| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Dumoulin, L Kiger, R Jiang, V Baudin, C Vasseur, S G Sligar, M C Marden, J Pagnier, C Poyar. Loss of allosteric behaviour in recombinant hemoglobin alpha 2 beta 2(92)(F8) His-->Ala: restoration upon addition of strong effectors. FEBS letters. vol 374. issue 1. 1995-12-05. PMID:7589508. |
to study the effects of the loss of the iron proximal histidine bond, we have engineered the alpha 2 beta 2(f8)h92a recombinant hb. |
1995-12-05 |
2023-08-12 |
Not clear |
| P Winichagoon, S Fucharoen, S Kanokpongsakdi, Y Fukumak. Detection of alpha-thalassemia-1 (Southeast Asian type) and its application for prenatal diagnosis. Clinical genetics. vol 47. issue 6. 1995-11-20. PMID:7554366. |
in hb bart's hydrops fetalis (--/--), only the 570 bp fragment was obtained, whereas the 194 bp fragment was amplified in normal individual (alpha alpha/alpha alpha) and alpha-thalassemia-2 trait (-alpha/alpha alpha). |
1995-11-20 |
2023-08-12 |
Not clear |
| P Winichagoon, S Fucharoen, S Kanokpongsakdi, Y Fukumak. Detection of alpha-thalassemia-1 (Southeast Asian type) and its application for prenatal diagnosis. Clinical genetics. vol 47. issue 6. 1995-11-20. PMID:7554366. |
both 570 and 194 bp fragments were detected in alpha-thalassemia-1 trait (--/alpha alpha) and hb h patients (--/-alpha). |
1995-11-20 |
2023-08-12 |
Not clear |
| J T Prchal, B Adler, J B Wilson, E Baysal, W B Qin, T P Molchanova, D D Pobedimskaya, E G Kazanetz, T H Huisma. Hb Bibba or alpha 2 136(H19)Leu-->Pro beta 2 in a Caucasian family from Alabama. Hemoglobin. vol 19. issue 3-4. 1995-11-06. PMID:7558871. |
hb bibba or alpha 2 136(h19)leu-->pro beta 2 in a caucasian family from alabama. |
1995-11-06 |
2023-08-12 |
Not clear |
| J T Prchal, B Adler, J B Wilson, E Baysal, W B Qin, T P Molchanova, D D Pobedimskaya, E G Kazanetz, T H Huisma. Hb Bibba or alpha 2 136(H19)Leu-->Pro beta 2 in a Caucasian family from Alabama. Hemoglobin. vol 19. issue 3-4. 1995-11-06. PMID:7558871. |
several members of a large caucasian family who presented with a congenital heinz body hemolytic anemia were found to be carriers of the unstable hb bibba or alpha 2 136(h19)leu-->pro beta 2. |
1995-11-06 |
2023-08-12 |
Not clear |
| A Gürgey, C Altay, L H Gu, J Y Leonova, A Delibalta, C Oner, T H Huisma. Hb Hakkari or alpha 2 beta 2 31(B13)Leu-->Arg, a severely unstable hemoglobin variant associated with numerous intra-erythroblastic inclusions and erythroid hyperplasia of the bone marrow. Hemoglobin. vol 19. issue 3-4. 1995-11-06. PMID:7558872. |
hb hakkari or alpha 2 beta 2 31(b13)leu-->arg, a severely unstable hemoglobin variant associated with numerous intra-erythroblastic inclusions and erythroid hyperplasia of the bone marrow. |
1995-11-06 |
2023-08-12 |
Not clear |
| A Gürgey, C Altay, L H Gu, J Y Leonova, A Delibalta, C Oner, T H Huisma. Hb Hakkari or alpha 2 beta 2 31(B13)Leu-->Arg, a severely unstable hemoglobin variant associated with numerous intra-erythroblastic inclusions and erythroid hyperplasia of the bone marrow. Hemoglobin. vol 19. issue 3-4. 1995-11-06. PMID:7558872. |
a severely unstable hemoglobin variant, hb hakkari or alpha 2 beta 2 31 (b13)leu-->arg, has been observed in a 5-year-old turkish girl with a severe hemolytic anemia without heinz body formation. |
