| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Raja Zahratul Azma, Ainoon Othman, Norazlina Azman, Hafiza Alauddin, Azlin Ithnin, Nurasyikin Yusof, Noor Farisah Razak, Nor Hidayati Sardi, Noor Hamidah Hussi. Co-inheritance of compound heterozygous Hb Constant Spring and a single -alpha(3.7) gene deletion with heterozygous deltabeta thalassaemia: a diagnostic challenge. The Malaysian journal of pathology. vol 34. issue 1. 2012-08-23. PMID:22870600. |
co-inheritance of hb cs and a single -alpha(-3.7) deletion is expected to result at the very least in a clinical phenotype similar to that of two alpha genes deletion. |
2012-08-23 |
2023-08-12 |
Not clear |
| Raja Zahratul Azma, Ainoon Othman, Norazlina Azman, Hafiza Alauddin, Azlin Ithnin, Nurasyikin Yusof, Noor Farisah Razak, Nor Hidayati Sardi, Noor Hamidah Hussi. Co-inheritance of compound heterozygous Hb Constant Spring and a single -alpha(3.7) gene deletion with heterozygous deltabeta thalassaemia: a diagnostic challenge. The Malaysian journal of pathology. vol 34. issue 1. 2012-08-23. PMID:22870600. |
however we demonstrate here a phenotypic modification of alpha thalassemia presumptively as a result of co-inheritance with deltabeta chain abnormality as suggested by the high hb f level. |
2012-08-23 |
2023-08-12 |
Not clear |
| Jan Simoni, Grace Simoni, John F Moeller, Mario Feola, John A Griswold, Donald E Wesso. Adenosine-5'-triphosphate-adenosine-glutathione cross-linked hemoglobin as erythropoiesis-stimulating agent. Artificial organs. vol 36. issue 2. 2012-06-05. PMID:22339724. |
cross-linked hb accelerates erythropoiesis by downregulating nf-kappa b, stabilizing and facilitating hif-1 alpha binding to the epo gene, under both oxygen conditions. |
2012-06-05 |
2023-08-12 |
Not clear |
| Sukanya Sriiam, Amporn Leecharoenkiat, Pathrapol Lithanatudom, Tirawat Wannatung, Saovaros Svasti, Suthat Fucharoen, Jisnuson Svasti, Daranee Chokchaichamnankit, Chantragan Srisomsap, Duncan R Smit. Proteomic analysis of hemoglobin H-constant spring (Hb H-CS) erythroblasts. Blood cells, molecules & diseases. vol 48. issue 2. 2012-06-01. PMID:22154201. |
hemoglobin h disease (hb h) arises through the loss or dysfunction of three of the four alpha globin genes through the co-inheritance of either gross gene deletions or an abnormal hemoglobin which causes a non-deletional loss of α-globin expression. |
2012-06-01 |
2023-08-12 |
Not clear |
| Sukanya Sriiam, Amporn Leecharoenkiat, Pathrapol Lithanatudom, Tirawat Wannatung, Saovaros Svasti, Suthat Fucharoen, Jisnuson Svasti, Daranee Chokchaichamnankit, Chantragan Srisomsap, Duncan R Smit. Proteomic analysis of hemoglobin H-constant spring (Hb H-CS) erythroblasts. Blood cells, molecules & diseases. vol 48. issue 2. 2012-06-01. PMID:22154201. |
this study sought to investigate erythropoiesis in hb h-constant spring (hb h-cs) disease, a common form of hb h disease in southeast asia, caused by the inheritance of the constant spring variant hemoglobin together with deletion of two of the alpha globin genes. |
2012-06-01 |
2023-08-12 |
Not clear |
| Berndt Zur, Michael Ludwig, Birgit Stoffel-Wagne. Hemoglobin Hasharon and hemoglobin NYU in subjects of German origin. Biochemia medica. vol 21. issue 3. 2012-04-09. PMID:22420247. |
we coincidentally detected two cases of hb hasharon, an alpha globin gene mutation, in two heterozygous patients and one case of hb nyu, a delta globin gene mutation, in another patient. |
2012-04-09 |
2023-08-12 |
human |
| Jesús M Planesas, Rosa M Claramunt, Jordi Teixidó, José I Borrell, Violeta I Pérez-Nuen. Improving VEGFR-2 docking-based screening by pharmacophore postfiltering and similarity search postprocessing. Journal of chemical information and modeling. vol 51. issue 4. 2011-09-30. PMID:21417262. |
the resulting docking poses calculated using the alpha hb scoring function implemented in moe are postfiltered according to defined pharmacophore interactions (structure based). |
