| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Maxime Dahan, Sabine Lévi, Camilla Luccardini, Philippe Rostaing, Béatrice Riveau, Antoine Trille. Diffusion dynamics of glycine receptors revealed by single-quantum dot tracking. Science (New York, N.Y.). vol 302. issue 5644. 2003-11-06. PMID:14564008. |
we used qds to track individual glycine receptors (glyrs) and analyze their lateral dynamics in the neuronal membrane of living cells for periods ranging from milliseconds to minutes. |
2003-11-06 |
2023-08-12 |
Not clear |
| Geoffrey S Findlay, Rachel Phelan, Michael T Roberts, Gregg E Homanics, Susan E Bergeson, Gregory F Lopreato, S John Mihic, Yuri A Blednov, R Adron Harri. Glycine receptor knock-in mice and hyperekplexia-like phenotypes: comparisons with the null mutant. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 22. 2003-10-02. PMID:12954867. |
strychnine-sensitive glycine receptors (glyrs) inhibit neurotransmission in the spinal cord and brainstem. |
2003-10-02 |
2023-08-12 |
mouse |
| Gonzalo E Yevenes, Robert W Peoples, Juan C Tapia, Jorge Parodi, Ximena Soto, Juan Olate, Luis G Aguay. Modulation of glycine-activated ion channel function by G-protein betagamma subunits. Nature neuroscience. vol 6. issue 8. 2003-09-23. PMID:12858180. |
glycine receptors (glyrs), together with gaba(a) and nicotinic acetylcholine (ach) receptors, form part of the ligand-activated ion channel superfamily and regulate the excitability of the mammalian brain stem and spinal cord. |
2003-09-23 |
2023-08-12 |
Not clear |
| Gonzalo E Yevenes, Robert W Peoples, Juan C Tapia, Jorge Parodi, Ximena Soto, Juan Olate, Luis G Aguay. Modulation of glycine-activated ion channel function by G-protein betagamma subunits. Nature neuroscience. vol 6. issue 8. 2003-09-23. PMID:12858180. |
here we report that the ability of the neurotransmitter glycine to gate recombinant and native ionotropic glyrs is modulated by the g protein betagamma dimer (gbetagamma). |
2003-09-23 |
2023-08-12 |
Not clear |
| Liu Lin Thio, Ananth Shanmugam, Keith Isenberg, Kelvin Yamad. Benzodiazepines block alpha2-containing inhibitory glycine receptors in embryonic mouse hippocampal neurons. Journal of neurophysiology. vol 90. issue 1. 2003-09-12. PMID:12660352. |
inhibitory glycine receptors (glyrs) in the mammalian cortex probably contribute to brain development and to maintaining tonic inhibition. |
2003-09-12 |
2023-08-12 |
mouse |
| Daryl L Davies, James R Trudell, S John Mihic, Daniel K Crawford, Ronald L Alkan. Ethanol potentiation of glycine receptors expressed in Xenopus oocytes antagonized by increased atmospheric pressure. Alcoholism, clinical and experimental research. vol 27. issue 5. 2003-08-29. PMID:12766618. |
the current study begins to test the hypothesis that ethanol acts by a common mechanism on ligand-gated ion channels by expanding previous hyperbaric investigations on gamma-aminobutyric acid type a (gaba(a)) receptors (gaba(a)rs) at the biochemical level to alpha(1)glycine (glyrs) expressed in xenopus oocytes. |
2003-08-29 |
2023-08-12 |
xenopus_laevis |
| Udo Kraushaar, Kurt H Backu. Characterization of GABA(A) and glycine receptors in neurons of the developing rat inferior colliculus. Pflugers Archiv : European journal of physiology. vol 445. issue 2. 2003-07-29. PMID:12457249. |
gaba(a) receptors (gaba(a)rs) and glycine receptors (glyrs) expressed in developing neurons (p3-8) of the rat inferior colliculus (ic) were investigated using fast application of transmitters on nucleated patches and whole-cell patch-clamp recordings. |
2003-07-29 |
2023-08-12 |
rat |
| Siriporn C Chattipakorn, Lori L McMaho. Strychnine-sensitive glycine receptors depress hyperexcitability in rat dentate gyrus. Journal of neurophysiology. vol 89. issue 3. 2003-05-09. PMID:12612034. |
we now report that glycine application to dentate granule cells and hilar interneurons recorded in acute slices from adolescent rats elicits a strychnine-sensitive current similar to glycine-mediated currents recorded in area ca1, indicating that glyrs are also present on neurons in the dentate gyrus. |
2003-05-09 |
2023-08-12 |
rat |
| Siriporn C Chattipakorn, Lori L McMaho. Strychnine-sensitive glycine receptors depress hyperexcitability in rat dentate gyrus. Journal of neurophysiology. vol 89. issue 3. 2003-05-09. PMID:12612034. |
these results demonstrate that glycine, acting at glyrs, elicits neuronal inhibition in dentate. |
2003-05-09 |
2023-08-12 |
rat |
| Yannick Grosskreutz, Heinrich Betz, Matthias Kneusse. Rescue of molybdenum cofactor biosynthesis in gephyrin-deficient mice by a Cnx1 transgene. Biochemical and biophysical research communications. vol 301. issue 2. 2003-04-15. PMID:12565882. |
mice deficient in gephyrin die early postnatally and display a loss of glycine receptors (glyrs) and many gaba(a) receptor (gaba(a)r) subtypes from postsynaptic sites. |
2003-04-15 |
2023-08-12 |
mouse |
