| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L M Storti-Melo, P H Mangonaro, C R Valencio, C Traina Junior, C R B Domingo. Three-dimensional visualization of human hemoglobin phenotypes with HPLC. Genetics and molecular research : GMR. vol 8. issue 1. 2009-08-05. PMID:19440971. |
it allowed separation of the samples with normal hb from those with alpha thalassemia, based on a significant difference (p < 0.05) between the mean values of the "fast" and "a" peaks, demonstrating the need for better evaluation of chromatograms; this method could be used to help diagnose alpha thalassemia in newborns. |
2009-08-05 |
2023-08-12 |
human |
| Ne-Win, Keiko Harano, Teruo Harano, Kyaw-Shwe, Aye-Aye-Myint, Khin-Thander-Aye, Shigeru Okad. Hb Constant Spring [alpha 142, Term-->Gln (TAA>CAA in alpha2)] in the alpha-thalassemia of anemic patients in Myanmar. Hemoglobin. vol 32. issue 5. 2009-07-10. PMID:18932070. |
hb constant spring [alpha 142, term-->gln (taa>caa in alpha2)] in the alpha-thalassemia of anemic patients in myanmar. |
2009-07-10 |
2023-08-12 |
Not clear |
| Ne-Win, Keiko Harano, Teruo Harano, Kyaw-Shwe, Aye-Aye-Myint, Khin-Thander-Aye, Shigeru Okad. Hb Constant Spring [alpha 142, Term-->Gln (TAA>CAA in alpha2)] in the alpha-thalassemia of anemic patients in Myanmar. Hemoglobin. vol 32. issue 5. 2009-07-10. PMID:18932070. |
hb constant spring (hb cs), the gene (alpha(cs)) of which arises from a point mutation in the termination codon of the alpha2-globin gene, is the most prevalent variety of nondeletional alpha-thalassemia (alpha-thal) in asian populations. |
2009-07-10 |
2023-08-12 |
Not clear |
| Ne-Win, Keiko Harano, Teruo Harano, Kyaw-Shwe, Aye-Aye-Myint, Khin-Thander-Aye, Shigeru Okad. Hb Constant Spring [alpha 142, Term-->Gln (TAA>CAA in alpha2)] in the alpha-thalassemia of anemic patients in Myanmar. Hemoglobin. vol 32. issue 5. 2009-07-10. PMID:18932070. |
it is a major cause of hb h disease in compound heterozygotes who have hb cs combined with a duplicated alpha gene deletion (--/alpha(cs)alpha), and it tends to be more severe than hb h disease which is caused by a triple alpha gene deletion (--/-alpha). |
2009-07-10 |
2023-08-12 |
Not clear |
| Ne-Win, Keiko Harano, Teruo Harano, Kyaw-Shwe, Aye-Aye-Myint, Khin-Thander-Aye, Shigeru Okad. Hb Constant Spring [alpha 142, Term-->Gln (TAA>CAA in alpha2)] in the alpha-thalassemia of anemic patients in Myanmar. Hemoglobin. vol 32. issue 5. 2009-07-10. PMID:18932070. |
detection of the alpha(cs) gene for the carriers of alpha-thal-1 and hb h disease was done by the mismatched pcr-rflp (restriction fragment length polymorphism) method and the alpha(cs) gene was found in the homozygous state in an alpha-thal-1 patient and a single gene form in two hb h disease patients. |
2009-07-10 |
2023-08-12 |
Not clear |
| Ne-Win, Keiko Harano, Teruo Harano, Kyaw-Shwe, Aye-Aye-Myint, Khin-Thander-Aye, Shigeru Okad. Hb Constant Spring [alpha 142, Term-->Gln (TAA>CAA in alpha2)] in the alpha-thalassemia of anemic patients in Myanmar. Hemoglobin. vol 32. issue 5. 2009-07-10. PMID:18932070. |
the description of the alpha(cs) gene in myanmar is of great value in the development of an effective procedure for prenatal diagnosis of hb bart's hydrops fetalis syndrome. |
2009-07-10 |
2023-08-12 |
