| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marco Pugliese, Joan Mascort, Nicole Mahy, Isidro Ferre. Diffuse beta-amyloid plaques and hyperphosphorylated tau are unrelated processes in aged dogs with behavioral deficits. Acta neuropathologica. vol 112. issue 2. 2007-02-01. PMID:16775693. |
single and double-labeling immunocytochemistry has been used to learn about the localization, distribution, and possible relationship between beta-amyloid protein (abeta) deposition and tau hyperphosphorylation in the canine cerebral cortex with age. |
2007-02-01 |
2023-08-12 |
dog |
| Buffie J Clodfelder-Miller, Anna A Zmijewska, Gail V W Johnson, Richard S Jop. Tau is hyperphosphorylated at multiple sites in mouse brain in vivo after streptozotocin-induced insulin deficiency. Diabetes. vol 55. issue 12. 2007-01-16. PMID:17130475. |
a massive (fivefold average increase) and widespread at multiple residues (detected with eight different phosphorylation-dependent tau antibodies) increase in the phosphorylation of tau was found in mouse cerebral cortex and hippocampus within 3 days of insulin depletion by streptozotocin treatment. |
2007-01-16 |
2023-08-12 |
mouse |
| Carla M Lema Tomé, Charles U Nottingham, Chelsey M Smith, Amanda S Beauchamp, Parkson W Leung, Christopher P Turne. Neonatal exposure to MK801 induces structural reorganization of the central nervous system. Neuroreport. vol 17. issue 8. 2006-08-31. PMID:16708014. |
within the somatosensory cortex, mk801 triggered robust, caspase-3-dependent apoptotic injury, reduced expression of cytoskeletal proteins map2 and tau, and increased synapse associated protein snap25. |
2006-08-31 |
2023-08-12 |
rat |
| Zhong-sen Qu, Qing Tian, Xin-wen Zhou, Qun Wang, Qi Zhang, Jian-zhi Wan. [Mechanism of tau hyperphosphorylation in brain cortex of diabetic rats and effect of LiCl]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. vol 28. issue 2. 2006-07-21. PMID:16733913. |
[mechanism of tau hyperphosphorylation in brain cortex of diabetic rats and effect of licl]. |
2006-07-21 |
2023-08-12 |
rat |
| Xu Li, Fen Lu, Jian-Zhi Wang, Cheng-Xin Gon. Concurrent alterations of O-GlcNAcylation and phosphorylation of tau in mouse brains during fasting. The European journal of neuroscience. vol 23. issue 8. 2006-07-13. PMID:16630055. |
the hippocampus was found more vulnerable to the tau alterations than the cerebral cortex, which is consistent with the fact that it is the hippocampus that is first affected in ad. |
2006-07-13 |
2023-08-12 |
mouse |
| Keith A Josephs, Omi Katsuse, Dayne A Beccano-Kelly, Wen-Lang Lin, Ryan J Uitti, Yasuhiro Fujino, Bradley F Boeve, Michael L Hutton, Matthew C Baker, Dennis W Dickso. Atypical progressive supranuclear palsy with corticospinal tract degeneration. Journal of neuropathology and experimental neurology. vol 65. issue 4. 2006-06-09. PMID:16691120. |
prominent tau pathology was found in oligodendrocytes in motor cortex, subjacent white matter, and corticospinal tract characterized by globular cytoplasmic filamentous inclusions that were immunoreactive for 4r tau. |
2006-06-09 |
2023-08-12 |
Not clear |
| Antonella Caccamo, Salvatore Oddo, Lauren M Billings, Kim N Green, Hilda Martinez-Coria, Abraham Fisher, Frank M LaFerl. M1 receptors play a central role in modulating AD-like pathology in transgenic mice. Neuron. vol 49. issue 5. 2006-05-09. PMID:16504943. |
