| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Tan, J S Tay, Y C Wong, S K Kham, N Bte Abd Aziz, S H Teo, H B Won. Molecular analysis of Hb Q-H disease and Hb Q-Hb E in a Singaporean family. The Southeast Asian journal of tropical medicine and public health. vol 26 Suppl 1. 1996-06-26. PMID:8629117. |
cellulose acetate electrophoresis of the father's blood showed the presence of hb a, f and e. molecular analysis of the father's dna confirmed an intact set of alpha-genes (alpha alpha/alpha alpha). |
1996-06-26 |
2023-08-12 |
Not clear |
| K Torcharus, T Sriphaisal, T Krutvecho, C Suwanasophon, J Intarapakawon. Clinical phenotypes and genotypes diagnosis of thalassemia in children. The Southeast Asian journal of tropical medicine and public health. vol 26 Suppl 1. 1996-06-26. PMID:8629123. |
alpha and beta thalassemia, hemoglobin (hb) e, and hb constant spring (cs) are prevalent in thailand. |
1996-06-26 |
2023-08-12 |
Not clear |
| N S Smetanina, J Y Leonova, N Levy, T H Huisma. The alpha / beta and alpha 2 / alpha 1-globin mRNA ratios in different forms of alpha-thalassemia. Biochimica et biophysica acta. vol 1315. issue 3. 1996-06-04. PMID:8611658. |
the father carried the 4.2 kb deletion on one chromosome and a taa --> caa mutation at the terminating codon of the alpha 2 gene (hb constant spring or cs) on the other chromosome. |
1996-06-04 |
2023-08-12 |
Not clear |
| N S Smetanina, J Y Leonova, N Levy, T H Huisma. The alpha / beta and alpha 2 / alpha 1-globin mRNA ratios in different forms of alpha-thalassemia. Biochimica et biophysica acta. vol 1315. issue 3. 1996-06-04. PMID:8611658. |
the mother had the 3.7 kb deletion on one chromosome and a ta a --> tat mutation at the terminating codon of the alpha 2-globin gene (hb paksé) of the second chromosome. |
1996-06-04 |
2023-08-12 |
Not clear |
| N S Smetanina, J Y Leonova, N Levy, T H Huisma. The alpha / beta and alpha 2 / alpha 1-globin mRNA ratios in different forms of alpha-thalassemia. Biochimica et biophysica acta. vol 1315. issue 3. 1996-06-04. PMID:8611658. |
the results confirm the importance of the alpha 2 alpha 1-mrna for the synthesis of alpha chains in alpha-thalassemia-2 homozygotes (-alpha/-alpha) and in patients with hb h disease due to the deletion of three alpha-globin genes (-alpha/--). |
1996-06-04 |
2023-08-12 |
Not clear |
| N S Smetanina, J Y Leonova, N Levy, T H Huisma. The alpha / beta and alpha 2 / alpha 1-globin mRNA ratios in different forms of alpha-thalassemia. Biochimica et biophysica acta. vol 1315. issue 3. 1996-06-04. PMID:8611658. |
furthermore, the mrna production of the alpha 1-globin gene on the chromosome with the alpha cs mutation (alpha cs alpha) is only one-half of that by the alpha 2 alpha 1-globin gene of a chromosome with a 3.7 or 4.2 kb deletion, explaining the greater severity of, and higher hb h level in hb h patients with the alpha cs alpha condition (alpha cs alpha/--) as compared to those with the three gene deletion (-alpha/--). |
1996-06-04 |
2023-08-12 |
Not clear |
| K Adachi, J Pang, P Konitzer, S Surre. Polymerization of recombinant hemoglobin F gamma E6V and hemoglobin F gamma E6V, gamma Q87T alone, and in mixtures with hemoglobin S. Blood. vol 87. issue 4. 1996-05-29. PMID:8608256. |
