| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| W B Qin, X L Yue, L Y Qin, T L Jü, J B Wilson, L H Gu, T H Huisma. Two rare hemoglobin variants: Hb Pyrgos [beta 83(EF7)Gly-->Asp] and Hb Legnano [alpha 141(Hc3)Arg-->Leu] found in Inner Mongolia, P. R. China. Hemoglobin. vol 18. issue 4-5. 1995-03-14. PMID:7852090. |
two rare hemoglobin variants: hb pyrgos [beta 83(ef7)gly-->asp] and hb legnano [alpha 141(hc3)arg-->leu] found in inner mongolia, p. r. china. |
1995-03-14 |
2023-08-12 |
Not clear |
| D D Pobedimskaya, T P Molchanova, T H Huisma. Hb Ramona or alpha (2)24(B5)Tyr-->Cys beta 2. Hemoglobin. vol 18. issue 4-5. 1995-03-14. PMID:7852094. |
hb ramona or alpha (2)24(b5)tyr-->cys beta 2. |
1995-03-14 |
2023-08-12 |
Not clear |
| M Nagai, S Kaminaka, Y Ohba, Y Nagai, Y Mizutani, T Kitagaw. Ultraviolet resonance Raman studies of quaternary structure of hemoglobin using a tryptophan beta 37 mutant. The Journal of biological chemistry. vol 270. issue 4. 1995-02-22. PMID:7829496. |
to characterize the spectral change of trp-beta 37 at the alpha 1 beta 2 interface due to the quaternary structure transition, the uvrr spectra of hb a were compared with the corresponding spectra of hb hirose (trp-beta 37-->ser). |
1995-02-22 |
2023-08-12 |
Not clear |
| M Katsumat. [An industrial toxicological study on workers who synthesize aminophenol and anisidine from chloronitrobenzene]. Nihon Ika Daigaku zasshi. vol 61. issue 6. 1995-02-17. PMID:7829653. |
hemolysate solutions from the blood of workers were applied to isoelectric focusing electrophoresis (ief), and hb species of different valencies were separated; intermediate mhbs, where the heme iron in one of the components of hb, i.e., in the alpha or beta chain was oxidized and mhb where both the alpha and beta chain heme iron oxidized and hb x and y, were separated and easily discernible. |
1995-02-17 |
2023-08-12 |
Not clear |
| J Kister, L Kiger, A Francina, P Hanny, A Szymanowicz, Y Blouquit, D Promé, F Galactéros, J Delaunay, H Wajcma. Hemoglobin Roanne [alpha 94(G1) Asp-->Glu]: a variant of the alpha 1 beta 2 interface with an unexpected high oxygen affinity. Biochimica et biophysica acta. vol 1246. issue 1. 1995-02-07. PMID:7811728. |
in hemoglobin (hb) roanne, the aspartate residue alpha 94(g1) is replaced by a glutamic acid. |
1995-02-07 |
2023-08-12 |
Not clear |
| T P Molchanova, D D Pobedimskaya, T H Huisma. The differences in quantities of alpha 2- and alpha 1-globin gene variants in heterozygotes. British journal of haematology. vol 88. issue 2. 1995-02-02. PMID:7803274. |
we have identified through sequencing of amplified dna the mutations in the alpha 2- and alpha 1-globin genes in 63 individuals with a heterozygosity for an alpha chain abnormal haemoglobin (hb). |
1995-02-02 |
2023-08-12 |
Not clear |
| T P Molchanova, D D Pobedimskaya, T H Huisma. The differences in quantities of alpha 2- and alpha 1-globin gene variants in heterozygotes. British journal of haematology. vol 88. issue 2. 1995-02-02. PMID:7803274. |
the average percentage of the abnormal hb in heterozygotes with alpha 2 mutations (23.5%) was slightly higher than that in heterozygotes with alpha 1 mutations (19.7%) (stable hbs only). |
1995-02-02 |
2023-08-12 |
Not clear |
