| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Viroj Wiwanitki. Tertiary structural analysis of the elongated part of an abnormal hemoglobin, hemoglobin Pakse. International journal of nanomedicine. vol 1. issue 1. 2007-09-18. PMID:17722268. |
abnormalities in the fold structure of globin in hb pakse were identified, and helices additional to the normal alpha globin chains were shown in the elongated part of hb pakse. |
2007-09-18 |
2023-08-12 |
Not clear |
| Upendra Srinivas, Manoranjan Mahapatra, H P Pat. Hb J Meerut, a fast-moving hemoglobin: a study of seven cases from India and a review of literature. American journal of hematology. vol 82. issue 7. 2007-08-31. PMID:17154379. |
only five cases of hb j meerut, an alpha variant fmh, have been reported so far. |
2007-08-31 |
2023-08-12 |
Not clear |
| Piero C Giordano, Akosua Addo-Daaku, Margaretha J Sander, Irene van Rooijen-Nijdam, Peter van Delft, Cornelis L Harteveld, Peter J M J Ko. The rare Hb Showa-Yakushiji [beta110(G12)Leu-->Pro, CTG-->CCG] in combination with an alpha gene triplication found in a Dutch patient during her first pregnancy examination. Hemoglobin. vol 31. issue 2. 2007-07-12. PMID:17486498. |
the rare hb showa-yakushiji [beta110(g12)leu-->pro, ctg-->ccg] in combination with an alpha gene triplication found in a dutch patient during her first pregnancy examination. |
2007-07-12 |
2023-08-12 |
Not clear |
| Piero C Giordano, Akosua Addo-Daaku, Margaretha J Sander, Irene van Rooijen-Nijdam, Peter van Delft, Cornelis L Harteveld, Peter J M J Ko. The rare Hb Showa-Yakushiji [beta110(G12)Leu-->Pro, CTG-->CCG] in combination with an alpha gene triplication found in a Dutch patient during her first pregnancy examination. Hemoglobin. vol 31. issue 2. 2007-07-12. PMID:17486498. |
we report a semi dominant beta-thalassemia (thal) phenotype caused by the rare hb showa-yakushiji [beta110(g12)leu-->pro, ctg-->ccg] mutation in combination with an alpha gene triplication. |
2007-07-12 |
2023-08-12 |
Not clear |
| Mehmet Akif Cürü. Hb H (beta4) disease in Cukurova, Southern Turkey. Hemoglobin. vol 31. issue 2. 2007-07-12. PMID:17486510. |
five patients with hb h disease had the genotype - -(med ii)/alpha(pa 2)alpha one had a hb s heterozygosity (- -(med ii)/alpha(pa 2)alpha + hb as). |
2007-07-12 |
2023-08-12 |
Not clear |
| Parimala Nacharaju, Joel M Friedman, Muthuchidambaram Prabhakaran, Seetharama A Acharya, Belur N Manjul. Combining the influence of two low O2 affinity-inducing chemical modifications of the central cavity of hemoglobin. Biochemistry. vol 46. issue 15. 2007-07-05. PMID:17381072. |
to further modulate the oxygen affinity of hb, the alpha alpha-fumaryl cross-bridge has been introduced into hppr-hba in the mid central cavity. |
2007-07-05 |
2023-08-12 |
Not clear |
| Nirut Siriratmanawong, Charnchai Pinmuang-Ngam, Goonnapa Fucharoen, Supan Fucharoe. Prenatal diagnosis of Hb Bart's hydrops fetalis caused by a genetic compound heterozygosity for two different alpha-thalassemia determinants. Fetal diagnosis and therapy. vol 22. issue 4. 2007-07-03. PMID:17369692. |
to describe prenatal diagnosis of hemoglobin (hb) bart's hydrops fetalis caused by a previously undescribed condition in thailand of the interaction of alpha(o)-thalassemia with the southeast asian (-(sea)) and the thai (-(thai)) deletions in a thai family. |
2007-07-03 |
2023-08-12 |
Not clear |
| Christian Timmann, Jennifer A Evans, Inke R König, André Kleensang, Franz Rüschendorf, Julia Lenzen, Jürgen Sievertsen, Christian Becker, Yeetey Enuameh, Kingsley Osei Kwakye, Ernest Opoku, Edmund N L Browne, Andreas Ziegler, Peter Nürnberg, Rolf D Horstman. Genome-wide linkage analysis of malaria infection intensity and mild disease. PLoS genetics. vol 3. issue 3. 2007-06-18. PMID:17381244. |