the effect of af267b on cognition predicted the neuropathological outcome, as both the abeta and tau pathologies were reduced in the hippocampus and cortex, but not in the amygdala. |
2006-05-09 |
2023-08-12 |
mouse |
| Tong Li, Cheryl Hawkes, Hamid Y Qureshi, Satyabrata Kar, Hemant K Paude. Cyclin-dependent protein kinase 5 primes microtubule-associated protein tau site-specifically for glycogen synthase kinase 3beta. Biochemistry. vol 45. issue 10. 2006-05-03. PMID:16519508. |
we found that cdk5, gsk3beta, and tau are virtually colocalized in rat brain cortex. |
2006-05-03 |
2023-08-12 |
rat |
| Isidro Ferrer, Marta Barrachina, Berta Puig, M Martínez de Lagrán, Eulalia Martí, Jesús Avila, Mara Diersse. Constitutive Dyrk1A is abnormally expressed in Alzheimer disease, Down syndrome, Pick disease, and related transgenic models. Neurobiology of disease. vol 20. issue 2. 2006-01-23. PMID:16242644. |
transgenic mice bearing a triple tau mutation (g272v, p301l, and r406w) and expressing hyper-phosphoyrylated tau in neurons of the entorhinal cortex, hippocampus, and cerebral neocortex show increased expression of dyrk1a in individual neurons in the same regions. |
2006-01-23 |
2023-08-12 |
mouse |
| Yuko Saito, Yasufumi Motoyoshi, Takeshi Kashima, Naotaka Izumiyama-Shimomura, Tatsushi Toda, Imaharu Nakano, Masato Hasegawa, Shigeo Murayam. Unique tauopathy in Fukuyama-type congenital muscular dystrophy. Journal of neuropathology and experimental neurology. vol 64. issue 12. 2006-01-18. PMID:16319722. |
in fetal cases, the neuropil of malformed cerebral cortex was diffusely immunostained with anti-aberrantly phosphorylated tau antibodies. |
2006-01-18 |
2023-08-12 |
Not clear |
| Hideki Shimura, Hideo Mori, Yasuko Komatsuzaki, Kazuhiro Nakamura, Masashi Takanashi, Nobutaka Hattori, Yoshikuni Mizun. [A 54-year-old man with familial parkinsonism, gaze palsy, and dementia]. No to shinkei = Brain and nerve. vol 57. issue 12. 2006-01-17. PMID:16375198. |
immunohistochemistry using anti-tau antibodies revealed tau-positive neurons, glial cells and threads in the cerebral cortex, white matter and subcortical nuclei; these tau deposition reacted with an anti-4-repeat tau antibody, but not reacted to an anti-3-repeat tau antibody. |
2006-01-17 |
2023-08-12 |
human |
| Toshiki Uchihara, Kuniaki Tsuchiya, Ayako Nakamura, Haruhiko Akiyam. Argyrophilic grains are not always argyrophilic--distinction from neurofibrillary tangles of diffuse neurofibrillary tangles with calcification revealed by comparison between Gallyas and Campbell-Switzer methods. Acta neuropathologica. vol 110. issue 2. 2005-12-13. PMID:15971055. |
this staining profile of ags is identical with those of tau-positive structures in the cortex of progressive supranuclear palsy/corticobasal degeneration, both composed of 4r tau. |
2005-12-13 |
2023-08-12 |
Not clear |
| Jun Li, Gregor Dietsche, Diana Iftime, Sergey E Skipetrov, Georg Maret, Thomas Elbert, Brigitte Rockstroh, Thomas Gisle. Noninvasive detection of functional brain activity with near-infrared diffusing-wave spectroscopy. Journal of biomedical optics. vol 10. issue 4. 2005-12-07. PMID:16178636. |
from an analysis of the experimental data with an analytical theory for g(1)(r,tau) from a three-layer geometry with optical and dynamical heterogeneity representing scalp, skull, and cortex, we obtain quantitative estimates of the diffusion coefficient in cortical regions. |
2005-12-07 |
2023-08-12 |
human |