| b' G\\xc3\\xa1bor Maksay, T\\xc3\\xadmea B\\xc3\\xadr\\xc3\\xb. Dual cooperative allosteric modulation of binding to ionotropic glycine receptors. Neuropharmacology. vol 43. issue 7. 2003-03-21. PMID:12504915.' |
glycine receptors (glyrs) were studied via [(3)h]strychnine binding to synaptosomal membranes of rat spinal cord. |
2003-03-21 |
2023-08-12 |
rat |
| b' G\\xc3\\xa1bor Maksay, T\\xc3\\xadmea B\\xc3\\xadr\\xc3\\xb. Dual cooperative allosteric modulation of binding to ionotropic glycine receptors. Neuropharmacology. vol 43. issue 7. 2003-03-21. PMID:12504915.' |
combined inhibitory effects of the allosteric agents suggest that there are different subgroups (tropeines, alcohols and dihydropyridines) binding to distinct sites on glyrs exerting cooperativity with glycine via a common mechanism. |
2003-03-21 |
2023-08-12 |
rat |
| J M Mangin, A Guyon, D Eugène, D Paupardin-Tritsch, P Legendr. Functional glycine receptor maturation in the absence of glycinergic input in dopaminergic neurones of the rat substantia nigra. The Journal of physiology. vol 542. issue Pt 3. 2003-02-13. PMID:12154171. |
the postnatal maturation pattern of glycine receptor channels (glyrs) expressed by dopaminergic (da) neurones of the rat substantia nigra pars compacta (snc) was investigated using single-channel and whole-cell patch-clamp recordings in brain slices from rats aged 7-21 postnatal days (p). |
2003-02-13 |
2023-08-12 |
rat |
| Jochen Meier, René Jüttner, Sergei Kirischuk, Rosemarie Granty. Synaptic anchoring of glycine receptors in developing collicular neurons under control of metabotropic glutamate receptor activity. Molecular and cellular neurosciences. vol 21. issue 2. 2003-01-07. PMID:12401451. |
in the absence of kcc2 and glutamatergic transmission, newborn viaat-labeled boutons contained glyt2, released glycine, and accumulated postsynaptic gephyrin and glyrs. |
2003-01-07 |
2023-08-12 |
Not clear |
| Bodo Laub. Potentiation of inhibitory glycinergic neurotransmission by Zn2+: a synergistic interplay between presynaptic P2X2 and postsynaptic glycine receptors. The European journal of neuroscience. vol 16. issue 6. 2002-12-04. PMID:12383231. |
the divalent cation zinc is known to modulate chloride currents carried by native and recombinant mammalian glycine receptors (glyrs). |
2002-12-04 |
2023-08-12 |
rat |
| Bodo Laube, Gábor Maksay, Rudolf Schemm, Heinrich Bet. Modulation of glycine receptor function: a novel approach for therapeutic intervention at inhibitory synapses? Trends in pharmacological sciences. vol 23. issue 11. 2002-11-26. PMID:12413807. |
inhibitory glycine receptors (glyrs) are members of the nicotinic acetylcholine receptor superfamily and inhibit neuronal firing by opening cl(-) channels following agonist binding. |
2002-11-26 |
2023-08-12 |
Not clear |
| Andrew J Moorhouse, Angelo Keramidas, Andrey Zaykin, Peter R Schofield, Peter H Barr. Single channel analysis of conductance and rectification in cation-selective, mutant glycine receptor channels. The Journal of general physiology. vol 119. issue 5. 2002-11-04. PMID:11981021. |
in this study, we investigate the molecular determinants and mechanisms of ion permeation and ion charge selectivity in this family of channels by characterizing the single channel conductance and rectification of alpha1 homomeric human glycine receptor channels (glyrs) containing pore mutations that impart cation selectivity. |
2002-11-04 |
2023-08-12 |
human |
| Michaël Russier, Irina L Kopysova, Norbert Ankri, Nadine Ferrand, Dominique Debann. GABA and glycine co-release optimizes functional inhibition in rat brainstem motoneurons in vitro. The Journal of physiology. vol 541. issue Pt 1. 2002-10-21. PMID:12015425. |
three types of mipsc were distinguished according to their kinetics and their sensitivity to receptor antagonists: faster decaying events mediated by glycine receptors (glyrs), slower decaying events mediated by gaba(a) receptors (gaba(a)rs), and mipscs displaying two components corresponding to gaba and glycine co-release. |
2002-10-21 |
2023-08-12 |
rat |
| Gábor Maksay, Tímea Bíró, Bodo Laub. Hyperekplexia mutation of glycine receptors: decreased gating efficacy with altered binding thermodynamics. Biochemical pharmacology. vol 64. issue 2. 2002-08-16. PMID:12123749. |
[(3)h]strychnine binding was studied to recombinant human alpha(1) and the hyperekplexia mutant alpha(1)r271l glycine receptors (glyrs) transiently expressed in human embryonic kidney (hek)-293 cell cultures at 0, 18 and 37 degrees. |
2002-08-16 |
2023-08-12 |
human |
| Gábor Maksay, Tímea Bíró, Bodo Laub. Hyperekplexia mutation of glycine receptors: decreased gating efficacy with altered binding thermodynamics. Biochemical pharmacology. vol 64. issue 2. 2002-08-16. PMID:12123749. |
the inhibition constants of the agonist glycine showed opposite temperature dependence on alpha(1) glyrs, corresponding to endothermic binding driven by large entropic increases. |
2002-08-16 |
2023-08-12 |
human |