| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pedro Cabrales, Amy G Tsai, Robert M Winslow, Marcos Intagliett. Effects of extreme hemodilution with hemoglobin-based O2 carriers on microvascular pressure. American journal of physiology. Heart and circulatory physiology. vol 288. issue 5. 2005-05-31. PMID:15637119. |
alpha alpha hb caused a greater recovery in map to 94.4 +/- 6.2 mmhg and lowered fcd to 62 +/- 8%. |
2005-05-31 |
2023-08-12 |
human |
| Pedro Cabrales, Amy G Tsai, Robert M Winslow, Marcos Intagliett. Effects of extreme hemodilution with hemoglobin-based O2 carriers on microvascular pressure. American journal of physiology. Heart and circulatory physiology. vol 288. issue 5. 2005-05-31. PMID:15637119. |
however, differences between alpha alpha hb and mp4 in fcd were not statistically significant. |
2005-05-31 |
2023-08-12 |
human |
| Pedro Cabrales, Amy G Tsai, Robert M Winslow, Marcos Intagliett. Effects of extreme hemodilution with hemoglobin-based O2 carriers on microvascular pressure. American journal of physiology. Heart and circulatory physiology. vol 288. issue 5. 2005-05-31. PMID:15637119. |
capillary pressures were in the ranges of 17-21 mmhg for mp4 and 15-19 mmhg for alpha alpha hb, with both significantly lower than baseline (p < 0.05). |
2005-05-31 |
2023-08-12 |
human |
| Pedro Cabrales, Amy G Tsai, Robert M Winslow, Marcos Intagliett. Effects of extreme hemodilution with hemoglobin-based O2 carriers on microvascular pressure. American journal of physiology. Heart and circulatory physiology. vol 288. issue 5. 2005-05-31. PMID:15637119. |
pressure in 80-microm-diameter arterioles was significantly increased with alpha alpha hb relative to mp4 (p < 0.05). |
2005-05-31 |
2023-08-12 |
human |
| Pedro Cabrales, Amy G Tsai, Robert M Winslow, Marcos Intagliett. Effects of extreme hemodilution with hemoglobin-based O2 carriers on microvascular pressure. American journal of physiology. Heart and circulatory physiology. vol 288. issue 5. 2005-05-31. PMID:15637119. |
measurement of changes in arteriolar diameter, microvascular blood flow, and fcd show that there was no statistical difference between using alpha alpha hb and mp4 in extreme hemodilution. |
2005-05-31 |
2023-08-12 |
human |
| Pedro Cabrales, Amy G Tsai, Robert M Winslow, Marcos Intagliett. Effects of extreme hemodilution with hemoglobin-based O2 carriers on microvascular pressure. American journal of physiology. Heart and circulatory physiology. vol 288. issue 5. 2005-05-31. PMID:15637119. |
microvascular resistance in arterioles with a diameter range of 70-80 microm showed an increase relative to control with alpha alpha hb, whereas mp4 caused a decrease. |
2005-05-31 |
2023-08-12 |
human |
| Vip Viprakasit, Gavivann Veerakul, Kleebsabai Sanpakit, Bunchoo Pongtanakul, Worrawut Chinchang, Voravarn S Tanphaichit. Acute haemolytic crisis in a Thai patient with homozygous haemoglobin Constant Spring (Hb CS/CS): a case report. Annals of tropical paediatrics. vol 24. issue 4. 2005-05-31. PMID:15720889. |
it has been shown previously that patients with homozygous hb cs had mild haemolytic anaemia secondary to an accumulation of alpha(cs) chains, which are toxic to red blood cell membrane cytoskeletons. |
2005-05-31 |
2023-08-12 |
Not clear |
