| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ping Li, Malcolm Slaughte. Glycine receptor subunit composition alters the action of GABA antagonists. Visual neuroscience. vol 24. issue 4. 2007-11-20. PMID:17659095. |
gaba receptor antagonists produce an unexpectedly significant inhibition of native glycine receptors in retina and in alpha1 or alpha2 homomeric glycine receptors (glyrs) expressed in hek 293 cells. |
2007-11-20 |
2023-08-12 |
Not clear |
| Zhe Yang, Brett A Cromer, Robert J Harvey, Michael W Parker, Joseph W Lync. A proposed structural basis for picrotoxinin and picrotin binding in the glycine receptor pore. Journal of neurochemistry. vol 103. issue 2. 2007-11-20. PMID:17714449. |
picrotoxin, an antagonist of structurally-rated gaba(a) receptors (gaba(a)rs) and glycine receptors (glyrs), is an equimolar mixture of picrotoxinin (ptxinin) and picrotin (ptn). |
2007-11-20 |
2023-08-12 |
Not clear |
| Daniel K Crawford, James R Trudell, Edward J Bertaccini, Kaixun Li, Daryl L Davies, Ronald L Alkan. Evidence that ethanol acts on a target in Loop 2 of the extracellular domain of alpha1 glycine receptors. Journal of neurochemistry. vol 102. issue 6. 2007-10-19. PMID:17561937. |
considerable evidence indicates that ethanol acts on specific residues in the transmembrane domains of glycine receptors (glyrs). |
2007-10-19 |
2023-08-12 |
xenopus_laevis |
| N M Iatsenko, T Sh Tsintsadze, N O Lozov. [The synthetic cannabinoid analog WIN 55,212-2 potentiates the amplitudes of glycine-activated currents]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994). vol 53. issue 3. 2007-09-27. PMID:17725041. |
the effects of win 55,212-2 on i(gly) were not attenuated in the presence of cb1 receptor antagonist am251, suggesting that cb1 receptor activation are not involved in action of cannabinoid on glyrs. |
2007-09-27 |
2023-08-12 |
Not clear |
| Dian-Shi Wang, Roeland Buckinx, Hervé Lecorronc, Jean-Marie Mangin, Jean-Michel Rigo, Pascal Legendr. Mechanisms for picrotoxinin and picrotin blocks of alpha2 homomeric glycine receptors. The Journal of biological chemistry. vol 282. issue 22. 2007-07-19. PMID:17405877. |
contrary to its effect on the gamma-aminobutyric acid type a and c receptors, picrotoxin antagonism of the alpha1 homomeric glycine receptors (glyrs) has been shown to be non-use-dependent and nonselective between the picrotoxin components picrotoxinin and picrotin. |
2007-07-19 |
2023-08-12 |
Not clear |
| Matthias Kneussel, Sven Loebric. Trafficking and synaptic anchoring of ionotropic inhibitory neurotransmitter receptors. Biology of the cell. vol 99. issue 6. 2007-06-28. PMID:17504238. |
gaba(a)rs (gamma-aminobutyric type a receptors) and glyrs (glycine receptors) are the major inhibitory receptors in the central nervous system. |
2007-06-28 |
2023-08-12 |
human |
| Anna Molander, Helga Höifödt Lidö, Elin Löf, Mia Ericson, Bo Söderpal. The glycine reuptake inhibitor Org 25935 decreases ethanol intake and preference in male wistar rats. Alcohol and alcoholism (Oxford, Oxfordshire). vol 42. issue 1. 2007-06-26. PMID:17098748. |
previous findings from our group indicate that accumbal glycine receptors (glyrs) are involved in mediating the dopamine (da) activating effects of ethanol (etoh), and that administration of glycine locally into the nucleus accumbens (nac) reduces etoh consumption in etoh high-preferring rats. |
2007-06-26 |
2023-08-12 |
rat |
| b' S Buldakova, E Real, Y Jakob, P Brezhestovski\\xc4\\xa. [Ca-dependent modulation of human glycine receptors expressed in cultured cell lines]. Tsitologiia. vol 49. issue 1. 2007-06-26. PMID:17432611.' |
glycine receptors (glyrs) provide the main inhibitory neurotransmission in spinal cord and brainstem synapses of vertebrates. |
2007-06-26 |
2023-08-12 |
human |
| Henry J Waldvogel, Kristin Baer, Kathryn L Allen, Mark I Rees, Richard L M Faul. Glycine receptors in the striatum, globus pallidus, and substantia nigra of the human brain: an immunohistochemical study. The Journal of comparative neurology. vol 502. issue 6. 2007-06-26. PMID:17444490. |
glycine receptors (glyrs) are heteropentameric chloride ion channels that facilitate fast-response, inhibitory neurotransmission in the mammalian spinal cord and brain. |
2007-06-26 |
2023-08-12 |
human |
| M A Carrasco, P A Castro, F J Sepulveda, M Cuevas, J C Tapia, P Izaurieta, B van Zundert, L G Aguay. Anti-homeostatic synaptic plasticity of glycine receptor function after chronic strychnine in developing cultured mouse spinal neurons. Journal of neurochemistry. vol 100. issue 5. 2007-04-02. PMID:17217420. |
