| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Luigi Vitagliano, Alessandro Vergara, Giovanna Bonomi, Antonello Merlino, Cinzia Verde, Guido di Prisco, Barry D Howes, Giulietta Smulevich, Lelio Mazzarell. Spectroscopic and crystallographic characterization of a tetrameric hemoglobin oxidation reveals structural features of the functional intermediate relaxed/tense state. Journal of the American Chemical Society. vol 130. issue 32. 2008-10-06. PMID:18642904. |
here we report a spectroscopic characterization of the autoxidation process of the trematomus newnesi major hb component and the atomic resolution structure (1.25 a) of an intermediate form along the pathway characterized by a different binding and oxidation state of the alpha and beta chains. |
2008-10-06 |
2023-08-12 |
Not clear |
| Paul W Buehler, Florence Vallelian, Malgorzata G Mikolajczyk, Gabriele Schoedon, Thomas Schweizer, Abdu I Alayash, Dominik J Schae. Structural stabilization in tetrameric or polymeric hemoglobin determines its interaction with endogenous antioxidant scavenger pathways. Antioxidants & redox signaling. vol 10. issue 8. 2008-09-29. PMID:18522492. |
modified hb interaction with cd163 and cellular uptake demonstrated an inverse relation with molecular size, irrespective of alpha and beta cross-linking. |
2008-09-29 |
2023-08-12 |
Not clear |
| Henri Wajcman, Jan Traeger-Synodinos, Ioannis Papassotiriou, Piero C Giordano, Cornelis L Harteveld, Véronique Baudin-Creuza, John Ol. Unstable and thalassemic alpha chain hemoglobin variants: a cause of Hb H disease and thalassemia intermedia. Hemoglobin. vol 32. issue 4. 2008-09-22. PMID:18654884. |
unstable and thalassemic alpha chain hemoglobin variants: a cause of hb h disease and thalassemia intermedia. |
2008-09-22 |
2023-08-12 |
Not clear |
| Henri Wajcman, Jan Traeger-Synodinos, Ioannis Papassotiriou, Piero C Giordano, Cornelis L Harteveld, Véronique Baudin-Creuza, John Ol. Unstable and thalassemic alpha chain hemoglobin variants: a cause of Hb H disease and thalassemia intermedia. Hemoglobin. vol 32. issue 4. 2008-09-22. PMID:18654884. |
this is predicted to result in precipitation of the unstable alpha chains or hb variant, a concomitant decrease in the overall quantity of normal alpha-globin in the red cells and a potential degree of anemia and possibly, hemolysis. |
2008-09-22 |
2023-08-12 |
Not clear |
| Varvara Douna, Dimitra Liapi, Dimitrios Kampourakis, Zoe Repapinou, Ioannis Papassotiriou, Alexandra Stamoulakatou, Christos Poziopoulos, Emmanuel Kanavakis, Joanne Traeger-Synodino. First observation of Hb Taybe [Codons 38/39 (-Acc) Thr-->0 (alpha1)] in Greece: clinical and hematological findings in patients with co-inherited alpha+-thalassemia mutations. Hemoglobin. vol 32. issue 4. 2008-09-22. PMID:18654887. |
dna analysis identified the inheritance of common alpha(+)-thalassemia (alpha(+)-thal) mutations in trans to an in-frame 3 bp deletion at codons 38/39 (-acc) on the alpha1-globin gene, previously described as hb taybe. |
2008-09-22 |
2023-08-12 |
Not clear |
| Varvara Douna, Ioannis Papassotiriou, Anna Metaxotou-Mavrommati, Alexandra Stamoulakatou, Dimitra Liapi, Dimitrios Kampourakis, Amalia Tsilimigaki, Emmanuel Kanavakis, Joanne Traeger-Synodino. Further identification of the hyperunstable alpha-globin chain variant Hb Heraklion [codons 36/37 (-CCC); Pro-->0 (alpha1)] in Greek cases with co-inherited alpha+-thalassemia mutations. Hemoglobin. vol 32. issue 4. 2008-09-22. PMID:18654888. |
in all four cases (two unrelated children and two siblings), dna analysis identified common alpha(+)-thalassemia (alpha(+)-thal) mutations in trans to the in frame 3 bp deletion (-ccc) on the alpha1-globin gene between codons 36 and 37, which has previously been reported as hb heraklion in a single greek case. |
2008-09-22 |
2023-08-12 |
Not clear |
