| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiang-You Hu, Huai-Yu Zhang, Song Qin, Hao Xu, Dick F Swaab, Jiang-Ning Zho. Increased p75(NTR) expression in hippocampal neurons containing hyperphosphorylated tau in Alzheimer patients. Experimental neurology. vol 178. issue 1. 2003-01-08. PMID:12460612. |
increased p75(ntr) expression in hippocampal neurons containing hyperphosphorylated tau in alzheimer patients. |
2003-01-08 |
2023-08-12 |
Not clear |
| Xiang-You Hu, Huai-Yu Zhang, Song Qin, Hao Xu, Dick F Swaab, Jiang-Ning Zho. Increased p75(NTR) expression in hippocampal neurons containing hyperphosphorylated tau in Alzheimer patients. Experimental neurology. vol 178. issue 1. 2003-01-08. PMID:12460612. |
the aim of present study was to detect the relationship between p75(ntr)-containing neurons and the pretangles consisting of hyperphosphorylated tau stained by alz-50 in the hippocampus of ad patients. |
2003-01-08 |
2023-08-12 |
Not clear |
| Andrea Reyna-Neyra, Ignacio Camacho-Arroyo, Patricia Ferrera, Clorinda Aria. Estradiol and progesterone modify microtubule associated protein 2 content in the rat hippocampus. Brain research bulletin. vol 58. issue 6. 2002-12-23. PMID:12372566. |
because these processes involve changes in cytoskeleton organization, we studied the effects of e(2) and p(4) in the expression of two cytoskeletal proteins: microtubule associated protein 2 (map2) and tau in the hippocampus and the frontal cortex of ovariectomized adult rats. |
2002-12-23 |
2023-08-12 |
rat |
| Andrea Reyna-Neyra, Ignacio Camacho-Arroyo, Patricia Ferrera, Clorinda Aria. Estradiol and progesterone modify microtubule associated protein 2 content in the rat hippocampus. Brain research bulletin. vol 58. issue 6. 2002-12-23. PMID:12372566. |
while tau expression was unaffected by e(2) and p(4), an increase in map2 protein content in the hippocampus but not in the cortex was observed after e(2) and p(4) treatments. |
2002-12-23 |
2023-08-12 |
rat |
| Max Holzer, Ulrich Gärtner, Andrea Stöbe, Wolfgang Härtig, Hildegard Gruschka, Martina K Brückner, Thomas Arend. Inverse association of Pin1 and tau accumulation in Alzheimer's disease hippocampus. Acta neuropathologica. vol 104. issue 5. 2002-12-23. PMID:12410395. |
inverse association of pin1 and tau accumulation in alzheimer's disease hippocampus. |
2002-12-23 |
2023-08-12 |
Not clear |
| Noriko Takayama, Eizo Iseki, Takayuki Yamamoto, Kenji Kosak. Regional quantitative study of formation process of neurofibrillary tangles in the hippocampus of non-demented elderly brains: comparison with late-onset Alzheimer's disease brains. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 22. issue 3. 2002-12-20. PMID:12416553. |
in addition, the distribution pattern of tau-positive neurons in the hippocampus was closely related to degeneration of the perforant pathway with the accumulation of tau. |
2002-12-20 |
2023-08-12 |
Not clear |
| A Takashim. [Analysis of mouse model exhibiting neurofibrillary changes]. Rinsho shinkeigaku = Clinical neurology. vol 41. issue 12. 2002-11-08. PMID:12235811. |
in the present study, neurons of hippocampus and cerebral cortex in our tg mice showed phosphorylated and ubiquitinated tau aggregations with a beta-sheet structure. |
2002-11-08 |
2023-08-12 |
mouse |
| Victoria Zhukareva, Keyur Shah, Kunihiro Uryu, Heiko Braak, Kelly Del Tredici, Sonali Sundarraj, Christopher Clark, John Q Trojanowski, Virginia M-Y Le. Biochemical analysis of tau proteins in argyrophilic grain disease, Alzheimer's disease, and Pick's disease : a comparative study. The American journal of pathology. vol 161. issue 4. 2002-11-05. PMID:12368187. |