these results suggest that gin-gamma 87 is a critical amino acid for exclusion of fs hybrids (alpha 2 beta s gamma) from nuclei formation with hb s. our findings also show that val-gamma 6 in hybrids that form in mixtures of the hb f variants with either hb s or hb a interacts with the hydrophobic acceptor pocket on the ef helix of an adjacent tetramer containing thr-beta 87. |
1996-05-29 |
2023-08-12 |
Not clear |
| E Kanavakis, J Traeger-Synodinos, I Papasotiriou, C Vrettou, A Metaxotou-Mavromati, A Stamoulakatou, E Lagona, C Kattami. The interaction of alpha zero thalassaemia with Hb Icaria: three unusual cases of haemoglobinopathy H. British journal of haematology. vol 92. issue 2. 1996-05-15. PMID:8602995. |
the interaction of alpha zero thalassaemia with hb icaria: three unusual cases of haemoglobinopathy h. the clinical, haematological, biosynthetic and molecular data of three greek haemoglobin h (hbh) disease patients with a distinctive clinical phenotype are described. |
1996-05-15 |
2023-08-12 |
Not clear |
| E Kanavakis, J Traeger-Synodinos, I Papasotiriou, C Vrettou, A Metaxotou-Mavromati, A Stamoulakatou, E Lagona, C Kattami. The interaction of alpha zero thalassaemia with Hb Icaria: three unusual cases of haemoglobinopathy H. British journal of haematology. vol 92. issue 2. 1996-05-15. PMID:8602995. |
this observation should be considered carefully when giving genetic counselling to families carrying the rare hb icaria mutation and an alpha zero thalassaemia mutation. |
1996-05-15 |
2023-08-12 |
Not clear |
| A Takats. [Sudden unexpected natural death from a viewpoint of forensic pathology]. Nihon hoigaku zasshi = The Japanese journal of legal medicine. vol 49. issue 6. 1996-03-15. PMID:8583687. |
parameters included in the last type, which is a useful tool for speculation of antemortem pathophysiology were t-bil, ttt, ztt, bun, cre, ua, alpha 1- and beta 2-microglobin, t-chol, gha1c, tp, a/g, hb and hct. |
1996-03-15 |
2023-08-12 |
Not clear |
| H Kosaka, A Seiyam. Physiological role of nitric oxide as an enhancer of oxygen transfer from erythrocytes to tissues. Biochemical and biophysical research communications. vol 218. issue 3. 1996-03-12. PMID:8579585. |
the present study revealed the physiological role of no as an enhancer of oxygen release from erythrocytes to peripheral tissue by breaking or stretching the heme iron-proximal histidine bond in the alpha subunit of hemoglobin (hb), while maintaining oxygen binding capacity by restoring the bond in the lungs. |
1996-03-12 |
2023-08-12 |
Not clear |
| H Kosaka, A Seiyam. Physiological role of nitric oxide as an enhancer of oxygen transfer from erythrocytes to tissues. Biochemical and biophysical research communications. vol 218. issue 3. 1996-03-12. PMID:8579585. |
oxygen affinity was significantly decreased in blood containing no-bound hb alpha. |
1996-03-12 |
2023-08-12 |
Not clear |
| B Landin, S Berglund, K Wallma. Two different mutations in codon 97 of the beta-globin gene cause Hb Malmö in Sweden. American journal of hematology. vol 51. issue 1. 1996-03-04. PMID:8571935. |
an abnormal hemoglobin with increased oxygen affinity, hb malmö [alpha 2 beta 297(fg4)his-->gln], was found to cause erythrocytosis in two apparently unrelated swedish families. |
1996-03-04 |
2023-08-12 |
Not clear |
