All Relations between hb and alpha

Publication Sentence Publish Date Extraction Date Species
Liana Tsiatsiani, Michiel Akeroyd, Maurien Olsthoorn, Albert J R Hec. Aspergillus niger Prolyl Endoprotease for Hydrogen-Deuterium Exchange Mass Spectrometry and Protein Structural Studies. Analytical chemistry. vol 89. issue 15. 2019-02-14. PMID:28657298. interestingly, because an-pep peptides are shorter than pepsin-generated peptides, higher sequence resolution could be achieved, especially for pro-containing protein regions in the alpha subunit of hb, revealing new protected hb regions that were not observed with pepsin. 2019-02-14 2023-08-13 human
Katarzyna B Hooks, Jérôme Audoux, Helena Fazli, Sarah Lesjean, Tony Ernault, Nathalie Dugot-Senant, Thierry Leste-Lasserre, Martin Hagedorn, Benoit Rousseau, Coralie Danet, Sophie Branchereau, Laurence Brugières, Sophie Taque, Catherine Guettier, Monique Fabre, Anne Rullier, Marie-Annick Buendia, Thérèse Commes, Christophe F Grosset, Anne-Aurélie Raymon. New insights into diagnosis and therapeutic options for proliferative hepatoblastoma. Hepatology (Baltimore, Md.). vol 68. issue 1. 2018-12-28. PMID:29152775. the transcript profiling separated hb into three distinct subgroups named c1, c2a, and c2b, identifiable by a concise four-gene signature: hydroxysteroid 17-beta dehydrogenase 6, integrin alpha 6, topoisomerase 2-alpha, and vimentin, with topoisomerase 2-alpha being characteristic for the proliferative c2a tumors. 2018-12-28 2023-08-13 Not clear
Steven D Chessler, Donald E Le. Alarming increase in HbA1c and near misdiagnosis of diabetes mellitus resulting from a clinical laboratory instrument upgrade and haemoglobin variant. BMJ case reports. vol 2018. 2018-10-30. PMID:29903779. further investigation, however, revealed, first, that the patient carried a haemoglobin alpha chain mutation (hb wayne) that can sometimes cause assay interference and, second, that although the laboratory's assay methodology had not changed, their assay instrument had. 2018-10-30 2023-08-13 Not clear
Arnab Ghosh, Greer Garee, Elizabeth A Sweeny, Yukio Nakamura, Dennis J Stueh. Hsp90 chaperones hemoglobin maturation in erythroid and nonerythroid cells. Proceedings of the National Academy of Sciences of the United States of America. vol 115. issue 6. 2018-07-24. PMID:29358373. while hemoglobin alpha (hb-α) relies on a specific erythroid chaperone (alpha hb-stabilizing protein, ahsp), the other chaperones that may help mature the partner globins (hb-γ or hb-β) in erythroid cells, or may enable nonerythroid cells to express mature hb, are unknown. 2018-07-24 2023-08-13 Not clear
Erin A Redman, Maria Ramos-Payan, J Scott Mellors, J Michael Ramse. Analysis of Hemoglobin Glycation Using Microfluidic CE-MS: A Rapid, Mass Spectrometry Compatible Method for Assessing Diabetes Management. Analytical chemistry. vol 88. issue 10. 2018-07-13. PMID:27100069. using denaturing conditions, the hemoglobin (hb) tetramer dissociates into the alpha and beta subunits (α- and β-hb), which are then separated via ce directly coupled to ms detection. 2018-07-13 2023-08-13 human
Alessandro Broccoli, Lisa Argnani, Vittorio Stefoni, Letizia Gandolfi, Pier Luigi Zinzan. Efficacy and safety of biosimilar epoetin alpha in patients with chronic lymphoid neoplasms and chemotherapy-induced anaemia: An observational, retrospective, monocentric analysis. Hematological oncology. vol 36. issue 1. 2018-03-05. PMID:28332724. response to epoetin alpha was defined as an increase in hb of >1 g/dl or as an hb > 11 g/dl. 2018-03-05 2023-08-13 Not clear