Not clear |
| Kamran Moradkhani, Jean Riou, Alain Francina, Henri Wajcman, Claude Preh. Hb Gerland [alpha 55(E4)Val-->Ala]: a mutation found on the alpha1-globin gene. Hemoglobin. vol 32. issue 5. 2009-07-10. PMID:18932073. |
hb gerland [alpha 55(e4)val-->ala]: a mutation found on the alpha1-globin gene. |
2009-07-10 |
2023-08-12 |
Not clear |
| Kamran Moradkhani, Jean Riou, Alain Francina, Henri Wajcman, Claude Preh. Hb Gerland [alpha 55(E4)Val-->Ala]: a mutation found on the alpha1-globin gene. Hemoglobin. vol 32. issue 5. 2009-07-10. PMID:18932073. |
the hb gerland [alpha 55(e4)val-->ala] mutation has been described in the alpha2-globin gene. |
2009-07-10 |
2023-08-12 |
Not clear |
| Gargi Bhattacharya, Anjali A Sarkar, Debasish Banerjee, Sarmila Chandra, Manikanchan Das, Uma B Dasgupt. Polymerase chain reaction-based search for two alpha-globin gene mutations in India. Hemoglobin. vol 32. issue 5. 2009-07-10. PMID:18932074. |
we have used restriction site-dependent polymerase chain reaction (pcr)-based methodology for detection of the alpha-globin polyadenylation (poly a) signal mutation, aataaa>aata- - and hb sun prairie [alpha 130(h13)ala-->pro, gct>cct (alpha2)] mutation. |
2009-07-10 |
2023-08-12 |
Not clear |
| I Ray-Coquard, S Dussart, C Goillot, D Mayeur, P Debourdeau, H Ghesquieres, T Bachelot, A Le Cesne, B Anglaret, C Agostini, J-P Guastalla, L Lancry, P Biron, F Desseigne, J-Y Bla. A risk model for severe anemia to select cancer patients for primary prophylaxis with epoetin alpha: a prospective randomized controlled trial of the ELYPSE study group. Annals of oncology : official journal of the European Society for Medical Oncology. vol 20. issue 6. 2009-07-02. PMID:19174452. |
this multicentric phase iii trial tested epoetin alpha (epoalpha) administration according to our risk model on the basis of three clinical parameters: hemoglobin (hb) <12 g/dl, lymphocytes 1. |
2009-07-02 |
2023-08-12 |
Not clear |
| Yongliang Huo, Sean C McConnell, Thomas M Rya. Preclinical transfusion-dependent humanized mouse model of beta thalassemia major. Blood. vol 113. issue 19. 2009-06-09. PMID:19258591. |
the mouse adult alpha and beta globin genes were replaced with adult human alpha globin genes (alpha2alpha1) and a human fetal to adult hemoglobin (hb)-switching cassette (gamma(hpfh)deltabeta(0)), respectively. |
2009-06-09 |
2023-08-12 |
mouse |
| Yongliang Huo, Sean C McConnell, Thomas M Rya. Preclinical transfusion-dependent humanized mouse model of beta thalassemia major. Blood. vol 113. issue 19. 2009-06-09. PMID:19258591. |
similar to human infants with ca, fully humanized mice survived postnatally by synthesizing predominantly human fetal hb, hbf (alpha(2)gamma(2)), with a small amount of human minor adult hb, hba2 (alpha(2)delta(2)). |
2009-06-09 |
2023-08-12 |
mouse |
| Roman Aranda, He Cai, Chad E Worley, Elena J Levin, Rong Li, John S Olson, George N Phillips, Mark P Richard. Structural analysis of fish versus mammalian hemoglobins: effect of the heme pocket environment on autooxidation and hemin loss. Proteins. vol 75. issue 1. 2009-05-12. PMID:18831041. |
ile is present at the e11 helical position in most fish hb chains whereas a smaller val residue is present in all mammalian alpha and beta chains. |
2009-05-12 |
2023-08-12 |