analyses of separately dissected gray and white matter samples from various cortical regions revealed that pathological tau in argyrophilic grain disease was confined primarily to mediotemporal neocortical gray and adjacent white matter, and also to the allocortex, amygdala, and hippocampus. |
2002-11-05 |
2023-08-12 |
Not clear |
| Rika Dei, Akinori Takeda, Hisayoshi Niwa, Mei Li, Yuji Nakagomi, Masaki Watanabe, Toshiaki Inagaki, Yukihiko Washimi, Yoshinari Yasuda, Katsunori Horie, Toshio Miyata, Gen Sobu. Lipid peroxidation and advanced glycation end products in the brain in normal aging and in Alzheimer's disease. Acta neuropathologica. vol 104. issue 2. 2002-10-22. PMID:12111353. |
in ad cases, mda was colocalized with tau protein in ca2 hippocampal neurons; such colocalization was rare in ca1. |
2002-10-22 |
2023-08-12 |
human |
| Quanbao Wang, Jianzhi Wan. Injection of bradykinin or cyclosporine A to hippocampus induces Alzheimer-like phosphorylation of Tau and abnormal behavior in rats. Chinese medical journal. vol 115. issue 6. 2002-08-13. PMID:12123558. |
injection of bradykinin or cyclosporine a to hippocampus induces alzheimer-like phosphorylation of tau and abnormal behavior in rats. |
2002-08-13 |
2023-08-12 |
rat |
| Luigia Trabace, Tommaso Cassano, Antonia Loverre, Luca Steardo, Vincenzo Cuom. CHF2819: pharmacological profile of a novel acetylcholinesterase inhibitor. CNS drug reviews. vol 8. issue 1. 2002-08-09. PMID:12070526. |
by oral administration to young adult rats chf2819 did not affect extracellular hippocampal levels of glutamate (glu), aspartate (asp), gamma-aminobutyric acid (gaba), taurine (tau), arginine (arg) or citrulline (cit). |
2002-08-09 |
2023-08-12 |
rat |
| Victoria Zhukareva, David Mann, Stuart Pickering-Brown, Kunihiro Uryu, Theresa Shuck, Keyur Shah, Murray Grossman, Bruce L Miller, Christine M Hulette, Stuart C Feinstein, John Q Trojanowski, Virginia M-Y Le. Sporadic Pick's disease: a tauopathy characterized by a spectrum of pathological tau isoforms in gray and white matter. Annals of neurology. vol 51. issue 6. 2002-08-09. PMID:12112079. |
therefore, pick's disease is characterized by an accumulations of pick bodies in the hippocampal region and cortex as well as the presence of three and four microtubule-binding repeat tau pathology in both cortical gray and white matter that distinguish this tauopathy from other neurodegenerative disorders. |
2002-08-09 |
2023-08-12 |
Not clear |
| R Sinigaglia-Coimbra, E A Cavalheiro, C G Coimbr. Postischemic hyperthermia induces Alzheimer-like pathology in the rat brain. Acta neuropathologica. vol 103. issue 5. 2002-06-21. PMID:11935259. |
associated immunohistochemical findings after 2 or 6 months of recovery included: (1) complement activation (membrane attack complex formation); (2) generalized overexpression of ubiquitin in surviving forebrain neurons; (3) persistent activation of macrophages; (4) presence of gemistocytic astrocytes in the hippocampus; (5) maturation of amyloid plaques (identified by immunohistochemistry using anti-human beta-a4 primary antibody) in cerebral cortex; and (6) intracellular deposits identified by anti-human hyperphosphorylated tau protein antibodies. |
2002-06-21 |
2023-08-12 |
human |
| Mark Rapoport, Hana N Dawson, Lester I Binder, Michael P Vitek, Adriana Ferreir. Tau is essential to beta -amyloid-induced neurotoxicity. Proceedings of the National Academy of Sciences of the United States of America. vol 99. issue 9. 2002-06-11. PMID:11959919. |
