| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N B Jørgensen, S H Jacobsen, C Dirksen, K N Bojsen-Møller, L Naver, L Hvolris, T R Clausen, B S Wulff, D Worm, D Lindqvist Hansen, S Madsbad, J J Hols. Acute and long-term effects of Roux-en-Y gastric bypass on glucose metabolism in subjects with Type 2 diabetes and normal glucose tolerance. American journal of physiology. Endocrinology and metabolism. vol 303. issue 1. 2012-09-10. PMID:22535748. |
glucose, insulin, c-peptide, glucagon-like peptide-1 (glp-1), glucose-dependent-insulinotropic polypeptide (gip), and glucagon concentrations were measured. |
2012-09-10 |
2023-08-12 |
human |
| A P Gjesing, C T Ekstrøm, H Eiberg, S A Urhammer, J J Holst, O Pedersen, T Hanse. Fasting and oral glucose-stimulated levels of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are highly familial traits. Diabetologia. vol 55. issue 5. 2012-08-24. PMID:22349073. |
therefore, the objective of this study was to investigate the familiality of fasting and stimulated measures of plasma glucose, serum insulin, serum c-peptide, plasma glucose-dependent insulinotropic polypeptide (gip) and plasma glucagon-like peptide-1 (glp-1) among non-diabetic relatives of danish type 2 diabetic patients. |
2012-08-24 |
2023-08-12 |
Not clear |
| Anita Mofidi, Zachary M Ferraro, Katherine A Stewart, Hilary M F Tulk, Lindsay E Robinson, Alison M Duncan, Terry E Graha. The acute impact of ingestion of sourdough and whole-grain breads on blood glucose, insulin, and incretins in overweight and obese men. Journal of nutrition and metabolism. vol 2012. 2012-08-23. PMID:22474577. |
in a randomized, crossover study, overweight or obese males ingested 11-grain, sprouted-grain, 12-grain, sourdough, or white bread on different occasions, matched for available carbohydrate (50 g) in part 1 (n = 12) and bread mass (107 g) in part 2 (n = 11), and blood glucose, insulin and glucose-dependent insulinotropic polypeptide (gip) and glucagon-like peptide-1 (glp-1) were determined for 3 h. |
2012-08-23 |
2023-08-12 |
human |
| Yaohui Nie, Ronald C Ma, Juliana C N Chan, Haiyan Xu, Gang X. Glucose-dependent insulinotropic peptide impairs insulin signaling via inducing adipocyte inflammation in glucose-dependent insulinotropic peptide receptor-overexpressing adipocytes. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 26. issue 6. 2012-08-20. PMID:22366643. |
glucose-dependent insulinotropic peptide (gip) exerts multiple biological effects via the g-protein-coupled receptor gipr, including glucose-stimulated insulin production and secretion, cell proliferation, and antiapoptosis in pancreatic β-cells. |
2012-08-20 |
2023-08-12 |
mouse |
| Yaohui Nie, Ronald C Ma, Juliana C N Chan, Haiyan Xu, Gang X. Glucose-dependent insulinotropic peptide impairs insulin signaling via inducing adipocyte inflammation in glucose-dependent insulinotropic peptide receptor-overexpressing adipocytes. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 26. issue 6. 2012-08-20. PMID:22366643. |
our results suggest that gip might be one of the stimuli attributable to obesity-induced insulin resistance via the induction of adipocyte inflammation. |
2012-08-20 |
2023-08-12 |
mouse |
| Christine M A Martin, Victor A Gault, Stephen McClean, Peter R Flatt, Nigel Irwi. Degradation, insulin secretion, glucose-lowering and GIP additive actions of a palmitate-derivatised analogue of xenin-25. Biochemical pharmacology. vol 84. issue 3. 2012-08-14. PMID:22561048. |
degradation, insulin secretion, glucose-lowering and gip additive actions of a palmitate-derivatised analogue of xenin-25. |
2012-08-14 |
2023-08-12 |
mouse |
