| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Kosh. Sickle cell disease and pregnancy. Blood reviews. vol 9. issue 3. 1996-03-01. PMID:8563517. |
sickle cell disease refers to a group of genetic disorders characterised by the predominance of hemoglobin s. this includes sickle cell anemia (ss) sickle hemoglobin c disease (sc), sickle beta thalassemia plus (s beta + thal), sickle beta thalassemia zero (beta zero thal), sickle with alpha thalassemia (ss alpha thal) and rare combinations of sickle hemoglobin with hb d, hb o, etc. |
1996-03-01 |
2023-08-12 |
Not clear |
| F Morlé, A Francina, R Ducrocq, H Wajcman, C Gonnet, N Philippe, G Souillet, J Gode. A new alpha chain variant Hb Sallanches [alpha 2 104(G11) Cys-->Tyr] associated with HbH disease in one homozygous patient. British journal of haematology. vol 91. issue 3. 1996-02-23. PMID:8555062. |
a new alpha chain variant hb sallanches [alpha 2 104(g11) cys-->tyr] associated with hbh disease in one homozygous patient. |
1996-02-23 |
2023-08-12 |
Not clear |
| S B Olsen, D B Tang, M R Jackson, E R Gomez, B Ayala, B M Alvin. Enhancement of platelet deposition by cross-linked hemoglobin in a rat carotid endarterectomy model. Circulation. vol 93. issue 2. 1996-02-20. PMID:8548906. |
we postulated that binding of no by cross-linked hemoglobin (alpha alpha hb) could also increase platelet deposition at sites of subintimal injury. |
1996-02-20 |
2023-08-12 |
human |
| A Qualtieri, E V De Marco, L Crescibene, V Andreoli, A Bagalà, M Scornalenchi, C Brancatl, C M Grec. Hb J-Wenchang-Wuming or alpha 11(A9)Lys-->Gln in an Italian woman. Hemoglobin. vol 19. issue 5. 1996-02-05. PMID:8537231. |
hb j-wenchang-wuming or alpha 11(a9)lys-->gln in an italian woman. |
1996-02-05 |
2023-08-12 |
Not clear |
| H Wajcman, Y Blouquit, A Lahary, A M Soummer, P Groff, J Bardakdjian, C Préhu, J Riou, C Godard, F Galactèro. Three new neutral alpha chain variants: Hb Bois Guillaume [alpha 65(E14(Ala-->Val], Hb Mantes-la-Jolie [alpha 79(EF8)Ala-Thr], and Hb Mosella [alpha 111(G18)Ala-->Thr]. Hemoglobin. vol 19. issue 5. 1996-02-05. PMID:8537232. |
three new neutral alpha chain variants: hb bois guillaume [alpha 65(e14(ala-->val], hb mantes-la-jolie [alpha 79(ef8)ala-thr], and hb mosella [alpha 111(g18)ala-->thr]. |
1996-02-05 |
2023-08-12 |
Not clear |
| M J Romero, M L Garrido, E Abril, F Garrido, J M de Pablo. Detection of Hb J-Camagüey [alpha 141(HC3)Arg-->Gly] in three Spanish families. Hemoglobin. vol 19. issue 5. 1996-02-05. PMID:8537233. |
detection of hb j-camagüey [alpha 141(hc3)arg-->gly] in three spanish families. |
1996-02-05 |
2023-08-12 |
Not clear |
| N S Smetanina, J Y Leonova, N Levy, T H Huisma. Identification of several alpha-globin gene variations in a small Laotian family. Acta haematologica. vol 94. issue 3. 1996-01-18. PMID:7502632. |
the father carried the 4.2-kb deletion on one chromosome and a taa-->caa mutation at the terminating codon of the alpha 2-gene (hb constant spring or cs) on the other chromosome. |
1996-01-18 |
2023-08-12 |
Not clear |
| N S Smetanina, J Y Leonova, N Levy, T H Huisma. Identification of several alpha-globin gene variations in a small Laotian family. Acta haematologica. vol 94. issue 3. 1996-01-18. PMID:7502632. |
moreover, the remaining alpha 1-globin gene on the chromosome with the 4.2-kb deletion was mutated at codon 74 (gac-->cac; asp-->his; hb q-thailand). |
1996-01-18 |
2023-08-12 |
Not clear |
| N S Smetanina, J Y Leonova, N Levy, T H Huisma. Identification of several alpha-globin gene variations in a small Laotian family. Acta haematologica. vol 94. issue 3. 1996-01-18. PMID:7502632. |
the mother had the 3.7-kb deletion on one chromosome and a taa-->tat mutation at the terminating codon of the alpha 2-globin gene (hb paksé) of the second chromosome. |
1996-01-18 |
2023-08-12 |
Not clear |
| J R Hes. Review of modified hemoglobin research at Letterman: attempts to delineate the toxicity of cell-free tetrameric hemoglobin. Artificial cells, blood substitutes, and immobilization biotechnology. vol 23. issue 3. 1996-01-11. PMID:7493049. |
human mononuclear cells release tnf alpha and il-8 when exposed to chromatographically purified human hb (hba0). |
1996-01-11 |
2023-08-12 |
mouse |
| J R Hes. Review of modified hemoglobin research at Letterman: attempts to delineate the toxicity of cell-free tetrameric hemoglobin. Artificial cells, blood substitutes, and immobilization biotechnology. vol 23. issue 3. 1996-01-11. PMID:7493049. |
in rabbits hba0 and human hb cross-linked with bis(3,5-dibromosalicyl) fumarate (alpha alpha hb) caused hypertension and pulmonary arteritis. |