1995-11-06 |
2023-08-12 |
Not clear |
| T Harano, K Harano, K Imai, T Murakami, H Matsubar. Hb Kurosaki [alpha 7(A5)Lys-->Glu]: a new alpha chain variant found in a Japanese woman. Hemoglobin. vol 19. issue 3-4. 1995-11-06. PMID:7558876. |
hb kurosaki [alpha 7(a5)lys-->glu]: a new alpha chain variant found in a japanese woman. |
1995-11-06 |
2023-08-12 |
Not clear |
| E J Harthoorn-Lasthuizen, F A Nabben, E G Kazanetz, L H Gu, T P Molchanova, T H Huisma. HB Mizuho or alpha 2 beta 2 68(E12)Leu-->Pro in a young Dutch boy. Hemoglobin. vol 19. issue 3-4. 1995-11-06. PMID:7558877. |
hb mizuho or alpha 2 beta 2 68(e12)leu-->pro in a young dutch boy. |
1995-11-06 |
2023-08-12 |
Not clear |
| T P Molchanova, N S Smetanina, T H Huisma. A second, elongated, alpha 2-globin mRNA is present in reticulocytes from normal persons and subjects with terminating codon or poly A mutations. Biochemical and biophysical research communications. vol 214. issue 3. 1995-11-02. PMID:7575528. |
with an rt-pcr procedure we have identified a second, elongated, alpha 2-globin mrna in reticulocytes of normal persons and of patients with alpha-thal, particularly those with mutations in the terminating codon (taa-->caa; hb constant spring; taa-->tat, hb paksé) or in the poly a site (aataaa-->aataag). |
1995-11-02 |
2023-08-12 |
human |
| W Kaca, R I Roth, K D Vandegriff, G C Chen, F A Kuypers, R M Winslow, J Levi. Effects of bacterial endotoxin on human cross-linked and native hemoglobins. Biochemistry. vol 34. issue 35. 1995-10-13. PMID:7669775. |
in the present study, the influence of lps on the structure of native human hba0 and covalently cross-linked hb (alpha alpha hb) was studied by analyzing the absorption and circular dichroic spectra of hb in the wavelength region of 200-650 nm. |
1995-10-13 |
2023-08-12 |
human |
| W Kaca, R I Roth, K D Vandegriff, G C Chen, F A Kuypers, R M Winslow, J Levi. Effects of bacterial endotoxin on human cross-linked and native hemoglobins. Biochemistry. vol 34. issue 35. 1995-10-13. PMID:7669775. |
in conclusion, analyses of absorption and circular dichroic spectra reveal the potential of lps to produce a facilitated oxidation of both alpha alpha-cross-linked human hb and native human hba0, without substantial changes in the secondary structure of the globin. |
1995-10-13 |
2023-08-12 |
human |
| M E Fabry, A Sengupta, S M Suzuka, F Costantini, E M Rubin, J Hofrichter, G Christoph, E Manci, D Culberson, S M Factor, R L Nage. A second generation transgenic mouse model expressing both hemoglobin S (HbS) and HbS-Antilles results in increased phenotypic severity. Blood. vol 86. issue 6. 1995-10-12. PMID:7662990. |
hematocrit, hb, and mean corpuscular hb were normal for all transgenic mice, but reticulocyte levels were higher for the doubly transgenic mice versus alpha h beta s [beta mdd] mice older than 30 days (10.0% +/- 1.0% v 4.3% +/- 0.4%; p < .001, mean +/- se, n = 20 and n = 10, respectively) and control mice (3.9% +/- 0.4%). |
1995-10-12 |
2023-08-12 |
mouse |
| M E Fabry, A Sengupta, S M Suzuka, F Costantini, E M Rubin, J Hofrichter, G Christoph, E Manci, D Culberson, S M Factor, R L Nage. A second generation transgenic mouse model expressing both hemoglobin S (HbS) and HbS-Antilles results in increased phenotypic severity. Blood. vol 86. issue 6. 1995-10-12. PMID:7662990. |