Alessandro Broccoli, Lisa Argnani, Vittorio Stefoni, Letizia Gandolfi, Pier Luigi Zinzan. Efficacy and safety of biosimilar epoetin alpha in patients with chronic lymphoid neoplasms and chemotherapy-induced anaemia: An observational, retrospective, monocentric analysis. Hematological oncology. vol 36. issue 1. 2018-03-05. PMID:28332724. mean hb levels at the initiation of epoetin alpha was 9.3 ± 0.5 g/dl. 2018-03-05 2023-08-13 Not clear
Alessandro Broccoli, Lisa Argnani, Vittorio Stefoni, Letizia Gandolfi, Pier Luigi Zinzan. Efficacy and safety of biosimilar epoetin alpha in patients with chronic lymphoid neoplasms and chemotherapy-induced anaemia: An observational, retrospective, monocentric analysis. Hematological oncology. vol 36. issue 1. 2018-03-05. PMID:28332724. the biosimilar epoetin alpha was well tolerated and allowed patients with non-hodgkin lymphoma or chronic lymphoproliferative disorders to continue their course of chemotherapy by effectively increasing and maintaining adequate concentrations of hb. 2018-03-05 2023-08-13 Not clear
Amar Das Gupta, Anita Nadkarni, Pallavi Mehta, Manju Goriwale, Manisha Ramani, Pradnya Chaudhary, Vishal Mehrotra, Roshan Cola. Phenotypic expression of HbO Indonesia in two Indian families and its interaction with sickle hemoglobin. Indian journal of pathology & microbiology. vol 60. issue 1. 2017-03-13. PMID:28195097. alpha globin chain variants are clinically significant since they directly influence the structure and function of the hemoglobin (hb) molecules they constitute, either in combination with normal beta globin chains or with variant beta chains, thereby altering the morbidity and mortality associated with the resultant hemoglobinopathies. 2017-03-13 2023-08-13 Not clear
Hilal Özdağ, Inci Yıldız, Nejat Aka. First observation of homozygote Hb Q-Iran (alpha 75 (EF4) Asp-His). Turkish journal of haematology : official journal of Turkish Society of Haematology. vol 25. issue 1. 2016-08-29. PMID:27264151. first observation of homozygote hb q-iran (alpha 75 (ef4) asp-his). 2016-08-29 2023-08-13 Not clear
Roger Théberge, Sergei Dikler, Christian Heckendorf, David H K Chui, Catherine E Costello, Mark E McCom. MALDI-ISD Mass Spectrometry Analysis of Hemoglobin Variants: a Top-Down Approach to the Characterization of Hemoglobinopathies. Journal of the American Society for Mass Spectrometry. vol 26. issue 8. 2016-04-25. PMID:26002792. characterization of an alpha chain variant, hb westmead (α122 his→gln), generated fragments that established the location of the variant. 2016-04-25 2023-08-13 Not clear
Margarita Petropoulou, Amalia Poula, Jan Traeger-Synodinos, Emmanuel Kanavakis, Theodore K Christopoulos, Penelope C Ioanno. Multi-allele DNA biosensor for the rapid genotyping of 'nondeletion' alpha thalassaemia mutations in HBA1 and HBA2 genes by means of multiplex primer extension reaction. Clinica chimica acta; international journal of clinical chemistry. vol 446. 2016-02-22. PMID:25892676. definition of the alpha globin genotype in carriers supports genetic counselling, and in patients with hb h disease is useful to predict prognosis and management options. 2016-02-22 2023-08-13 Not clear
Félix de la Fuente-Gonzalo, Jorge M Nieto, Lara Vinuesa, Julián Sevilla, Joaquín Díaz-Mediavilla, Ana Villegas, Fernando A González, Paloma Roper. Hb Cibeles [α2 CD25(B6) (Gly → Asp)]: a novel alpha chain variant causing alpha-thalassemia. International journal of hematology. vol 100. issue 6. 2015-08-18. PMID:25212678. hb cibeles [α2 cd25(b6) (gly → asp)]: a novel alpha chain variant causing alpha-thalassemia. 2015-08-18 2023-08-13 Not clear
