeptide-30 citrulline in cosmetics. International journal of pharmaceutics. 2024-08-05. PMID:39103061. |
moreover, acetyl tripeptide-30 citrulline specifically up-regulates collagen iv and down-regulates matrix metalloproteinase-9 (mmp9), enhances the expression of skin barrier proteins transglutaminase 1 (tgm1) and filaggrin (flg), thereby demonstrating its reparative capabilities. |
2024-08-05 |
2024-08-08 |
mouse |
| Mysore Keshavmurthy Phanish, Felicia Heidebrecht, Michaela Jackson, Frank Rigo, Mark Edward Carl Dockrel. TARGETING ALTERNATIVE SPLICING OF FIBRONECTIN IN HUMAN RENAL PROXIMAL TUBULE EPITHELIAL CELLS WITH ANTISENSE OLIGONUCLEOTIDES TO REDUCE EDA+ FIBRONECTIN PRODUCTION AND BLOCK AN AUTOCRINE LOOP THAT DRIVES RENAL FIBROSIS. Experimental cell research. 2024-08-04. PMID:39098465. |
the efficacy of aso to block eda exon inclusion was assessed by eda+ fibronectin rna and protein expression; the expression of tgfβ, αsma (α smooth muscle actin), mmp2 (matrix metalloproteinse-2), mmp9 (matrix metalloproteinse-9), collagen i, k cadherin and connexin 43 was analysed. |
2024-08-04 |
2024-08-07 |
human |
| Yan Liu, Hongzhao Qi, Jinbao Zong, Min Li, Yanyan Yang, Xiaolu Li, Tianxiang Li, Jae Youl Cho, Tao Y. Oral Piwi-Interacting RNA Delivery Mediated by Green Tea-Derived Exosome-Like Nanovesicles for the Treatment of Aortic Dissection. Advanced healthcare materials. 2024-08-01. PMID:39087398. |
this study demonstrates that an antagomir targeting heart-apoptosis-associated pirna (haapir) effectively regulates vascular remodeling, mitigating ad occurrence and progression through the myocyte enhancer factor 2d (mef2d) and matrix metallopeptidase 9 (mmp9) pathways. |
2024-08-01 |
2024-08-03 |
mouse |
| Tasuku Ohno, Takeshi Kikuchi, Yuki Suzuki, Ryoma Goto, Daiki Takeuchi, Jun-Ichiro Hayashi, Eisaku Nishida, Genta Yamamoto, Shun Kondo, Kouta Ono, Shuji Nomoto, Akio Mitan. Periodontitis promotes hepatocellular carcinoma in Stelic Animal model (STAM) mice. Scientific reports. vol 14. issue 1. 2024-07-30. PMID:39080409. |
tumor necrosis factor-α (tnfα), matrix metalloproteinase-9 (mmp9), collagen 1, and angiopoietin-like protein 2 (angptl2) gene expression was significantly increased in the liver of the periodontitis group. |
2024-07-30 |
2024-08-02 |
mouse |
| Yaqi Chen, Xianglong Zheng, Wenrui Shi, Chenghui Lu, Yu Qiu, Lisong Li. Osteoblasts are induced into cancer-associated osteoblasts to promote tumor progression in head and neck squamous cell carcinoma. Biochimica et biophysica acta. Molecular basis of disease. 2024-07-29. PMID:39074625. |
through transcriptome analysis, we identified three genes-osteopontin (spp1), chemokine (c-x-c motif) ligand 1 (cxcl1), and matrix metalloprotein (mmp)9 (mmp9) linked to a poorer prognosis. |
2024-07-29 |
2024-08-02 |
Not clear |
| Guiying Pang, Ling Ye, Yinxiao Jiang, Yilin Wu, Rufeng Zhang, Hongxu Yang, Yi Yan. Unveiling the bidirectional role of MMP9: A key player in kidney injury. Cellular signalling. 2024-07-29. PMID:39074714. |
mmp9, a member of the mmps family, is categorized as a constituent of the gelatinase b subgroup, and its involvement in extracellular matrix (ecm) remodeling and renal fibrosis highlights its importance in the development and progression of renal diseases. |
2024-07-29 |
2024-08-02 |
Not clear |
| Liu-Yan Chen, Chuan-Mei Wu, Pan Liang, Jin-Feng Wei, Ting-Ting Lan, Min Guo, Yong-Hua Li, Mei R. [Anti-inflammatory effect and its mechanism of Saracae Cortex based on zebrafish model and network pharmacology]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 11. 2024-07-23. PMID:39041167. |