2011-09-30 |
2023-08-12 |
Not clear |
| Fuanglada Tongprasert, Chanane Wanapirak, Theera Tongson. Maternal serum hCG, PAPP-A and AFP as predictors of hemoglobin Bart disease at mid-pregnancy. Prenatal diagnosis. vol 31. issue 5. 2011-09-22. PMID:21312197. |
to evaluate the ability of maternal serum-free β-human chorionic gonadotrophin (β-hcg), pregnancy-associated plasma protein-a (papp-a), and alpha fetoprotein (afp) levels in the screening of fetuses with hemoglobin (hb) bart's disease among pregnancies at risk. |
2011-09-22 |
2023-08-12 |
Not clear |
| Snehal O Kulkarni, Pradnya P Kanekar, Jyoti P Jog, Prashant A Patil, Smita S Nilegaonkar, Seema S Sarnaik, Pranav R Kshirsaga. Characterisation of copolymer, poly (hydroxybutyrate-co-hydroxyvalerate) (PHB-co-PHV) produced by Halomonas campisalis (MCM B-1027), its biodegradability and potential application. Bioresource technology. vol 102. issue 11. 2011-08-16. PMID:21481588. |
characterisation of polyhydroxyalkanoate (pha) film produced by haloalkalitolerant halomonas campisalis (mcm b-1027) in 14l ss fermenter revealed it to have composition of monomer units, hb:hv as 96:4 as analysed by (1)h nmr indicating the pha as a co-polymer of phb-co-phv, molecular weight by gel permeation chromatography as 2.08 × 10(6), melting temperature 166.51°c, tensile strength 18.8 mpa; two relaxations namely beta transition corresponding to the glass rubber transition and alpha transition corresponding to crystalline relaxation by dynamic mechanical thermal analysis and only one relaxation corresponding to mws interfacial polarisation with activation energy of 129 kj/mol by broadband dielectric spectroscopy. |
2011-08-16 |
2023-08-12 |
Not clear |
| Min Lin, Yue Huang, Li-Ye Yang, Qian Wang, Lei Zhen. Hb Stanleyville II [alpha 78(EF7) Asn→Lys] occurrence in combination with Hb Constant Spring. Blood cells, molecules & diseases. vol 46. issue 2. 2011-06-29. PMID:21093326. |
hb stanleyville ii [alpha 78(ef7) asn→lys] occurrence in combination with hb constant spring. |
2011-06-29 |
2023-08-12 |
Not clear |
| Martin Hergersberg, Saskia Brunner-Agten, Thomas Kühne, Michael Paulussen, Andreas R Hube. A new stable alpha chain variant: Hb Basel [alpha14(A12)Trp-->Leu (alpha1)]. Hemoglobin. vol 34. issue 3. 2011-02-09. PMID:20524822. |
a new stable alpha chain variant: hb basel [alpha14(a12)trp-->leu (alpha1)]. |
2011-02-09 |
2023-08-12 |
Not clear |
| F Xiong, M Sun, X Zhang, R Cai, Y Zhou, J Lou, L Zeng, Q Sun, Q Xiao, X Shang, X Wei, T Zhang, P Chen, X X. Molecular epidemiological survey of haemoglobinopathies in the Guangxi Zhuang Autonomous Region of southern China. Clinical genetics. vol 78. issue 2. 2010-12-07. PMID:20412082. |
the mutational spectrum among the local population for each type of disorder was described, including the first report on the true prevalence of three silent alpha thalassemia defects, -alpha(3.7)/(4.78%), -alpha(4.2)/(1.61%) and hb westmead (alpha(ws)alpha/) (1.57%) and of delta-thalassemia resulting from five novel and two rare mutations never before identified in chinese individuals. |
2010-12-07 |
2023-08-12 |
human |
| Marion Phylipsen, Ingrid P Vogelaar, Rianne A C Schaap, Sandra G J Arkesteijn, George L Boxma, Willem C H van Helden, Irene C M Wildschut, Andrea C de Bruin-Roest, Piero C Giordano, Cornelis L Hartevel. A new alpha(0)-thalassemia deletion found in a Dutch family (--(AW)). Blood cells, molecules & diseases. vol 45. issue 2. 2010-12-07. PMID:20682466. |
because of a 25% risk of hb bart's with hydrops foetalis in the offspring when in combination with another alpha(0)-thalassemia allele, it is important to diagnose this deletion. |
2010-12-07 |
2023-08-12 |
human |
| Raymond M Esquerra, Ignacio López-Peña, Pooncharas Tipgunlakant, Ivan Birukou, Rosa L Nguyen, Jayashree Soman, John S Olson, David S Kliger, Robert A Goldbec. Kinetic spectroscopy of heme hydration and ligand binding in myoglobin and isolated hemoglobin chains: an optical window into heme pocket water dynamics. Physical chemistry chemical physics : PCCP. vol 12. issue 35. 2010-12-03. PMID:20668762. |