| Christine M A Martin, Victor A Gault, Stephen McClean, Peter R Flatt, Nigel Irwi. Degradation, insulin secretion, glucose-lowering and GIP additive actions of a palmitate-derivatised analogue of xenin-25. Biochemical pharmacology. vol 84. issue 3. 2012-08-14. PMID:22561048. |
insulinotropic responses of xenin-25(lys(13)pal) in clonal beta-cells were similar to native xenin-25, moreover xenin-25(lys(13)pal) significantly (p<0.05 to p<0.001) potentiated the insulin releasing action of (d-ala(2))gip. |
2012-08-14 |
2023-08-12 |
mouse |
| David Porter, Emilie Faivre, Peter R Flatt, Christian Hölscher, Victor A Gaul. Actions of incretin metabolites on locomotor activity, cognitive function and in vivo hippocampal synaptic plasticity in high fat fed mice. Peptides. vol 35. issue 1. 2012-08-07. PMID:22465882. |
therefore, the present study investigated effects of glp-1(9-36)amide and gip(3-42) on locomotor activity, cognitive function and hippocampal synaptic plasticity in mice with diet-induced obesity and insulin resistance. |
2012-08-07 |
2023-08-12 |
mouse |
| David Porter, Emilie Faivre, Peter R Flatt, Christian Hölscher, Victor A Gaul. Actions of incretin metabolites on locomotor activity, cognitive function and in vivo hippocampal synaptic plasticity in high fat fed mice. Peptides. vol 35. issue 1. 2012-08-07. PMID:22465882. |
high-fat fed swiss to mice treated with glp-1(9-36)amide, gip(3-42) or exendin(9-39)amide (twice-daily for 60 days) did not exhibit any changes in bodyweight, non-fasting plasma glucose and plasma insulin concentrations or glucose tolerance compared with high-fat saline controls. |
2012-08-07 |
2023-08-12 |
mouse |
| Gina M Whitaker, Francis C Lynn, Christopher H S McIntosh, Eric A Accil. Regulation of GIP and GLP1 receptor cell surface expression by N-glycosylation and receptor heteromerization. PloS one. vol 7. issue 3. 2012-08-02. PMID:22412906. |
n-glycosylation is also required for expression of the gip receptor at the plasma membrane and efficient gip potentiation of glucose-induced insulin secretion from the ins-1 pancreatic beta cell line. |
2012-08-02 |
2023-08-12 |
human |
| Yasuhisa Mori, Takao Ohtsuka, Kosuke Tsutsumi, Takaharu Yasui, Junji Ueda, Shunichi Takahata, Masafumi Nakamura, Masao Tanak. Different incretin responses after pancreatoduodenectomy and distal pancreatectomy. Pancreas. vol 41. issue 3. 2012-07-31. PMID:22422137. |
glucagon-like peptide-1 (glp-1) and glucose-dependent insulinotropic polypeptide (gip) are known as incretins to stimulate insulin secretion. |
2012-07-31 |
2023-08-12 |
Not clear |
| T Nakamura, H Tanimoto, Y Mizuno, Y Tsubamoto, H Nod. Biological and functional characteristics of a novel low-molecular weight antagonist of glucose-dependent insulinotropic polypeptide receptor, SKL-14959, in vitro and in vivo. Diabetes, obesity & metabolism. vol 14. issue 6. 2012-07-23. PMID:22192426. |
gip plays a role in the glucose and lipid metabolism, and is associated with obesity and insulin resistance. |
2012-07-23 |
2023-08-12 |
Not clear |
| Kentaro Shoji, Tomohito Mizuno, Daisuke Shiiba, Tadanobu Kawagoe, Yuuki Mitsu. Effects of a meal rich in 1,3-diacylglycerol on postprandial cardiovascular risk factors and the glucose-dependent insulinotropic polypeptide in subjects with high fasting triacylglycerol concentrations. Journal of agricultural and food chemistry. vol 60. issue 10. 2012-06-29. PMID:22385133. |
postprandial tag, insulin, and gip concentrations were significantly lower after the dag meal compared with the tag meal in 26 subjects with fasting serum tag levels between 1.36 and 2.83 mmol/l. |
2012-06-29 |
2023-08-12 |
human |