after chronic blockade of glycine receptors (glyrs), the frequency of synaptic transmission showed a significant enhancement demonstrating the phenomenon of anti-homeostatic plasticity. |
2007-04-02 |
2023-08-12 |
mouse |
| Charlotte Förster, Markus Perbandt, Arnd B E Brauer, Svenja Brode, Jens P Fürste, Christian Betzel, Volker A Erdman. Crystallization and preliminary X-ray diffraction analysis of an Escherichia coli tRNA(Gly) acceptor-stem microhelix. Acta crystallographica. Section F, Structural biology and crystallization communications. vol 63. issue Pt 1. 2007-02-06. PMID:17183173. |
the trna(gly) and glycyl-trna synthetase (glyrs) system is an evolutionary special case within the class ii aminoacyl-trna synthetases because two divergent types of glyrs exist: an archaebacterial/human type and an eubacterial type. |
2007-02-06 |
2023-08-12 |
Not clear |
| Ingo Paarmann, Bertram Schmitt, Björn Meyer, Michael Karas, Heinrich Bet. Mass spectrometric analysis of glycine receptor-associated gephyrin splice variants. The Journal of biological chemistry. vol 281. issue 46. 2007-01-18. PMID:17001074. |
gephyrin is an ubiquitously expressed protein that, in the nervous system, is essential for synaptic anchoring of glycine receptors (glyrs) and major gabaa receptor subtypes. |
2007-01-18 |
2023-08-12 |
mouse |
| Zhenglan Chen, Glenn H Dillon, Renqi Huan. Identification of residues critical for Cu2+-mediated inhibition of glycine alpha1 receptors. Neuropharmacology. vol 51. issue 4. 2006-11-06. PMID:16842826. |
endogenous divalent cations cu2+ and zn2+ suppress the activity of glycine receptors (glyrs). |
2006-11-06 |
2023-08-12 |
human |
| Weifeng Song, Siriporn C Chattipakorn, Lori L McMaho. Glycine-gated chloride channels depress synaptic transmission in rat hippocampus. Journal of neurophysiology. vol 95. issue 4. 2006-09-25. PMID:16381810. |
using whole cell current-clamp recordings, we show that activation of strychnine-sensitive glyrs through exogenous glycine application causes a significant decrease in input resistance and prevents somatically generated action potentials in both ca1 pyramidal cells and interneurons. |
2006-09-25 |
2023-08-12 |
rat |
| Lily Vitanov. Immunocytochemical study of glycine receptors in the retina of the frog Xenopus laevis. Anatomy and embryology. vol 211. issue 3. 2006-09-21. PMID:16416306. |
glycine receptors (glyrs), as revealed by means of several different antibodies, were mainly distributed in the inner (ipl) and the outer plexiform layers. |
2006-09-21 |
2023-08-12 |
xenopus_laevis |
| Heinrich Betz, Bodo Laub. Glycine receptors: recent insights into their structural organization and functional diversity. Journal of neurochemistry. vol 97. issue 6. 2006-08-11. PMID:16805771. |
strychnine-sensitive glycine receptors (glyrs) are known to mediate synaptic inhibition in spinal cord, brainstem and other regions of the cns. |
2006-08-11 |
2023-08-12 |
Not clear |
| Aaron J Camp, Robert J Callister, Alan M Bricht. Inhibitory synaptic transmission differs in mouse type A and B medial vestibular nucleus neurons in vitro. Journal of neurophysiology. vol 95. issue 5. 2006-06-28. PMID:16407430. |
fast inhibitory synaptic transmission in the medial vestibular nucleus (mvn) is mediated by gaba(a) receptors (gaba(a)rs) and glycine receptors (glyrs). |
2006-06-28 |
2023-08-12 |
mouse |
| Long-Hua Zhang, Lin Xu, Tian-Le X. Glycine receptor activation regulates short-term plasticity in CA1 area of hippocampal slices of rats. Biochemical and biophysical research communications. vol 344. issue 3. 2006-06-22. PMID:16631121. |
functional glycine receptors (glyrs) are enriched in the hippocampus, but their roles in synaptic transmission are unclear. |
2006-06-22 |
2023-08-12 |
rat |
| Elena Ivanova, Ulrike Müller, Heinz Wässl. Characterization of the glycinergic input to bipolar cells of the mouse retina. The European journal of neuroscience. vol 23. issue 2. 2006-04-25. PMID:16420443. |
here we evaluated the functional properties and subunit composition of glycine receptors (glyrs) in bipolar cells. |
2006-04-25 |
2023-08-12 |
mouse |
| Christoph Maas, Nadia Tagnaouti, Sven Loebrich, Bardo Behrend, Corinna Lappe-Siefke, Matthias Kneusse. Neuronal cotransport of glycine receptor and the scaffold protein gephyrin. The Journal of cell biology. vol 172. issue 3. 2006-04-25. PMID:16449194. |
gephyrin, which is a multimeric scaffold protein, interacts with cytoskeletal elements and stabilizes glycine receptors (glyrs) and individual subtypes of gamma-aminobutyric acid a receptors at inhibitory postsynaptic sites. |
2006-04-25 |
2023-08-12 |
Not clear |