| J Y Zhang, S J Liu, H L Li, J-Z Wan. Microtubule-associated protein tau is a substrate of ATP/Mg(2+)-dependent proteasome protease system. Journal of neural transmission (Vienna, Austria : 1996). vol 112. issue 4. 2005-10-28. PMID:15372326. |
in the present study, we found that different forms of tau, including phosphorylated tau (phf-1) and non-phosphorylated tau (tau-1) as well as total tau (tau-5) in rat brain cortex extract, were degraded when it was co-incubated with atp and mgcl(2) at 33 degrees c in vitro, and non-phosphorylated tau at tau-1 epitope was more accessible to the atp/mg(2+)-depended proteolysis. |
2005-10-28 |
2023-08-12 |
rat |
| J Y Zhang, S J Liu, H L Li, J-Z Wan. Microtubule-associated protein tau is a substrate of ATP/Mg(2+)-dependent proteasome protease system. Journal of neural transmission (Vienna, Austria : 1996). vol 112. issue 4. 2005-10-28. PMID:15372326. |
hyperphosphorylated tau isolated from ad brain (ad p-tau) was also partially degraded when it was incubated with rat brain cortex extract in the present of atp/mg(2+), and the degradation of ad p-tau was also enhanced by sds and was inhibited by lactacystin. |
2005-10-28 |
2023-08-12 |
rat |
| J A Court, M Johnson, D Religa, J Keverne, R Kalaria, E Jaros, I G McKeith, R Perry, J Naslund, E K Perr. Attenuation of Abeta deposition in the entorhinal cortex of normal elderly individuals associated with tobacco smoking. Neuropathology and applied neurobiology. vol 31. issue 5. 2005-10-27. PMID:16150123. |
alzheimer-type pathology (abeta and abnormally phosphorylated tau assessed on the basis of at8 immunoreactivity) together with vascular markers has been compared in age-matched groups of normal elderly smokers and non-smokers in the entorhinal cortex, an area of noted age-related pathology. |
2005-10-27 |
2023-08-12 |
mouse |
| T Katsuno, M Morishima-Kawashima, Y Saito, H Yamanouchi, S Ishiura, S Murayama, Y Ihar. Independent accumulations of tau and amyloid beta-protein in the human entorhinal cortex. Neurology. vol 64. issue 4. 2005-10-18. PMID:15728293. |
independent accumulations of tau and amyloid beta-protein in the human entorhinal cortex. |
2005-10-18 |
2023-08-12 |
human |
| Robyn A Halverson, Jada Lewis, Shanti Frausto, Mike Hutton, Nancy A Mum. Tau protein is cross-linked by transglutaminase in P301L tau transgenic mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 5. 2005-09-13. PMID:15689560. |
we also used double-label immunofluorescence to demonstrate colocalization of phf-1-immunoreactive tau and the transglutaminase-catalyzed cross-link in the hindbrain, spinal cord, and cortex of p301l tau transgenic mice. |
2005-09-13 |
2023-08-12 |
mouse |
| S Williams, K Chalmers, G K Wilcock, S Lov. Relationship of neurofibrillary pathology to cerebral amyloid angiopathy in Alzheimer's disease. Neuropathology and applied neurobiology. vol 31. issue 4. 2005-09-06. PMID:16008825. |
we measured immunolabelling of abnormally phosphorylated tau adjacent to a beta-laden and non-a beta-laden arteries and arterioles, and in cortex away from arteries and arterioles. |
2005-09-06 |
2023-08-12 |
Not clear |
| S Williams, K Chalmers, G K Wilcock, S Lov. Relationship of neurofibrillary pathology to cerebral amyloid angiopathy in Alzheimer's disease. Neuropathology and applied neurobiology. vol 31. issue 4. 2005-09-06. PMID:16008825. |
there were no significant differences between the lobes in measurements of tau labelling, either around blood vessels or elsewhere in the cortex. |
2005-09-06 |
2023-08-12 |
Not clear |