| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D Z Li, C Liao, J Li, X M Xie, Y N Huang, Q C W. Hemoglobin H hydrops fetalis syndrome resulting from the association of the - -SEA deletion and the alphaQuong Szealpha mutation in a Chinese woman. European journal of haematology. vol 75. issue 3. 2005-09-26. PMID:16104884. |
a case with hb h hydrops fetalis syndrome resulting from the association of the - -(sea) deletion and the alpha(quong sze)alpha mutation is reported. |
2005-09-26 |
2023-08-12 |
Not clear |
| Viroj Wiwanitki. Modeling for tertiary structure of globin chain in Hemoglobin Suan-Dok disorder. Hematology (Amsterdam, Netherlands). vol 10. issue 2. 2005-09-14. PMID:16019464. |
the role of the hemoglobin instability in hb suan-dok in the altered red cell morphology in comparison to the thalassemia-like deficit of alpha globin mrna has not been entirely resolved and needs additional structural study for clarification. |
2005-09-14 |
2023-08-12 |
human |
| Viroj Wiwanitki. Modeling for tertiary structure of globin chain in Hemoglobin Suan-Dok disorder. Hematology (Amsterdam, Netherlands). vol 10. issue 2. 2005-09-14. PMID:16019464. |
in this study the amino acid sequence of human alpha globin was extracted using expasy and compared with that obtained from the hb suan-dok disorder. |
2005-09-14 |
2023-08-12 |
human |
| Viroj Wiwanitki. Modeling for tertiary structure of globin chain in Hemoglobin Suan-Dok disorder. Hematology (Amsterdam, Netherlands). vol 10. issue 2. 2005-09-14. PMID:16019464. |
the derived sequences, alpha globin chains in both the normal and hb suan-dok disorder, were used for further investigation of the tertiary structures. |
2005-09-14 |
2023-08-12 |
human |
| Viroj Wiwanitki. Modeling for tertiary structure of globin chain in Hemoglobin Suan-Dok disorder. Hematology (Amsterdam, Netherlands). vol 10. issue 2. 2005-09-14. PMID:16019464. |
based on this information, there was no significant difference between the predicted alpha globin tertiary structures of normal hemoglobin and hb suan-dok. |
2005-09-14 |
2023-08-12 |
human |
| Viroj Wiwanitki. Modeling for tertiary structure of globin chain in Hemoglobin Suan-Dok disorder. Hematology (Amsterdam, Netherlands). vol 10. issue 2. 2005-09-14. PMID:16019464. |
therefore, from this study we can state that the tertiary structure of alpha globin is not significantly affected by the mutation in the hb suan-dok disorder and that the effect of this hemoglobin abnormality may be silent. |
2005-09-14 |
2023-08-12 |
human |
| Guillermo Martin, Ana Villegas, Fernando Ataulfo González, Paloma Ropero, Ricardo Hojas, Marta Polo, Marta Mateo, Maria Salvador, Celina Benavent. A novel mutation of the alpha2-globin causing alpha(+)-thalassemia: Hb Plasencia [alpha125(H8)Leu--Arg (alpha2). Hemoglobin. vol 29. issue 2. 2005-09-13. PMID:15921163. |
a novel mutation of the alpha2-globin causing alpha(+)-thalassemia: hb plasencia [alpha125(h8)leu--arg (alpha2). |
2005-09-13 |
2023-08-12 |
Not clear |
| Pimlak Charoenkwan, Rawee Taweephon, Rattika Sae-Tung, Pattra Thanarattanakorn, Torpong Sanguansermsr. Molecular and clinical features of Hb H disease in northern Thailand. Hemoglobin. vol 29. issue 2. 2005-09-13. PMID:15921165. |
the nondeletional alpha(+)-thal mutations comprised 55 (53.9%) alleles of hb constant spring (cs) (alpha142, taa --> caa) and three (2.9%) alleles of hb pakse (alpha142, taa --> tat). |
2005-09-13 |
2023-08-12 |
Not clear |
| Lukana Ngiwsara, Chantragan Srisomsap, Pranee Winichagoon, Suthat Fucharoen, Bussara Sae-Ngow, Jisnuson Svast. Hb Kurosaki [alpha7(A5)Lys -->Glu (AAG --> GAG)]: an alpha2-globin gene mutation found in Thailand. Hemoglobin. vol 29. issue 2. 2005-09-13. PMID:15921168. |
hb kurosaki [alpha 7(a5)lys --> glu (aag --> gag)], has been found for the first time in thailand. |
2005-09-13 |
2023-08-12 |
Not clear |
| Majid Yavarian, Mehran Karimi, Amine Zorai, Cornelis L Harteveld, Piero C Giordan. Molecular basis of Hb H disease in southwest Iran. Hemoglobin. vol 29. issue 1. 2005-08-04. PMID:15768554. |
we have analyzed the alpha gene cluster of 13 patients showing the presence of hb h to establish the molecular background of this disease in southwest iran (shiraz and hormozgan provinces). |
2005-08-04 |
2023-08-12 |
Not clear |
| Majid Yavarian, Mehran Karimi, Amine Zorai, Cornelis L Harteveld, Piero C Giordan. Molecular basis of Hb H disease in southwest Iran. Hemoglobin. vol 29. issue 1. 2005-08-04. PMID:15768554. |
using gap-polymerase chain reaction (gap-pcr) and direct dna sequencing we have found the --med-i deletion, the polyadenylation signal (poly a) mutations alphat-saudi alpha and alphat-turkish alpha and hb constant spring (hb cs) in association with the common -alpha3.7 deletion. |
2005-08-04 |