cultured hippocampal neurons obtained from wild-type, tau knockout, and human tau transgenic mice were treated with fibrillar abeta. |
2002-06-11 |
2023-08-12 |
mouse |
| Eizo Iseki, Noriko Takayama, Wami Marui, Kenji Uéda, Kenji Kosak. Relationship in the formation process between neurofibrillary tangles and Lewy bodies in the hippocampus of dementia with Lewy bodies brains. Journal of the neurological sciences. vol 195. issue 1. 2002-05-07. PMID:11867079. |
using tau immunohistochemistry and alpha-synuclein immunohistochemistry, we quantitatively investigated the most frequent sites and the formation process of neurofibrillary tangles (nft) and lewy bodies (lb) in the hippocampus from 20 patients with dementia with lewy bodies (dlb). |
2002-05-07 |
2023-08-12 |
Not clear |
| H C Baxter, W-G Liu, J L Forster, A Aitken, J R Frase. Immunolocalisation of 14-3-3 isoforms in normal and scrapie-infected murine brain. Neuroscience. vol 109. issue 1. 2002-04-11. PMID:11784696. |
the tau isoform was found only in the hippocampus and medulla, and the epsilon isoform was found throughout grey matter of the cns. |
2002-04-11 |
2023-08-12 |
Not clear |
| C González-Billault, M Engelke, E M Jiménez-Mateos, F Wandosell, A Cáceres, J Avil. Participation of structural microtubule-associated proteins (MAPs) in the development of neuronal polarity. Journal of neuroscience research. vol 67. issue 6. 2002-04-09. PMID:11891784. |
in this report we have characterized the effect of the combined suppression of map1b and tau, and map1b and map2 on neuronal polarization in cultured hippocampal cells grown on a laminin-containing substrate. |
2002-04-09 |
2023-08-12 |
mouse |
| Steven M Singer, Gina M Zainelli, Maryam A Norlund, John M Lee, Nancy A Mum. Transglutaminase bonds in neurofibrillary tangles and paired helical filament tau early in Alzheimer's disease. Neurochemistry international. vol 40. issue 1. 2002-03-06. PMID:11738469. |
in control cases with nft present in the entorhinal cortex and hippocampus, indicative of braak and braak stage ii, epsilon(gamma-glutamyl)lysine bonds were present in phf tau in parietal and frontal cortex, despite the lack of microscopically detectable nft or senile plaques in these cortical regions. |
2002-03-06 |
2023-08-12 |
Not clear |
| I K Takeuchi, Y K Takeuch. Transient accumulation of Gallyas-Braak-positive and phosphorylated tau-immunopositive substances in neuronal lipofuscin granules in the amygdala, hippocampus and entorhinal cortex of rats during long-term chloroquine intoxication. Acta neuropathologica. vol 102. issue 2. 2002-02-25. PMID:11563636. |
long-term chloroquine (cq) intoxication of normal and groggy mutant rats resulted in transient accumulation of gallyas-braak (g-b) -positive and phosphorylated tau (at8) -immunopositive substances in neuronal lipofuscin granules in the amygdala, hippocampus and entorhinal cortex. |
2002-02-25 |
2023-08-12 |
rat |
| Kentaro Tanemura, Miyuki Murayama, Takumi Akagi, Tsutomu Hashikawa, Takashi Tominaga, Michinori Ichikawa, Haruyasu Yamaguchi, Akihiko Takashim. Neurodegeneration with tau accumulation in a transgenic mouse expressing V337M human tau. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 1. 2002-02-04. PMID:11756496. |
v337m tg mice revealed tau aggregations in the hippocampus, which fulfills the histological criteria for nfts in human neurodegenerative diseases. |
2002-02-04 |
2023-08-12 |
mouse |