| J Ma, A N Pilichiewicz, C Feinle-Bisset, J M Wishart, K L Jones, M Horowitz, C K Rayne. Effects of variations in duodenal glucose load on glycaemic, insulin, and incretin responses in type 2 diabetes. Diabetic medicine : a journal of the British Diabetic Association. vol 29. issue 5. 2012-06-22. PMID:22004512. |
we evaluated blood glucose, and plasma insulin, glp-1 and glucose-dependent insulinotropic polypeptide (gip) responses to intraduodenal glucose in type 2 diabetes, and compared these with data from healthy controls. |
2012-06-22 |
2023-08-12 |
Not clear |
| T Narita, H Yokoyama, R Yamashita, T Sato, M Hosoba, T Morii, H Fujita, K Tsukiyama, Y Yamad. Comparisons of the effects of 12-week administration of miglitol and voglibose on the responses of plasma incretins after a mixed meal in Japanese type 2 diabetic patients. Diabetes, obesity & metabolism. vol 14. issue 3. 2012-05-04. PMID:22051162. |
after 12-week administration of both drugs, during 2-h meal tolerance test, plasma glucose, serum insulin and total gip were significantly decreased and active glp-1 was significantly increased. |
2012-05-04 |
2023-08-12 |
human |
| T Narita, H Yokoyama, R Yamashita, T Sato, M Hosoba, T Morii, H Fujita, K Tsukiyama, Y Yamad. Comparisons of the effects of 12-week administration of miglitol and voglibose on the responses of plasma incretins after a mixed meal in Japanese type 2 diabetic patients. Diabetes, obesity & metabolism. vol 14. issue 3. 2012-05-04. PMID:22051162. |
in all participants, the relative change in bw was positively correlated with that of insulin significantly and of gip with a weak tendency, but not of glp-1. |
2012-05-04 |
2023-08-12 |
human |
| Emilie Faivre, Alison Hamilton, Christian Hölsche. Effects of acute and chronic administration of GIP analogues on cognition, synaptic plasticity and neurogenesis in mice. European journal of pharmacology. vol 674. issue 2-3. 2012-05-03. PMID:22115896. |
glucose-dependent insulinotropic polypeptide (gip), an incretin hormone, normalises insulin signalling in diabetes. |
2012-05-03 |
2023-08-12 |
mouse |
| Roberta Barone Lumaga, Danilo Azzali, Vincenzo Fogliano, Luca Scalfi, Paola Vitaglion. Sugar and dietary fibre composition influence, by different hormonal response, the satiating capacity of a fruit-based and a β-glucan-enriched beverage. Food & function. vol 3. issue 1. 2012-04-16. PMID:22057424. |
appetite ratings over 3 h post-breakfast and energy intakes at ad libitum lunch, blood glucose, insulin, ghrelin, pyy, glp-1, gip, and pp concentrations, and 24 h food intake, were assessed. |
2012-04-16 |
2023-08-12 |
human |
| Hélène Duez, Bertrand Cariou, Bart Stael. DPP-4 inhibitors in the treatment of type 2 diabetes. Biochemical pharmacology. vol 83. issue 7. 2012-04-10. PMID:22172989. |
these agents inhibit the degradation of the incretins glucagon-like peptide-1 (glp-1) and glucose-dependent insulinotropic polypeptide (gip) and hence potentiate glucose-dependent insulin secretion. |
2012-04-10 |
2023-08-12 |
Not clear |
| Jens Juul Holst, Maria A McGil. Potential new approaches to modifying intestinal GLP-1 secretion in patients with type 2 diabetes mellitus: focus on bile acid sequestrants. Clinical drug investigation. vol 32. issue 1. 2012-04-03. PMID:21958333. |
the incretin hormones glucose-dependent insulinotropic polypeptide (gip) and glucagon-like peptide-1 (glp-1) stimulate glucose-induced insulin secretion; however, in patients with type 2 diabetes, the incretin system is impaired by loss of the insulinotropic effects of gip as well as a possible reduction in secretion of glp-1. |
2012-04-03 |
2023-08-12 |
mouse |