protein-protein interaction(ppi) analysis showed that saracae cortex mainly acted on signal transducer and activator of transcription 3(stat3), vascular endothelial growth factor a( vegfa), epidermal growth factor( egf), tumor necrosis factor( tnf),tumor protein p53(tp53), matrix metalloprotein 9(mmp9), c-fos proto-oncogene protein(fos), estrogen receptor 1(esr1), cx-c motif chemokine ligand 8(cxcl8), cluster of differentiation 8(cd8), and other targets. |
2024-07-23 |
2024-07-25 |
zebrafish |
| V I Konenkov, V V Nimaev, A V Shevchenko, V F Prokofie. Polymorphism of angiogenesis regulation factor genes (VEGF/VEGFR), and extracellular matrix remodeling genes (MMP/TIMP), and the levels of their products in extracellular tissues of patients with primary and secondary lymphedema. Vavilovskii zhurnal genetiki i selektsii. vol 28. issue 4. 2024-07-19. PMID:39027126. |
polymorphism of vegf (rs699947, rs3025039), kdr (rs10020464, rs11133360), nrp2 (rs849530, rs849563, rs16837641), matrix metalloproteinases mmp2 (rs2438650), mmp3 (rs3025058), mmp9 (rs3918242), timp1 (rs6609533) and their combinations were analyzed by the restriction fragment length polymorphism method and taqman rt-pcr. |
2024-07-19 |
2024-07-21 |
Not clear |
| Thi Hoa Pham, Nguyen Minh Trang, Eun-Nam Kim, Hye Gwang Jeong, Gil-Saeng Jeon. Citropten Inhibits Vascular Smooth Muscle Cell Proliferation and Migration via the TRPV1 Receptor. ACS omega. vol 9. issue 27. 2024-07-16. PMID:39005766. |
also, citropten inhibited the expression of proliferation-related proteins, including proliferating cell nuclear antigen (pcna), cyclin e1, cyclin d1, and migration-related markers such as matrix metalloproteinase (mmp), mmp2 and mmp9, in a concentration-dependent manner. |
2024-07-16 |
2024-07-18 |
rat |
| Haissa O Brito, Renata C Reis, Israel Bini, Daniel Wilhelms, David Engblom, Rui M Gil da Costa, Luciane O Brito, Maria do Desterro S B Nascimento, Marcelo Souza de Andrade, Aleksander R Zampronio, Célia C Cavichioll. NK1 receptor mediates cerebral cellular and extracellular morphological changes during the LPS-induced febrile response. Brain research. 2024-07-08. PMID:38977236. |
the expression of matrix metalloproteinase 9 (mmp9) was studied using confocal microscopy. |
2024-07-08 |
2024-07-12 |
rat |
| Xiaohua Zhou, Fuping Gao, Guangqi Xu, Yongqiang Puyang, Hongqing Rui, Junsheng L. SIAH1 facilitates the migration and invasion of gastric cancer cells through promoting the ubiquitination and degradation of RECK. Heliyon. vol 10. issue 11. 2024-07-04. PMID:38961977. |
in addition, silencing of siah1 significantly inhibited the migration and invasion of gastric cancer cells through inhibiting the expression of matrix metalloproteinase-9 (mmp9), while overexpression of siah1 had the opposite effect. |
2024-07-04 |
2024-07-10 |
human |
| Zijun Wu, Yuan Yang, Maojuan Chen, Yunfei Zh. Matrix metalloproteinase 9 expression and glioblastoma survival prediction using machine learning on digital pathological images. Scientific reports. vol 14. issue 1. 2024-07-03. PMID:38956384. |
this study aimed to apply pathomics to predict matrix metalloproteinase 9 (mmp9) expression in glioblastoma (gbm) and investigate the underlying molecular mechanisms associated with pathomics. |
2024-07-03 |
2024-07-06 |
Not clear |
| Haofei Wang, Yan Liu, Sujuan Xu, Tao Wang, Xiaojun Chen, Huiyang Jia, Qi Dong, Heng Zhang, Shuai Wang, Huijie Ma, Zhiyong Ho. Proteomics analysis of deep fascia in acute compartment syndrome. PloS one. vol 19. issue 7. 2024-07-01. PMID:38950026. |