| F Galacteros, E Girodon, A M'Rad, J Martin, M Goossens, L Jaber, I J Cohen, H Tamary, Y Goshen, R Zaizo. Hb Taybe (alpha 38 or 39 THR deleted): an alpha-globin defect, silent in the heterozygous state and producing severe hemolytic anemia in the homozygous. Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie. vol 317. issue 5. 1995-01-19. PMID:7994622. |
hb taybe (alpha 38 or 39 thr deleted): an alpha-globin defect, silent in the heterozygous state and producing severe hemolytic anemia in the homozygous. |
1995-01-19 |
2023-08-12 |
Not clear |
| A G Tsai, B Friesenecker, R M Winslow, M Intagliett. Functional capillary density changes during blood substitution with alpha alpha Hb and dextran 70: influence on oxygen delivery. Artificial cells, blood substitutes, and immobilization biotechnology. vol 22. issue 3. 1995-01-17. PMID:7527725. |
functional capillary density changes during blood substitution with alpha alpha hb and dextran 70: influence on oxygen delivery. |
1995-01-17 |
2023-08-12 |
Not clear |
| A G Tsai, B Friesenecker, R M Winslow, M Intagliett. Functional capillary density changes during blood substitution with alpha alpha Hb and dextran 70: influence on oxygen delivery. Artificial cells, blood substitutes, and immobilization biotechnology. vol 22. issue 3. 1995-01-17. PMID:7527725. |
we use this rationale to analyze the effectiveness of isovolemic blood substitution with alpha alpha hb (3,5-bis(dibromosalicyl)fumarate) compared to isooncotic and isovolemic hemodilution with dextran 70. |
1995-01-17 |
2023-08-12 |
Not clear |
| A G Tsai, B Friesenecker, R M Winslow, M Intagliett. Functional capillary density changes during blood substitution with alpha alpha Hb and dextran 70: influence on oxygen delivery. Artificial cells, blood substitutes, and immobilization biotechnology. vol 22. issue 3. 1995-01-17. PMID:7527725. |
functional capillary density was maintained during moderate hemodilution with dextran 70, whereas alpha alpha hb exchange caused a gradual reduction in the number of flowing capillaries. |
1995-01-17 |
2023-08-12 |
Not clear |
| A G Tsai, B Friesenecker, R M Winslow, M Intagliett. Functional capillary density changes during blood substitution with alpha alpha Hb and dextran 70: influence on oxygen delivery. Artificial cells, blood substitutes, and immobilization biotechnology. vol 22. issue 3. 1995-01-17. PMID:7527725. |
our findings suggest that augmentation of the o2 content of blood with alpha alpha hb substitution produces similar results in terms of capillary o2 delivery and capacity as isovolemic and isooncotic hemodilution with dextran 70. |
1995-01-17 |
2023-08-12 |
Not clear |
| S S Panter, K D Vandegriff, P O Yan, R F Rega. Assessment of hemoglobin-dependent neurotoxicity: alpha-alpha crosslinked hemoglobin. Artificial cells, blood substitutes, and immobilization biotechnology. vol 22. issue 3. 1995-01-17. PMID:7994364. |
adult human hemoglobin a0 (hba0) has been shown to be neurotoxic, and we wish to report on similar studies conducted using a modified hemoglobin, which has been crosslinked between the alpha subunits (alpha-alpha hb). |
1995-01-17 |
2023-08-12 |
mouse |
| K D Vandegriff, Y C Le Tellie. A comparison of rates of heme exchange: site-specifically cross-linked versus polymerized human hemoglobins. Artificial cells, blood substitutes, and immobilization biotechnology. vol 22. issue 3. 1995-01-17. PMID:7994367. |
the total fitted amplitudes of the reaction depended upon the specific modification: beta beta-cross-linked hbs < alpha alpha-cross-linked hb approximately glycolaldehyde polymerized hb < glutaraldehyde polymerized hb < hba0. |