| Ren Cai, Jingzhong Liu, Lirong Wang, Xin Liang, Bai Xiao, Liu Su, Yan Zhou, Lizhen Pa. Study on molecular epidemiology of the alpha-thalassemias in Liuzhou City, Guangxi Autonomous Region, China. Hemoglobin. vol 28. issue 4. 2005-05-11. PMID:15658188. |
the severity of the hb h diseases could be classified in the following order: alphacsalpha/--sea (alphaconstant (spring)alpha/--southeast asia); alpha(-4.2)/--sea; alpha(-3.7)/--sea. |
2005-05-11 |
2023-08-12 |
Not clear |
| Fabrizio Dutly, Jörg Fehr, Jeroen Simon Goede, Markus Morf, Heinz Troxler, Hannes Frischknech. A new highly unstable alpha chain variant causing alpha(+)-thalassemia: Hb Zurich Albisrieden [alpha59(E8)Gly-->Arg (alpha2)]. Hemoglobin. vol 28. issue 4. 2005-05-11. PMID:15658192. |
a new highly unstable alpha chain variant causing alpha(+)-thalassemia: hb zurich albisrieden [alpha59(e8)gly-->arg (alpha2)]. |
2005-05-11 |
2023-08-12 |
Not clear |
| Fabrizio Dutly, Jörg Fehr, Jeroen Simon Goede, Markus Morf, Heinz Troxler, Hannes Frischknech. A new highly unstable alpha chain variant causing alpha(+)-thalassemia: Hb Zurich Albisrieden [alpha59(E8)Gly-->Arg (alpha2)]. Hemoglobin. vol 28. issue 4. 2005-05-11. PMID:15658192. |
hb zurich albisrieden [alpha59(e8)gly-->arg (alpha2)] is not detected at the protein level and leads to alpha(+)-thalassemia (thal). |
2005-05-11 |
2023-08-12 |
Not clear |
| Alan R Cohen, Renzo Galanello, Dudley J Pennell, Melody J Cunningham, Elliott Vichinsk. Thalassemia. Hematology. American Society of Hematology. Education Program. 2005-04-21. PMID:15561674. |
alpha thalassemia is also being recognized with increasing frequency in north america, and newborn screening for hemoglobin barts in some states is leading to early detection of hb h disease and hb h constant spring. |
2005-04-21 |
2023-08-12 |
Not clear |
| Kanokwan Sanchaisuriya, Sunisa Chunpanich, Supan Fucharoen, Goonnapa Fucharoen, Pattara Sanchaisuriya, Yossombat Changtraku. Association of Hb Q-Thailand with homozygous Hb E and heterozygous Hb Constant Spring in pregnancy. European journal of haematology. vol 74. issue 3. 2005-03-24. PMID:15693792. |
interaction of the alpha(q-thailand) with the beta(e) globin chains in the proband 1 leads to a hb variant, namely the hb qe. |
2005-03-24 |
2023-08-12 |
human |
| M Molina, M A García Hernández, M J Navarro, M C De Gracia, T Ortuñ. [Change of EPO treatment from subcutaneous epoetin to intravenous epoetin or darbepoetin alpha]. Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia. vol 24. issue 6. 2005-03-15. PMID:15683029. |
this prospective, two-arm, clinical trial assesses the effectiveness in maintaining the levels of haemoglobin (hb) between 11 and 13 g/d1 and the safety of changing the administration route (from subcutaneous to intravenous) of epoetin (rhuepo) alpha at equidose versus a changeover to darbepoetin alpha, taking the exact equivalence in peptide mass between the two as referent in patients with chronic renal insufficiency (cri) in haemodialysis. |
2005-03-15 |
2023-08-12 |
Not clear |
| Chih-Wei Wu, Pao-Chi Liao, Lung Yu, Shan-Tair Wang, Shur-Tzu Chen, Ching-Ming Wu, Yu-Min Ku. Hemoglobin promotes Abeta oligomer formation and localizes in neurons and amyloid deposits. Neurobiology of disease. vol 17. issue 3. 2005-03-07. PMID:15571973. |
immunoprecipitation of abeta in alzheimer's brain homogenate revealed a major co-precipitating 16-kda protein band, which was identified through mass spectrometry as hemoglobin (hb) alpha and beta chains. |