compared with the con group, the expression of peroxidasin homolog (pxdn), which promotes the function of fibroblasts, and leukocyte differentiation antigen 74 (cd74), which enhances the proliferation of fibroblasts, were significantly upregulated (p all <0.05), while the expression of matrix metalloproteinase-9 (mmp9), which is involved in collagen hydrolysis, and neutrophil elastase (elane), which is involved in elastin hydrolysis, were significantly reduced in the tb group (p all <0.05), indicating fascia tissue underwent microenvironment reconstruction during acs. |
2024-07-01 |
2024-07-04 |
Not clear |
| Kuan Feng, Gengfan Ye, Hongcai Wang, Shiwei Li, Xuebin Wen, Maosong Che. Research on the mechanism of TWSG1 in the malignant progression of glioma cells and tumor-associated macrophage infiltration. Journal of neuropathology and experimental neurology. 2024-07-01. PMID:38950414. |
it also reduced the expression of the matrix metalloproteinases mmp2 and mmp9 both in vivo and in vitro. |
2024-07-01 |
2024-07-04 |
mouse |
| Lorelei Hughes, Larry V Lopez, Mary Kearns-Jonke. Prostaglandin E2 induces YAP1 and Agrin through EP4 in Neonatally-Derived Islet-1+ Stem Cells. Stem cells and development. 2024-06-29. PMID:38943285. |
pge2 administration further elevated the expression of stemness markers and the matrix metalloproteinase mmp9, a key regulator of remodeling in the extracellular matrix post injury. |
2024-06-29 |
2024-07-02 |
Not clear |
| Eman Maher Zahran, Miada F Abdelwahab, Reham Hassan Mohyeldin, Omar Y Tammam, Nehad M Reda Abdel-Maqsoud, Faisal H Altemani, Naseh A Algehainy, Mohammed A Alanazi, Mohammed M Jalal, Mahmoud A Elrehany, Gerhard Bringmann, Usama Ramadan Abdelmohse. Combination of Callyspongia sp. and stem cells for wound repair and skin regeneration: in vivo and in silico evidences. Chemistry & biodiversity. 2024-06-28. PMID:38941178. |
additionally, in silico modeling was particularly targeting matrix metalloproteinase-9 (mmp9), a key player in wound healing processes. |
2024-06-28 |
2024-07-01 |
rat |
| Onurcan Sezginer, Nese Unve. Dissection of pro-tumoral macrophage subtypes and immunosuppressive cells participating in M2 polarization. Inflammation research : official journal of the European Histamine Research Society ... [et al.]. 2024-06-27. PMID:38935134. |
the majority of m2 subtypes are anti-inflammatory and pro-angiogenic, secreting growth factors (vegf, pdgf) and matrix metalloproteinases (mmp2, mmp9) which boost tumor growth, metastasis, and invasion. |
2024-06-27 |
2024-06-29 |
Not clear |
| Tetsuro Kamiya, Nagisa Mizuno, Kaho Hayashi, Tomohiro Otsuka, Manami Haba, Naohito Abe, Masayoshi Oyama, Hirokazu Har. Methoxylated Flavones from Journal of agricultural and food chemistry. 2024-06-24. PMID:38910321. |
methoxylated flavones from matrix metalloproteinase 9 (mmp9), an mmp isozyme, plays a crucial role in tumor progression by degrading basement membranes. |
2024-06-24 |
2024-06-26 |
Not clear |
| Zhiqin Fan, Fei Chen, Yingmin Liu, Xiaotong Huang, Siyue Tian, Yuqing M. Expression and Clinicopathological Significance of Extracellular Matrix Remodeling Markers in Esophageal Squamous Carcinoma. Critical reviews in eukaryotic gene expression. vol 34. issue 6. 2024-06-24. PMID:38912964. |
the results suggested that extracellular matrix remodeling markers (integrin αv, fibronectin, mmp9) were abnormally highly expressed in esophageal squamous carcinoma tissues. |
2024-06-24 |
2024-06-26 |
Not clear |