1995-01-17 |
2023-08-12 |
human |
| M Samaja, R Motterlini, E Rovid. Enhanced oxidation of bis(3,5-dibromosalicyl) fumarate alpha-alpha cross linked hemoglobin by free radicals generated by xanthine/xanthine oxidase. Artificial cells, blood substitutes, and immobilization biotechnology. vol 22. issue 3. 1995-01-17. PMID:7994373. |
we monitored the kinetics of the oxidation of stripped hb (shb), purified hba0 and alpha-alpha cross-linked hb (hbxl99 alpha) at [hb] in the 5 to 150 microm (heme) range. |
1995-01-17 |
2023-08-12 |
human |
| M Samaja, R Motterlini, E Rovid. Enhanced oxidation of bis(3,5-dibromosalicyl) fumarate alpha-alpha cross linked hemoglobin by free radicals generated by xanthine/xanthine oxidase. Artificial cells, blood substitutes, and immobilization biotechnology. vol 22. issue 3. 1995-01-17. PMID:7994373. |
for increasing [hb], the oxidation halftime (t1/2) increased for all hbs, but t1/2 was always less for hbxl99 alpha than for hba0 and shb. |
1995-01-17 |
2023-08-12 |
human |
| M Samaja, R Motterlini, E Rovid. Enhanced oxidation of bis(3,5-dibromosalicyl) fumarate alpha-alpha cross linked hemoglobin by free radicals generated by xanthine/xanthine oxidase. Artificial cells, blood substitutes, and immobilization biotechnology. vol 22. issue 3. 1995-01-17. PMID:7994373. |
such feature was attributed to the lower affinity for o2 of hbxl99 alpha and may represent a serious problem for use of this hb as blood substitute. |
1995-01-17 |
2023-08-12 |
human |
| V W Macdonald, R Motterlin. Vasoconstrictor effects in isolated rabbit heart perfused with bis(3,5-dibromosalicyl)fumarate cross-linked hemoglobin (alpha alpha Hb). Artificial cells, blood substitutes, and immobilization biotechnology. vol 22. issue 3. 1995-01-17. PMID:7994376. |
vasoconstrictor effects in isolated rabbit heart perfused with bis(3,5-dibromosalicyl)fumarate cross-linked hemoglobin (alpha alpha hb). |
1995-01-17 |
2023-08-12 |
human |
| V W Macdonald, R Motterlin. Vasoconstrictor effects in isolated rabbit heart perfused with bis(3,5-dibromosalicyl)fumarate cross-linked hemoglobin (alpha alpha Hb). Artificial cells, blood substitutes, and immobilization biotechnology. vol 22. issue 3. 1995-01-17. PMID:7994376. |
to study the mechanism by which cell-free hemoglobin preparations may alter coronary vascular reactivity, we investigated the effect of human hemoglobin cross-linked between alpha chains with bis(3,5-dibromosalicyl)fumarate (alpha alpha hb) on the vasomotor response to acetylcholine (ach) in isolated perfused rabbit hearts. |
1995-01-17 |
2023-08-12 |
human |
| V W Macdonald, R Motterlin. Vasoconstrictor effects in isolated rabbit heart perfused with bis(3,5-dibromosalicyl)fumarate cross-linked hemoglobin (alpha alpha Hb). Artificial cells, blood substitutes, and immobilization biotechnology. vol 22. issue 3. 1995-01-17. PMID:7994376. |
dose-response curves were generated by monitoring the increase in coronary pressure during serial addition of 0.2-10 microm ach before, during and after 20 min infusion of three test solutions: a) 0.1 g/dl alpha alpha hb (62 microm heme); b) 0.1 g/dl alpha alpha hb plus 60 microm deferoxamine (dfo); c) 50 microm ng-nitro-l-arginine methyl ester (l-name), a specific inhibitor of nitric oxide (no) synthase. |
1995-01-17 |
2023-08-12 |
human |