cattle |
| Roman Aranda, He Cai, Chad E Worley, Elena J Levin, Rong Li, John S Olson, George N Phillips, Mark P Richard. Structural analysis of fish versus mammalian hemoglobins: effect of the heme pocket environment on autooxidation and hemin loss. Proteins. vol 75. issue 1. 2009-05-12. PMID:18831041. |
especially high rates of hemin loss in perch hb are also due to a lack of electrostatic interaction between his(ce3) and the heme-6 propionate in alpha subunits whereas this interaction does occur in trout iv and bovine hb. |
2009-05-12 |
2023-08-12 |
cattle |
| Nasir A S Al-Allawi, Ameer I A Badi, Hasham Imanian, Nooshin Nikzat, Jaladet M S Jubrael, Hossein Najmabad. Molecular characterization of alpha-thalassemia in the Dohuk region of Iraq. Hemoglobin. vol 33. issue 1. 2009-04-24. PMID:19205971. |
other genotypes identified sporadically were -alpha(4.2)/alpha alpha, alpha(poly a1)alpha/alpha alpha (aataaa>aataag), alpha(adana)alpha/alpha alpha [hb adana, codon 59 (gly-->asp) or hba1:c.179g>a], and alpha(evanston)alpha/alpha alpha [hb evanston, codon 14 (trp-->arg) or hba1:c.43 t>c]. |
2009-04-24 |
2023-08-12 |
Not clear |
| Jonathan P Williams, Hannah Jackson, Brian N Gree. Hb Belleville [beta 10(A7)Ala-->Thr] affects the determination of Hb A1c by routine cation exchange high performance liquid chromatography. Hemoglobin. vol 33. issue 1. 2009-04-24. PMID:19205972. |
to relate hb a(1c) determined by hplc to alpha and beta chain glycation determined by esi-ms, several normal blood samples (5-14% hb a(1c)) were analyzed by both techniques. |
2009-04-24 |
2023-08-12 |
Not clear |
| Jonathan P Williams, Hannah Jackson, Brian N Gree. Hb Belleville [beta 10(A7)Ala-->Thr] affects the determination of Hb A1c by routine cation exchange high performance liquid chromatography. Hemoglobin. vol 33. issue 1. 2009-04-24. PMID:19205972. |
the hb a(1c) levels derived from the alpha and beta chain glycation levels of the diabetic patient (12.9 and 12.4%, respectively) agreed with the sum of the two peaks (12.1%) in the hplc trace. |
2009-04-24 |
2023-08-12 |
Not clear |
| Michel Hochuli, Karin Zurbriggen, Marlis Schmid, Oliver Speer, Philippe Rochat, Beat Frauchiger, Peter Kleinert, Markus Schmugge, Heinz Troxle. A new alpha-globin variant with increased oxygen affinity in a Swiss family: Hb Frauenfeld [alpha 138(H21)Ser-->Phe, TCC>TTC (alpha 2)]. Hemoglobin. vol 33. issue 1. 2009-04-24. PMID:19205974. |
a new alpha-globin variant with increased oxygen affinity in a swiss family: hb frauenfeld [alpha 138(h21)ser-->phe, tcc>ttc (alpha 2)]. |
2009-04-24 |
2023-08-12 |
Not clear |
| Andre F Palmer, Guoyong Sun, David R Harri. Tangential flow filtration of hemoglobin. Biotechnology progress. vol 25. issue 1. 2009-04-16. PMID:19224583. |
lc-ms was used to measure the molecular weight of the alpha (alpha) and beta (beta) globin chains of purified hb. |
2009-04-16 |
2023-08-12 |
human |
| Yalong Zhang, Veer S Bhatt, Guoyong Sun, Peng G Wang, Andre F Palme. Site-selective glycosylation of hemoglobin on Cys beta93. Bioconjugate chemistry. vol 19. issue 11. 2009-03-30. PMID:18925771. |
affff-masls analysis indicates that glycosylation of hb significantly altered the alpha(2)beta(2)-alphabeta equilibrium compared to native hb. |
2009-03-30 |
2023-08-12 |
cattle |