2005-03-07 |
2023-08-12 |
human |
| Lukana Ngiwsara, Chantragan Srisomsap, Pranee Winichagoon, Suthat Fucharoen, Jisnuson Svast. Two cases of compound heterozygosity for Hb Hekinan [alpha27(B8)Glu-->Asp (alpha1)] and alpha-thalassemia in Thailand. Hemoglobin. vol 28. issue 2. 2005-02-16. PMID:15182057. |
however ief gave good separation of hb hekinan and hb a, leading to estimates of hb hekinan (alpha hekinan 2/beta a 2 and alpha hekinan 2/beta e 2) level as 40-43% of total hb. |
2005-02-16 |
2023-08-12 |
Not clear |
| Philippe Lacan, Michel Becchi, Isabelle Zanella-Cleon, Martine Aubry, Martine Ffrench, Nicole Couprie, Alain Francin. Two new beta-chain variants: Hb Tripoli [beta26(B8)Glu-->Ala] and Hb Tizi-Ouzou [beta29(B11)Gly-->Ser]. Hemoglobin. vol 28. issue 3. 2005-02-16. PMID:15481887. |
the presence of microcytosis and hypochromia is explained by an additional homozygous 3.7 kb alpha(+) thalassemic deletion for the carrier of hb tizi-ouzou. |
2005-02-16 |
2023-08-12 |
Not clear |
| Angela L Williamson, Paolo Lecchi, Benjamin E Turk, Youngchool Choe, Peter J Hotez, James H McKerrow, Lewis C Cantley, Mohammed Sajid, Charles S Craik, Alex Louka. A multi-enzyme cascade of hemoglobin proteolysis in the intestine of blood-feeding hookworms. The Journal of biological chemistry. vol 279. issue 34. 2005-02-15. PMID:15199048. |
proteolytic cleavage sites within the hb alpha and beta chains were determined for the three enzymes, identifying a total of 131 cleavage sites. |
2005-02-15 |
2023-08-12 |
Not clear |
| Zhenning He, J Eric Russel. Effect of zeta-globin substitution on the O2-transport properties of Hb S in vitro and in vivo. Biochemical and biophysical research communications. vol 325. issue 4. 2005-01-18. PMID:15555579. |
hemoglobin zeta(2)beta(2)(s) is generated by substituting embryonic zeta-globin subunits for the normal alpha-globin components of hb s (alpha(2)beta(2)(s)). |
2005-01-18 |
2023-08-12 |
mouse |
| Chairat Turbpaiboon, Atchasai Siritantikorn, Wanna Thongnoppakhun, Duangkamon Bunditworapoom, Chanin Limwongse, Pa-thai Yenchitsomanus, Noppadol Siritanaratkul, Prapon Wilaira. Hemoglobin Pakse: presence on red blood cell membrane and detection by polymerase chain reaction-single-strand conformational polymorphism. International journal of hematology. vol 80. issue 2. 2004-12-07. PMID:15481441. |
the presence of alpha(pakse)-globin on membranes of hb pakse-containing red blood cells affords an explanation for the severity of anemia observed in such patients. |
2004-12-07 |
2023-08-12 |
Not clear |
| Cornelis L Harteveld, Pierre W Wijermans, Juliette E L M de Ree, Pauline Ter Hal, Peter Van Delft, Irene H Van Rooijen-Nijdam, Ellen Rasp, Peter J M J Kok, John H M Souverijn, Florens G A Versteegh, Piero C Giordan. A new Hb evanston allele [alpha14(A12)Trp --> Arg] found solely, and in the presence of common alpha-thalassemia deletions, in three independent Asian cases. Hemoglobin. vol 28. issue 1. 2004-10-07. PMID:15008259. |
hb evanston [alpha14(a12)trp --> arg] is considered to be a rare alpha chain mutant, and was originally observed in two black families in 1982, inducing a mild hb h disease phenotype in a homozygous state for the -alpha3.7 deletion ( -alpha(evanston)/ -alpha). |
2004-10-07 |
2023-08-12 |
Not clear |