by screening 2,551 families in rural ghana, west africa, 108 nuclear families were identified who were exposed to hyperendemic malaria transmission and were homozygous wild-type for the established malaria resistance factors of hemoglobin (hb)s, hbc, alpha(+) thalassemia, and glucose-6-phosphate-dehydrogenase deficiency. |
2007-06-18 |
2023-08-12 |
human |
| Georgi D Efremo. Thalassemias and other hemoglobinopathies in the Republic of Macedonia. Hemoglobin. vol 31. issue 1. 2007-05-09. PMID:17365000. |
three different alpha chain variants among 10 families, seven different beta chain variants among 33 families, two gamma chain variants in two newborns, one variant with an extended alpha chain, and hb lepore among 105 families, have been observed. |
2007-05-09 |
2023-08-12 |
human |
| M Cristina De Rosa, Cristiana Carelli Alinovi, Annamaria Russo, Bruno Giardin. Binding modes of L35 to alpha- and beta-semihemoglobins: structural insights into the inequivalence of alpha- and beta-subunits of hemoglobin. Biochemical and biophysical research communications. vol 354. issue 3. 2007-04-19. PMID:17254552. |
it has been thought for several years that the greatly lowered oxygen affinity, high cooperativity, and heterotropic modulation displayed by tetrameric human hemoglobin (hb) was an exclusive result of the assembly of high affinity alpha(1)beta(1) dimers into alpha(2)beta(2) tetramers. |
2007-04-19 |
2023-08-12 |
human |
| M Cristina De Rosa, Cristiana Carelli Alinovi, Annamaria Russo, Bruno Giardin. Binding modes of L35 to alpha- and beta-semihemoglobins: structural insights into the inequivalence of alpha- and beta-subunits of hemoglobin. Biochemical and biophysical research communications. vol 354. issue 3. 2007-04-19. PMID:17254552. |
however, in recent times, it has been shown that alpha- and beta-semihemoglobins, namely alpha(heme)beta(apo) and alpha(apo)beta(heme), which are dimers of hb characterized by a high affinity for oxygen and lack of cooperativity do respond to effectors such as 2-[4-(3,5-dichlorophenylureido) phenoxy]-2-methylpropionic acid (l35), a bezafibrate (bzf) related compound, by decreasing the ligand affinity to a considerable extent (between 60- and 130-fold). |
2007-04-19 |
2023-08-12 |
human |
| F R Torres, L S Ondei, P J A Zamaro, R U Silva, C E Cavasini, A R B Rossit, R L D Machado, C R Bonini-Domingo. Hemoglobin I-Philadelphia [alpha 16 (A14) LYS-->GLU] heterozygote among blood donors from Brazil. Genetics and molecular research : GMR. vol 5. issue 4. 2007-04-05. PMID:17183481. |
we describe a heterozygous case of hb i-philadelphia [alpha 16 (a14) lys-->glu] in a blood donor from the acre state blood bank, in the brazilian amazon region. |
2007-04-05 |
2023-08-12 |
Not clear |
| Luksana Makonkawkeyoon, Somphon Pharephan, Sanit Makonkawkeyoo. Production of a mouse hybridoma secreting monoclonal antibody highly specific to hemoglobin Bart's (gamma4). Laboratory hematology : official publication of the International Society for Laboratory Hematology. vol 12. issue 4. 2007-02-15. PMID:17118769. |
preliminary results in quantitative determination of hb bart's in hb solution of 3 alpha thalassemia families having at least 1 child with hbh disease and 6 normal subjects indicated that it was possible to quantify hb bart's by our developed elisa with appropriate sensitivity and specificity. |
2007-02-15 |
2023-08-12 |
mouse |
| Corinne Vasseur-Godbillon, Michael C Marden, Piero Giordano, Henri Wajcman, Véronique Baudin-Creuz. Impaired binding of AHSP to alpha chain variants: Hb Groene Hart illustrates a mechanism leading to unstable hemoglobins with alpha thalassemic like syndrome. Blood cells, molecules & diseases. vol 37. issue 3. 2007-02-02. PMID:17052927. |