| Kamran Moradkhani, Elodie Mazurier, Piero C Giordano, Henri Wajcman, Claude Préh. An alpha0-thalassemia-like mutation: Hb Suan-Dok [alpha109(G16)Leu-->Arg] carried by a recombinant -alpha(3.7) gene. Hemoglobin. vol 32. issue 4. 2008-09-22. PMID:18654893. |
all had a -alpha(3.7) deletion with the recombinant alpha gene carrying the hb suan-dok [alpha109(g16)leuarg] mutation, proposed to be thalassemic. |
2008-09-22 |
2023-08-12 |
Not clear |
| Kamran Moradkhani, Elodie Mazurier, Piero C Giordano, Henri Wajcman, Claude Préh. An alpha0-thalassemia-like mutation: Hb Suan-Dok [alpha109(G16)Leu-->Arg] carried by a recombinant -alpha(3.7) gene. Hemoglobin. vol 32. issue 4. 2008-09-22. PMID:18654893. |
the possibility of hb h disease or hydrops fetalis should be considered when this allele is associated with alpha(+)-thal or with another alpha(0)-thal, respectively. |
2008-09-22 |
2023-08-12 |
Not clear |
| Johannes M W van den Ouweland, Henny van Daal, Corné H Klaassen, Yvonne van Aarssen, Cornelis L Harteveld, Piero C Giordan. The silent hemoglobin alpha chain variant Hb Riccarton [alpha51(CE9)Gly-->Ser] may affect HbA1c determination on the HLC-723 G7 analyzer. Clinical chemistry and laboratory medicine. vol 46. issue 6. 2008-09-04. PMID:18601605. |
the silent hemoglobin alpha chain variant hb riccarton [alpha51(ce9)gly-->ser] may affect hba1c determination on the hlc-723 g7 analyzer. |
2008-09-04 |
2023-08-12 |
Not clear |
| Hamida Mesbah-Amroun, Fatiha Rouabhi, Rolande Ducrocq, Jacques Elio. Molecular basis of alpha-thalassemia in Algeria. Hemoglobin. vol 32. issue 3. 2008-08-12. PMID:18473243. |
the presence of alpha(0)-thal determinants (-alpha(20.5) and --med i) was observed both in hb h patients and in the randomly collected samples. |
2008-08-12 |
2023-08-12 |
Not clear |
| Karra M Markley, Mohamed Elkhalifa, Archana Maini, James D Hoye. Hb Jeddah [alpha68(E17)Asn-->His (alpha1)]: a newly recognized alpha chain variant, seen in combination with Hb S [beta6(A3)Glu-->Val], and found in three separate families of middle eastern origin. Hemoglobin. vol 32. issue 3. 2008-08-12. PMID:18473246. |
hb jeddah [alpha68(e17)asn-->his (alpha1)]: a newly recognized alpha chain variant, seen in combination with hb s [beta6(a3)glu-->val], and found in three separate families of middle eastern origin. |
2008-08-12 |
2023-08-12 |
Not clear |
| Karra M Markley, Mohamed Elkhalifa, Archana Maini, James D Hoye. Hb Jeddah [alpha68(E17)Asn-->His (alpha1)]: a newly recognized alpha chain variant, seen in combination with Hb S [beta6(A3)Glu-->Val], and found in three separate families of middle eastern origin. Hemoglobin. vol 32. issue 3. 2008-08-12. PMID:18473246. |
the index patient presented for hemoglobinopathy screening and was identified to have both this novel alpha chain variant and hb s [beta6(a3)glu-->val, gag(-->)gtg]. |
2008-08-12 |
2023-08-12 |
Not clear |
| Dongzhi Li, Can Liao, Jian Li, Xingmei Xie, Huizhu Zhon. Association of Hb Q-Thailand with heterozygous Hb E in a Chinese patient. Hemoglobin. vol 32. issue 3. 2008-08-12. PMID:18473250. |
interaction of the alpha(q-thailand) and beta(e) chains leads to a hemoglobin (hb) variant, namely hb qe, which differs in electrophoretic mobility and high performance liquid chromatography (hplc) profiles and in the amount of the hb q-thailand variant present in the blood. |
2008-08-12 |
2023-08-12 |
Not clear |
| Guoyong Sun, Andre F Palme. Preparation of ultrapure bovine and human hemoglobin by anion exchange chromatography. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. vol 867. issue 1. 2008-08-05. PMID:18359279. |
pure hb fractions (corresponding to a single band on the sds-page gel) were pooled together and the overall purity and identity assessed by lc-ms. lc-ms analysis yielded two peaks corresponding to the calculated theoretical molecular weight of the alpha and beta chains of hb. |
2008-08-05 |
2023-08-12 |
human |