1996-01-11 |
2023-08-12 |
mouse |
| J R Hes. Review of modified hemoglobin research at Letterman: attempts to delineate the toxicity of cell-free tetrameric hemoglobin. Artificial cells, blood substitutes, and immobilization biotechnology. vol 23. issue 3. 1996-01-11. PMID:7493049. |
in swine, hba0 and alpha alpha hb caused systemic and pulmonary hypertension and a doubling of the vascular resistance that was equivalent to that seen with inhibition of nitric oxide synthesis. |
1996-01-11 |
2023-08-12 |
mouse |
| J R Hes. Review of modified hemoglobin research at Letterman: attempts to delineate the toxicity of cell-free tetrameric hemoglobin. Artificial cells, blood substitutes, and immobilization biotechnology. vol 23. issue 3. 1996-01-11. PMID:7493049. |
acute renal failure seen after administration hba0, did not appear after alpha alpha hb. |
1996-01-11 |
2023-08-12 |
mouse |
| J R Hes. Review of modified hemoglobin research at Letterman: attempts to delineate the toxicity of cell-free tetrameric hemoglobin. Artificial cells, blood substitutes, and immobilization biotechnology. vol 23. issue 3. 1996-01-11. PMID:7493049. |
infusion of cyanomet-alpha alpha hb did not cause the increased vascular resistance seen after alpha alpha hb. |
1996-01-11 |
2023-08-12 |
mouse |
| J R Hes. Review of modified hemoglobin research at Letterman: attempts to delineate the toxicity of cell-free tetrameric hemoglobin. Artificial cells, blood substitutes, and immobilization biotechnology. vol 23. issue 3. 1996-01-11. PMID:7493049. |
the infusion of 1-arginine or nitroglycerine with alpha alpha hb did not prevent the increased vascular resistance and decreased cardiac output or allow the increased oxygen carrying capacity provided by hb in the plasma from translating into improved oxygen delivery or improved oxygen consumption. |
1996-01-11 |
2023-08-12 |
mouse |
| R Motterlini, R Foresti, K Vandegriff, R M Winslo. The autoxidation of alpha alpha cross-linked hemoglobin: a possible role in the oxidative stress to endothelium. Artificial cells, blood substitutes, and immobilization biotechnology. vol 23. issue 3. 1996-01-11. PMID:7493050. |
porcine aortic endothelial cells were incubated for six hours in the presence of 60 microm unmodified hemoglobin (hba0), hemoglobin cross-linked between the alpha chains with bis-(3,5-dibromosalicyl) fumarate (alpha alpha hb) or cyanomet-alpha alpha-hemoglobin (cnmet alpha alpha hb). |
1996-01-11 |
2023-08-12 |
Not clear |
| R Motterlini, R Foresti, K Vandegriff, R M Winslo. The autoxidation of alpha alpha cross-linked hemoglobin: a possible role in the oxidative stress to endothelium. Artificial cells, blood substitutes, and immobilization biotechnology. vol 23. issue 3. 1996-01-11. PMID:7493050. |
microsomal ho content increased 4.1-fold in the presence of alpha alpha hb, 2.7-fold with hba0 and 1.8-fold with cnmet alpha alpha hb over the control value. |
1996-01-11 |
2023-08-12 |
Not clear |
| R Motterlini, R Foresti, K Vandegriff, R M Winslo. The autoxidation of alpha alpha cross-linked hemoglobin: a possible role in the oxidative stress to endothelium. Artificial cells, blood substitutes, and immobilization biotechnology. vol 23. issue 3. 1996-01-11. PMID:7493050. |
the rates of methemoglobin formation exhibited a linear relationship over the time of incubation (r = 0.94) and the apparent rate constant was 1.8-fold higher for alpha alpha hb (0.023 h-1) than hba0 (0.013 h-1). |
1996-01-11 |
2023-08-12 |
Not clear |
| R Motterlini, R Foresti, K Vandegriff, R M Winslo. The autoxidation of alpha alpha cross-linked hemoglobin: a possible role in the oxidative stress to endothelium. Artificial cells, blood substitutes, and immobilization biotechnology. vol 23. issue 3. 1996-01-11. PMID:7493050. |
when cells were incubated with 100% methemoglobin, ho activity increased 5.0-fold and 4.7-fold for hba0 and alpha alpha hb, respectively. |
1996-01-11 |
2023-08-12 |
Not clear |
| R Motterlini, R Foresti, K Vandegriff, R M Winslo. The autoxidation of alpha alpha cross-linked hemoglobin: a possible role in the oxidative stress to endothelium. Artificial cells, blood substitutes, and immobilization biotechnology. vol 23. issue 3. 1996-01-11. PMID:7493050. |
intracellular heme concentration, measured after 24 hours of incubation, was also significantly greater in the presence of alpha alpha hb (52.6% over baseline) compared to hba0 (10.8%) and cnmet alpha alpha hb (15.3%) groups (p < 0.05). |
1996-01-11 |
2023-08-12 |
Not clear |