delay times for polymerization of hb in red blood cells from alpha h beta s beta s-ant[beta mdd] mice were shorter than those of alpha h beta s[beta mdd] mice, and there were fewer cells with delay times greater than 100 seconds. |
1995-10-12 |
2023-08-12 |
mouse |
| G R Gray, H E Manson, L H Gu, Leonova JYe, T H Huisma. Hb Lulu Island (alpha 2 beta 2 107[G9]Gly-->Asp)-beta zero- thalassemia (codon 15; TGG-->TAG), a form of thalassemia intermedia. American journal of hematology. vol 50. issue 1. 1995-10-12. PMID:7668221. |
hb lulu island (alpha 2 beta 2 107[g9]gly-->asp)-beta zero- thalassemia (codon 15; tgg-->tag), a form of thalassemia intermedia. |
1995-10-12 |
2023-08-12 |
Not clear |
| G R Gray, H E Manson, L H Gu, Leonova JYe, T H Huisma. Hb Lulu Island (alpha 2 beta 2 107[G9]Gly-->Asp)-beta zero- thalassemia (codon 15; TGG-->TAG), a form of thalassemia intermedia. American journal of hematology. vol 50. issue 1. 1995-10-12. PMID:7668221. |
the level of hba2 was greatly increased (6.5-7.0%) as was the delta chain level (12% of total non-alpha) probably because of the instability of hb lulu island and the decreased ability of the beta x chain to form dimers with the normal alpha chain. |
1995-10-12 |
2023-08-12 |
Not clear |
| R Motterlini, R Foresti, K Vandegriff, M Intaglietta, R M Winslo. Oxidative-stress response in vascular endothelial cells exposed to acellular hemoglobin solutions. The American journal of physiology. vol 269. issue 2 Pt 2. 1995-09-22. PMID:7653629. |
porcine aortic endothelial cells were incubated for 6 h in the presence of 60 microm unmodified hemoglobin a0 (hba0), hemoglobin cross-linked between the alpha-chains with bis-(3,5-dibromosalicyl)fumarate (alpha alpha hb), or cyanomet-alpha alpha-hemoglobin (cnmet alpha alpha hb). |
1995-09-22 |
2023-08-12 |
Not clear |
| R Motterlini, R Foresti, K Vandegriff, M Intaglietta, R M Winslo. Oxidative-stress response in vascular endothelial cells exposed to acellular hemoglobin solutions. The American journal of physiology. vol 269. issue 2 Pt 2. 1995-09-22. PMID:7653629. |
endothelial ho activity augmented 4.1-fold in the presence of alpha alpha hb, 2.7-fold with hba0, and 1.8-fold with cnmet alpha alpha hb over the control value. |
1995-09-22 |
2023-08-12 |
Not clear |
| R Motterlini, R Foresti, K Vandegriff, M Intaglietta, R M Winslo. Oxidative-stress response in vascular endothelial cells exposed to acellular hemoglobin solutions. The American journal of physiology. vol 269. issue 2 Pt 2. 1995-09-22. PMID:7653629. |
deferoxamine, but not catalase or dimethylthiourea, partially attenuated the ho induction produced by alpha alpha hb. |
1995-09-22 |
2023-08-12 |
Not clear |
| R Motterlini, R Foresti, K Vandegriff, M Intaglietta, R M Winslo. Oxidative-stress response in vascular endothelial cells exposed to acellular hemoglobin solutions. The American journal of physiology. vol 269. issue 2 Pt 2. 1995-09-22. PMID:7653629. |
the rates of methemoglobin formation exhibited a linear relationship over the time of incubation (r = 0.94), and the apparent rate constant was 1.8-fold higher for alpha alpha hb (0.023 h-1) than for hba0 (0.013 h-1). |
1995-09-22 |
2023-08-12 |
Not clear |