Félix de la Fuente-Gonzalo, Jorge M Nieto, Lara Vinuesa, Julián Sevilla, Joaquín Díaz-Mediavilla, Ana Villegas, Fernando A González, Paloma Roper. Hb Cibeles [α2 CD25(B6) (Gly → Asp)]: a novel alpha chain variant causing alpha-thalassemia. International journal of hematology. vol 100. issue 6. 2015-08-18. PMID:25212678. in this study we show a new structural variant of α-chain, hb cibeles [alpha 25(b6) gly → asp], in heterozygous state, which was undetectable by electrophoretic or chromatographic methods. 2015-08-18 2023-08-13 Not clear
Quentin A Hill, Lisa Farrar, Jim Lordan, Alice Gallienne, Shirley Henderso. A combination of two novel alpha globin variants Hb Bridlington (HBA1) and Hb Taybe (HBA2) resulting in severe hemolysis, pulmonary hypertension, and death. Hematology (Amsterdam, Netherlands). vol 20. issue 1. 2015-07-28. PMID:24716903. a combination of two novel alpha globin variants hb bridlington (hba1) and hb taybe (hba2) resulting in severe hemolysis, pulmonary hypertension, and death. 2015-07-28 2023-08-13 Not clear
S M Hassan, M Al Muslahi, M Al Riyami, E Bakker, C L Harteveld, P C Giordan. Sickle cell anemia and α-thalassemia: a modulating factor in homozygous HbS/S patients in Oman. European journal of medical genetics. vol 57. issue 11-12. 2015-07-24. PMID:25266642. no clear general phenotype correlation was found when patients were compared regardless of the haplotype but overall, patients with homozygous alpha thalassemia (α-/α-) had the highest hb, hct, rbc and the lowest mcv, mch and mchc levels. 2015-07-24 2023-08-13 Not clear
Pranee Winichagoon, Pornnapa Kumpan, Paula Holmes, Jill Finlayson, Christopher Newbound, Arnold Kabral, Benjamin Li, Manit Nuinoon, Terry Fawcett, Chatchai Tayapiwatana, Watchara Kasinrerk, Suthat Fucharoe. Validation of the immunochromatographic strip for α-thalassemia screening: a multicenter study. Translational research : the journal of laboratory and clinical medicine. vol 165. issue 6. 2015-07-23. PMID:25450870. the alpha thal ic strip also has the potential to replace testing for hb h inclusion bodies, as it appears to be more sensitive, specific, and less labor intensive. 2015-07-23 2023-08-13 Not clear
Sushama Parab, Suhas Sakhare, Caesar Sengupta, Arokiaswamy Veluman. Diagnosis of a rare double heterozygous Hb D Punjab/Hb Q India hemoglobinopathy using Sebia capillary zone electrophoresis. Indian journal of pathology & microbiology. vol 57. issue 4. 2015-04-19. PMID:25308024. small peak in z1 zone indicated the presence of alpha chain variant hb q india. 2015-04-19 2023-08-13 Not clear
Sitthichai Panyasai, Sakorn Pornpraser. Hemoglobin Q-Thailand and its combinations with other forms of thalassemia or hemoglobinopathies in northern Thailand. Clinical laboratory. vol 60. issue 7. 2014-09-15. PMID:25134377. there have been no reports for the frequency of hb q-thailand [alpha 74(ef3)asp --> his, gac > cac] and its combinations either with other forms of thalassemia or hemoglobinopathies in northern thailand. 2014-09-15 2023-08-13 Not clear
Raja Zahratul Azma, Othman Ainoon, Alauddin Hafiza, Ithnin Azlin, Abudul Razak Noor Farisah, Sardi Nor Hidayati, Hussin Noor Hamida. Molecular characteristic of alpha thalassaemia among patients diagnosed in UKM Medical Centre. The Malaysian journal of pathology. vol 36. issue 1. 2014-08-21. PMID:24763232. full blood count (fbc) and haemoglobin (hb) analysis using either gel electrophoresis, high performance liquid chromatography (hplc) or capillary zone electrophoresis (ce) are unable to detect definitively alpha thalassaemia carriers. 2014-08-21 2023-08-13 Not clear