| Stefan Krivoshiev, Vasil V Todorov, Jacek Manitius, Stanislaw Czekalski, Paul Scigalla, Rossen Koytche. Comparison of the therapeutic effects of epoetin zeta and epoetin alpha in the correction of renal anaemia. Current medical research and opinion. vol 24. issue 5. 2008-07-22. PMID:18394266. |
to assess the therapeutic equivalence of epoetin zeta and epoetin alpha for correction of haemoglobin (hb) concentration in patients with anaemia and chronic kidney disease (ckd) stage 5 maintained on haemodialysis. |
2008-07-22 |
2023-08-12 |
Not clear |
| Zhiyi Chen, Hong-Yuan Luo, Raveen K Basran, Tien-Huei Hsu, Daniel W H Mang, Lalana Nuntakarn, Cathy G Rosenfield, George P Patrinos, Ross C Hardison, Martin H Steinberg, David H K Chu. A T-to-G transversion at nucleotide -567 upstream of HBG2 in a GATA-1 binding motif is associated with elevated hemoglobin F. Molecular and cellular biology. vol 28. issue 13. 2008-07-15. PMID:18443038. |
a t-to-g transversion at nucleotide -567 upstream of hbg2 in a gata-1 binding motif is associated with elevated hemoglobin f. increased fetal hemoglobin (hb f; alpha(2)gamma(2)) production in adults can ameliorate the clinical severity of sickle cell disease and beta-thalassemia major. |
2008-07-15 |
2023-08-12 |
Not clear |
| Sookkasem Khositseth, Apiwan Sirikanaerat, Siri Khoprasert, Sauwalak Opastirakul, Pornchai Kingwatanakul, Wanna Thongnoppakhun, Pa-thai Yenchitsomanu. Hematological abnormalities in patients with distal renal tubular acidosis and hemoglobinopathies. American journal of hematology. vol 83. issue 6. 2008-07-08. PMID:18266205. |
of these 12 patients, three had homozygous g701d/g701d and heterozygous hb e; one compound heterozygous sao/g701d and heterozygous alpha(+)-thalassemia; and one compound heterozygous g701d/a858d and heterozygous hb e. of 6 patients without slc4a1 mutation, two each carried heterozygous or homozygous hb e and one of the latter also had hb h disease (--(sea)/-alpha(4.2)). |
2008-07-08 |
2023-08-12 |
human |
| Hua Naranmandura, Kazuo T Suzuk. Identification of the major arsenic-binding protein in rat plasma as the ternary dimethylarsinous-hemoglobin-haptoglobin complex. Chemical research in toxicology. vol 21. issue 3. 2008-05-30. PMID:18247522. |
in addition, the purified as-bp was shown to consist of two different proteins, haptoglobin (hp) of 37 kda (three bands) and the hemoglobin (hb) alpha chain of 14 kda (single band), using sodium dodecylsulfate-polyacrylamide gel electrophoresis (sds-page) and matrix-assisted laser desorption ionization-time-of-flight mass spectrometry (maldi-tof ms), respectively, suggesting that the as-bp was the ternary dma (iii)-hb-hp complex. |
2008-05-30 |
2023-08-12 |
rat |
| H Andreas Bock, Patricia Hirt-Minkowski, Michel Brünisholz, Gerald Keusch, Simone Rey, Beat von Albertin. Darbepoetin alpha in lower-than-equimolar doses maintains haemoglobin levels in stable haemodialysis patients converting from epoetin alpha/beta. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. vol 23. issue 1. 2008-05-29. PMID:17890745. |
since several observations have suggested that this conversion factor leads to an overestimate of the required darbepoetin dose, the present multicentre study was designed to assess the true conversion ratio by prospectively evaluating the change in darbepoetin alpha dose after conversion from epoetin, which was required to keep haemoglobin (hb) stable. |
2008-05-29 |
2023-08-12 |
Not clear |
| Bushra Moiz, Tariq Moatter, Mashhooda Rasool Hashmi, Nazish Hashmi, Toheed Kauser, Amna Nasir, Mohammad Khurshi. Identification of hemoglobin Q India (alpha 1-64 Asp-His) through ARMS-PCR. First report from Pakistan. Annals of hematology. vol 87. issue 5. 2008-05-27. PMID:18193227. |
this is the first ever report that documents the presence of hb q india (alpha 64 asp to his) in pakistani population. |
2008-05-27 |
2023-08-12 |
human |