impaired binding of ahsp to alpha chain variants: hb groene hart illustrates a mechanism leading to unstable hemoglobins with alpha thalassemic like syndrome. |
2007-02-02 |
2023-08-12 |
human |
| Peerapon Wong, Piriya Thanormrat, Suchila Srithipayawan, Nangnoy Jermnim, Sukumarn Niyomthom, Nungruethai Nimnuch, Torpong Sanguansermsr. Risk of a couple having a child with severe thalassemia syndrome, prevalence in lower northern Thailand. The Southeast Asian journal of tropical medicine and public health. vol 37. issue 2. 2007-01-23. PMID:17125000. |
of these, 4.8% had heterozygous alpha thalassemia-1, 1.6% had heterozygous beta thalassemia, 12.4% had heterozygous hemoglobin (hb) e, 2.7% had homozygous hb e and 0.25% of others had abnormal hb. |
2007-01-23 |
2023-08-12 |
Not clear |
| Peerapon Wong, Piriya Thanormrat, Suchila Srithipayawan, Nangnoy Jermnim, Sukumarn Niyomthom, Nungruethai Nimnuch, Torpong Sanguansermsr. Risk of a couple having a child with severe thalassemia syndrome, prevalence in lower northern Thailand. The Southeast Asian journal of tropical medicine and public health. vol 37. issue 2. 2007-01-23. PMID:17125000. |
fifteen couples were at risk for compound heterozygous hb e / beta thalassemia and the remaining 3 were at risk for homozygous alpha thalassemia-1. |
2007-01-23 |
2023-08-12 |
Not clear |
| Viroj Wiwanitki. Secondary and tertiary structure aberration of alpha globin chain in haemoglobin Q-India disorder. Indian journal of pathology & microbiology. vol 49. issue 4. 2007-01-19. PMID:17183835. |
in this study, amino acid sequence of human alpha globin was searched using expasy and used for further mutation to hb q-india disorder. |
2007-01-19 |
2023-08-12 |
human |
| Viroj Wiwanitki. Secondary and tertiary structure aberration of alpha globin chain in haemoglobin Q-India disorder. Indian journal of pathology & microbiology. vol 49. issue 4. 2007-01-19. PMID:17183835. |
the derived sequences, alpha globin chains in both normal and hb q-india disorder, were used for further investigation for secondary and tertiary structures. |
2007-01-19 |
2023-08-12 |
human |
| Viroj Wiwanitki. Secondary and tertiary structure aberration of alpha globin chain in haemoglobin Q-India disorder. Indian journal of pathology & microbiology. vol 49. issue 4. 2007-01-19. PMID:17183835. |
based on this information, the main difference between the predicted alpha globin secondary structures of normal and hb q-india is an extra helix in the hb q-india. |
2007-01-19 |
2023-08-12 |
human |
| Goonnapa Fucharoen, Jaruwan Trithipsombat, Suparerk Sirithawee, Supawadee Yamsri, Yossombat Changtrakul, Kanokwan Sanchaisuriya, Supan Fucharoe. Molecular and hematological profiles of hemoglobin EE disease with different forms of alpha-thalassemia. Annals of hematology. vol 85. issue 7. 2007-01-18. PMID:16565831. |
these included 21 cases with alpha(+)-thalassemia heterozygote (-alpha(3.7)/alphaalpha), one case with alpha(+)-thalassemia heterozygote (-alpha(4.2)/alphaalpha), six cases with hb constant spring heterozygote (alpha(cs)alpha/alphaalpha), four cases with homozygous alpha(+)-thalassemia (-alpha(3.7)/-alpha(3.7)), one case with homozygous alpha(+)-thalassemia (-alpha(4.2)/-alpha(4.2)), two cases with compound alpha(+)-thalassemia/hb constant spring (-alpha(3.7)/alpha(cs)alpha), one case with compound alpha(+)-thalassemia/hb paksé (-alpha(3.7)/alpha(ps)alpha), four cases with alpha(0)-thalassemia heterozygote (--(sea)/alphaalpha), and, unexpectedly, two cases with compound alpha(0)-thalassemia/alpha(+)-thalassemia [(--(sea)/-alpha(3.7)) and (--(sea)/-alpha(4.2))]. |
2007-01-18 |
2023-08-12 |
human |