2023-08-12 |
Not clear |
| Majid Yavarian, Mehran Karimi, Amine Zorai, Cornelis L Harteveld, Piero C Giordan. Molecular basis of Hb H disease in southwest Iran. Hemoglobin. vol 29. issue 1. 2005-08-04. PMID:15768554. |
this study has revealed that: 1) at least six genotypes are responsible for hb h disease in the area: .-alpha3.7/ --med-i; -alpha3.7/alphat-saudi alpha; alphat-saudi alpha/alphat-saudi alpha; alphacsalpha/--med-i; --med-i/alphat-turkish alpha; and the atypical forms of hb h disease -alpha3.7/alphacsalpha. |
2005-08-04 |
2023-08-12 |
Not clear |
| Antonio Macciò, Clelia Madeddu, Daniela Massa, Maria C Mudu, Maria R Lusso, Giulia Gramignano, Roberto Serpe, Gian Benedetto Melis, Giovanni Mantovan. Hemoglobin levels correlate with interleukin-6 levels in patients with advanced untreated epithelial ovarian cancer: role of inflammation in cancer-related anemia. Blood. vol 106. issue 1. 2005-08-01. PMID:15774616. |
hb negatively correlated with crp, fbg, interleukin 1beta (il-1beta), il-6, tumor necrosis factor alpha (tnfalpha), and ros, and positively correlated with leptin and glutathione peroxidase (gpx). |
2005-08-01 |
2023-08-12 |
human |
| Stanley L Schrier, Emanuele Angelucc. New strategies in the treatment of the thalassemias. Annual review of medicine. vol 56. 2005-07-19. PMID:15660507. |
in addition to the severe beta thalassemias, hematologists have begun to recognize the more severe forms of alpha thalassemia, namely hemoglobin (hb) h disease and hb h/hb constant spring, as well as the beta compound heterozygote, beta thalassemia/hbe. |
2005-07-19 |
2023-08-12 |
human |
| Xiuling Lu, Chunyang Zheng, Yuhong Xu, Zhiguo S. Disuccinimidyl suberate cross-linked hemoglobin as a novel red blood cell substitute. Science in China. Series C, Life sciences. vol 48. issue 1. 2005-07-18. PMID:15844357. |
analysis by lc-ms demonstrated that the reaction of dss with hb mainly took place between the two alpha subunits within a hb molecule, resulting in stabilization of the tetramer structure. |
2005-07-18 |
2023-08-12 |
rat |
| Jong-Whan Choi, Jong Hyuk Lee, Kwang Ho Lee, Hyean-Woo Lee, Joon Hyung Sohn, Joon Ho Yoon, Byung-Il Yeh, Seung Kyu Park, Kyu Jae Lee, Hyun-Won Ki. Characteristic of aromatic amino acid substitution at alpha 96 of hemoglobin. Journal of biochemistry and molecular biology. vol 38. issue 1. 2005-07-07. PMID:15715956. |
the second mutation, alpha96val -->trp, may compensate the functional defects of r hb (alpha42tyr --> phe), if the stability due to the introduction of trypophan at the alpha 96 position is strong enough to overcome the defect of r hb (alpha42tyr --> phe). |
2005-07-07 |
2023-08-12 |
Not clear |
| Jong-Whan Choi, Jong Hyuk Lee, Kwang Ho Lee, Hyean-Woo Lee, Joon Hyung Sohn, Joon Ho Yoon, Byung-Il Yeh, Seung Kyu Park, Kyu Jae Lee, Hyun-Won Ki. Characteristic of aromatic amino acid substitution at alpha 96 of hemoglobin. Journal of biochemistry and molecular biology. vol 38. issue 1. 2005-07-07. PMID:15715956. |
the present investigation has demonstrated that the presence of the crucible hydrogen bond between alpha 42tyr and beta 99asp is essential for the novel oxygen binding properties of deoxy hb (alpha96val --> trp) . |
2005-07-07 |
2023-08-12 |
Not clear |
| Meiling Lu, Hailin Wang, Xing-Fang Li, Xiufen Lu, William R Cullen, Lora L Arnold, Samuel M Cohen, X Chris L. Evidence of hemoglobin binding to arsenic as a basis for the accumulation of arsenic in rat blood. Chemical research in toxicology. vol 17. issue 12. 2005-06-14. PMID:15606151. |
the binding stoichiometry was consistent with the number of reactive cysteine residues in the alpha and beta chains of hb. |
2005-06-14 |
2023-08-12 |
human |
| Meiling Lu, Hailin Wang, Xing-Fang Li, Xiufen Lu, William R Cullen, Lora L Arnold, Samuel M Cohen, X Chris L. Evidence of hemoglobin binding to arsenic as a basis for the accumulation of arsenic in rat blood. Chemical research in toxicology. vol 17. issue 12. 2005-06-14. PMID:15606151. |
further characterization by nanoelectrospray mass spectrometry of the arsenic species in the rbc of these rats confirmed that most arsenic was bound to the alpha chain of hb. |
2005-06-14 |
2023-08-12 |
human |
| Pedro Cabrales, Amy G Tsai, Robert M Winslow, Marcos Intagliett. Effects of extreme hemodilution with hemoglobin-based O2 carriers on microvascular pressure. American journal of physiology. Heart and circulatory physiology. vol 288. issue 5. 2005-05-31. PMID:15637119. |
a surface-modified polyethylene glycol-conjugated human hemoglobin (mp4) and alpha alpha-cross-linked human hemoglobin (alpha alpha hb) were used to restore oxygen carrying capacity in conditions of extreme hemodilution (hematocrit 11%) in the hamster window model preparation. |
2005-05-31 |
2023-08-12 |
human |