internal hydration is higher in the native alpha chains than in the beta chains, in agreement with previous crystallographic results for the subunits within hb tetramers. |
2010-12-03 |
2023-08-12 |
Not clear |
| E George, Tan Jama, A S Nor Azian, A Rahimah, Z Zubaida. A rare case of alpha-thalassaemia intermedia in a Malay patient double heterozygous for alpha(+)-thalassaemia and a mutation in alpha1 globin gene CD59 (GGC --> GAC). The Medical journal of Malaysia. vol 64. issue 4. 2010-11-09. PMID:20954559. |
a rare case of thalassaemia-intermedia involving a non-deletion alpha thalassemia point mutation in the alpha1-globin gene cd59 (ggc --> gac) and a deletion alpha+ (-alpha(3.7)) thalassaemia in which use of high performance liquid chromatography (hplc) c-gram hb subtype profile and dna molecular analysis helped establish the diagnosis. |
2010-11-09 |
2023-08-12 |
Not clear |
| Piero C Giordano, Marjon H Cnossen, Annemarie M S Joosten, Cees A M Jansen, Tineke E Hakvoort, Margreet Bakker-Verweij, Sandra G J Arkesteijn, Peter van Delft, John S Waye, Marelle J Bouva, Cornelis L Hartevel. Codon 24 (TAT>TAG) and codon 32 (ATG>AGG) (Hb Rotterdam): two novel alpha2 gene mutations associated with mild alpha-thalassemia found in the same family after newborn screening. Hemoglobin. vol 34. issue 4. 2010-10-29. PMID:20642333. |
shortly thereafter, hb rotterdam was again found in two unrelated adult females and in a canadian newborn, all of african origin, suggesting that hb rotterdam could be a frequently occurring alpha(t) determinant in the black population. |
2010-10-29 |
2023-08-12 |
Not clear |
| Philippe Joly, Anton Szymanowicz, Marie-Jeanne Neyron, Abdellah Zine, Henri Wajcman, Alain Francin. Hb Charlieu [alpha106(G13)Leu-->Pro (alpha1)]: a new phenotypically silent hemoglobin variant associated with a mild alpha-thalassemia phenotype. Hemoglobin. vol 34. issue 4. 2010-10-29. PMID:20642334. |
as the alpha/beta mrna ratios, determined by reverse-transcriptase real-time quantitative polymerase chain reaction (pcr), are not concordant with an alpha-thalassemia (alpha-thal) state, we hypothesize that the underlying physiopathologic mechanism is an assembling defect of the hb charlieu molecule, rather than an instability of the alpha(charlieu) mrna. |
2010-10-29 |
2023-08-12 |
Not clear |
| Vassiliki Kalotychou, Revekka Tzanetea, Kostas Konstantopoulos, Ioannis Papassotiriou, Ioannis Rombo. Erythrocytosis due to a combination of the high oxygen affinity hemoglobin variant, Hb Olympia [beta20(B2)Val-->Met] with beta- and alpha-thalassemia mutations: first case in the literature. Hemoglobin. vol 34. issue 4. 2010-10-29. PMID:20642336. |
this hemoglobin (hb) variant was found in combination with two thalassemia-type globin gene defects, namely beta(0)-thalassemia (beta(0)-thal), hbb:c.118c>t and alpha(0)-thal (- -(med)). |
2010-10-29 |
2023-08-12 |
Not clear |
| Stephen O Brennan, Sheila Ryken, Tim Cha. Hb Koya Dora [alpha142, Term-->Ser (TAA>TCA in alpha2)]: a rare mutation of the alpha2 gene stop codon associated with alpha-thalassemia. Hemoglobin. vol 34. issue 4. 2010-10-29. PMID:20642339. |
here we identify a homozygous case of hb koya dora and confirm the structure of the 31 residue alpha chain extension. |
2010-10-29 |
2023-08-12 |
Not clear |
| Shruti Trivedi, Naved I Malek, Kamalakanta Behera, Siddharth Pande. Temperature-dependent solvatochromic probe behavior within ionic liquids and (ionic liquid + water) mixtures. The journal of physical chemistry. B. vol 114. issue 24. 2010-09-14. PMID:20518546. |
changes in kamlet-taft parameters dipolarity/polarizability (pi*), hbd acidity (alpha), and hb accepting (hba) basicity (beta) with temperature show interesting trends. |
2010-09-14 |
2023-08-12 |
Not clear |