| S Fucharoen, N Siritanaratkul, P Winichagoon, J Chowthaworn, W Siriboon, W Muangsup, S Chaicharoen, N Poolsup, B Chindavijak, P Pootrakul, A Piankijagum, A N Schechter, G P Rodger. Hydroxyurea increases hemoglobin F levels and improves the effectiveness of erythropoiesis in beta-thalassemia/hemoglobin E disease. Blood. vol 87. issue 3. 1996-03-01. PMID:8562958. |
complete blood counts including reticulocyte counts, amounts of hb e and hb f, g gamma:a gamma and alpha:non-alpha globin biosynthetic ratios were evaluated before and during treatment. |
1996-03-01 |
2023-08-12 |
Not clear |
| S Fucharoen, N Siritanaratkul, P Winichagoon, J Chowthaworn, W Siriboon, W Muangsup, S Chaicharoen, N Poolsup, B Chindavijak, P Pootrakul, A Piankijagum, A N Schechter, G P Rodger. Hydroxyurea increases hemoglobin F levels and improves the effectiveness of erythropoiesis in beta-thalassemia/hemoglobin E disease. Blood. vol 87. issue 3. 1996-03-01. PMID:8562958. |
we conclude that increased hb f production in beta-thalassemia/hb e patients, with an improvement in the alpha:non-alpha globin ratios and, probably, the effectiveness of erythropoiesis, can be achieved using hu. |
1996-03-01 |
2023-08-12 |
Not clear |
| M Kosh. Sickle cell disease and pregnancy. Blood reviews. vol 9. issue 3. 1996-03-01. PMID:8563517. |
sickle cell disease refers to a group of genetic disorders characterised by the predominance of hemoglobin s. this includes sickle cell anemia (ss) sickle hemoglobin c disease (sc), sickle beta thalassemia plus (s beta + thal), sickle beta thalassemia zero (beta zero thal), sickle with alpha thalassemia (ss alpha thal) and rare combinations of sickle hemoglobin with hb d, hb o, etc. |
1996-03-01 |
2023-08-12 |
Not clear |
| F Morlé, A Francina, R Ducrocq, H Wajcman, C Gonnet, N Philippe, G Souillet, J Gode. A new alpha chain variant Hb Sallanches [alpha 2 104(G11) Cys-->Tyr] associated with HbH disease in one homozygous patient. British journal of haematology. vol 91. issue 3. 1996-02-23. PMID:8555062. |
a new alpha chain variant hb sallanches [alpha 2 104(g11) cys-->tyr] associated with hbh disease in one homozygous patient. |
1996-02-23 |
2023-08-12 |
Not clear |
| S B Olsen, D B Tang, M R Jackson, E R Gomez, B Ayala, B M Alvin. Enhancement of platelet deposition by cross-linked hemoglobin in a rat carotid endarterectomy model. Circulation. vol 93. issue 2. 1996-02-20. PMID:8548906. |
we postulated that binding of no by cross-linked hemoglobin (alpha alpha hb) could also increase platelet deposition at sites of subintimal injury. |
1996-02-20 |
2023-08-12 |
human |
| A Qualtieri, E V De Marco, L Crescibene, V Andreoli, A Bagalà, M Scornalenchi, C Brancatl, C M Grec. Hb J-Wenchang-Wuming or alpha 11(A9)Lys-->Gln in an Italian woman. Hemoglobin. vol 19. issue 5. 1996-02-05. PMID:8537231. |
hb j-wenchang-wuming or alpha 11(a9)lys-->gln in an italian woman. |
1996-02-05 |
2023-08-12 |
Not clear |
| H Wajcman, Y Blouquit, A Lahary, A M Soummer, P Groff, J Bardakdjian, C Préhu, J Riou, C Godard, F Galactèro. Three new neutral alpha chain variants: Hb Bois Guillaume [alpha 65(E14(Ala-->Val], Hb Mantes-la-Jolie [alpha 79(EF8)Ala-Thr], and Hb Mosella [alpha 111(G18)Ala-->Thr]. Hemoglobin. vol 19. issue 5. 1996-02-05. PMID:8537232. |
three new neutral alpha chain variants: hb bois guillaume [alpha 65(e14(ala-->val], hb mantes-la-jolie [alpha 79(ef8)ala-thr], and hb mosella [alpha 111(g18)ala-->thr]. |
1996-02-05 |
2023-08-12 |
Not clear |